Nome |
# |
Caratterizzazione del sistema attivatore del plasminogeno nella progressione metastatica del cancro prostatico umano, file dfa8b98f-8925-748b-e053-3a05fe0a3a96
|
5.054
|
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration, file dfa8b99c-3736-748b-e053-3a05fe0a3a96
|
510
|
The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases, file dfa8b998-6657-748b-e053-3a05fe0a3a96
|
375
|
suPAR, a soluble form of urokinase plasminogen activator receptor, inhibits human prostate cancer cell growth and invasion, file dfa8b98e-8b1a-748b-e053-3a05fe0a3a96
|
344
|
Tolerance of chronic hypercapnia by the European eel Anguilla anguilla, file dfa8b98f-c2f5-748b-e053-3a05fe0a3a96
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260
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Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases, file dfa8b998-2e38-748b-e053-3a05fe0a3a96
|
229
|
The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases, file dfa8b998-8731-748b-e053-3a05fe0a3a96
|
185
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The regulation of the small heat shock protein B8 in misfolding protein diseases causing motoneuronal and muscle cell death, file dfa8b99f-2f92-748b-e053-3a05fe0a3a96
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184
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Antiproliferative effect of mifepristone ({RU}486) on human neuroblastoma cells ({SK}-N-{SH}): in vitro and in vivo studies, file dfa8b9a3-b3e6-748b-e053-3a05fe0a3a96
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173
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Insights into the neurodegenerative mechanisms associated with KIF5A mutations, file 56680d93-303f-47df-b795-36bf6c8530d4
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161
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Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases, file dfa8b995-01cf-748b-e053-3a05fe0a3a96
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161
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Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy, file dfa8b993-1c77-748b-e053-3a05fe0a3a96
|
151
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The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells, file dfa8b997-422e-748b-e053-3a05fe0a3a96
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146
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Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells, file dfa8b99b-b6d6-748b-e053-3a05fe0a3a96
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144
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How PQC inhibition modulates miRNA loading in large and small extracellular vesicles, file 21b0955f-899c-471d-9dd4-58f91281cc38
|
140
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The Role of HSPB8, a Component of the Chaperone-Assisted Selective Autophagy Machinery, in Cancer, file dfa8b9a5-4190-748b-e053-3a05fe0a3a96
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140
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The protein quality control system in motoneuron diseases, file dfa8b992-881d-748b-e053-3a05fe0a3a96
|
136
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In vitro chronic administration of ERbeta selective ligands and prostate cancer cell growth : hypotheses on the selective role of 3beta-adiol in AR-positive RV1 cells, file dfa8b991-42e5-748b-e053-3a05fe0a3a96
|
135
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Autophagic and Proteasomal Mediated Removal of Mutant Androgen Receptor in Muscle Models of Spinal and Bulbar Muscular Atrophy, file dfa8b99f-4adc-748b-e053-3a05fe0a3a96
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131
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Enhanced Clearance of Neurotoxic Misfolded Proteins by the Natural Compound Berberine and Its Derivatives, file dfa8b9a1-f092-748b-e053-3a05fe0a3a96
|
107
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Multiple Roles of Transforming Growth Factor Beta in Amyotrophic Lateral Sclerosis, file dfa8b9a2-301d-748b-e053-3a05fe0a3a96
|
105
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A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases, file dfa8b9a3-0fed-748b-e053-3a05fe0a3a96
|
102
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Transforming Growth Factor beta 1 signaling is altered in the spinal cord and muscle of amyotrophic lateral sclerosis mice and patients, file dfa8b99e-ae71-748b-e053-3a05fe0a3a96
