DI LASCIO, SIMONA
DI LASCIO, SIMONA
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
Generation of patient-specific, iPSC-derived brainstem organoids to study Congenital Central Hypoventilation Syndrome (CCHS)
2026 F. Chiesa, S. Di Lascio, A.L. Cuadros Gamboa, A. Chiodi, E. Mosca, M. Bertocchi, A. Ripepi, R. Benfante, E. Piscitelli, D. Fornasari
A MULTIMODAL APPROACH TO UNDERSTANDING BRAIN ORGANOIDS MATURATION OVER TIME
2026 F. Chiesa, A. Chiodi, V. Alcolea-Rodriguez, M. Bonanomi, C. Cocola, P. Pelucchi, C. Agrimi, E. Mosca, S. Di Lascio, D. Gaglio, D. Fornasari, R. Vanna, E. Piscitelli
IPSC-DERIVED SYMPATHETIC NEURONS AS A MODEL FOR STUDYING THE ROLE OF PHOX2B IN CONGENITAL CENTRAL HYPOVENTILATION SYNDROME
2026 M. Bertocchi, S. Di Lascio, A.L. Cuadros Gamboa, F. Chiesa, A. Ripepi, E. Donà, E. Mosca, P. Pelucchi, R. Benfante, D. Fornasari
Regulation of PHOX2B gene expression by the long non-coding natural antisense RNA PHOX2B-AS1
2026 S. Di Lascio, A.L. Cuadros Gamboa, M. Bertocchi, F. Chiesa, F. Cargnin, E. Mosca, P. Pelucchi, V. Tritto, S. Corti, I. Ceccherini, P. Riva, R. Benfante, D. Fornasari
Generation of iPSC lines (UMILi032-A, UMILi033-A, UMILi034-A, UMILi035-A, UMILi036-A) from five Congenital Central Hypoventilation Syndrome patients carrying different poly-alanine expansion mutations in the PHOX2B gene
2026 A.L. Cuadros Gamboa, F. Chiesa, P. Pelucchi, M. Bertocchi, A. Ripepi, E. Piscitelli, M. Peruzzi, N. Nassi, C. Arzilli, M. Annunziata, A. Morrone, V. Tritto, P. Riva, G. Santamaria, I. Ceccherini, R. Benfante, S. Di Lascio, D. Fornasari
CRISPR/Cas9-mediated PHOX2B functional knock-out in IMR32 neuroblastoma cells impairs neuronal excitability through dysregulation of ion channels genes
2026 S. Cardani, M. Bertocchi, E. Donà, F. Chiesa, C. Cambria, A.L. Cuadros Gamboa, E. Piscitelli, V. Rancic, S. Gosgnach, S. Pagliardini, F. Antonucci, D. Fornasari, S. Di Lascio, R. Benfante
Study of the function of the natural antisense lncRNA PHOX2B-AS1 in 2D and 3D iPSc derived neuronal models of Congenital Central Hypoventilation Syndrome
2025 S. Di Lascio, E. Piscitelli, A. Lucia Cuadros Gamboa, M. Bertocchi, F. Chiesa, A. Chiodi, E. Mosca, P. Pelucchi, R. Benfante, D. Fornasari
Leveraging Brain Organoids to Explore Neurodevelopmental Mechanisms in Congenital Central Hypoventilation Syndrome (CCHS)
2025 E. Piscitelli, S. Di Lascio, F. Chiesa, A. Chiodi, C. Cocola, P. Pelucchi, D. Gaglio, M. Bonanomi, R. Vanna, V. Alcolea Rodriguez, A. Lucia Cuadros Gamboa, M. Bertocchi, D. Fornasari, R. Benfante
The natural antisense lncRNA PHOX2B-AS1 in the pathogenesis and as potential drug target in Congenital Central Hypoventilation Syndrome (CCHS)
2025 R. Benfante, A.L. Cuadros Gamboa, M. Bertocchi, F. Chiesa, S. Di Lascio, D. Fornasari
Leveraging Brain Organoids to Explore Congenital Central Hypoventilation Syndrome (CCHS)
