SENECI, PIERFAUSTO
SENECI, PIERFAUSTO
Dipartimento di Chimica
Synthesis and Preliminary Evaluation of Tanshinone Mimic Conjugates for Mechanism of Action Studies
2025 G. Assoni, Á.S. Assunção Carreira, M. Tomiello, P. Seneci, A. Provenzani, D. Arosio
An Inducible Neural Stem Progenitor Cell Model for Testing Therapeutic Interventions Against Neurodegeneration FENIB
2025 A. Giustini, A. Maiocchi, I. Serangeli, M. Pedrini, A. Quintiliani, V. Sabato, F. Bonato, P. Seneci, G. Lupo, D. Passarella, E. Miranda
Design, synthesis and in vitro validation of bivalent binders of SARS-CoV-2 spike protein: Obeticholic, betulinic and glycyrrhetinic acids as building blocks
2025 M. Pedrini, L. Pozzi, F. Sacchi, A. Citarella, V. Fasano, P. Seneci, S. Pieraccini, L. Ruberto, H. Perez Peña, A. Garzino-Demo, A. Vitiello, L. Sernicola, A. Borsetti, A. Calistri, C. Parolin, D. Passarella
Identification of new selective CD36 inhibitors to potentiate HER2-targeted therapy in HER2-positive breast cancer
2025 L. Castagnoli, F. Bonì, M. Bigliardi, P. Toneguzzo, P.A. Corsetto, G. Galasso, A. Franceschini, P. Cocomazzi, V. Regondi, C. Capuzzoni, A.M. Rizzo, F. Ligorio, C. Vernieri, P. Seneci, D. Arosio, E. Tagliabue, E. Mastrangelo, M. Milani, S.M. Pupa
Aryl Guanyl Hydrazones: A Viable Strategy for Designing BBB-Permeable, Neuroactive Compounds?
2025 E. Colombo, L. Maiorana, G. Donati, A. Menegon, N. Collura, L. Muzio, E. Mastrangelo, M. Milani, L. Marinelli, P. Seneci
Design, synthesis and characterization of aryl bis-guanyl hydrazones as RNA binders of C9orf72 G4C2 extended repeats
2025 A. Maiocchi, M. Pedrini, V. Ferrari, A.S. Assunçao Carreira, V.M. D'Amore, F. Santoro, A. Di Porzio, M. Bosetti, R. Cristofani, A. Silvani, D. Brancaccio, L. Marinelli, F.S. Di Leva, A. Provenzani, A. Poletti, P. Seneci
Automated fluorine-18 radiolabeling via an alkyne–azide cycloaddition reaction on a dual peptide-functionalized liposome surface for in vivo PET imaging
2025 M. Iannone, M. Kravicz, P. Rainone, A.I. Antoniou, S. Stucchi, S. Valtorta, A. Amenta, E.A. Turolla, S. Pellegrino, D. Passarella, E. Vino, S. Todde, F. Re, P. Seneci, R.M. Moresco
Novel, soluble 3-heteroaryl-substituted tanshinone mimics attenuate the inflammatory response in murine macrophages
2024 E. Facen, G. Assoni, G. Donati, D. Paladino, A. Carreira, I. Bonomo, V.L. Pietra, R. Lotti, J. Houser, L.L. Fava, P. Seneci, L. Marinelli, D. Arosio, A. Provenzani
Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth
2024 A. Balboni, C. D'Angelo, N. Collura, S. Brusco, C. Di Berardino, A. Targa, B. Massoti, E. Mastrangelo, M. Milani, P. Seneci, V. Broccoli, L. Muzio, R. Galli, A. Menegon
A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy
2024 A. Amenta, S. Comi, M. Kravicz, S. Sesana, A. Antoniou, D. Passarella, P. Seneci, S. Pellegrino, F. Re
Stabilization of the retromer complex: analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface
2024 E. Fagnani, F. Boni, P. Seneci, D. Gornati, L. Muzio, E. Mastrangelo, M. Milani
A combined approach of structure‐based virtual screening and NMR to interrupt the PD‐1/PD‐L1 axis: Biphenyl‐benzimidazole containing compounds as novel PD‐L1 inhibitors
2024 G. Donati, M. Viviano, V.M. D'Amore, A. Cipriano, I. Diakogiannaki, J. Amato, S. Tomassi, D. Brancaccio, P. Russomanno, F.S. Di Leva, D. Arosio, P. Seneci, S. Taliani, K. Magiera‐mularz, B. Musielak, L. Skalniak, T.A. Holak, S. Castellano, V. La Pietra, L. Marinelli
Synthesis and Characterization of Edaravone Analogues as Remyelinating Agents and Putative Mechanistic Probes
2023 E. Colombo, S. Olla, C. Minnelli, A. Formato, C. Veroni, S. Corbisiero, M. Pericolo, C. Siguri, G. Mobbili, C. Agresti, P. Seneci
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design
2023 G. Donati, V.M. D'Amore, P. Russomanno, L. Cerofolini, J. Amato, S. Marzano, M. Salobehaj, D. Rizzo, G. Assoni, A. Carotenuto, V. La Pietra, D. Arosio, P. Seneci, M. Fragai, D. Brancaccio, F.S. Di Leva, L. Marinelli
HuR modulation with tanshinone mimics impairs LPS response in murine macrophages
2023 I. Bonomo, G. Assoni, V.L. Pietra, G. Canarutto, E. Facen, G. Donati, C. Zucal, S. Genovese, M. Micaelli, A. Pérez-Ràfols, S. Robbiati, D.L. Kontoyannis, M. De Matteo, M. Fragai, P. Seneci, L. Marinelli, D. Arosio, S. Piazza, A. Provenzani
SPRi analysis of molecular interactions of mApoE-functionalized liposomes as drug delivery systems for brain diseases
2023 S. Picciolini, F. Roda, A. Gualerzi, V. Mangolini, L. Forleo, A. Mangolini, S. Sesana, A. Antoniou, F. Re, P. Seneci, M. Bedoni
Raman Spectroscopy Characterization of Multi-Functionalized Liposomes as Drug-Delivery Systems for Neurological Disorders
2023 F. Rodà, S. Picciolini, V. Mangolini, A. Gualerzi, P. Seneci, A. Renda, S. Sesana, F. Re, M. Bedoni
2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles
2023 A.I. Antoniou, G. Nordio, M. Luisa Di Paolo, E. Colombo, B. Gaffuri, L. Polito, A. Amenta, P. Seneci, L. Dalla Via, D. Perdicchia, D. Passarella
Synthesis and Preliminary Characterization of Putative Anle138b-Centered PROTACs against α-Synuclein Aggregation
2023 M. Pedrini, A. Iannielli, L. Meneghelli, D. Passarella, V. Broccoli, P. Seneci
Glibenclamide-Loaded Engineered Nanovectors (GNVs) modulate autophagy and NLRP3-inflammasome activation
2023 M. Saresella, C.P. Zoia, F. La Rosa, C. Bazzini, G. Sala, E. Grassenis, I. Marventano, A. Hernis, F. Piancone, E. Conti, S. Sesana, F. Re, P. Seneci, C. Ferrarese, M. Clerici