GRAZIOSO, GIOVANNI
GRAZIOSO, GIOVANNI
Dipartimento di Scienze Farmaceutiche
Computationally Driven Structure Optimization, Synthesis, and Biological Evaluation of Imidazole-Based Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Inhibitors
2019 C. Lammi, J. Sgrignani, A. Arnoldi, G. Lesma, C. Spatti, A. Silvani, G. Grazioso
Biological Characterization of Computationally Designed Analogs of peptide TVFTSWEEYLDWV (Pep2-8) with Increased PCSK9 Antagonistic Activity
2019 C. Lammi, J. Sgrignani, A. Arnoldi, G. Grazioso
Oxidation State Dependent Conformational Changes of HMGB1 Regulate the Formation of the CXCL12/HMGB1 Heterocomplex
2019 E.M.A. Fassi, J. Sgrignani, G. D'Agostino, V. Cecchinato, M. Garofalo, G. Grazioso, M. Uguccioni, A. Cavalli
Inhibition of PCSK9D374Y/LDLR Protein–Protein Interaction by Computationally Designed T9 Lupin Peptide
2019 C. Lammi, J. Sgrignani, G. Roda, A. Arnoldi, G. Grazioso
Structure-based drug design, synthesis and biological assays of P. falciparum Atg3-Atg8 protein-protein interaction inhibitors
2018 S. Villa, L. Legnani, D. Colombo, A. Gelain, C. Lammi, D. Bongiorno, D.P. Ilboudo, K.E. Mcgee, J. Bosch, G. Grazioso
Disrupting the PCSK9/LDLR protein-protein interaction by an imidazole-based minimalist peptidomimetic
2016 M. Stucchi, G. Grazioso, C. Lammi, S. Manara, C. Zanoni, A. Arnoldi, G. Lesma, A. Silvani
Lupin peptides modulate the protein-protein interaction of PCSK9 with the low density lipoprotein receptor in HepG2 cells
2016 C. Lammi, C. Zanoni, G. Aiello, A. Arnoldi, G. Grazioso
Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors
2016 J. Sgrignani, F. de Luca, H. Torosyan, J. Docquier, D. Duan, B. Novati, F. Prati, G. Colombo, G. Grazioso
Allosteric modulation of alpha7 nicotinic receptors : mechanistic insight through metadynamics and essential dynamics
2015 G. Grazioso, J. Sgrignani, R. Capelli, C. Matera, C. Dallanoce, M. De Amici, A. Cavalli
Covalent docking of selected boron-based serine beta-lactamase inhibitors
2015 J. Sgrignani, B. Novati, G. Colombo, G. Grazioso