POME', DIEGO YURI
POME', DIEGO YURI
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
DESIGN, SYNTHETIC APPROACHES, BIOPHARMACOLOGICAL INVESTIGATION, AND STRUCTURE ACTIVITY RELATIONSHIPS OF NOVEL LIGANDS TARGETING NEURONAL NICOTINIC RECEPTOR SUBTYPES
2013 D.Y. Pome'
Evaluation of binding free energy of nicotinic agonists by the linear ineraction energy (LIE) approach
2008 G. Grazioso, Y.D. Pomè, C. Dallanoce, M. De Amici, C. De Micheli
Evaluation of binding free Energy of nicotinic agonists by the linear interaction energy (LIE) approach
2008 G. Grazioso, Y.D. Pomè, C. Dallanoce, M. De Amici, C. De Micheli
Gangliosides in the differentiation process of primary neurons: the specific role of GM1-oligosaccharide
2020 E. Di Biase, G. Lunghi, M. Fazzari, M. Maggioni, D.Y. Pomè, M. Valsecchi, M. Samarani, P. Fato, M.G. Ciampa, S. Prioni, L. Mauri, S. Sonnino, E. Chiricozzi
GM1 neurotrophic properties are related to GM1 oligosaccharide - TRKA interaction.
2017 M. Maggioni, E. Chiricozzi, D..Y. Pome', E. Di Biase, M. Aureli, S. Sonnino
GM1 neurotrophic properties are related to gm1oligosaccharide - TrkA interaction in mouse neuroblastoma cells
2017 E. Chiricozzi, D..Y. Pome', M. Maggioni, E. Di Biase, C. Parravicini, I. Eberini, S. Sonnino
GM1 Oligosaccharide Crosses the Human Blood-Brain Barrier In Vitro by a Paracellular Route
2020 E. Di Biase, G. Lunghi, M. Maggioni, M. Fazzari, D.Y. Pomè, N. Loberto, M.G. Ciampa, P. Fato, L. Mauri, E. Sevin, F. Gosselet, S. Sonnino, E. Chiricozzi
GM1 promotes TrkA-mediated neuroblastoma cell differentiation by occupying a plasma membrane domain different from TrkA
2019 E. Chiricozzi, E.D. Biase, M. Maggioni, G. Lunghi, M. Fazzari, D.Y. Pomè, R. Casellato, N. Loberto, L. Mauri, S. Sonnino
In silico design of agonists targeting the alpha7 nicotinic acetylcholine receptors, their synthesis and preliminary pharmacological evaluation
2009 C. Matera, D.Y. Pomè, L. Pucci, C. Gotti, C.M.L. Dallanoce, G. Grazioso, M. De Amici
Metadynamic investigations of the aspartate binding at glutamate transporters
2009 G. Grazioso, Y.D. Pomè, V. Limongelli, D. Branduardi, A. Cavalli, C. De Micheli, M. Parrinello
Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype [Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the alpha 3 beta 4 nicotinic acetylcholine receptor subtype]
2016 C. Matera, M. Quadri, M. Sciaccaluga, D.Y. Pomè, F. Fasoli, M. De Amici, S. Fucile, C. Gotti, C. Dallanoce, G. Grazioso
Novel ligands for neuronal nicotinic receptor subtypes: synthetic, pharmacological and molecular docking studies
2012 C. Matera, D.Y. Pomè, C.M.L. Dallanoce, G. Grazioso, L. Pucci, S. Fucile, C. Gotti, F. Clementi, M. De Amici
Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes
2010 C.M.L. Dallanoce, F. Frigerio, G. Martelli, G. Grazioso, C. Matera, D.Y. Pome', L. Pucci, F. Clementi, C. Gotti, M. DE AMICI
Parkinson's disease recovery by GM1 oligosaccharide treatment in the B4galnt1+/- mouse model
2019 E. Chiricozzi, L. Mauri, G. Lunghi, E. Di Biase, M. Fazzari, M. Maggioni, M. Valsecchi, S. Prioni, N. Loberto, D.Y. Pomè, M.G. Ciampa, P. Fato, G. Verlengia, S. Cattaneo, R. Assini, G. Wu, S. Alselehdar, R.W. Ledeen, S. Sonnino
Role of the GM1 ganglioside oligosaccharide portion in the TrkA-dependent neurite sprouting in neuroblastoma cells
2017 E. Chiricozzi, D. Pomè, M. Maggioni, E. Di Biase, C. Parravicini, L. Palazzolo, N. Loberto, I. Eberini, S. Sonnino
Study of the neurodifferentiative role of GM1 oligosaccharide chain in mouse primary cerebellar neurons
2017 E. Di Biase, E. Chiricozzi, M. Maggioni, D..Y. Pome', M. Samarani, S. Prioni, M. Aureli, S. Sonnino
The Neurotrophic properties of GM1 oligosaccharide: a new promising story
2017 E. Chiricozzi, D.Y. Pomè, M. Maggioni, E. Di Biase, C. Parravicini, I. Eberini, S. Sonnino