OTTOBONI, LINDA
OTTOBONI, LINDA
Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors
2024 K.F. Suazo, V. Mishra, S. Maity, S.A. Auger, K. Justyna, A.M. Petre, L. Ottoboni, J. Ongaro, S.P. Corti, F. Lotti, S. Przedborski, M.D. Distefano
Unleashing the potential of mRNA therapeutics for inherited neurological diseases
2024 E. Monfrini, G. Baso, D. Ronchi, M. Meneri, D. Gagliardi, L. Quetti, F. Verde, N. Ticozzi, A. Ratti, A. Di Fonzo, G.P. Comi, L. Ottoboni, S. Corti
Shaping the Neurovascular Unit Exploiting Human Brain Organoids
2024 M. Rizzuti, V. Melzi, L. Brambilla, L. Quetti, L. Sali, L. Ottoboni, M. Meneri, A. Ratti, F. Verde, N. Ticozzi, G.P. Comi, S. Corti, E. Abati
iAstrocytes do not restrain T cell proliferation in vitro
2023 E. Colombo, A. De Angelis, C. Bassani, F. Ruffini, L. Ottoboni, L. Garzetti, A. Finardi, G. Martino, R. Furlan, C. Farina
Heparin Precursors with Reduced Anticoagulant Properties Retain Antiviral and Protective Effects That Potentiate the Efficacy of Sofosbuvir against Zika Virus Infection in Human Neural Progenitor Cells
2023 I. Pagani, L. Ottoboni, P. Panina-Bordignon, G. Martino, G. Poli, S. Taylor, J.E. Turnbull, E. Yates, E. Vicenzi
Identification of Novel Biomarkers of Spinal Muscular Atrophy and Therapeutic Response by Proteomic and Metabolomic Profiling of Human Biological Fluid Samples
2023 M. Meneri, E. Abati, D. Gagliardi, I. Faravelli, V. Parente, A. Ratti, F. Verde, N. Ticozzi, G.P. Comi, L. Ottoboni, S. Corti
Combined RNA interference and gene replacement therapy targeting MFN2 as proof of principle for the treatment of Charcot-Marie-Tooth type 2A
2023 F. Rizzo, S. Bono, M.D. Ruepp, S. Salani, L. Ottoboni, E. Abati, V. Melzi, C. Cordiglieri, S. Pagliarani, R. De Gioia, A. Anastasia, M. Taiana, M. Garbellini, S. Lodato, P. Kunderfranco, D. Cazzato, D. Cartelli, C. Lonati, N. Bresolin, G. Comi, M. Nizzardo, S. Corti
Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study
2023 A. Genchi, E. Brambilla, F. Sangalli, M. Radaelli, M. Bacigaluppi, R. Furlan, A. Andolfo, D. Drago, C. Magagnotti, G.M. Scotti, R. Greco, P. Vezzulli, L. Ottoboni, M. Bonopane, D. Capilupo, F. Ruffini, D. Belotti, B. Cabiati, S. Cesana, G. Matera, L. Leocani, V. Martinelli, L. Moiola, L. Vago, P. Panina-Bordignon, A. Falini, F. Ciceri, A. Uglietti, M.P. Sormani, G. Comi, M.A. Battaglia, M.A. Rocca, L. Storelli, E. Pagani, G. Gaipa, G. Martino
Genomic and transcriptomic advances in amyotrophic lateral sclerosis
2023 M. Rizzuti, L. Sali, V. Melzi, S. Scarcella, G. Costamagna, L. Ottoboni, L. Quetti, L. Brambilla, D. Papadimitriou, F. Verde, A. Ratti, N. Ticozzi, G.P. Comi, S. Corti, D. Gagliardi
Multi-omics profiling of CSF from spinal muscular atrophy type 3 patients after nusinersen treatment: a 2-year follow-up multicenter retrospective study
