CLEMENTI, FRANCESCO
CLEMENTI, FRANCESCO
DIPARTIMENTO DI FARMACOLOGIA, CHEMIOTERAPIA E TOSSICOLOGIA MEDICA (attivo dal 01/01/1960 al 26/04/2012)
Subnanomolar Affinity and Selective Antagonism at α7 Nicotinic Receptor by Combined Modifications of 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624)
2023 F. Bavo, M. Pallavicini, S. Pucci, R. Appiani, A. Giraudo, H. Oh, D.L. Kneisley, B. Eaton, L. Lucero, C. Gotti, F. Clementi, P. Whiteaker, C. Bolchi
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9- nicotinic ligands on glioblastoma cells
2022 S. Pucci, C. Bolchi, F. Bavo, M. Pallavicini, C. De Palma, M. Renzi, S. Fucile, R. Benfante, S. Di Lascio, D. Lattuada, J. Bessereau, M. D'Alessandro, V. Risson, M. Zoli, F. Clementi, C. Gotti
Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors
2021 S. Pucci, F. Fasoli, M. Moretti, R. Benfante, S. Di Lascio, P. Viani, A. Daga, T.J. Gordon, M. Mcintosh, M. Zoli, F. Clementi, C. Gotti
Persistent cognitive and affective alterations at late withdrawal stages after long-term intermittent exposure to tobacco smoke or electronic cigarette vapour : Behavioural changes and their neurochemical correlates
2020 L. Ponzoni, D. Braida, L. Carboni, M. Moretti, P. Viani, F. Clementi, M. Zoli, C. Gotti, M. Sala
Increased sensitivity to D9-THC-induced rewarding effects after seven-week exposure to electronic and tobacco cigarettes in mice
2019 L. Ponzoni, M. Moretti, D. Braida, M. Zoli, F. Clementi, P. Viani, M. Sala, C. Gotti
Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan
2018 F. Bavo, S. Pucci, F. Fasoli, C. Lammi, M. Moretti, V. Mucchietto, D. Lattuada, P. Viani, C. De Palma, R. Budriesi, I. Corradini, C. Dowell, J.M. Mcintosh, F. Clementi, C. Bolchi, C. Gotti, M. Pallavicini
alpha9- and alpha7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line
2018 V. Mucchietto, F.M. Fasoli, P. Susanna, M. Moretti, B. Roberta, A. Maroli, S. DI LASCIO, C. Bolchi, M. Pallavicini, D. Cheryl, M. Michael, F. Clementi, G. Cecilia
Nicotinic receptors increase cell proliferation and tumour progression in non-small cell lung cancer cell line
2015 V. Mucchietto, F. Fasoli, R. Benfante, A. Maroli, M.G. Cattaneo, F. Pistillo, M. Moretti, C. Bolchi, M. Pallavicini, F. Clementi, C. Gotti
Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization
2015 C. Matera, L. Pucci, C. Fiorentini, S. Fucile, C. Missale, G. Grazioso, F. Clementi, M. Zoli, M. De Amici, C. Gotti, C. Dallanoce
The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors
2014 L. Ponzoni, D. Braida, L. Pucci, A. Donzelli, F. Fasoli, I. Manfredi, R.L. Papke, C. Stokes, G. Cannazza, F. Clementi, C. Gotti, M. Sala
Nicotine-Modulated Subunit Stoichiometry Affects Stability and Trafficking of α3β4 Nicotinic Receptor
2013 F. Mazzo, F. Pistillo, G. Grazioso, F. Clementi, N. Borgese, C. Gotti, S.F. Colombo
Novel ligands for neuronal nicotinic receptor subtypes: synthetic, pharmacological and molecular docking studies
2012 C. Matera, D.Y. Pomè, C.M.L. Dallanoce, G. Grazioso, L. Pucci, S. Fucile, C. Gotti, F. Clementi, M. De Amici
The enantiomers of epiboxidine and of two related analogs: Synthesis and estimation of their binding affinity at α4β2 and α7 neuronal nicotinic acetylcholine receptors
2012 C.M.L. Dallanoce, C. Matera, M. DE AMICI, L. Rizzi, L. Pucci, C. Gotti, F. Clementi, C. DE MICHELI
Synthesis and binding affinity at α4β2 and α7 nicotinic acetylcholine receptors of new analogs of epibatidine and epiboxidine containing the 7-azabicyclo[2.2.1]hept-2-ene ring system
2012 C. Dallanoce, C. Matera, L. Pucci, C. Gotti, F. Clementi, M. De Amici, C. De Micheli
Inflammation and neurological adverse drugs reactions : a case of long lasting impaired consciousness after oxatomide administration in a patient with gastroenteritis
2012 S. Antoniazzi, D. Cattaneo, V. Perrone, C. Carnovale, S. Cherubini, M. Mugolino, F. Clementi, G. Zuccotti, E. Clementi, S. Radice
New spirocyclic Δ2-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors
2011 C.M.L. Dallanoce, F. Frigerio, G. Grazioso, C. Matera, G.L. Visconti, M. DE AMICI, L. Pucci, F. Pistillo, S. Fucile, C. Gotti, F. Clementi, C. DE MICHELI
Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors
2011 L. Pucci, G. Grazioso, C. Dallanoce, L. Rizzi, C. De Micheli, F. Clementi, S. Bertrand, D. Bertrand, R. Longhi, M. De Amici, C. Gotti
Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS
2011 R. Benfante, R.A. Antonini, M. De Pizzol, C. Gotti, F. Clementi, M. Locati, D.M.M. Fornasari
11,2-bis-N-cytisinylethane (CC4), a new nicotinic partial agonist, blocks nicotine- and Δ-9-tetrahydrocannabinol-induced conditioned place preference in zebrafish
2011 A. Donzelli, D. Braida, R. Martucci, L. Pucci, F. Clementi, C. Gotti, M. Sala
Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl-Δ2-Isoxazoline Derivatives as Potent and Selective Agonists of α7 Nicotinic Acetylcholine Receptors
2011 C.M.L. Dallanoce, P. Magrone, C. Matera, F. Frigerio, G. Grazioso, M. DE AMICI, S. Fucile, V. Piccari, K. Frydenvang, L. Pucci, C. Gotti, F. Clementi, C. DE MICHELI