SILVANI, ALESSANDRA
SILVANI, ALESSANDRA
Dipartimento di Chimica
PROTAC-mediated degradation of peroxisomal d-aspartate oxidase: A novel strategy to modulate d-aspartate homeostasis for schizophrenia treatment
2026 M. Galli, V. Rabattoni, M. Cavinato, F. Vasile, I. Gado, K. Ulfat, H. Shehi, A. Silvani, D. Passarella, A. Citarella, L. Pollegioni, M. Nardini
Mono- vs. Bis-Guanyl Hydrazone-Decorated Tricyclic Scaffolds: Effects on G-Quadruplex Binding and Selectivity
2026 C. Platella, A. Maiocchi, G. Cipolla, R. Gaglione, A. Arciello, P. Seneci, D. Musumeci, A. Silvani, C. Giannini, D. Montesarchio
Design, synthesis and biological evaluation of PROTACs targeting hDASPO
2025 M. Galli, A. Citarella, M. Cavinato, I. Gado, V. Rabattoni, H. Shehi, M. Nardini, A. Silvani, V. Fasano, F. Vasile, L. Pollegioni, D. Passarella
Functionalization of E3 ligase recruiters in the green solvent Cyrene: a sustainable approach for the synthesis of PROTACs precursors
2025 M. Galli, A. Citarella, A. Silvani
PROTAC technology for the degradation of hDASPO: from design to synthesis to biophysical and cellular evaluation
2025 M. Galli, A. Citarella, M. Cavinato, I. Gado, V. Rabattoni, H. Shehi, M. Nardini, A. Silvani, V. Fasano, F. Vasile, L. Pollegioni, D. Passarella
Design, synthesis and characterization of aryl bis-guanyl hydrazones as RNA binders of C9orf72 G4C2 extended repeats
2025 A. Maiocchi, M. Pedrini, V. Ferrari, A.S. Assunçao Carreira, V.M. D'Amore, F. Santoro, A. Di Porzio, M. Bosetti, R. Cristofani, A. Silvani, D. Brancaccio, L. Marinelli, F.S. Di Leva, A. Provenzani, A. Poletti, P. Seneci
Functionalization of E3-ligase recruiters in the green solvent Cyrene: a sustainable approach for the synthesis of PROTAC precursors
2025 M. Galli, A. Citarella, A. Silvani
Design and synthesis of CD70 inhibitors: a potential way for the treatment of ulcerative colitis
2025 M. Galli, A. Silvani, G. Grazioso, E.G. Milano, E.M.A. Fassi, M. Bramuzzo, A. Muzzo, G. Stocco, M. Lucafò
Sustainable Synthesis of 1,2,3‐Triazoles using Cyrene as a Biodegradable Solvent in Click Chemistry
2025 A. Citarella, A. Fiori, A. Silvani, D. Passarella, V. Fasano
Synthesis and Multitarget Inhibitory Effect of Indole-Based Ethyl Cinnamate Derivatives against SARS-CoV-2 Mpro and Cathepsins for Broad-Spectrum Anti-Coronavirus Activity
2025 A. Citarella, G. Sibile, D. Moi, A. Dimasi, T. Braga, L. Dal Col, L. Ruberto, S. Pieraccini, M. Sironi, N. Micale, T. Schirmeister, V. Fasano, A. Silvani, C. Giannini, G. Gribaudo, D. Passarella
Structure-Based Discovery of Hsp90/HDAC6 Dual Inhibitors Targeting Aggressive Prostate Cancer
2025 A. Citarella, S. Belluti, D. Bonanni, D. Moi, I. Piccinini, A. Rinaldi, C. Papulino, R. Benedetti, L. Cuoghi, S.D. Ciolo, A. Silvani, L. Altucci, L. Pinzi, S. Franchini, D. Passarella, C. Sorbi, C. Giannini, C. Imbriano, G. Rastelli
Synthesis and multitarget inhibitory effect of indole-based ethyl cinnamate derivatives against SARS-CoV-2 Mpro and cathepsins for broad-spectrum anti-coronavirus activity
2025 A. Citarella, G. Sibille, D. Moi, A. Dimasi, T. Braga, L.D. Col, L. Ruberto, S. Pieraccini, M. Sironi, N. Micale, T. Schirmeister, V. Fasano, A. Silvani, C. Giannini, G. Gribaudo, D. Passarella
Synthesis of α-fluorocinnamate derivatives as novel cathepsin S inhibitors with in vitro antiproliferative activity against pancreatic cancer cells
2024 A. Citarella, S. Petrella, D. Moi, A. Dimasi, T. Braga, L. Ruberto, S. Pieraccini, M. Sironi, N. Micale, T. Schirmeister, G. Damia, V. Fasano, A. Silvani, C. Giannini, D. Passarella
PCSK9 inhibitors: a patent review 2018-2023
2024 E.M.A. Fassi, A. Citarella, M. Albani, E.G. Milano, L. Legnani, C. Lammi, A. Silvani, G. Grazioso
Chemical modifications of aromatic scaffolds for the development of new G4 ligands
2024 S. Di Ciolo, B. Airoldi, L.C.M. Pariani, C.F. Morelli, C. Giannini, A. Silvani, D. Malpicci, E. Cariati, E. Lucenti, C. Platella, D. Musumeci, R. Gaglione, A. Arciello, D. Montesarchio
Innovative molecular platforms for G-quadruplex stabilizatioN
2024 S. Di Ciolo, B. Airoldi, L.C.M. Pariani, C.F. Morelli, C. Giannini, A. Silvani, D. Malpicci, E. Cariati, E. Lucenti, C. Platella, D. Musumeci, R. Gaglione, A. Arciello, D. Montesarchio
Innovative molecular platforms for G-quadruplex stabilization
2024 S. Di Ciolo, B. Airoldi, L.C.M. Pariani, C.F. Morelli, C. Giannini, A. Silvani, D. Malpicci, E. Cariati, E. Lucenti, C. Platella, D. Musumeci, R. Gaglione, A. Arciello, D. Montesarchio
Alkene carboamination/oxidative denitrogenation of 3-allyl-3-hydrazinylindolin-2-ones: one-pot entry to spirocyclopropyloxindoles
2024 M. Manenti, T. Villa, G. Macetti, A. Silvani
Nirmatrelvir: from discovery to modern and alternative synthetic approaches
2024 M. Galli, F. Migliano, V. Fasano, A. Silvani, D. Passarella, A. Citarella
Application of the PROTAC technology for the modulation of hDASPO activity
2024 M. Galli, A. Citarella, M. Cavinato, I. Gado, V. Rabattoni, H. Shehi, M. Nardini, A. Silvani, V. Fasano, F. Vasile, L. Pollegioni, D. Passarella