PICCOLELLA, MARGHERITA
 Distribuzione geografica
Continente #
EU - Europa 14.852
NA - Nord America 8.633
AS - Asia 8.532
SA - Sud America 732
AF - Africa 228
OC - Oceania 60
Continente sconosciuto - Info sul continente non disponibili 4
Totale 33.041
Nazione #
US - Stati Uniti d'America 8.339
IT - Italia 6.803
DE - Germania 3.076
CN - Cina 2.750
SG - Singapore 2.396
GB - Regno Unito 1.947
VN - Vietnam 727
HK - Hong Kong 708
RU - Federazione Russa 584
BR - Brasile 543
SE - Svezia 488
FR - Francia 440
NL - Olanda 436
BD - Bangladesh 393
IN - India 386
KR - Corea 280
JP - Giappone 226
TR - Turchia 213
CA - Canada 184
IE - Irlanda 179
FI - Finlandia 169
UA - Ucraina 145
ID - Indonesia 133
CI - Costa d'Avorio 121
DK - Danimarca 118
BE - Belgio 69
PL - Polonia 64
MX - Messico 62
TW - Taiwan 62
EU - Europa 61
ES - Italia 60
AU - Australia 57
CH - Svizzera 52
CO - Colombia 51
AR - Argentina 46
AT - Austria 44
IL - Israele 38
ZA - Sudafrica 37
IQ - Iraq 31
GR - Grecia 30
PK - Pakistan 27
PH - Filippine 25
CL - Cile 24
EC - Ecuador 23
MY - Malesia 18
RO - Romania 16
SA - Arabia Saudita 16
HU - Ungheria 15
SI - Slovenia 15
EG - Egitto 14
AL - Albania 13
UZ - Uzbekistan 13
IR - Iran 12
PE - Perù 12
PT - Portogallo 12
VE - Venezuela 12
NO - Norvegia 11
KE - Kenya 10
CR - Costa Rica 9
MA - Marocco 9
UY - Uruguay 9
KZ - Kazakistan 8
LT - Lituania 8
LU - Lussemburgo 8
TH - Thailandia 8
AE - Emirati Arabi Uniti 7
NP - Nepal 7
PY - Paraguay 7
JM - Giamaica 6
JO - Giordania 6
RS - Serbia 6
AZ - Azerbaigian 5
CZ - Repubblica Ceca 5
ET - Etiopia 5
HN - Honduras 5
HR - Croazia 5
ME - Montenegro 5
SC - Seychelles 5
TN - Tunisia 5
TT - Trinidad e Tobago 5
AD - Andorra 4
BG - Bulgaria 4
GT - Guatemala 4
MO - Macao, regione amministrativa speciale della Cina 4
OM - Oman 4
PA - Panama 4
SM - San Marino 4
BA - Bosnia-Erzegovina 3
BH - Bahrain 3
BO - Bolivia 3
CY - Cipro 3
DZ - Algeria 3
KW - Kuwait 3
LB - Libano 3
LV - Lettonia 3
NZ - Nuova Zelanda 3
PR - Porto Rico 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
AM - Armenia 2
Totale 33.045
Città #
Hanover 2.046
Southend 1.560
Singapore 1.406
Milan 1.205
Ashburn 1.037
Hong Kong 590
Rome 589
San Jose 561
Dallas 480
Beijing 452
Chandler 424
Frankfurt am Main 410
Fairfield 338
Council Bluffs 313
New York 298
Seattle 295
Hefei 239
Santa Clara 233
Ho Chi Minh City 226
Los Angeles 225
Wilmington 219
Ann Arbor 186
Princeton 183
Hanoi 179
Dublin 176
Woodbridge 173
Florence 149
Houston 148
Bari 142
Turin 137
Naples 134
Bengaluru 130
Cambridge 127
Shanghai 126
Abidjan 121
Lauterbourg 121
Palermo 121
Munich 117
Jakarta 114
Seoul 108
Jacksonville 105
Guangzhou 104
Boardman 99
Dearborn 96
Moscow 89
Nanjing 84
Chicago 81
Tokyo 81
Buffalo 79
Phoenix 79
Redmond 77
Bologna 74
Helsinki 67
Istanbul 67
Des Moines 64
Grafing 62
Padova 62
The Dalles 61
Jinan 60
Brescia 59
Cangzhou 59
Verona 59
Mountain View 58
Redwood City 58
São Paulo 58
Zhengzhou 53
Atlanta 52
Shenyang 51
Toronto 51
Genoa 50
Messina 50
Catania 49
Perugia 49
Da Nang 48
Nuremberg 45
Andover 43
Somerville 43
Sakarya 41
Montreal 39
Philadelphia 39
Bogotá 38
Tianjin 38
Changsha 37
Medford 37
Hangzhou 36
Wuhan 36
Fuzhou 35
London 35
Taranto 35
Warsaw 35
Boston 32
Magenta 32
Mumbai 32
Trento 32
Delhi 31
Haiphong 31
Taichung 31
Bergamo 29
Brussels 29
Nanchang 29
Totale 19.053
Nome #
Becker : Il mondo della cellula 5.560
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration 1.209
Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases 621
The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases 554
Autophagic and Proteasomal Mediated Removal of Mutant Androgen Receptor in Muscle Models of Spinal and Bulbar Muscular Atrophy 552
Transforming Growth Factor beta 1 signaling is altered in the spinal cord and muscle of amyotrophic lateral sclerosis mice and patients 538
Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells 521
The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells 501
Retinoic Acid Downregulates HSPB8 Gene Expression in Human Breast Cancer Cells MCF-7 470
Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases 447
Expression and differential effects of the activation of glucocorticoid receptors in mouse gonadotropin-releasing hormone neurons 333
suPAR, a soluble form of urokinase plasminogen activator receptor, inhibits human prostate cancer cell growth and invasion 316
Antiproliferative effect of mifepristone ({RU}486) on human neuroblastoma cells ({SK}-N-{SH}): in vitro and in vivo studies 315