2023 I. Faravelli, D. Gagliardi, E. Abati, M. Meneri, J. Ongaro, F. Magri, V. Parente, L. Petrozzi, G. Ricci, F. Farè, G. Garrone, M. Fontana, D. Caruso, G. Siciliano, G.P. Comi, A. Govoni, S. Corti, L. Ottoboni
A Whole-Genome Sequencing Study Implicates GRAMD1B in Multiple Sclerosis Susceptibility
2022 F. Esposito, A.M. Osiceanu, M. Sorosina, L. Ottoboni, B. Bollman, S. Santoro, B. Bettegazzi, A. Zauli, F. Clarelli, E. Mascia, A. Calabria, D. Zacchetti, R. Capra, M. Ferrari, P. Provero, D. Lazarevic, D. Cittaro, P. Carrera, N. Patsopoulos, D. Toniolo, A.D. Sadovnick, G. Martino, P.L. De Jager, G. Comi, E. Stupka, C. Vilariño-Güell, L. Piccio, F. Martinelli Boneschi
cAMP Response Element-Binding Protein Controls the Appearance of Neuron-Like Traits in Chorion Mesenchymal Cells
2022 G. Innamorati, G. Ridolfi, F. Steccanella, A. Bormetti, A. Dallatana, C. Bozzetto, L. Ottoboni, M. Di Chio, L. Giacomello
Heparin Protects Human Neural Progenitor Cells from Zika Virus-Induced Cell Death While Preserving Their Differentiation into Mature Neuroglial Cells
2022 I. Pagani, L. Ottoboni, P. Podini, S. Ghezzi, E. Brambilla, S. Bezukladova, D. Corti, M.E. Bianchi, M.R. Capobianchi, G. Poli, P. Panina-Bordignon, E.A. Yates, G. Martino, E. Vicenzi
Transcriptional effects of fingolimod treatment on peripheral T cells in relapsing remitting multiple sclerosis patients
2022 G. Sferruzza, F. Clarelli, E. Mascia, L. Ferrè, L. Ottoboni, M. Sorosina, S. Santoro, M. Filippi, P. Provero, F. Esposito
Targeting PTB for Glia‐to‐Neuron Reprogramming In Vitro and In Vivo for Therapeutic Development in Neurological Diseases
2022 M. Contardo, R. De Gioia, D. Gagliardi, G.P. Comi, L. Ottoboni, M. Nizzardo, S. Corti
Transcriptomic Analysis of Peripheral Monocytes upon Fingolimod Treatment in Relapsing Remitting Multiple Sclerosis Patients
2021 G. Sferruzza, F. Clarelli, E. Mascia, L. Ferrè, L. Ottoboni, M. Sorosina, S. Santoro, L. Moiola, V. Martinelli, G. Comi, F. Martinelli Boneschi, M. Filippi, P. Provero, F. Esposito
One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2
2021 K. Chanoumidou, B. Hernández-Rodríguez, F. Windener, C. Thomas, M. Stehling, S. Mozafari, S. Albrecht, L. Ottoboni, J. Antel, K. Kim, S. Velychko, Q.L. Cui, Y.K.T. Xu, G. Martino, J. Winkler, H.R. Schöler, A. Baron-Van Evercooren, O. Boespflug-Tanguy, J.M. Vaquerizas, M. Ehrlich, T. Kuhlmann
Siponimod (BAF312) Activates Nrf2 While Hampering NFκB in Human Astrocytes, and Protects From Astrocyte-Induced Neurodegeneration
2020 E. Colombo, C. Bassani, A. De Angelis, F. Ruffini, L. Ottoboni, G. Comi, G. Martino, C. Farina
Endogenous neural precursor cells in health and disease
2020 M. Bacigaluppi, G. Sferruzza, E. Butti, L. Ottoboni, G. Martino
Convergence between Microglia and Peripheral Macrophages Phenotype during Development and Neuroinflammation
2020 F. Grassivaro, R. Menon, M. Acquaviva, L. Ottoboni, F. Ruffini, A. Bergamaschi, L. Muzio, C. Farina, G. Martino