RAFFAELE, STEFANO
RAFFAELE, STEFANO
Dipartimento di Scienze Farmaceutiche
Selective targeting of the oligodendroglial GPR17 receptor improves myelin integrity and motor function in female SOD1G93A mice
2026 S. Raffaele, T. Bonifacino, F.C. Mannella, N. Nguyen, C. Torazza, D. Marangon, E. Chinosi, H.D. Schrøder, E.K. Hejbøl, K. Madsen, L. Marchetti, M.L. Trincavelli, M. Milanese, D. Lecca, K.L. Lambertsen, G. Bonanno, M.P. Abbracchio, M. Fumagalli
The GPR17 agonist galinex restores oligodendrocyte maturation under inflammatory conditions
2026 J.H. Castro E Silva, D. Marangon, M. Boccazzi, S. Raffaele, N. Cignitti, M. Bavetta, I. Arisi, M. Fumagalli, M.P. Abbracchio, D. Lecca
Microglia-Derived Extracellular Vesicles Enhance Oligodendrocyte Maturation by Transcriptionally Regulating Mitochondrial Molecular Pathways
2025 S. Raffaele, M. Lombardi, D. Marangon, M.P. Abbracchio, D. Lecca, C. Verderio, M. Fumagalli
The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors
2025 S.P.H. Alexander, A.P. Davenport, E. Kelly, A.J. Gibb, A.A. Mathie, C.J. Peach, E.L. Veale, J.F. Armstrong, E. Faccenda, S.D. Harding, C. Southan, J.A. Davies, M.P. Abbracchio, G.R. Abraham, A. Agoulnik, W. Alexander, K. Al-Hosaini, M. Bäck, J.G. Baker, N.M. Barnes, R. Bathgate, J. Beaulieu, A.G. Beck-Sickinger, M. Behrens, K.A. Bennett, K.E. Bernstein, B. Bettler, N.J.M. Birdsall, V.A. Blaho, P. Bonaventure, F. Boulay, C. Bousquet, H. Bräuner-Osborne, A.J. Brown, G. Burnstock, M. Busnelli, G. Caló, V. Caruso, J.P. Castaño, K.J. Catt, S. Ceruti, P. Chazot, N. Chiang, B. Chini, A. Christopoulos, J. Chun, A. Cianciulli, O. Civelli, L.H. Clapp, R. Couture, H.M. Cox, Z. Csaba, C. Dahlgren, F.M. Dautzenberg, G. Dent, S.D. Douglas, P. Dournaud, M.L. Dubocovich, S. Eguchi, E. Escher, E.J. Filardo, T. Fong, H.F. Forsman, M. Fumagalli, R.R. Gainetdinov, M.L. Garelja, M. De Gasparo, F. Gbahou, C. Gerard, M. Gershengorn, M. Glass, D.E. Gloriam, F. Gobeil, T.L. Goodfriend, C. Goudet, L. Grätz, K.J. Gregory, C. Gruber, A.L. Gundlach, J. Hamann, J. Hanson, D.S. Hartman, R.L. Hauger, D.L. Hay, A. Heinemann, L. Heitman, D.R. Herr, M.D. Hollenberg, N.D. Holliday, B. Holst, M. Horiuchi, D. Hoyer, L. Hunyady, A. Husain, A.P. Ijzerman, T. Inagami, P.A. Insel, K.A. Jacobson, L.H. Jacobson, R.T. Jensen, R. Jockers, D. Jonnalagadda, S. Karnik, K. Kaupmann, J. Kemp, C. Kennedy, Y. Kihara, J. Kinsolving, T. Kitazawa, P. Kozielewicz, H. Kreienkamp, J.P. Kukkonen, L. Laishram, T. Langenhan, C.J. Langmead, D. Larhammar, K. Leach, D. Lecca, J.D. Lee, S.E. Leeman, J. Leprince, R. Leurs, X.X. Li, I. Liebscher, S.J. Lolait, A. Lupp, R. Macrae, J.J. Maguire, D. Malfacini, M. Manning, D. Marangon, K. Martemyanov, J. Mazella, C.A. Mcardle, S. Melmed, M.C. Michel, L.J. Miller, V. Mitolo, B. Mouillac, C.E. Müller, P.M. Murphy, J. Nahon, R.R. Neubig, T. Ngo, X. Norel, D. Nyimanu, A. O'Carroll, S. Offermanns, M.A. Panaro, M. Parmentier, N. Perry-Hauser, R.G. Pertwee, J. Pin, E.R. Prossnitz, H.C. Qin, M. Quinn, S. Raffaele, R. Ramachandran, M. Ray, R.K. Reinscheid, A.R. Buzón, P. Rondard, M.M. Rosenkilde, G.E. Rovati, C. Ruzza, G.J. Sanger, N. Scholz, T. Schöneberg, G. Schulte, S. Schulz, D.L. Segaloff, C.N. Serhan, A.K. Shukla, K.D. Singh, C.M. Smith, N.J. Smith, C. Stäubert, L.A. Stoddart, Y. Sugimoto, R. Summers, V.P. Tan, D.M. Thal, W.W. Thomas, P.B.M.W.M. Timmermans, K. Tirupula, L. Toll, G. Tulipano, H. Unal, T. Unger, C. Valant, P. Vanderheyden, D. Vaudry, H. Vaudry, J.G. Verbalis, J. Vilardaga, C.S. Walker, J.M. Wang, D.T. Ward, H. Wester, G.B. Willars, T.L. Williams, T.M. Woodruff, H. Wu, C. Yang, C. Yao, R.D. Ye, N. Zaidman
Harnessing anti-TNFR1 therapy has a limited impact on inflammation and motor function after stroke in obese male mice