2025 F. Chiesa, M. Bertocchi, A.L. Cuadros Gamboa, P. Pelucchi, R. Benfante, S. Di Lascio, E. Piscitelli, D. Fornasari
Expression Deregulation of lncRNA PHOX2B-AS1 in the Pathogenesis of CCHS
2025 S. Di Lascio, E. Piscitelli, M. Bertocchi, F. Chiesa, A. Lucia Cuadros Gamboa, E. Mosca, P. Pelucchi, A. Chiodi, R. Benfante, D. Fornasari
Generation of 2D and 3D iPSC-derived neuronal models for the study of Congenital Central Hypoventilation Syndrome (CCHS)
2024 A.L. Cuadros Gamboa, E. Piscitelli, M. Bertocchi, F. Chiesa, P. Pelucchi, S. Di Lascio, R. Benfante, D. Fornasari
2D and 3D iPSC-derived neuronal models for the study of the role of lncRNA PHOX2B-AS1 in the pathogenesis of Congenital Central Hypoventilation Syndrome
2024 M. Bertocchi, S. Di Lascio, A.L. Cuadros, F. Chiesa, E. Piscitelli, P. Pelucchi, D. Fornasari, R. Benfante
Inflammatory or non-inflammatory pain in inflammatory arthritis – How to differentiate it?
2024 P. Sarzi-Puttini, G. Pellegrino, V. Giorgi, S.F. Bongiovanni, G. Varrassi, S. Di Lascio, D. Fornasari, S. Sirotti, M. Di Carlo, F. Salaffi
iPSC-derived autonomic neurons for the study of the role of lncRNA PHOX2B-AS1 in the pathogenesis of Congenital Central Hypoventilation Syndrome
2024 M. Bertocchi, S. Di Lascio, A.L. Cuadros, F. Chiesa, E. Piscitelli, P. Pelucchi, R. Benfante, D. Fornasari
Pharmacotherapeutic advances in fibromyalgia: what’s new on the horizon?
2024 P. Sarzi-Puttini, V. Giorgi, S. Sirotti, L. Bazzichi, D. Lucini, S. Di Lascio, G. Pellegrino, D. Fornasari
Study of the role of lncRNA PHOX2B-AS1 in the pathogenesis of Congenital Central Hypoventilation Syndrome
2024 M. Bertocchi, A.L. Cuadros Gamboa, F. Chiesa, R. Benfante, D. Fornasari, S. Di Lascio
Structural characterization of PHOX2B and its DNA interaction shed light on the molecular basis of the +7Ala variant pathogenicity in CCHS
2024 D. Diana, L. Pirone, L. Russo, G. D'Abrosca, M. Madheswaran, R. Benfante, S. Di Lascio, L. Caldinelli, D. Fornasari, C. Acconcia, A. Corvino, N. Ventserova, L. Pollegioni, C. Isernia, S. Di Gaetano, G. Malgieri, E.M. Pedone, R. Fattorusso
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9- nicotinic ligands on glioblastoma cells
2022 S. Pucci, C. Bolchi, F. Bavo, M. Pallavicini, C. De Palma, M. Renzi, S. Fucile, R. Benfante, S. Di Lascio, D. Lattuada, J. Bessereau, M. D'Alessandro, V. Risson, M. Zoli, F. Clementi, C. Gotti
Generation of two hiPSC lines (UMILi027-A and UMILi028-A) from early and late-onset Congenital Central hypoventilation Syndrome (CCHS) patients carrying a polyalanine expansion mutation in the PHOX2B gene
2022 A.L. Cuadros Gamboa, R. Benfante, M. Nizzardo, T. Bachetti, P. Pelucchi, V. Melzi, C. Arzilli, M. Peruzzi, R.A. Reinbold, S. Cardani, A. Morrone, R. Guerrini, I. Zucchi, S. Corti, I. Ceccherini, R. Piumelli, N. Nassi, S. Di Lascio, D. Fornasari