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101
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Pathogenic variants of Valosin Containing Protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells, file e9d18bb1-67a8-43d4-aa12-75d15b29ae6f
|
97
|
Retinoic Acid Downregulates HSPB8 Gene Expression in Human Breast Cancer Cells MCF-7, file dfa8b9a6-e4c0-748b-e053-3a05fe0a3a96
|
96
|
Neurodegenerative Disease-Associated TDP-43 Fragments Are Extracellularly Secreted with CASA Complex Proteins, file dfa8b9a9-da13-748b-e053-3a05fe0a3a96
|
95
|
TDP-43 PROTEINOPATHIES: THE ROLE OF EXTRACELLULAR VESICLES, file 27dc34a9-3d27-48c5-a369-e2d3c832a3ec
|
90
|
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration, file dfa8b99d-29d3-748b-e053-3a05fe0a3a96
|
84
|
Role of glucocorticoid receptors in mouse neurons secreting gonadotropin releasing hormone, file dfa8b990-8635-748b-e053-3a05fe0a3a96
|
75
|
Insights into KIF5A-related pathways to neurodegeneration, file 138261e4-6e69-4f83-a528-4b5dd6c3c8d9
|
72
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One gene, many phenotypes: investigating KIF5A-linked neurodegeneration mechanisms, file 86e3e1a7-695b-431f-8637-378366a4b8c6
|
65
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Insights on human small heat shock proteins and their alterations in diseases, file dfa8b9a9-ad26-748b-e053-3a05fe0a3a96
|
62
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Valosin Containing Protein (VCP): A Multistep Regulator of Autophagy, file dfa8b9a9-a227-748b-e053-3a05fe0a3a96
|
47
|
Large and small extracellular vesicles may contribute to the propagation of ALS and FTD carrying toxic TDP species and potentially harmful miRNAs, file 35c1fa66-e63a-4b28-9e47-290afca853c5
|
43
|
The role of autophagy-lysosomal pathway in motor neuron diseases, file bbf9e809-278b-41af-9e60-753362497db9
|
43
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HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies, file 4643b012-2d73-4531-9774-06eb91ee2634
|
42
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Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice, file d3a6c3cf-972a-4e04-b1d2-a62aba6a58be
|
39
|
Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases, file be05b08b-f354-4c6b-8379-4823c368429d
|
31
|
Analysis of the pathogenetic mechanisms involved in KIF5A-related neurodegenerative disorders, file dfa8b9a9-f163-748b-e053-3a05fe0a3a96
|
31
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Shared behaviours of KIF5A frameshift mutants in neurodevelopment and neurodegeneration, file d000fe03-ec7f-423f-9234-72bc7c9c72a9
|
27
|
VCP mutants cause lysosomal alterations and autophagy induction in ALS-neuronal model, file dfa8b9a7-aec2-748b-e053-3a05fe0a3a96
|
22
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Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases, file dfa8b9a6-bb65-748b-e053-3a05fe0a3a96
|
19
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Novel pathogenic mechanism of ALS-associated VCP- mutants, file dfa8b99e-4c66-748b-e053-3a05fe0a3a96
|
18
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Alternative Translation Initiation as a novel strategy to block toxicity of the mutant Androgen Receptor in SBMA, file 48b97ee8-b599-40f0-b48c-82852033f279
|
17
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Motor neuron degeneration in spinal and bulbar muscular atrophy: molecular approaches to counteract mutant androgen receptor neurotoxicity, file dfa8b9a0-408e-748b-e053-3a05fe0a3a96
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17
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Pathogenic variants of Valosin Containing Protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells, file dfa8b9aa-7aa2-748b-e053-3a05fe0a3a96
|
15
|
Identification of new HSPB8 variants linked to familial Amiotrophic Lateral Sclerosis, file dfa8b99c-6eb6-748b-e053-3a05fe0a3a96
|
14
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VCP ALS-mutants induce lysosomal damage and autophagy activation, file dfa8b9a7-83a9-748b-e053-3a05fe0a3a96
|
14
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Molecular mechanisms in KIF5A-related neurodegeneration, file 7775af56-ab02-4fc8-bf74-70a686f327a1
|
13
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Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases, file 84cb0293-2bbd-4a94-87ee-72cae0cd2891
|
13
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Mutant Androgen Receptor Alternative Translation Initiation as novel strategy to block toxicity in SBMA., file b5bf0d92-d46c-45e2-835c-c5c2f3d5714d