2025 C. Haarslev, K. Bradshaw, S. Corradini, S. Raffaele, M. Fumagalli, M.S. Buckwalter, K.L. Lambertsen
TNFR2 signaling shapes the sex-specific remyelinating properties of microglia after experimental stroke
2025 S. Raffaele, F.C. Mannella, E. Thougaard, P.V. Nielsen, M. Blickfeldt-Eckhardt, E. Tolosa, J. Münsterberg, T. Magnus, J.D. Mikkelsen, M. Gelderblom, H.H. Nielsen, B.H. Clausen, R. Brambilla, M. Fumagalli, K.L. Lambertsen
Systemic inhibition of soluble TNF significantly changes glial cell populations leading to improved myelin integrity and better functional outcome after experimental stroke
2025 E. Thougaard, P.V. Nielsen, S. Raffaele, A.N. Nielsen, L.L. Larsen, S. Corradini, J. Havelund, L.V. Becirovic, E.M. Bouwman, M. Fumagalli, N.J. Færgeman, R. Brambilla, B.H. Clausen, A. Wlodarczyk, K.L. Lambertsen
Characterisation of GPR17-expressing oligodendrocyte precursors in human ischaemic lesions and correlation with reactive glial responses
2025 S. Raffaele, B.H. Clausen, F.C. Mannella, M. Wirenfeldt, D. Marangon, S.B. Tidgen, S. Corradini, K. Madsen, D. Lecca, M.P. Abbracchio, K.L. Lambertsen, M. Fumagalli
Montelukast improves disease outcome in SOD1G93A female mice by counteracting oligodendrocyte dysfunction and aberrant glial reactivity
2024 S. Raffaele, N. Nguyen, M. Milanese, F.C. Mannella, M. Boccazzi, G. Frumento, G. Bonanno, M.P. Abbracchio, T. Bonifacino, M. Fumagalli
Extracellular vesicles released by microglia and macrophages carry endocannabinoids which foster oligodendrocyte differentiation
2024 M. Lombardi, F. Scaroni, M. Gabrielli, S. Raffaele, E. Bonfanti, F. Filipello, P. Giussani, S. Picciolini, N.K. De Rosbo, A. Uccelli, M.T. Golia, G. D’Arrigo, T. Rubino, K. Hooshmand, C. Legido-Quigley, C. Fenoglio, A. Gualerzi, M. Fumagalli, C. Verderio
Neurodegeneration after brain ischemia in aged mice: beneficial effects of Montelukast
2024 M. Muluhie, S. Raffaele, P. Gelosa, L. Castiglioni, B. Mercuriali, J. Rzemieniec, D. Lecca, M.P. Abbracchio, M. Fumagalli, L. Sironi
Microglial TNFR2 signaling regulates the inflammatory response after CNS injury in a sex-specific fashion
2024 S. Raffaele, E. Thougaard, C.C.H. Laursen, H. Gao, K.M. Andersen, P.V. Nielsen, N. Ortí-Casañ, M. Blichfeldt-Eckhardt, S. Koch, M. Deb-Chatterji, T. Magnus, J. Stubbe, K. Madsen, M. Meyer, M. Degn, U.L.M. Eisel, A. Wlodarczyk, M. Fumagalli, B.H. Clausen, R. Brambilla, K.L. Lambertsen
Selective Inhibition of Soluble Tumor Necrosis Factor Alters the Neuroinflammatory Response following Moderate Spinal Cord Injury in Mice
2023 M. Christiansen Lund, D. Gry Ellman, P. Vinther Nielsen, S. Raffaele, M. Fumagalli, R. Guzman, M. Degn, R. Brambilla, M. Meyer, B. Hjelm Clausen, K. Lykke Lambertsen
Altered Purinergic Signaling in Neurodevelopmental Disorders: Focus on P2 Receptors
2023 M. Boccazzi, S. Raffaele, T. Zanettin, M.P. Abbracchio, M. Fumagalli
Not only myelination: the immune-inflammatory functions of oligodendrocytes
2022 M. Boccazzi, S. Raffaele, M. Fumagalli
Dynamics of Microglia Activation in the Ischemic Brain: Implications for Myelin Repair and Functional Recovery
2022 S. Raffaele, M. Fumagalli
The multiple faces of extracellular vesicles released by microglia: Where are we 10 years after?
2022 M. Gabrielli, S. Raffaele, M. Fumagalli, C. Verderio
MICROGLIA-TO-OLIGODENDROCYTE PRECURSOR CELLS COMMUNICATION AFTER STROKE: MOLECULAR MECHANISMS AND IMPLICATIONS FOR MYELIN REPAIR
2021 S. Raffaele
Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives
2021 S. Raffaele, M. Boccazzi, M. Fumagalli
Microglial vesicles improve post-stroke recovery by preventing immune cell senescence and favoring oligodendrogenesis
2021 S. Raffaele, P. Gelosa, E. Bonfanti, M. Lombardi, L. Castiglioni, M. Cimino, L. Sironi, M.P. Abbracchio, C. Verderio, M. Fumagalli