OTTOBONI, LINDA
OTTOBONI, LINDA
Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti
Shaping the Neurovascular Unit Exploiting Human Brain Organoids
2024 M. Rizzuti, V. Melzi, L. Brambilla, L. Quetti, L. Sali, L. Ottoboni, M. Meneri, A. Ratti, F. Verde, N. Ticozzi, G.P. Comi, S. Corti, E. Abati
Unleashing the potential of mRNA therapeutics for inherited neurological diseases
2024 E. Monfrini, G. Baso, D. Ronchi, M. Meneri, D. Gagliardi, L. Quetti, F. Verde, N. Ticozzi, A. Ratti, A. Di Fonzo, G.P. Comi, L. Ottoboni, S. Corti
Identification of Novel Biomarkers of Spinal Muscular Atrophy and Therapeutic Response by Proteomic and Metabolomic Profiling of Human Biological Fluid Samples
2023 M. Meneri, E. Abati, D. Gagliardi, I. Faravelli, V. Parente, A. Ratti, F. Verde, N. Ticozzi, G.P. Comi, L. Ottoboni, S. Corti
Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects That Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells
2023 I. Pagani, L. Ottoboni, P. Panina-Bordignon, G. Martino, G. Poli, S. Taylor, J.E. Turnbull, E. Yates, E. Vicenzi
Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study
2023 A. Genchi, E. Brambilla, F. Sangalli, M. Radaelli, M. Bacigaluppi, R. Furlan, A. Andolfo, D. Drago, C. Magagnotti, G.M. Scotti, R. Greco, P. Vezzulli, L. Ottoboni, M. Bonopane, D. Capilupo, F. Ruffini, D. Belotti, B. Cabiati, S. Cesana, G. Matera, L. Leocani, V. Martinelli, L. Moiola, L. Vago, P. Panina-Bordignon, A. Falini, F. Ciceri, A. Uglietti, M.P. Sormani, G. Comi, M.A. Battaglia, M.A. Rocca, L. Storelli, E. Pagani, G. Gaipa, G. Martino
Multi-omics profiling of CSF from spinal muscular atrophy type 3 patients after nusinersen treatment: a 2-year follow-up multicenter retrospective study
2023 I. Faravelli, D. Gagliardi, E. Abati, M. Meneri, J. Ongaro, F. Magri, V. Parente, L. Petrozzi, G. Ricci, F. Farè, G. Garrone, M. Fontana, D. Caruso, G. Siciliano, G.P. Comi, A. Govoni, S. Corti, L. Ottoboni
Combined RNA interference and gene replacement therapy targeting MFN2 as proof of principle for the treatment of Charcot-Marie-Tooth type 2A
2023 F. Rizzo, S. Bono, M.D. Ruepp, S. Salani, L. Ottoboni, E. Abati, V. Melzi, C. Cordiglieri, S. Pagliarani, R. De Gioia, A. Anastasia, M. Taiana, M. Garbellini, S. Lodato, P. Kunderfranco, D. Cazzato, D. Cartelli, C. Lonati, N. Bresolin, G. Comi, M. Nizzardo, S. Corti
iAstrocytes do not restrain T cell proliferation in vitro
2023 E. Colombo, A. De Angelis, C. Bassani, F. Ruffini, L. Ottoboni, L. Garzetti, A. Finardi, G. Martino, R. Furlan, C. Farina
Genomic and transcriptomic advances in amyotrophic lateral sclerosis
2023 M. Rizzuti, L. Sali, V. Melzi, S. Scarcella, G. Costamagna, L. Ottoboni, L. Quetti, L. Brambilla, D. Papadimitriou, F. Verde, A. Ratti, N. Ticozzi, G.P. Comi, S. Corti, D. Gagliardi
A Whole-Genome Sequencing Study Implicates GRAMD1B in Multiple Sclerosis Susceptibility
