ABBRACCHIO, MARIA PIA
ABBRACCHIO, MARIA PIA
Dipartimento di Scienze Farmaceutiche
Selective targeting of the oligodendroglial GPR17 receptor improves myelin integrity and motor function in female SOD1G93A mice
2026 S. Raffaele, T. Bonifacino, F.C. Mannella, N. Nguyen, C. Torazza, D. Marangon, E. Chinosi, H.D. Schrøder, E.K. Hejbøl, K. Madsen, L. Marchetti, M.L. Trincavelli, M. Milanese, D. Lecca, K.L. Lambertsen, G. Bonanno, M.P. Abbracchio, M. Fumagalli
The GPR17 agonist galinex restores oligodendrocyte maturation under inflammatory conditions
2026 J.H. Castro E Silva, D. Marangon, M. Boccazzi, S. Raffaele, N. Cignitti, M. Bavetta, I. Arisi, M. Fumagalli, M.P. Abbracchio, D. Lecca
Arugula leaf nanovesicles as sustainable food ingredient: processing, stability, and bioavailability
2026 L. D’Adduzio, D. Marangon, U. Musazzi, G. Frigerio, G. Ranaldi, B. Lazzari, L. Sironi, R. Pugliese, M.P. Abbracchio, D. Lecca, C. Lammi
Microglia-Derived Extracellular Vesicles Enhance Oligodendrocyte Maturation by Transcriptionally Regulating Mitochondrial Molecular Pathways
2025 S. Raffaele, M. Lombardi, D. Marangon, M.P. Abbracchio, D. Lecca, C. Verderio, M. Fumagalli
The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors
2025 S.P.H. Alexander, A.P. Davenport, E. Kelly, A.J. Gibb, A.A. Mathie, C.J. Peach, E.L. Veale, J.F. Armstrong, E. Faccenda, S.D. Harding, C. Southan, J.A. Davies, M.P. Abbracchio, G.R. Abraham, A. Agoulnik, W. Alexander, K. Al-Hosaini, M. Bäck, J.G. Baker, N.M. Barnes, R. Bathgate, J. Beaulieu, A.G. Beck-Sickinger, M. Behrens, K.A. Bennett, K.E. Bernstein, B. Bettler, N.J.M. Birdsall, V.A. Blaho, P. Bonaventure, F. Boulay, C. Bousquet, H. Bräuner-Osborne, A.J. Brown, G. Burnstock, M. Busnelli, G. Caló, V. Caruso, J.P. Castaño, K.J. Catt, S. Ceruti, P. Chazot, N. Chiang, B. Chini, A. Christopoulos, J. Chun, A. Cianciulli, O. Civelli, L.H. Clapp, R. Couture, H.M. Cox, Z. Csaba, C. Dahlgren, F.M. Dautzenberg, G. Dent, S.D. Douglas, P. Dournaud, M.L. Dubocovich, S. Eguchi, E. Escher, E.J. Filardo, T. Fong, H.F. Forsman, M. Fumagalli, R.R. Gainetdinov, M.L. Garelja, M. De Gasparo, F. Gbahou, C. Gerard, M. Gershengorn, M. Glass, D.E. Gloriam, F. Gobeil, T.L. Goodfriend, C. Goudet, L. Grätz, K.J. Gregory, C. Gruber, A.L. Gundlach, J. Hamann, J. Hanson, D.S. Hartman, R.L. Hauger, D.L. Hay, A. Heinemann, L. Heitman, D.R. Herr, M.D. Hollenberg, N.D. Holliday, B. Holst, M. Horiuchi, D. Hoyer, L. Hunyady, A. Husain, A.P. Ijzerman, T. Inagami, P.A. Insel, K.A. Jacobson, L.H. Jacobson, R.T. Jensen, R. Jockers, D. Jonnalagadda, S. Karnik, K. Kaupmann, J. Kemp, C. Kennedy, Y. Kihara, J. Kinsolving, T. Kitazawa, P. Kozielewicz, H. Kreienkamp, J.P. Kukkonen, L. Laishram, T. Langenhan, C.J. Langmead, D. Larhammar, K. Leach, D. Lecca, J.D. Lee, S.E. Leeman, J. Leprince, R. Leurs, X.X. Li, I. Liebscher, S.J. Lolait, A. Lupp, R. Macrae, J.J. Maguire, D. Malfacini, M. Manning, D. Marangon, K. Martemyanov, J. Mazella, C.A. Mcardle, S. Melmed, M.C. Michel, L.J. Miller, V. Mitolo, B. Mouillac, C.E. Müller, P.M. Murphy, J. Nahon, R.R. Neubig, T. Ngo, X. Norel, D. Nyimanu, A. O'Carroll, S. Offermanns, M.A. Panaro, M. Parmentier, N. Perry-Hauser, R.G. Pertwee, J. Pin, E.R. Prossnitz, H.C. Qin, M. Quinn, S. Raffaele, R. Ramachandran, M. Ray, R.K. Reinscheid, A.R. Buzón, P. Rondard, M.M. Rosenkilde, G.E. Rovati, C. Ruzza, G.J. Sanger, N. Scholz, T. Schöneberg, G. Schulte, S. Schulz, D.L. Segaloff, C.N. Serhan, A.K. Shukla, K.D. Singh, C.M. Smith, N.J. Smith, C. Stäubert, L.A. Stoddart, Y. Sugimoto, R. Summers, V.P. Tan, D.M. Thal, W.W. Thomas, P.B.M.W.M. Timmermans, K. Tirupula, L. Toll, G. Tulipano, H. Unal, T. Unger, C. Valant, P. Vanderheyden, D. Vaudry, H. Vaudry, J.G. Verbalis, J. Vilardaga, C.S. Walker, J.M. Wang, D.T. Ward, H. Wester, G.B. Willars, T.L. Williams, T.M. Woodruff, H. Wu, C. Yang, C. Yao, R.D. Ye, N. Zaidman
From gender equality research to gender medicine: Where do we stand? Reflections from the Department of biomedical, surgical and dental sciences, University of Milan
2025 G. Ottaviani, M.P. Abbracchio
Characterisation of GPR17-expressing oligodendrocyte precursors in human ischaemic lesions and correlation with reactive glial responses
2025 S. Raffaele, B.H. Clausen, F.C. Mannella, M. Wirenfeldt, D. Marangon, S.B. Tidgen, S. Corradini, K. Madsen, D. Lecca, M.P. Abbracchio, K.L. Lambertsen, M. Fumagalli
Montelukast improves disease outcome in SOD1G93A female mice by counteracting oligodendrocyte dysfunction and aberrant glial reactivity
2024 S. Raffaele, N. Nguyen, M. Milanese, F.C. Mannella, M. Boccazzi, G. Frumento, G. Bonanno, M.P. Abbracchio, T. Bonifacino, M. Fumagalli
Neurodegeneration after brain ischemia in aged mice: beneficial effects of Montelukast
2024 M. Muluhie, S. Raffaele, P. Gelosa, L. Castiglioni, B. Mercuriali, J. Rzemieniec, D. Lecca, M.P. Abbracchio, M. Fumagalli, L. Sironi
Oligodendrocytes are key players in the montelukast-induced protection against stroke
2023 M. Muluhie, B. Mercuriali, J.H. Castro E Silva, L. Castiglioni, P. Gelosa, J.M. Delgado-Garcia, A. Gruart, D. Lecca, M. Cimino, J. Rzemieniec, M.P. Abbracchio, L. Sironi
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
2023 S.P.H. Alexander, A. Christopoulos, A.P. Davenport, E. Kelly, A.A. Mathie, J.A. Peters, E.L. Veale, J.F. Armstrong, E. Faccenda, S.D. Harding, J.A. Davies, M.P. Abbracchio, G. Abraham, A. Agoulnik, W. Alexander, K. Al‐hosaini, M. Bäck, J.G. Baker, N.M. Barnes, R. Bathgate, J. Beaulieu, A.G. Beck‐sickinger, M. Behrens, K.E. Bernstein, B. Bettler, N.J.M. Birdsall, V. Blaho, F. Boulay, C. Bousquet, H. Bräuner‐osborne, G. Burnstock, G. Caló, J.P. Castaño, K.J. Catt, S. Ceruti, P. Chazot, N. Chiang, B. Chini, J. Chun, A. Cianciulli, O. Civelli, L.H. Clapp, R. Couture, H.M. Cox, Z. Csaba, C. Dahlgren, G. Dent, S.D. Douglas, P. Dournaud, S. Eguchi, E. Escher, E.J. Filardo, T. Fong, M. Fumagalli, R.R. Gainetdinov, M.L. Garelja, M. de