COPPOLINO, GIUSY TINDARA

COPPOLINO, GIUSY TINDARA  

Dipartimento di Scienze Farmacologiche e Biomolecolari  

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Titolo Data di pubblicazione Autori Tipo File Abstract
Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis 22-apr-2020 Parravicini C.Lecca D.Marangon D.Coppolino G. T.Daniele S.Bonfanti E.Fumagalli M.Martini C.Gianazza E.Abbracchio M. P.Eberini I. + Article (author) -
Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination 1-mag-2018 G. T. CoppolinoD. MarangonC. NegriM. FumagalliP. GelosaFURLAN, ROBERTOD. LeccaM. P. Abbracchio + Article (author) -
Dysregulation of GPR17, a key receptor involved in NG2 progenitor cells differentiation to mature oligodendrocytes, as a novel potential pathogenetic mechanism in demyelinating diseases 1-gen-2012 E. BonfantiM. FumagalliC. ParraviciniD. LeccaG. CoppolinoM.P. Abbracchio + Conference Object -
Dysregulation of GPR17, a key receptor involved in oligodendrocyte maturation, as a novel potential pathogenetic mechanism in demyelinating diseases 1-gen-2013 M. FumagalliE. BonfantiD. LeccaG.T. CoppolinoM.P. Abbracchio Article (author) -
DYSREGULATION OF THE GPR17 RECEPTOR IN NEURO-INFLAMMATORY DISEASES: IMPLICATIONS FOR RE-MYELINATION IN MULTIPLE SCLEROSIS 26-gen-2017 G.T. Coppolino Doctoral Thesis -
Expression pattern and distribution of the oligodendroglial receptor GPR17 in Experimental Autoimmune Encephalomyelitis, a mouse model of Multiple Sclerosis 1-gen-2013 G. CoppolinoD. LeccaM. FumagalliM. Abbracchio + Conference Object -
Extracellular purine and pyrimidine nucleotides as local extrinsic regulators of adult neural progenitor cells in the diseased CNS 1-mag-2013 M.P. AbbracchioM. FumagalliD. LeccaE. BonfantiC. ParraviciniG.T. Coppolino + Article (author) -
Gene regulation of the P2Y-like receptor GPR17 in oligodendrocytes, and pathological alterations in a mouse model of multiple sclerosis 1-gen-2013 D. LeccaG. CoppolinoD. MarangonE. BonfantiM. FumagalliM.P. Abbracchio + Conference Object -
Gene regulation of the receptor GPR17 in oligodendroglial cells: expression pattern and pathological alterations in a mouse model of multiple sclerosis 1-gen-2013 D. LeccaG. CoppolinoD. MarangonE. BonfantiM. FumagalliM.P. Abbracchio + Conference Object -
The genetic inhibition of GPR17 affects myelination by influencing important players in oligodendrocyte maturation, including purinergic receptors 1-dic-2017 Lecca DMarangon DCoppolino GTBonfanti EFumagalli MAbbracchio MP. Article (author) -
GPR17 molecular modelling: interactions with non-conventional pro-inflammatory ligands 27-mag-2016 L. PalazzoloC. ParraviciniCOPPOLINO, GIUSY TINDARAE. GianazzaM.P. AbbracchioI. Eberini + Conference Object -
GPR17, a key receptor involved in oligodendrogenesis: implications for re-myelination strategies 1-set-2016 G.T. CoppolinoD. LeccaD. MarangonC. ParraviciniI. EberiniM.P. Abbracchio + Conference Object -
GPR17-expressing oligodendrocyte precursor cells differentially react to damage in experimental autoimmune encephalomyelitis and cuprizone-induced demyelination 1-ott-2017 Marangon DCoppolino GTLecca DFumagalli MAbbracchio MP. + Conference Object -
Local dysregulation of the GPR17 receptor in neuroinflammatory diseases: implications for remyelination in multiple sclerosis 1-ott-2017 Lecca DCoppolino GTMarangon DAbbracchio MP. + Conference Object -
Mir-125a-3p negatively regulates oligodendrocyte precursor cells maturation and is altered in human multiple sclerosis 1-giu-2017 D. MarangonG.T. CoppolinoM.P. AbbracchioD. Lecca + Article (author) -
MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis 4-ott-2016 D. LeccaD. MarangonG.T. CoppolinoM.P. Abbracchio + Article (author) -
New mechanisms regulating myelination in the central nervous system : the role of GPR17 and of a novel micro-RNA 1-gen-2015 M.P. AbbracchioM. FumagalliD. MarangonG.T. CoppolinoE. BonfantiD. Lecca + Article (author) -
A new miRNA regulating oligodendrocyte maturation in physiology and disease 1-lug-2016 D. MarangonG. T. CoppolinoM. P. AbbracchioD. Lecca + Conference Object -
Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine 1-gen-2017 M. FumagalliD. LeccaG.T. CoppolinoC. ParraviciniM.P. Abbracchio Book Part (author) -
Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis 1-mag-2022 Maria Serena PaladiniDavide MarangonAndrea C. RossettiGiusy T. CoppolinoCamilla NegriVittoria SperoMaria Pia AbbracchioDavide LeccaRaffaella Molteni + Article (author) -