RAFFAELE, STEFANO
RAFFAELE, STEFANO
Dipartimento di Scienze Farmaceutiche
Selective targeting of the oligodendroglial GPR17 receptor improves myelin integrity and motor function in female SOD1G93A mice
2026 S. Raffaele, T. Bonifacino, F.C. Mannella, N. Nguyen, C. Torazza, D. Marangon, E. Chinosi, H.D. Schrøder, E.K. Hejbøl, K. Madsen, L. Marchetti, M.L. Trincavelli, M. Milanese, D. Lecca, K.L. Lambertsen, G. Bonanno, M.P. Abbracchio, M. Fumagalli
The GPR17 agonist galinex restores oligodendrocyte maturation under inflammatory conditions
2026 J.H. Castro E Silva, D. Marangon, M. Boccazzi, S. Raffaele, N. Cignitti, M. Bavetta, I. Arisi, M. Fumagalli, M.P. Abbracchio, D. Lecca
The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors
2025 S.P.H. Alexander, A.P. Davenport, E. Kelly, A.J. Gibb, A.A. Mathie, C.J. Peach, E.L. Veale, J.F. Armstrong, E. Faccenda, S.D. Harding, C. Southan, J.A. Davies, M.P. Abbracchio, G.R. Abraham, A. Agoulnik, W. Alexander, K. Al-Hosaini, M. Bäck, J.G. Baker, N.M. Barnes, R. Bathgate, J. Beaulieu, A.G. Beck-Sickinger, M. Behrens, K.A. Bennett, K.E. Bernstein, B. Bettler, N.J.M. Birdsall, V.A. Blaho, P. Bonaventure, F. Boulay, C. Bousquet, H. Bräuner-Osborne, A.J. Brown, G. Burnstock, M. Busnelli, G. Caló, V. Caruso, J.P. Castaño, K.J. Catt, S. Ceruti, P. Chazot, N. Chiang, B. Chini, A. Christopoulos, J. Chun, A. Cianciulli, O. Civelli, L.H. Clapp, R. Couture, H.M. Cox, Z. Csaba, C. Dahlgren, F.M. Dautzenberg, G. Dent, S.D. Douglas, P. Dournaud, M.L. Dubocovich, S. Eguchi, E. Escher, E.J. Filardo, T. Fong, H.F. Forsman, M. Fumagalli, R.R. Gainetdinov, M.L. Garelja, M. De Gasparo, F. Gbahou, C. Gerard, M. Gershengorn, M. Glass, D.E. Gloriam, F. Gobeil, T.L. Goodfriend, C. Goudet, L. Grätz, K.J. Gregory, C. Gruber, A.L. Gundlach, J. Hamann, J. Hanson, D.S. Hartman, R.L. Hauger, D.L. Hay, A. Heinemann, L. Heitman, D.R. Herr, M.D. Hollenberg, N.D. Holliday, B. Holst, M. Horiuchi, D. Hoyer, L. Hunyady, A. Husain, A.P. Ijzerman, T. Inagami, P.A. Insel, K.A. Jacobson, L.H. Jacobson, R.T. Jensen, R. Jockers, D. Jonnalagadda, S. Karnik, K. Kaupmann, J. Kemp, C. Kennedy, Y. Kihara, J. Kinsolving, T. Kitazawa, P. Kozielewicz, H. Kreienkamp, J.P. Kukkonen, L. Laishram, T. Langenhan, C.J. Langmead, D. Larhammar, K. Leach, D. Lecca, J.D. Lee, S.E. Leeman, J. Leprince, R. Leurs, X.X. Li, I. Liebscher, S.J. Lolait, A. Lupp, R. Macrae, J.J. Maguire, D. Malfacini, M. Manning, D. Marangon, K. Martemyanov, J. Mazella, C.A. Mcardle, S. Melmed, M.C. Michel, L.J. Miller, V. Mitolo, B. Mouillac, C.E. Müller, P.M. Murphy, J. Nahon, R.R. Neubig, T. Ngo, X. Norel, D. Nyimanu, A. O'Carroll, S. Offermanns, M.A. Panaro, M. Parmentier, N. Perry-Hauser, R.G. Pertwee, J. Pin, E.R. Prossnitz, H.C. Qin, M. Quinn, S. Raffaele, R. Ramachandran, M. Ray, R.K. Reinscheid, A.R. Buzón, P. Rondard, M.M. Rosenkilde, G.E. Rovati, C. Ruzza, G.J. Sanger, N. Scholz, T. Schöneberg, G. Schulte, S. Schulz, D.L. Segaloff, C.N. Serhan, A.K. Shukla, K.D. Singh, C.M. Smith, N.J. Smith, C. Stäubert, L.A. Stoddart, Y. Sugimoto, R. Summers, V.P. Tan, D.M. Thal, W.W. Thomas, P.B.M.W.M. Timmermans, K. Tirupula, L. Toll, G. Tulipano, H. Unal, T. Unger, C. Valant, P. Vanderheyden, D. Vaudry, H. Vaudry, J.G. Verbalis, J. Vilardaga, C.S. Walker, J.M. Wang, D.T. Ward, H. Wester, G.B. Willars, T.L. Williams, T.M. Woodruff, H. Wu, C. Yang, C. Yao, R.D. Ye, N. Zaidman
Microglia-Derived Extracellular Vesicles Enhance Oligodendrocyte Maturation by Transcriptionally Regulating Mitochondrial Molecular Pathways
2025 S. Raffaele, M. Lombardi, D. Marangon, M.P. Abbracchio, D. Lecca, C. Verderio, M. Fumagalli
Systemic inhibition of soluble TNF significantly changes glial cell populations leading to improved myelin integrity and better functional outcome after experimental stroke