Gasparo, C. Gerard, M. Gershengorn, F. Gobeil, T.L. Goodfriend, C. Goudet, L. Grätz, K.J. Gregory, A.L. Gundlach, J. Hamann, J. Hanson, R.L. Hauger, D.L. Hay, A. Heinemann, D. Herr, M.D. Hollenberg, N.D. Holliday, M. Horiuchi, D. Hoyer, L. Hunyady, A. Husain, A.P. Ijzerman, T. Inagami, K.A. Jacobson, R.T. Jensen, R. Jockers, D. Jonnalagadda, S. Karnik, K. Kaupmann, J. Kemp, C. Kennedy, Y. Kihara, T. Kitazawa, P. Kozielewicz, H. Kreienkamp, J.P. Kukkonen, T. Langenhan, D. Larhammar, K. Leach, D. Lecca, J.D. Lee, S.E. Leeman, J. Leprince, X.X. Li, S.J. Lolait, A. Lupp, R. Macrae, J. Maguire, D. Malfacini, J. Mazella, C.A. Mcardle, S. Melmed, M.C. Michel, L.J. Miller, V. Mitolo, B. Mouillac, C.E. Müller, P.M. Murphy, J. Nahon, T. Ngo, X. Norel, D. Nyimanu, A. O’Carroll, S. Offermanns, M.A. Panaro, M. Parmentier, R.G. Pertwee, J. Pin, E.R. Prossnitz, M. Quinn, R. Ramachandran, M. Ray, R.K. Reinscheid, P. Rondard, G.E. Rovati, C. Ruzza, G.J. Sanger, T. Schöneberg, G. Schulte, S. Schulz, D.L. Segaloff, C.N. Serhan, K.D. Singh, C.M. Smith, L.A. Stoddart, Y. Sugimoto, R. Summers, V.P. Tan, D. Thal, W.(.W. Thomas, P.B.M.W.M. Timmermans, K. Tirupula, L. Toll, G. Tulipano, H. Unal, T. Unger, C. Valant, P. Vanderheyden, D. Vaudry, H. Vaudry, J. Vilardaga, C.S. Walker, J.M. Wang, D.T. Ward, H. Wester, G.B. Willars, T.L. Williams, T.M. Woodruff, C. Yao, R.D. Ye
G protein-coupled receptor 17 is regulated by WNT pathway during oligodendrocyte precursor cell differentiation
2023 M. Boccazzi, G. Macchiarulo, S. Lebon, J. Janowska, T. Le Charpentier, V. Faivre, J. Hua, D. Marangon, D. Lecca, M. Fumagalli, S. Mani, M.P. Abbracchio, P. Gressens, A. Schang, J. Van Steenwinckel
Montelukast, a safe anti-asthmatic drug, protects against stroke by improving anti-oxidant defence of oligodendrocyte precursor cells
2023 M. Muluhie, J.H. Castro E Silva, B. Mercuriali, L. Castiglioni, P. Gelosa, J.M. Delgado-Garcia, A. Gruart, D. Lecca, M. Cimino, J. Rzemieniec, M.P. Abbracchio, L. Sironi
P2Y receptors in GtoPdb v.2023.1
2023 M.P. Abbracchio, J. Boeynaems, J.L. Boyer, G. Burnstock, S.M. Ceruti, M. Fumagalli, C. Gachet, R. Hills, R.G. Humphries, K. Inoue, K.A. Jacobson, C. Kennedy, B.F. King, D. Lecca, C.E. Müller, M. Teresa Miras-Portugal, V. Ralevic, G.A. Weisman
Functional Heterodimerization between the G Protein-Coupled Receptor GPR17 and the Chemokine Receptors 2 and 4: New Evidence
2023 S. Daniele, S. Saporiti, S. Capaldi, D. Pietrobono, L. Russo, U. Guerrini, T. Laurenzi, E. Ataie Kachoie, L. Palazzolo, V. Russo, M.P. Abbracchio, I. Eberini, M.L. Trincavelli
Altered Purinergic Signaling in Neurodevelopmental Disorders: Focus on P2 Receptors
2023 M. Boccazzi, S. Raffaele, T. Zanettin, M.P. Abbracchio, M. Fumagalli
Donne nella scienza : La lunga strada verso la parità
2023 M.E. D'Amico, M.P. Abbracchio
Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis
2022 M.S. Paladini, D. Marangon, A.C. Rossetti, A. Guidi, G.T. Coppolino, C. Negri, V. Spero, M.P. Abbracchio, D. Lecca, R. Molteni
Rewiring of Glucose and Lipid Metabolism Induced by G Protein-Coupled Receptor 17 Silencing Enables the Transition of Oligodendrocyte Progenitors to Myelinating Cells
2022 D. Marangon, M. Audano, S. Pedretti, M. Fumagalli, N. Mitro, D. Lecca, D. Caruso, M.P. Abbracchio
Functional genomic analyses highlight a shift in Gpr17-regulated cellular processes in oligodendrocyte progenitor cells and underlying myelin dysregulation in the aged mouse cerebrum
2021 A.D. Rivera, F. Pieropan, I. Chacon-De-La-Rocha, D. Lecca, M.P. Abbracchio, K. Azim, A.M. Butt