CONTI, PAOLA
 Distribuzione geografica
Continente #
EU - Europa 6.953
NA - Nord America 5.126
AS - Asia 3.094
SA - Sud America 221
AF - Africa 48
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 2
Totale 15.456
Nazione #
US - Stati Uniti d'America 5.036
GB - Regno Unito 2.215
IT - Italia 1.577
CN - Cina 1.323
DE - Germania 900
SG - Singapore 659
RU - Federazione Russa 554
SE - Svezia 549
IN - India 313
TR - Turchia 227
IE - Irlanda 209
KR - Corea 182
UA - Ucraina 174
FR - Francia 158
NL - Olanda 135
FI - Finlandia 129
BR - Brasile 107
EU - Europa 93
HK - Hong Kong 83
ID - Indonesia 71
CA - Canada 70
DK - Danimarca 66
ES - Italia 65
CO - Colombia 59
JP - Giappone 58
VN - Vietnam 41
BE - Belgio 36
CH - Svizzera 36
PH - Filippine 35
GR - Grecia 33
PL - Polonia 23
AR - Argentina 20
TW - Taiwan 18
AT - Austria 17
MX - Messico 17
PT - Portogallo 17
RO - Romania 15
CL - Cile 13
EG - Egitto 12
PK - Pakistan 12
TH - Thailandia 11
AU - Australia 10
CZ - Repubblica Ceca 9
IR - Iran 9
MA - Marocco 9
NO - Norvegia 7
SC - Seychelles 7
EC - Ecuador 6
JO - Giordania 6
SA - Arabia Saudita 6
HU - Ungheria 5
IL - Israele 5
PE - Perù 5
AE - Emirati Arabi Uniti 4
EE - Estonia 4
IQ - Iraq 4
LV - Lettonia 4
MY - Malesia 4
PY - Paraguay 4
SK - Slovacchia (Repubblica Slovacca) 4
UZ - Uzbekistan 4
AM - Armenia 3
BO - Bolivia 3
DZ - Algeria 3
HR - Croazia 3
LK - Sri Lanka 3
MK - Macedonia 3
VE - Venezuela 3
ZA - Sudafrica 3
BG - Bulgaria 2
GH - Ghana 2
KZ - Kazakistan 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
MU - Mauritius 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
SN - Senegal 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AO - Angola 1
AZ - Azerbaigian 1
BD - Bangladesh 1
BH - Bahrain 1
CR - Costa Rica 1
ET - Etiopia 1
GL - Groenlandia 1
GN - Guinea 1
IS - Islanda 1
KE - Kenya 1
KH - Cambogia 1
ML - Mali 1
MN - Mongolia 1
MO - Macao, regione amministrativa speciale della Cina 1
PA - Panama 1
SD - Sudan 1
TM - Turkmenistan 1
UY - Uruguay 1
Totale 15.548
Città #
Southend 2.041
Milan 701
Singapore 453
Chandler 440
Seattle 363
Princeton 293
Wilmington 289
Fairfield 283
Beijing 273
Ashburn 251
Ann Arbor 241
Santa Clara 224
Council Bluffs 219
Dublin 202
Woodbridge 160
Dearborn 152
Hanover 149
Frankfurt am Main 144
Nanjing 144
Mountain View 134
Houston 132
Jacksonville 117
Redmond 114
Boardman 90
Cambridge 87
Bengaluru 85
Des Moines 72
Redwood City 72
Sakarya 69
Somerville 68
Jinan 66
Guangzhou 64
Shanghai 64
Phoenix 61
Grafing 60
Shenyang 59
Munich 55
Serra 55
Andover 51
Bogotá 51
Toronto 48
Hong Kong 47
New York 47
Jakarta 38
Los Angeles 32
Athens 31
Berlin 31
Nanchang 31
Rome 31
Brussels 30
Hebei 30
Eitensheim 29
Tianjin 29
Changsha 28
Hamburg 28
Murcia 28
Hangzhou 27
Odernheim 26
San Diego 25
Helsinki 24
Verona 24
Medford 22
Jiaxing 21
Nuremberg 20
Fuzhou 19
Istanbul 19
Ningbo 19
Wuhan 19
Bühl 18
Madrid 18
Monza 18
Siracusa 18
Sunnyvale 18
Bologna 16
Seoul 16
Zhengzhou 16
Mumbai 15
Roxbury 15
Genoa 14
Portici 14
São Paulo 14
Auburn Hills 13
London 13
Quanzhou 13
Amsterdam 12
Cinisello Balsamo 12
Tokyo 12
Baden 11
Dong Ket 11
Hefei 11
Paris 11
Turin 11
Bitonto 10
Craco 10
Hyderabad 10
Kent 10
Kunming 10
Pune 10
Vienna 10
Bern 9
Totale 9.870
Nome #
Inhibition of SIRT1 deacetylase and p53 activation uncouples the anti-inflammatory and chemopreventive actions of NSAIDs 329
Folates in Trypanosoma brucei: achievements and opportunities 247
Covalent inhibitors of GAPDH : From unspecific warheads to selective compounds 247
Marine microorganisms as source of stereoselective esterases and ketoreductases : kinetic resolution of a prostaglandin intermediate 233
Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof 227
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 226
Structural basis of subunit-selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits 225
An efficient continuous flow process for the synthesis of a non-conventional mixture of fructooligosaccharides 220
γ-Glutamyl-dipeptides : Easy tools to rapidly probe the stereoelectronic properties of the ionotropic glutamate receptor binding pocket 210
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule 196
Synthesis and structure-activity relationships in a set of new antimuscarinic agents 194
The Glial Glutamate Transporter 1 (GLT1) is Expressed by Pancreatic beta-Cells and Prevents Glutamate-Induced beta-Cell Death 193
Biotransformation with whole microbial systems in a continuous flow reactor : resolution of (RS)-flurbiprofen using Aspergillus oryzae by direct esterification with ethanol in organic solvent 192
Chemoenzymatic synthesis in flow reactors: a rapid and convenient preparation of Captopril 191
3-Carboxy-pyrazolinalanine as a new scaffold for developing potent and selective NMDA receptor antagonists 187