In vitro chronic administration of ERbeta selective ligands and prostate cancer cell growth : hypotheses on the selective role of 3beta-adiol in AR-positive RV1 cells 308
Estrogen receptor β and the progression of prostate cancer : role of 5{alpha}-androstane-3β,17β-diol 305
Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy 302
The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases 296
Analysis of the autophagic response in models of KIF5A-related neurodegeneration 295
Enhanced Clearance of Neurotoxic Misfolded Proteins by the Natural Compound Berberine and Its Derivatives 282
Caratterizzazione del sistema attivatore del plasminogeno nella progressione metastatica del cancro prostatico umano 278
Molecules capable to induce neuroprotection via lysophagy activation 278
Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice 275
The regulation of the small heat shock protein B8 in misfolding protein diseases causing motoneuronal and muscle cell death 264
Tolerance of chronic hypercapnia by the European eel Anguilla anguilla 261
Role of glucocorticoid receptors in mouse neurons secreting gonadotropin releasing hormone 258
HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies 257
Chaperone Assisted Selective Autophagy (CASA) a potential target for therapeutics in motoneuron diseases 250
A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases 246
Molecular mechanisms in KIF5A-related neurodegeneration 243
Small heat shock protein B8: from cell functions to its involvement in diseases and potential therapeutic applications 239
The Role of HSPB8, a Component of the Chaperone-Assisted Selective Autophagy Machinery, in Cancer 236
TDP-43 PROTEINOPATHIES: THE ROLE OF EXTRACELLULAR VESICLES 235
Alternative Translation Initiation as a novel strategy to block toxicity of the mutant Androgen Receptor in SBMA 234
Motor neuron degeneration in spinal and bulbar muscular atrophy: molecular approaches to counteract mutant androgen receptor neurotoxicity 234
Multiple Roles of Transforming Growth Factor Beta in Amyotrophic Lateral Sclerosis 230
Estrogen receptor beta and the progression of prostate cancer - role of 5alpha-androstane-3beta,17beta-diol (3beta-Adiol) 229
Identification of new HSPB8 variants linked to familial Amiotrophic Lateral Sclerosis 224
Generation of novel induced pluripotent stem cell models for the study of spinocerebellar ataxia type 17 223
Pathogenic variants of Valosin Containing Protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells 216
The protein quality control system in motoneuron diseases 212
Valosin Containing Protein (VCP): A Multistep Regulator of Autophagy 211
ALS-associeted VCP-mutants lead to lysosome damage 209
VCP mutants cause lysosomal alterations and autophagy induction in ALS-neuronal model 209
The clearance of aggregated TDP-43 responsible for ALS/FTD diseases 208
Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy 202
The product of X-linked Kallmann's syndrome gene (KAL1) affects the migratory activity of Gonadotropin-Releasing Hormone (GnRH)-producing neurons 202
Effect of Hspb8 deletion in the skeletal muscle of a mouse model for Amyotrophic Lateral Sclerosis 200
Insights on human small heat shock proteins and their alterations in diseases 200
Neurodegenerative Disease-Associated TDP-43 Fragments Are Extracellularly Secreted with CASA Complex Proteins 198
How PQC inhibition modulates miRNA loading in large and small extracellular vesicles 195
STUB1 mutants effect on TBP behavior in digenic spinocerebellar ataxia type 17 195
VCP modulation rescues C9ORF72 pathological features in ALS-neuronal models 192
Chaperone mediated autophagy responds to macroautophagy inhibition in motor neuron diseases 192
VCP ALS-mutants induce lysosomal damage and autophagy activation 189
Mechanism of paroxetine-mediated autophagic induction in cell models of ALS/FTD 187
Role of glucocorticoids in the migration of immature LHRH neurons 187
Altered molecular and cellular mechanisms in KIF5A-associated neurodegenerative or neurodevelopmental disorders 186
Novel pathogenic mechanism of ALS-associated VCP- mutants 186
Role of a soluble form of urokinase plasminogen-activator receptor in the control of human prostate cancer cell growth and invasion 184
Antiproliferative action of RU486 on human neuroblastoma cells (SK-N-SH) 184
Role of estrogen receptor beta in the progression of prostate cancer 183
Extracellular vesicles cooperate with PQC system for the clearance of TDP-43 species associated with ALS and FTD 182
