SENECI, PIERFAUSTO
SENECI, PIERFAUSTO
Dipartimento di Chimica
Mono- vs. Bis-Guanyl Hydrazone-Decorated Tricyclic Scaffolds: Effects on G-Quadruplex Binding and Selectivity
2026 C. Platella, A. Maiocchi, G. Cipolla, R. Gaglione, A. Arciello, P. Seneci, D. Musumeci, A. Silvani, C. Giannini, D. Montesarchio
MMP2‐Responsive Liposomes Targeting LDLR Enhance the Effectiveness of Anti‐Cancer Drugs in Treating Melanoma
2026 A. Renda, A.I. Antoniou, M. Quadri, S. Comi, A. Amenta, S. Sesana, S. Pellegrino, P. Seneci, M. Koch, V. Denti, G. Paglia, E. Palazzo, R. Lotti, A. Marconi, F. Re
N‐Amidinyl‐Benzodiazaborines as Novel Boron‐Based Scaffolds: Synthesis and Application in Retromer Stabilization
2026 A. Dimasi, A. Montoli, M. Buonaguro, L. Maiorana, G. Macetti, E. Colombo, L. Muzio, G. Donati, D. Passarella, P. Seneci, V. Fasano
Design, synthesis and characterization of novel potential TAU-degraders
2026 G. Tempra, E.M.A. Fassi, G. Grazioso, P. Seneci, D. Passarella
Design, synthesis and in vitro validation of bivalent binders of SARS-CoV-2 spike protein: Obeticholic, betulinic and glycyrrhetinic acids as building blocks
2025 M. Pedrini, L. Pozzi, F. Sacchi, A. Citarella, V. Fasano, P. Seneci, S. Pieraccini, L. Ruberto, H. Perez Peña, A. Garzino-Demo, A. Vitiello, L. Sernicola, A. Borsetti, A. Calistri, C. Parolin, D. Passarella
Aryl Guanyl Hydrazones: A Viable Strategy for Designing BBB-Permeable, Neuroactive Compounds?
2025 E. Colombo, L. Maiorana, G. Donati, A. Menegon, N. Collura, L. Muzio, E. Mastrangelo, M. Milani, L. Marinelli, P. Seneci
Identification of new selective CD36 inhibitors to potentiate HER2-targeted therapy in HER2-positive breast cancer
2025 L. Castagnoli, F. Bonì, M. Bigliardi, P. Toneguzzo, P.A. Corsetto, G. Galasso, A. Franceschini, P. Cocomazzi, V. Regondi, C. Capuzzoni, A.M. Rizzo, F. Ligorio, C. Vernieri, P. Seneci, D. Arosio, E. Tagliabue, E. Mastrangelo, M. Milani, S.M. Pupa
Automated fluorine-18 radiolabeling via an alkyne–azide cycloaddition reaction on a dual peptide-functionalized liposome surface for in vivo PET imaging
2025 M. Iannone, M. Kravicz, P. Rainone, A.I. Antoniou, S. Stucchi, S. Valtorta, A. Amenta, E.A. Turolla, S. Pellegrino, D. Passarella, E. Vino, S. Todde, F. Re, P. Seneci, R.M. Moresco
Design, synthesis and characterization of aryl bis-guanyl hydrazones as RNA binders of C9orf72 G4C2 extended repeats
2025 A. Maiocchi, M. Pedrini, V. Ferrari, A.S. Assunçao Carreira, V.M. D'Amore, F. Santoro, A. Di Porzio, M. Bosetti, R. Cristofani, A. Silvani, D. Brancaccio, L. Marinelli, F.S. Di Leva, A. Provenzani, A. Poletti, P. Seneci
Synthesis and Preliminary Evaluation of Tanshinone Mimic Conjugates for Mechanism of Action Studies
2025 G. Assoni, Á.S. Assunção Carreira, M. Tomiello, P. Seneci, A. Provenzani, D. Arosio
Engineered Glibenclamide-Loaded Nanovectors Hamper Inflammasome Activation in an Ex Vivo Alzheimer’s Disease Model—A Novel Potential Therapy for Neuroinflammation: A Pilot Study
2025 F. La Rosa, S. Agostini, E. Bolognesi, I. Marventano, R. Mancuso, F.R. Guerini, A. Hernis, L.A. Citterio, F. Piancone, P.D. Trimarchi, J. Navarro, F. Rossetto, A. Amenta, P. Seneci, S. Sesana, F. Re, M. Clerici, M. Saresella
An Inducible Neural Stem Progenitor Cell Model for Testing Therapeutic Interventions Against Neurodegeneration FENIB
2025 A. Giustini, A. Maiocchi, I. Serangeli, M. Pedrini, A. Quintiliani, V. Sabato, F. Bonato, P. Seneci, G. Lupo, D. Passarella, E. Miranda
Stabilization of the retromer complex: analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface
2024 E. Fagnani, F. Boni, P. Seneci, D. Gornati, L. Muzio, E. Mastrangelo, M. Milani
A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy
2024 A. Amenta, S. Comi, M. Kravicz, S. Sesana, A. Antoniou, D. Passarella, P. Seneci, S. Pellegrino, F. Re
Novel, soluble 3-heteroaryl-substituted tanshinone mimics attenuate the inflammatory response in murine macrophages
2024 E. Facen, G. Assoni, G. Donati, D. Paladino, A. Carreira, I. Bonomo, V.L. Pietra, R. Lotti, J. Houser, L.L. Fava, P. Seneci, L. Marinelli, D. Arosio, A. Provenzani
A combined approach of structure‐based virtual screening and NMR to interrupt the PD‐1/PD‐L1 axis: Biphenyl‐benzimidazole containing compounds as novel PD‐L1 inhibitors
2024 G. Donati, M. Viviano, V.M. D'Amore, A. Cipriano, I. Diakogiannaki, J. Amato, S. Tomassi, D. Brancaccio, P. Russomanno, F.S. Di Leva, D. Arosio, P. Seneci, S. Taliani, K. Magiera‐mularz, B. Musielak, L. Skalniak, T.A. Holak, S. Castellano, V. La Pietra, L. Marinelli
Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth
2024 A. Balboni, C. D'Angelo, N. Collura, S. Brusco, C. Di Berardino, A. Targa, B. Massoti, E. Mastrangelo, M. Milani, P. Seneci, V. Broccoli, L. Muzio, R. Galli, A. Menegon
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design
2023 G. Donati, V.M. D'Amore, P. Russomanno, L. Cerofolini, J. Amato, S. Marzano, M. Salobehaj, D. Rizzo, G. Assoni, A. Carotenuto, V. La Pietra, D. Arosio, P. Seneci, M. Fragai, D. Brancaccio, F.S. Di Leva, L. Marinelli
SPRi analysis of molecular interactions of mApoE-functionalized liposomes as drug delivery systems for brain diseases
2023 S. Picciolini, F. Roda, A. Gualerzi, V. Mangolini, L. Forleo, A. Mangolini, S. Sesana, A. Antoniou, F. Re, P. Seneci, M. Bedoni
Raman Spectroscopy Characterization of Multi-Functionalized Liposomes as Drug-Delivery Systems for Neurological Disorders
2023 F. Rodà, S. Picciolini, V. Mangolini, A. Gualerzi, P. Seneci, A. Renda, S. Sesana, F. Re, M. Bedoni