The impact of Chirality on Medicinal Chemistry 181
Flow-based stereoselective reduction of ketones using an immobilized ketoreductase/glucose dehydrogenase mixed bed system 181
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 180
Innovative enzymatic (R,S)-flurbiprofen resolution in continuous flow reactor with lyophilized cells of Aspergillus oryzae 178
The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death 176
Sweet-and-salty biocatalysis : fructooligosaccharides production using Cladosporium cladosporioides in seawater 172
Efficient synthesis of novel glutamate homologues and investigation of their affinity and selectivity profile at ionotropic glutamate receptors 170
Use of Immobilized Amine Transaminase from Vibrio fluvialis under Flow Conditions for the Synthesis of (S)-1-(5-Fluoropyrimidin-2-yl)-ethanamine 167
Two examples of high-efficient and green biotransformations 166
Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid 165
Synthesis of unusual isoxazoline containing β and γ-dipeptides as potential glutamate receptor ligands 160
Synthesis, Binding Affinity at Glutamic Acid Receptors, Neuroprotective Effects, and Molecular Modeling Investigation of Novel Dihydroisoxazole Amino Acids 159
Design of Cyclopentaisoxazoline Amino Acids as Conformationally Constrained Agonists at Glutamate Receptors 158
Immobilized enzyme reactors based on nucleoside phosphorylases and 2′-deoxyribosyltransferase for the in-flow synthesis of pharmaceutically relevant nucleoside analogues 158
Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters 157
A regioselective route to 5-substituted pyrazole- and pyrazoline-3-phosphonic acids and esters 156
Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro 156
An enzymatic flow-based preparative route to vidarabine 155
CTP synthetase inhibitors as new potential agents for the treatment of African Trypanosomiasis : synthesis and in vitro/in vivo evaluation of trypanocidal activity of 3-Br-Acivicin 154
Synthesis of novel pyrrolo[3,4-d]pyrazole-dicarboxylic acids and evaluation of their interaction with glutamate receptors 152
Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity 152
Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria 149
Neuroprotective effects of the novel glutamate transporter inhibitor (-)-3-hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylic acid, which preferentially inhibits reverse transport (glutamate release) compared with glutamate reuptake 148
Bicyclic γ-amino acids as inhibitors of γ-aminobutyrate aminotransferase 147
Synthesis and Anticonvulsant Activity of Novel Bicyclic Acidic Amino Acids 146
Enzymatic continuous-flow preparation of nature-inspired phenolic esters as antiradical and antimicrobial noagents 145
Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid 145
Synthesis and biological evaluation of new amino acids structurally related to the antitumor agent acivicin 143
A new chemoenzymatic approach to the synthesis of latanoprost and bimatoprost 142
Flow-based biocatalysis : application to peracetylated arabinofuranosyl-1,5-arabinofuranose synthesis 141
(-)-HIP-A and (+)-HIP-B: investigation of the pharmacological profile and potential therapeutic applications 136
Regioselective Preparation of Functionalized Isoxazoline Derivatives, Key Intermediates in the Synthesis of Selective NMDA Receptor Antagonists 136
Synthesis of new Delta(2)-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists 134
Synthesis and pharmacological characterization of new analogs of broxaterol 134
Synthesis and pharmacological characterization of the selective GluK1 radioligand (: S)-2-amino-3-(6-[3H]-2,4-dioxo-3,4-dihydrothieno[3,2- d] pyrimidin-1(2 H)-yl)propanoic acid ([3H]-NF608) 134
Synthesis of Novel N1-Substituted Bicyclic Pyrazole Amino Acids and Evaluation of Their Interaction with Glutamate Receptors 133
Design and synthesis of novel isoxazole-based HDAC inhibitors 128
Synthesis of L-tricholomic acid analogues and pharmacological characterization at ionotropic glutamate receptors 128
One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water 127
An efficient method for the lipase-catalysed resolution and in-line purification of racemic flurbiprofen in a continuous-flow reactor 127
Design of Novel Conformationally Restricted Analogues of Glutamic Acid 125
Synthesis and in vitro/in vivo Evaluation of the Antitrypanosomal Activity of 3-Bromoacivicin, a Potent CTP Synthetase Inhibitor 125
The chemoenzymatic continuous-flow synthesis of captopril 125
Synthesis of novel enantiopure 2-isoxazoline and 2-pyrazoline amino acids and their activity at glutamic acid receptors and transporters 123
Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds 123
Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents 122
Synthesis of Conformationally Constrained Glutamic Acid Homologues and Investigation of Their Pharmacological Profiles 121
Inhibition of Rhodesain as a Novel Therapeutic Modality for Human African Trypanosomiasis 121
An improved synthesis of enantiomerically pure CIP-AS, a potent and selective AMPA-kainate receptor agonist 120
A regioselective route to 5-substituted isoxazoline-3-phosphonates 118
Chemoenzymatic synthesis of the enantiomers of desoxymuscarine 117
Enzymatic synthesis of ω-carboxy-β-hydroxy-(L)-α-amino acids 116
A new chemoenzymatic approach to the synthesis of Latanoprost and Bimatoprost 116
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 115
Design, synthesis, and pharmacological characterization of novel, potent NMDA receptor antagonists 114
Pichia Glucozyma: a powerful biocatalyst for enantioselective reduction of ketones 114
Synthesis of new β- and γ-benzyloxy-S-glutamic acid derivatives and evaluation of their activity as inhibitors of excitatory amino acid transporters 113
Design, synthesis and biological characterization of PfGAPDH inhibitors 112
Synthesis and binding affinity of new muscarinic ligands structurally related to oxotremorine 111
Dissociation of [3H]L-Glutamate Uptake from L-Glutamate-Induced [3H]D-Aspartate release by 3-Hydroxy-4,5,6,6atetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylic Acid and 3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-6-carboxylic Acid, Two Conf 110
Stereoselective synthesis of 4-amino-3-hydroxy-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-4-carboxylic acid, a conformationally constrained analogue of aspartic acid 109
Synthesis and Biological Evaluation of CTP Synthetase Inhibitors as Potential Agents for the Treatment of African Trypanosomiasis 108
A highly efficient flow reactor process for the synthesis of N-Boc-3,4-dehydro-L-proline methyl ester 107
Design of a fully automated system for the synthesis of pharmaceutically relevant building blocks exploiting immobilized Rhodotorula rubra and new solvent systems 107
Synthetic approach to and biological relevance of differently 3-subsituted delta2-isoxazolines and isoxazoles 106
A novel simplified synthesis of Acivicin 106
Use of a O-benzyl-(S)-serine containing eluent for the efficient ligand-exchange chromatography-based enantioseparation of constrained glutamate receptor ligands 106
Synthesis of 3-hydroxy- and 3-carboxy-Delta(2)-isoxazoline amino acids and evaluation of their interaction with GABA receptors and transporters 105
Synthesis of TBOA homologues and evaluation of their activity as Glutamate transporter inhibitors 104
Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors 104
Design and synthesis of novel acidic amino acids acting at glutamate receptors and transporters 103
Synthesis and pharmacological profile at Glu receptors of the enantiomeric pure forms of erytro- and threo- tricholomic acid 103
Enantiomeric forms of (±)-HIP-A and (±)-HIP-B : synthesis and evalutation of their activity at the excitatory amino acids 100
Synthesis of new bicyclic analogues of glutamic acid 100
Inspired by Nature : The 3-Halo-4,5-dihydroisoxazole Moiety as a Novel Molecular Warhead for the Design of Covalent Inhibitors 100
A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents 97
Development of Radiolabeled Ligands Targeting the Glutamate Binding Site of the N-Methyl-d-aspartate Receptor as Potential Imaging Agents for Brain 97
Enantiopure stereoisomeric homologues of glutamic acid: chemoenzymatic synthesis and assignment of their absolute configurations 96
Synthesis of (3-hydroxy-pyrazolin-5-yl)glycine based ligands interacting with ionotropic glutamate receptors 94
Synthesis and in Vitro Pharmacology of Novel Heterocyclic Muscarinic Ligands 92
Drug Discovery Targeting Amino Acid Racemases 92
Synthesis and enantiopharmacology of new AMPA-kainate receptor agonists 92
Synthesis and functional characterization of novel derivatives related to oxotremorine and oxotremorine-M 91
Evading Pgp activity in drug-resistant cancer cells : a structural and functional study of antitubulin furan metotica compounds 91
Synthesis and Biochemical Evaluation of Δ2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors 90
Totale 14.254
Categoria #
all - tutte 52.939
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.939


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020682 0 0 0 0 0 0 0 0 262 222 90 108
2020/20211.701 59 154 119 73 177 132 97 78 197 162 337 116
2021/20221.918 156 60 77 76 129 307 196 142 144 207 144 280
2022/20231.929 250 148 161 185 235 344 52 137 205 38 130 44
2023/20241.382 63 113 77 95 270 66 81 111 46 91 172 197
2024/20252.201 176 340 116 364 346 131 84 454 190 0 0 0
Totale 16.690