gamma-Glutamyl-dipeptides, built by condensing the distal carboxylate of L-Glu (or D-Glu) onto a series of differently functionalized amino acids, were prepared and used as tools for rapidly probing the stereo electronic properties of iGluRs, searching for subtype-selective ligands.
γ-Glutamyl-dipeptides : Easy tools to rapidly probe the stereoelectronic properties of the ionotropic glutamate receptor binding pocket / L. Tamborini, V. Nicosia, P. Conti, F. Dall'Oglio, C. De Micheli, B. Nielsen, A.A. Jensen, D.S. Pickering, A. Pinto. - In: TETRAHEDRON. - ISSN 0040-4020. - 72:51(2016), pp. 8486-8492. [10.1016/j.tet.2016.11.025]
γ-Glutamyl-dipeptides : Easy tools to rapidly probe the stereoelectronic properties of the ionotropic glutamate receptor binding pocket
L. TamboriniPrimo
;V. NicosiaSecondo
;P. Conti;F. Dall'Oglio;C. De Micheli;A. Pinto
2016
Abstract
gamma-Glutamyl-dipeptides, built by condensing the distal carboxylate of L-Glu (or D-Glu) onto a series of differently functionalized amino acids, were prepared and used as tools for rapidly probing the stereo electronic properties of iGluRs, searching for subtype-selective ligands.
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Tetrahedron 2016.pdf
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