|
13
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Estrogen receptor β and the progression of prostate cancer : role of 5{alpha}-androstane-3β,17β-diol, file dfa8b990-8e69-748b-e053-3a05fe0a3a96
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13
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VCP mutants induce lysosomal damage and autophagy activation in amyotrophic lateral sclerosis (ALS), file dfa8b9a7-5ef1-748b-e053-3a05fe0a3a96
|
12
|
Retinoic Acid Downregulates HSPB8 Gene Expression in Human Breast Cancer Cells MCF-7, file dfa8b9a7-0b72-748b-e053-3a05fe0a3a96
|
11
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VCP modulation rescues C9ORF72 pathological features in ALS-neuronal models, file 58aaebf7-6e67-4471-837c-5eff5ce38e90
|
9
|
Innovative high throughput screening identifies HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases, file 69472320-619b-4c69-a538-f9b027c996f1
|
9
|
Proteotoxic responses in amyotrophic lateral sclerosis, file 845e09a9-63be-49cb-931e-3b6d8d8d06e9
|
9
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Expression and differential effects of the activation of glucocorticoid receptors in mouse gonadotropin-releasing hormone neurons, file dfa8b98f-aa6c-748b-e053-3a05fe0a3a96
|
9
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HSPB8 counteracts tumor activity of BRAF- and NRAS-mutant melanoma cells by modulation of RAS-prenylation and autophagy, file 6ec8b21e-a765-43c0-aff2-a16030a9bb1b
|
8
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Investigating the molecular mechanisms involved in KIF5A-related neurodegeneration, file 8f77a162-ac58-4c34-b798-bf74c414c4ec
|
8
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Molecules capable to induce neuroprotection via lysophagy activation, file dfa8b9a1-2e6d-748b-e053-3a05fe0a3a96
|
8
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Analysis of the autophagic response in models of KIF5A-related neurodegeneration, file dfa8b9a7-024d-748b-e053-3a05fe0a3a96
|
7
|
Expression and differential effects of the activation of glucocorticoid receptors in mouse gonadotropin-releasing hormone neurons, file dfa8b98f-b133-748b-e053-3a05fe0a3a96
|
4
|
Expression and differential effects of the activation of glucocorticoid receptors in mouse gonadotropin-releasing hormone neurons, file dfa8b98f-ba0c-748b-e053-3a05fe0a3a96
|
4
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Mechanism of paroxetine-mediated autophagic induction in cell models of ALS/FTD, file 680b2e1a-fd35-472a-a8e0-6f6d4a0a8f06
|
3
|
Frameshift mutations in the heat shock protein B8 cause its aggregation and impair proteostasis in neuromyopathies, file bf7c250c-b54a-480d-9c71-733e1609a9b9
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3
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Characterization of two new mutations in the small Heat Shock protein B8 HSPB8 and impact in Amyotrophic Lateral Sclerosis cell models, file dfa8b9a5-40b5-748b-e053-3a05fe0a3a96
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3
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New HSPB8 mutations related to Amyotrophic Lateral Sclerosis : characterization and impact in cell models of disease, file dfa8b9a5-435c-748b-e053-3a05fe0a3a96
|
3
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Effects of mutations of the pro-autophagic protein Heat Shock Protein B8 in motoneuron disease, file dfa8b9a5-65e8-748b-e053-3a05fe0a3a96
|
2
|
Frameshift mutations in the Heat Shock Protein B8 share common pathogenic mechanisms and impair proteostasis, file f3c0884b-c93f-4d06-b5de-e54fafc66317
|
2
|
Shared behaviours of KIF5A frameshift mutants in neurodevelopment and neurodegeneration, file 3b23df28-ff35-481b-b2e0-82de1f7ee43f
|
1
|
Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy, file dfa8b990-bf0d-748b-e053-3a05fe0a3a96
|
1
|
PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer, file dfa8b993-e2e4-748b-e053-3a05fe0a3a96
|
1
|
Chaperone Assisted Selective Autophagy (CASA) a potential target for therapeutics in motoneuron diseases, file dfa8b99b-58aa-748b-e053-3a05fe0a3a96
|
1
|
The small heat shock protein B8 (HSPB8) removes dipeptides produced in C9ORF72-related neurodegenerative diseases, file dfa8b99c-2693-748b-e053-3a05fe0a3a96
|
1
|
Chaperone mediated autophagy responds to macroautophagy inhibition in motor neuron diseases, file dfa8b99c-5862-748b-e053-3a05fe0a3a96
|
1
|
Totale |
10.521 |