GRAZIOSO, GIOVANNI
GRAZIOSO, GIOVANNI
Dipartimento di Scienze Farmaceutiche
Ago-allosteric modulation of nicotinic alpha7 receptors : a mechanistic insight by metadynamics and essential dynamics
2014-06-11 G. Grazioso
Agonisti nicotinici selettivi nel trattamento di patologie del Sistema Nervoso Centrale
2007-09-16 C. De Micheli, M. De Amici, C. Dallanoce, G. Grazioso, L. Rizzi, P. Magrone, C. Matera
Analytical, computational and formulation studies on TPGS as P-gp inhibitor
2015-11-01 M.D. Del Curto, C. Bolchi, A. Foppoli, L. Fumagalli, F. Selmin, G. Grazioso, L. Palugan
Application of the Ugi reaction with multiple amino acid-derived components : synthesis and conformational evaluation of piperazine-based minimalist peptidomimetics
2015-04-22 M. Stucchi, S. Cairati, R. Cetin Atalay, M. Christodoulou, G. Grazioso, G. Pescitelli, A. Silvani, D.C. Yildirim, G. Lesma
Biological Characterization of Computationally Designed Analogs of peptide TVFTSWEEYLDWV (Pep2-8) with Increased PCSK9 Antagonistic Activity
2019-02-20 C. Lammi, J. Sgrignani, A. Arnoldi, G. Grazioso
Computational Design and Biological Evaluation of Analogs of Lupin Peptide P5 Endowed with Dual PCSK9/HMG-CoAR Inhibiting Activity
2022-03-18 C. Lammi, E. Fassi, J. Li, M. Bartolomei, G. Benigno, G. Roda, A. Arnoldi, G. Grazioso
COMPUTATIONAL INVESTIGATION ON SUBSTRATE UPTAKE AND RELEASE IN A GLUTAMATE TRANSPORTER
2012-04-17 G. Grazioso, V. Limongelli, D. Branduardi, E. Novellino, C. De Micheli, A. Cavalli, M. Parrinello
Covalent docking of selected boron-based serine beta-lactamase inhibitors
2015-05-01 J. Sgrignani, B. Novati, G. Colombo, G. Grazioso
Design and synthesis of selective ligands targeting different nAChR subtypes
2014-02-27 M. Quadri, C. Matera, G. Grazioso, M. De Amici, C. Dallanoce
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF PEPTIDOMIMETIC FALCIPAIN-2 INHIBITORS AS ANTIMALARIAL AGENTS
2012-04-17 N. Micale, R. Ettari, T. Schirmeister, G. Grazioso, S. Grasso, M. Zappalà
Determination of acid dissociation constants of compounds active at neuronal nicotinic acetylcholine receptors by means of electrophoretic and potentiometric techniques
2010-01-01 G. Roda, C. Dallanoce, G. Grazioso, V. Liberti, M. De Amici
Determination of acid dissociation constants of poorly water-soluble nicotinic ligands by means of electrophoretic and potentiometric techniques
2015-07-20 G. Roda, C. Dallanoce, V. Gambaro, G. Grazioso, V. Liberti, C. Matera, M. Quadri, M. De Amici
Determinazione dell’energia di legame di agonisti del recettore nicotinico alpha-7 mediante applicazione dell’approccio MMPB(GB)SA
2007-01-01 G. Grazioso, A. Cavalli, M. Recanatini, M. De Amici, C. De Micheli
Diazabicyclo analogues of maraviroc : synthesis, modeling, NMR studies and antiviral activity
2017-02-01 L. Legnani, D. Colombo, A. Venuti, C. Pastori, L. Lopalco, L. Toma, M. Mori, G. Grazioso, S. Villa
Evaluation of binding free Energy of nicotinic agonists by the linear interaction energy (LIE) approach
2008-01-01 G. Grazioso, Y.D. Pomè, C. Dallanoce, M. De Amici, C. De Micheli
Exploring Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Autoproteolysis Process by Molecular Simulations: Hints for Drug Design
2020-01-01 J. Sgrignani, E.M.A. Fassi, C. Lammi, G. Roda, G. Grazioso
First Food-Derived Peptide Inhibitor of the Protein-Protein Interaction between Gain-of-Function PCSK9D374Y and the Low-Density Lipoprotein Receptor
2018-10-10 G. Grazioso, C. Bollati, S. Jacopo, A. Arnoldi, C. Lammi
Focused Design of Novel Cyclic Peptides Endowed with GABARAP-Inhibiting Activity
2022-05-03 E.M.A. Fassi, M. Garofalo, J. Sgrignani, M.V. DEI CAS, M. Mori, G. Roda, A. Cavalli, G. Grazioso
(-)-HIP-A and (+)-HIP-B: investigation of the pharmacological profile and potential therapeutic applications
2007-06-01 P. Conti, A. Pinto, L. Tamborini, G. Grazioso, S. Colleoni, M. Gobbi, T. Mennini
How computational chemistry and drug delivery techniques can support the development of new anticancer drugs
2020-04-10 M. Garofalo, G. Grazioso, A. Cavalli, J. Sgrignani