2025 E. Thougaard, P.V. Nielsen, S. Raffaele, A.N. Nielsen, L.L. Larsen, S. Corradini, J. Havelund, L.V. Becirovic, E.M. Bouwman, M. Fumagalli, N.J. Færgeman, R. Brambilla, B.H. Clausen, A. Wlodarczyk, K.L. Lambertsen
P2Y receptors in GtoPdb v.2025.3
2025 M. Abbracchio, C. Kennedy, B.F. King, D. Lecca, C.E. Müller, D. Marangon, M. Teresa Miras-Portugal, S. Raffaele, V. Ralevic, K.A. Jacobson, K. Inoue, J. Boeynaems, J.L. Boyer, G. Burnstock, S. Ceruti, M. Fumagalli, C. Gachet, R. Hills, R.G. Humphries, G.A. Weisman
Characterisation of GPR17-expressing oligodendrocyte precursors in human ischaemic lesions and correlation with reactive glial responses
2025 S. Raffaele, B.H. Clausen, F.C. Mannella, M. Wirenfeldt, D. Marangon, S.B. Tidgen, S. Corradini, K. Madsen, D. Lecca, M.P. Abbracchio, K.L. Lambertsen, M. Fumagalli
Harnessing anti-TNFR1 therapy has a limited impact on inflammation and motor function after stroke in obese male mice
2025 C. Haarslev, K. Bradshaw, S. Corradini, S. Raffaele, M. Fumagalli, M.S. Buckwalter, K.L. Lambertsen
TNFR2 signaling shapes the sex-specific remyelinating properties of microglia after experimental stroke
2025 S. Raffaele, F.C. Mannella, E. Thougaard, P.V. Nielsen, M. Blickfeldt-Eckhardt, E. Tolosa, J. Münsterberg, T. Magnus, J.D. Mikkelsen, M. Gelderblom, H.H. Nielsen, B.H. Clausen, R. Brambilla, M. Fumagalli, K.L. Lambertsen
Extracellular vesicles released by microglia and macrophages carry endocannabinoids which foster oligodendrocyte differentiation
2024 M. Lombardi, F. Scaroni, M. Gabrielli, S. Raffaele, E. Bonfanti, F. Filipello, P. Giussani, S. Picciolini, N.K. De Rosbo, A. Uccelli, M.T. Golia, G. D’Arrigo, T. Rubino, K. Hooshmand, C. Legido-Quigley, C. Fenoglio, A. Gualerzi, M. Fumagalli, C. Verderio
Neurodegeneration after brain ischemia in aged mice: beneficial effects of Montelukast
2024 M. Muluhie, S. Raffaele, P. Gelosa, L. Castiglioni, B. Mercuriali, J. Rzemieniec, D. Lecca, M.P. Abbracchio, M. Fumagalli, L. Sironi
Microglial TNFR2 signaling regulates the inflammatory response after CNS injury in a sex-specific fashion
2024 S. Raffaele, E. Thougaard, C.C.H. Laursen, H. Gao, K.M. Andersen, P.V. Nielsen, N. Ortí-Casañ, M. Blichfeldt-Eckhardt, S. Koch, M. Deb-Chatterji, T. Magnus, J. Stubbe, K. Madsen, M. Meyer, M. Degn, U.L.M. Eisel, A. Wlodarczyk, M. Fumagalli, B.H. Clausen, R. Brambilla, K.L. Lambertsen
Montelukast improves disease outcome in SOD1G93A female mice by counteracting oligodendrocyte dysfunction and aberrant glial reactivity
2024 S. Raffaele, N. Nguyen, M. Milanese, F.C. Mannella, M. Boccazzi, G. Frumento, G. Bonanno, M.P. Abbracchio, T. Bonifacino, M. Fumagalli
Selective Inhibition of Soluble Tumor Necrosis Factor Alters the Neuroinflammatory Response following Moderate Spinal Cord Injury in Mice
2023 M. Christiansen Lund, D. Gry Ellman, P. Vinther Nielsen, S. Raffaele, M. Fumagalli, R. Guzman, M. Degn, R. Brambilla, M. Meyer, B. Hjelm Clausen, K. Lykke Lambertsen
Altered Purinergic Signaling in Neurodevelopmental Disorders: Focus on P2 Receptors
2023 M. Boccazzi, S. Raffaele, T. Zanettin, M.P. Abbracchio, M. Fumagalli
Dynamics of Microglia Activation in the Ischemic Brain: Implications for Myelin Repair and Functional Recovery
2022 S. Raffaele, M. Fumagalli
The multiple faces of extracellular vesicles released by microglia: Where are we 10 years after?
2022 M. Gabrielli, S. Raffaele, M. Fumagalli, C. Verderio
Not only myelination: the immune-inflammatory functions of oligodendrocytes
2022 M. Boccazzi, S. Raffaele, M. Fumagalli
MICROGLIA-TO-OLIGODENDROCYTE PRECURSOR CELLS COMMUNICATION AFTER STROKE: MOLECULAR MECHANISMS AND IMPLICATIONS FOR MYELIN REPAIR
2021 S. Raffaele
The Distribution of GPR17-Expressing Cells Correlates with White Matter Inflammation Status in Brain Tissues of Multiple Sclerosis Patients
2021 J. Angelini, D. Marangon, S. Raffaele, D. Lecca, M.P. Abbracchio