COPPOLINO, GIUSY TINDARA
COPPOLINO, GIUSY TINDARA
Dipartimento di Scienze Farmacologiche e Biomolecolari
Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis
2022 M.S. Paladini, D. Marangon, A.C. Rossetti, A. Guidi, G.T. Coppolino, C. Negri, V. Spero, M.P. Abbracchio, D. Lecca, R. Molteni
Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis
2020 C. Parravicini, D. Lecca, D. Marangon, G.T. Coppolino, S. Daniele, E. Bonfanti, M. Fumagalli, L. Raveglia, C. Martini, E. Gianazza, M.L. Trincavelli, M.P. Abbracchio, I. Eberini
Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination
2018 G.T. Coppolino, D. Marangon, C. Negri, G. Menichetti, M. Fumagalli, P. Gelosa, L. Dimou, R. Furlan, D. Lecca, M.P. Abbracchio
The genetic inhibition of GPR17 affects myelination by influencing important players in oligodendrocyte maturation, including purinergic receptors
2017 D. Lecca, D. Marangon, G. Coppolino, E. Bonfanti, M. Fumagalli, M. Abbracchio
GPR17-expressing oligodendrocyte precursor cells differentially react to damage in experimental autoimmune encephalomyelitis and cuprizone-induced demyelination
2017 D. Marangon, G. Coppolino, D. Lecca, F. Viganò, M. Fumagalli, R. Furlan, L. Dimou, M. Abbracchio
Local dysregulation of the GPR17 receptor in neuroinflammatory diseases: implications for remyelination in multiple sclerosis
2017 D. Lecca, G. Coppolino, D. Marangon, L. Dimou, R. Furlan, M. Abbracchio
DYSREGULATION OF THE GPR17 RECEPTOR IN NEURO-INFLAMMATORY DISEASES: IMPLICATIONS FOR RE-MYELINATION IN MULTIPLE SCLEROSIS
2017 G.T. Coppolino
Mir-125a-3p negatively regulates oligodendrocyte precursor cells maturation and is altered in human multiple sclerosis
2017 D. Marangon, E. Boda, C. Giorgi, G.T. Coppolino, R. Parolisi, A. Finardi, R. Furlan, A. Buffo, M.P. Abbracchio, D. Lecca
Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine
2017 M. Fumagalli, D. Lecca, G.T. Coppolino, C. Parravicini, M.P. Abbracchio
A new miRNA regulating oligodendrocyte maturation in physiology and disease
2016 D. Marangon, G.T. Coppolino, A. Finardi, R. Furlan, M.P. Abbracchio, D. Lecca
GPR17 molecular modelling: interactions with non-conventional pro-inflammatory ligands
2016 L. Palazzolo, C. Parravicini, S. Daniele, M.L. Trincavelli, C. Martini, P. Zaratin, R. Primi, G.T. Coppolino, E. Gianazza, M.P. Abbracchio, I. Eberini
GPR17, a key receptor involved in oligodendrogenesis: implications for re-myelination strategies
2016 G.T. Coppolino, D. Lecca, D. Marangon, F. Viganò, C. Parravicini, I. Eberini, R. Magliozzi, R. Furlan, L. Dimou, M.P. Abbracchio
A promiscuous recognition mechanism between GPR17 and SDF-1 : molecular insights
2016 C. Parravicini, S. Daniele, L. Palazzolo, M.L. Trincavelli, C. Martini, P. Zaratin, R. Primi, G. Coppolino, E. Gianazza, M.P. Abbracchio, I. Eberini
MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis
2016 D. Lecca, D. Marangon, G.T. Coppolino, A.M. Méndez, A. Finardi, G.D. Costa, V. Martinelli, R. Furlan, M.P. Abbracchio
New mechanisms regulating myelination in the central nervous system : the role of GPR17 and of a novel micro-RNA
2015 M.P. Abbracchio, M. Fumagalli, D. Marangon, G.T. Coppolino, E. Bonfanti, A. Finardi, D. Lecca, R. Furlan
Promoting re-myelination in MS via the GPR17 receptor, a new key actor in oligodendrogenesis
2014 M.P. Abbracchio, D. Lecca, G.T. Coppolino, D. Marangon, M. Fumagalli, E. Bonfanti, G. Menichetti, R. Furlan
Gene regulation of the receptor GPR17 in oligodendroglial cells: expression pattern and pathological alterations in a mouse model of multiple sclerosis
2013 D. Lecca, G. Coppolino, G. Menichetti, D. Marangon, E. Bonfanti, A. Fratangeli, M. Fumagalli, P. Rosa, M.P. Abbracchio
Dysregulation of GPR17, a key receptor involved in oligodendrocyte maturation, as a novel potential pathogenetic mechanism in demyelinating diseases
2013 M. Fumagalli, E. Bonfanti, D. Lecca, G.T. Coppolino, M.P. Abbracchio
Gene regulation of the P2Y-like receptor GPR17 in oligodendrocytes, and pathological alterations in a mouse model of multiple sclerosis
2013 D. Lecca, G. Coppolino, G. Menichetti, D. Marangon, E. Bonfanti, A. Fratangeli, M. Fumagalli, P. Rosa, M.P. Abbracchio
Extracellular purine and pyrimidine nucleotides as local extrinsic regulators of adult neural progenitor cells in the diseased CNS
2013 M.P. Abbracchio, M. Fumagalli, D. Lecca, E. Bonfanti, C. Parravicini, G.T. Coppolino, S. Daniele, M.L. Trincavelli, C. Martini