2022 F. Esposito, A.M. Osiceanu, M. Sorosina, L. Ottoboni, B. Bollman, S. Santoro, B. Bettegazzi, A. Zauli, F. Clarelli, E. Mascia, A. Calabria, D. Zacchetti, R. Capra, M. Ferrari, P. Provero, D. Lazarevic, D. Cittaro, P. Carrera, N. Patsopoulos, D. Toniolo, A.D. Sadovnick, G. Martino, P.L. De Jager, G. Comi, E. Stupka, C. Vilariño-Güell, L. Piccio, F. Martinelli Boneschi
Heparin Protects Human Neural Progenitor Cells from Zika Virus-Induced Cell Death While Preserving Their Differentiation into Mature Neuroglial Cells
2022 I. Pagani, L. Ottoboni, P. Podini, S. Ghezzi, E. Brambilla, S. Bezukladova, D. Corti, M.E. Bianchi, M.R. Capobianchi, G. Poli, P. Panina-Bordignon, E.A. Yates, G. Martino, E. Vicenzi
cAMP Response Element-Binding Protein Controls the Appearance of Neuron-Like Traits in Chorion Mesenchymal Cells
2022 G. Innamorati, G. Ridolfi, F. Steccanella, A. Bormetti, A. Dallatana, C. Bozzetto, L. Ottoboni, M. Di Chio, L. Giacomello
Transcriptional effects of fingolimod treatment on peripheral T cells in relapsing remitting multiple sclerosis patients
2022 G. Sferruzza, F. Clarelli, E. Mascia, L. Ferrè, L. Ottoboni, M. Sorosina, S. Santoro, M. Filippi, P. Provero, F. Esposito
Targeting PTB for Glia‐to‐Neuron Reprogramming In Vitro and In Vivo for Therapeutic Development in Neurological Diseases
2022 M. Contardo, R. De Gioia, D. Gagliardi, G.P. Comi, L. Ottoboni, M. Nizzardo, S. Corti
One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2
2021 K. Chanoumidou, B. Hernández-Rodríguez, F. Windener, C. Thomas, M. Stehling, S. Mozafari, S. Albrecht, L. Ottoboni, J. Antel, K. Kim, S. Velychko, Q.L. Cui, Y.K.T. Xu, G. Martino, J. Winkler, H.R. Schöler, A. Baron-Van Evercooren, O. Boespflug-Tanguy, J.M. Vaquerizas, M. Ehrlich, T. Kuhlmann
Transcriptomic Analysis of Peripheral Monocytes upon Fingolimod Treatment in Relapsing Remitting Multiple Sclerosis Patients
2021 G. Sferruzza, F. Clarelli, E. Mascia, L. Ferrè, L. Ottoboni, M. Sorosina, S. Santoro, L. Moiola, V. Martinelli, G. Comi, F. Martinelli Boneschi, M. Filippi, P. Provero, F. Esposito
Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo
2020 S. Mozafari, L. Starost, B. Manot-Saillet, B. Garcia-Diaz, Y.K.T. Xu, D. Roussel, M.J.F. Levy, L. Ottoboni, K. Kim, H.R. Schöler, T.E. Kennedy, J.P. Antel, G. Martino, M.C. Angulo, T. Kuhlmann, A. Baron-Van Evercooren
Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration
2020 E. Colombo, C. Bassani, A. De Angelis, F. Ruffini, L. Ottoboni, G. Comi, G. Martino, C. Farina
Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis
2020 L. Starost, M. Lindner, M. Herold, Y.K.T. Xu, H.C.A. Drexler, K. Heß, M. Ehrlich, L. Ottoboni, F. Ruffini, M. Stehling, A. Röpke, C. Thomas, H.R. Schöler, J. Antel, J. Winkler, G. Martino, L. Klotz, T. Kuhlmann
Therapeutic Plasticity of Neural Stem Cells
2020 L. Ottoboni, B. von Wunster, G. Martino