Flow reactor technology represents one of the new strategies introduced to advance the sustainability of organic synthesis and shows many advantages compared to the batch methods (e.g. , increased safety, high control of reaction parameters, reduced manual handling, in-line purifications, reaction telescoping). For these reasons, continuous-flow synthesis is receiving increasing attention also in the pharmaceutical industry and, as a result, in the last years many new flow-based routes have been designed towards commercially available APIs
The chemoenzymatic continuous-flow synthesis of captopril / F. Dall'Oglio, A. Pinto, V. De Vitis, F. Molinari, D. Romano, P. Conti, L. Tamborini. ((Intervento presentato al 24. convegno National Meeting in Medicinal Chemistry 2016 (NMMC 2016) tenutosi a Perugia nel 2016.
The chemoenzymatic continuous-flow synthesis of captopril
F. Dall'Oglio
;A. PintoSecondo
;V. De Vitis;F. Molinari;D. Romano;P. ContiPenultimo
;L. TamboriniUltimo
2016
Abstract
Flow reactor technology represents one of the new strategies introduced to advance the sustainability of organic synthesis and shows many advantages compared to the batch methods (e.g. , increased safety, high control of reaction parameters, reduced manual handling, in-line purifications, reaction telescoping). For these reasons, continuous-flow synthesis is receiving increasing attention also in the pharmaceutical industry and, as a result, in the last years many new flow-based routes have been designed towards commercially available APIsFile | Dimensione | Formato | |
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