Ozarelix, a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors 178
The role of autophagy-lysosomal pathway in motor neuron diseases 176
Expression and role of glucocorticoid receptors in mouse neurons secretine gonadotropin releasing hormons 176
Dexamethasone blocks the migration of the human neuroblastoma cell line SK-N-SH 176
Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases 175
Cellular mechanisms regulating uPA in hormone refractory prostate cancer : role of suPAR, a solubile form of Urokinase Plasminogen-Activator Receptor 174
PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer 173
Regolazione del sistema attivatore del plasminogeno da parte degli ormoni glucocorticoidi nella progressione metastatica del cancro prostatico 172
Luminescent Iridium-Peptide Nucleic Acid Bioconjugate as Photosensitizer for Singlet Oxygen Production toward a Potential Dual Therapeutic Agent 170
Role of Ozarelix in the control of proliferation, migration and invasion of human prostate cancer cell lines 170
Antitumor effects of carnertinib in castration resistant prostate cancer models : a comparative study with erlotinib 170
Chaperone-assisted selective autophagy in Health and Disease 169
VCP mutants induce lysosomal damage and autophagy activation in amyotrophic lateral sclerosis (ALS) 169
Shared behaviours of KIF5A frameshift mutants in neurodevelopment and neurodegeneration 168
GnRH agonists and antagonists decrease the metastatic progression of human prostate cancer cell lines by inhibiting the plasminogen activator system 167
One gene, many phenotypes: investigating KIF5A-linked neurodegeneration mechanisms 166
Investigating the molecular mechanisms involved in KIF5A-related neurodegeneration 166
Targeting androgen receptor stability and degradation: approaches for developing a therapy for spinal and bulbar muscular atrophy 166
Insights into KIF5A-related pathways to neurodegeneration 165
AN Ir-PNA BIOCONJUGATE FOR 1O2 PRODUCTION IN PDT: TOWARD A POTENTIAL DUAL THERAPEUTIC AGENT 163
Dexamethasone modulates differentiation and motility of SK-N-SH human neuroblastoma cells 163
New insight on the molecular aspects of glucocorticoid effects in nervous system development 162
Characterization of two new mutations in the small Heat Shock protein B8 HSPB8 and impact in Amyotrophic Lateral Sclerosis cell models 162
Mutant Androgen Receptor Alternative Translation Initiation as novel strategy to block toxicity in SBMA. 161
Dexamethasone blocks the migration of the human neuroblastoma cell line SK-N-SH 161
In vivo growth properties and molecular marker expression of DU145 human prostate tumor cells expressing recombinant androgen receptor 160
Role of estrogen receptor β in the pathogenesis and progression of prostate cancer 158
Modulators of Estrogen Receptor inhibit proliferation and migration of prostate cancer cells 157
Lysosome quality control in health and neurodegenerative diseases 155
Effects of dietary fatty acid composition on metabolic rate and responses to hypoxia in the European eel (Anguilla anguilla) 153
VCP autophagic modulation rescues C9ORF72 pathological features in ALS-neuronal models 152
Motor neuron degeneration in Spinal and Bulbar Muscular Atrophy: molecular approaches to counteract mutant androgen receptor neurotoxicity 151
Proteotoxic responses in amyotrophic lateral sclerosis 150
HSPB8 counteracts tumor activity of BRAF- and NRAS-mutant melanoma cells by modulation of RAS-prenylation and autophagy 150
Preparation and characterization of a PNA-Ir(III) conjugate for 1O2 production in PDT 149
Molecular defects in KIF5A-linked neurodegenerative and neurodevelopmental diseases 148
Effetto degli analoghi del GnRH sul sistema attivatore del plasminogeno nella progressione metastatica del cancro prostatico umano 148
The small heat shock protein B8 (HSPB8) removes dipeptides produced in C9ORF72-related neurodegenerative diseases 147
Totale 29.324
Categoria #
all - tutte 81.290
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 81.290


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021386 0 0 0 0 0 0 0 0 0 0 240 146
2021/20223.684 89 98 217 363 349 374 417 348 420 414 290 305
2022/20232.850 205 174 211 552 333 387 154 193 276 71 172 122
2023/20243.455 84 174 321 845 690 143 177 187 135 165 292 242
2024/20255.999 185 317 260 1.167 553 295 281 528 308 550 444 1.111
2025/202610.562 1.083 899 1.194 955 1.058 586 1.320 486 982 824 1.175 0
Totale 34.045