MARANGON, DAVIDE
MARANGON, DAVIDE
Dipartimento di Scienze Farmaceutiche
Characterisation of GPR17-expressing oligodendrocyte precursors in human ischaemic lesions and correlation with reactive glial responses
2025 S. Raffaele, B.H. Clausen, F.C. Mannella, M. Wirenfeldt, D. Marangon, S.B. Tidgen, S. Corradini, K. Madsen, D. Lecca, M.P. Abbracchio, K.L. Lambertsen, M. Fumagalli
Exosomal non-coding RNAs in glioma progression: insights into tumor microenvironment dynamics and therapeutic implications
2023 D. Marangon, D. Lecca
G protein-coupled receptor 17 is regulated by WNT pathway during oligodendrocyte precursor cell differentiation
2023 M. Boccazzi, G. Macchiarulo, S. Lebon, J. Janowska, T. Le Charpentier, V. Faivre, J. Hua, D. Marangon, D. Lecca, M. Fumagalli, S. Mani, M.P. Abbracchio, P. Gressens, A. Schang, J. Van Steenwinckel
Neuronal and Glial Communication via Non-Coding RNAs: Messages in Extracellular Vesicles
2023 D. Marangon, J.H. Castro E Silva, D. Lecca
Rewiring of Glucose and Lipid Metabolism Induced by G Protein-Coupled Receptor 17 Silencing Enables the Transition of Oligodendrocyte Progenitors to Myelinating Cells
2022 D. Marangon, M. Audano, S. Pedretti, M. Fumagalli, N. Mitro, D. Lecca, D. Caruso, M.P. Abbracchio
Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis
2022 M.S. Paladini, D. Marangon, A.C. Rossetti, A. Guidi, G.T. Coppolino, C. Negri, V. Spero, M.P. Abbracchio, D. Lecca, R. Molteni
The Distribution of GPR17-Expressing Cells Correlates with White Matter Inflammation Status in Brain Tissues of Multiple Sclerosis Patients
2021 J. Angelini, D. Marangon, S. Raffaele, D. Lecca, M.P. Abbracchio
Novel in vitro experimental approaches to study myelination and remyelination in the central nervous system
2021 D. Marangon, N. Caporale, M. Boccazzi, M.P. Abbracchio, G. Testa, D. Lecca
Pathway-Focused Profiling of Oligodendrocytes Over-Expressing miR-125a-3p Reveals Alteration of Wnt and Cell-to-Cell Signaling
2021 D. Marangon, M.P. Abbracchio, D. Lecca
Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis
2020 C. Parravicini, D. Lecca, D. Marangon, G.T. Coppolino, S. Daniele, E. Bonfanti, M. Fumagalli, L. Raveglia, C. Martini, E. Gianazza, M.L. Trincavelli, M.P. Abbracchio, I. Eberini
Regulation of oligodendrocyte functions : targeting lipid metabolism and extracellular matrix for myelin repair
2020 D. Marangon, M. Boccazzi, D. Lecca, M. Fumagalli
In vivo silencing of miR-125a-3p promotes myelin repair in models of white matter demyelination
2020 D. Marangon, E. Boda, R. Parolisi, C. Negri, C. Giorgi, F. Montarolo, S. Perga, A. Bertolotto, A. Buffo, M.P. Abbracchio, D. Lecca
MicroRNAs change the games in central nervous system pharmacology
2019 D. Marangon, S. Raffaele, M. Fumagalli, D. Lecca
Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination
2018 G.T. Coppolino, D. Marangon, C. Negri, G. Menichetti, M. Fumagalli, P. Gelosa, L. Dimou, R. Furlan, D. Lecca, M.P. Abbracchio
MICRORNA-125A-3P NEGATIVELY REGULATES OLIGODENDROGLIAL MATURATION AND RE-MYELINATION: MOLECULAR MECHANISMS AND CLINICAL IMPLICATIONS
2018 D. Marangon
The genetic inhibition of GPR17 affects myelination by influencing important players in oligodendrocyte maturation, including purinergic receptors
2017 D. Lecca, D. Marangon, G. Coppolino, E. Bonfanti, M. Fumagalli, M. Abbracchio
GPR17-expressing oligodendrocyte precursor cells differentially react to damage in experimental autoimmune encephalomyelitis and cuprizone-induced demyelination
2017 D. Marangon, G. Coppolino, D. Lecca, F. Viganò, M. Fumagalli, R. Furlan, L. Dimou, M. Abbracchio
Dysregulation of the GPR17 receptor in neuroinflammatory diseases: implications for remyelination in multiple sclerosis
2017 D. Lecca, G.T. Coppolino, D. Marangon, M. Fumagalli, C. Parravicini, R. Magliozzi, L. Dimou, R. Furlan, M..P. Abbracchio
Local dysregulation of the GPR17 receptor in neuroinflammatory diseases: implications for remyelination in multiple sclerosis
2017 D. Lecca, G. Coppolino, D. Marangon, L. Dimou, R. Furlan, M. Abbracchio
Mir-125a-3p negatively regulates oligodendrocyte precursor cells maturation and is altered in human multiple sclerosis
2017 D. Marangon, E. Boda, C. Giorgi, G.T. Coppolino, R. Parolisi, A. Finardi, R. Furlan, A. Buffo, M.P. Abbracchio, D. Lecca