DI LASCIO, SIMONA
DI LASCIO, SIMONA
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
Leveraging Brain Organoids to Explore Neurodevelopmental Mechanisms in Congenital Central Hypoventilation Syndrome (CCHS)
2025 E. Piscitelli, S. Di Lascio, F. Chiesa, A. Chiodi, C. Cocola, P. Pelucchi, D. Gaglio, M. Bonanomi, R. Vanna, V. Alcolea Rodriguez, A. Lucia Cuadros Gamboa, M. Bertocchi, D. Fornasari, R. Benfante
Expression Deregulation of lncRNA PHOX2B-AS1 in the Pathogenesis of CCHS
2025 S. Di Lascio, E. Piscitelli, M. Bertocchi, F. Chiesa, A. Lucia Cuadros Gamboa, E. Mosca, P. Pelucchi, A. Chiodi, R. Benfante, D. Fornasari
The natural antisense lncRNA PHOX2B-AS1 in the pathogenesis and as potential drug target in Congenital Central Hypoventilation Syndrome (CCHS)
2025 R. Benfante, A.L. Cuadros Gamboa, M. Bertocchi, F. Chiesa, S. Di Lascio, D. Fornasari
Study of the function of the natural antisense lncRNA PHOX2B-AS1 in 2D and 3D iPSc derived neuronal models of Congenital Central Hypoventilation Syndrome
2025 S. Di Lascio, E. Piscitelli, A. Lucia Cuadros Gamboa, M. Bertocchi, F. Chiesa, A. Chiodi, E. Mosca, P. Pelucchi, R. Benfante, D. Fornasari
Generation of 2D and 3D iPSC-derived neuronal models for the study of Congenital Central Hypoventilation Syndrome (CCHS)
2024 A.L. Cuadros Gamboa, E. Piscitelli, M. Bertocchi, F. Chiesa, P. Pelucchi, S. Di Lascio, R. Benfante, D. Fornasari
2D and 3D iPSC-derived neuronal models for the study of the role of lncRNA PHOX2B-AS1 in the pathogenesis of Congenital Central Hypoventilation Syndrome
2024 M. Bertocchi, S. Di Lascio, A.L. Cuadros, F. Chiesa, E. Piscitelli, P. Pelucchi, D. Fornasari, R. Benfante
Study of the role of lncRNA PHOX2B-AS1 in the pathogenesis of Congenital Central Hypoventilation Syndrome
2024 M. Bertocchi, A.L. Cuadros Gamboa, F. Chiesa, R. Benfante, D. Fornasari, S. Di Lascio
iPSC-derived autonomic neurons for the study of the role of lncRNA PHOX2B-AS1 in the pathogenesis of Congenital Central Hypoventilation Syndrome
2024 M. Bertocchi, S. Di Lascio, A.L. Cuadros, F. Chiesa, E. Piscitelli, P. Pelucchi, R. Benfante, D. Fornasari
Pharmacotherapeutic advances in fibromyalgia: what’s new on the horizon?
2024 P. Sarzi-Puttini, V. Giorgi, S. Sirotti, L. Bazzichi, D. Lucini, S. Di Lascio, G. Pellegrino, D. Fornasari
Inflammatory or non-inflammatory pain in inflammatory arthritis – How to differentiate it?
2024 P. Sarzi-Puttini, G. Pellegrino, V. Giorgi, S.F. Bongiovanni, G. Varrassi, S. Di Lascio, D. Fornasari, S. Sirotti, M. Di Carlo, F. Salaffi
Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS
2024 D. Diana, L. Pirone, L. Russo, G. D'Abrosca, M. Madheswaran, R. Benfante, S. Di Lascio, L. Caldinelli, D. Fornasari, C. Acconcia, A. Corvino, N. Ventserova, L. Pollegioni, C. Isernia, S. Di Gaetano, G. Malgieri, E.M. Pedone, R. Fattorusso
The Human-Restricted Isoform of the α7 nAChR, CHRFAM7A: A Double-Edged Sword in Neurological and Inflammatory Disorders
2022 S. Di Lascio, D. Fornasari, R. Benfante
Etonogestrel Administration Reduces the Expression of PHOX2B and Its Target Genes in the Solitary Tract Nucleus
2022 S. Cardani, T.A. Janes, J.K. Saini, S. Di Lascio, R. Benfante, D. Fornasari, S. Pagliardini
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9- nicotinic ligands on glioblastoma cells
2022 S. Pucci, C. Bolchi, F. Bavo, M. Pallavicini, C. De Palma, M. Renzi, S. Fucile, R. Benfante, S. Di Lascio, D. Lattuada, J. Bessereau, M. D'Alessandro, V. Risson, M. Zoli, F. Clementi, C. Gotti
Generation of two hiPSC lines (UMILi027-A and UMILi028-A) from early and late-onset Congenital Central hypoventilation Syndrome (CCHS) patients carrying a polyalanine expansion mutation in the PHOX2B gene
2022 A.L. Cuadros Gamboa, R. Benfante, M. Nizzardo, T. Bachetti, P. Pelucchi, V. Melzi, C. Arzilli, M. Peruzzi, R.A. Reinbold, S. Cardani, A. Morrone, R. Guerrini, I. Zucchi, S. Corti, I. Ceccherini, R. Piumelli, N. Nassi, S. Di Lascio, D. Fornasari
Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors
2021 S. Pucci, F. Fasoli, M. Moretti, R. Benfante, S. Di Lascio, P. Viani, A. Daga, T.J. Gordon, M. Mcintosh, M. Zoli, F. Clementi, C. Gotti
Research Advances on Therapeutic Approaches to Congenital Central Hypoventilation Syndrome (CCHS)
2021 S. Di Lascio, R. Benfante, S. Cardani, D. Fornasari
Acetyl-L-carnitine in chronic pain: A narrative review
2021 P. Sarzi-Puttini, V. Giorgi, S. Di Lascio, D. Fornasari
Effect of donepezil on the expression and responsiveness to LPS of CHRNA7 and CHRFAM7A in macrophages : a possible link to the cholinergic anti-inflammatory pathway
2019 A. Maroli, S. Di Lascio, L. Drufuca, S. Cardani, E. Setten, M. Locati, D. Fornasari, R. Benfante
Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation
2019 L. Pirone, L. Caldinelli, S. Di Lascio, R. Di Girolamo, S. Di Gaetano, D. Fornasari, L. Pollegioni, R. Benfante, E. Pedone