CONFORTI, PAOLA
CONFORTI, PAOLA
Dipartimento di Bioscienze
A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2
2020 D. Besusso, A. Cossu, A. Mohamed, M. Cernigoj, P. Codega, M. Galimberti, I. Campus, P. Conforti, E. Cattaneo
ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease
2021 F. Cozzolino, E. Vezzoli, C. Cheroni, D. Besusso, P. Conforti, M. Valenza, I. Iacobucci, V. Monaco, G. Birolini, M. Bombaci, A. Falqui, P. Saftig, R.L. Rossi, M. Monti, E. Cattaneo, C. Zuccato
Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models
2013 P. Conforti, C. Zuccato, G. Gaudenzi, A. Ieraci, S. Camnasio, N.J. Buckley, C. Mutti, F. Cotelli, A. Contini, E. Cattaneo
Biphasic bioconversion of naphthalenes into dihydrodiols : solvent effects and substrate differences
2003 S. Bernasconi, F. Orsini, G.G. Sello, P. Conforti, M. Tansi, E. Galli, P. Di Gennaro, G. Bestetti
Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease : restoration by the neuroprotective compound CEP-134
2008 P. Conforti, C. Ramos, B.L. Apostol, D.A. Simmons, H.P. Nguyen, O. Riess, L.M. Thompson, C. Zuccato, E. Cattaneo
Brain Regional Identity and Cell Type Specificity Landscape of Human Cortical Organoid Models
2022 M. Magni, B. Bossi, P. Conforti, M. Galimberti, F. Dezi, T. Lischetti, X. He, R.A. Barker, C. Zuccato, I. Espuny-Camacho, E. Cattaneo
CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice
2008 B.L. Apostol, D.A. Simmons, C. Zuccato, K. Illes, J. Pallos, M. Casale, P. Conforti, C. Ramos, M. Roarke, S. Kathuria, E. Cattaneo, J.L. Marsh, L.M. Thompson
DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis
2020 A. Thiruvalluvan, E.P. de Mattos, J.F. Brunsting, R. Bakels, D. Serlidaki, L. Barazzuol, P. Conforti, A. Fatima, S. Koyuncu, E. Cattaneo, D. Vilchez, S. Bergink, E.H.W.G. Boddeke, S. Copray, H.H. Kampinga
Dose-dependent and disease-modifying effects of striatal infusion of cholesterol in Huntington{\textquotesingle}s disease
2020 G. Birolini, M. Valenza, E. Dipaolo, E. Vezzoli, F. Talpo, C. Maniezzi, C. Caccia, V. Leoni, V.D. Bocchi, P. Conforti, E. Sogne, L. Petricca, C. Cariulo, M. Verani, A. Caricasole, A. Falqui, G.R. Biella, E. Cattaneo
Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes
2018 P. Conforti, D. Besusso, V.D. Bocchi, A. Faedo, E. Cesana, G. Rossetti, V. Ranzani, C.N. Svendsen, L.M. Thompson, M. Toselli, G. Biella, M. Pagani, E. Cattaneo
hESC-derived striatal progenitors grafted into a Huntington’s disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum
2023 R. Schellino, D. Besusso, R. Parolisi, G.B. Gómez-González, S. Dallere, L. Scaramuzza, M. Ribodino, I. Campus, P. Conforti, M. Parmar, M. Boido, E. Cattaneo, A. Buffo
hiPSCs for predictive modelling of neurodegenerative diseases : dreaming the possible
2021 P. Rivetti di Val Cervo, D. Besusso, P. Conforti, E. Cattaneo
Human cortical organoids expose a differential function of GSK3 on cortical neurogenesis
2019 A. Lopez-Tobon, C.E. Villa, C. Cheroni, S. Trattaro, N. Caporale, P. Conforti, R. Iennaco, M. Lachgar, M.T. Rigoli, B. Marco De La Cruz, P. Lo Riso, E. Tenderini, F. Troglio, M. De Simone, I. Liste-Noya, G. Macino, M. Pagani, E. Cattaneo, G. Testa
In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice
2013 P. Conforti, A. Mas Monteys, C. Zuccato, N.J. Buckley, B. Davidson, E. Cattaneo
Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington’s disease
2019 E. Vezzoli, I. Caron, F. Talpo, D. Besusso, P. Conforti, E. Battaglia, E. Sogne, A. Falqui, L. Petricca, M. Verani, P. Martufi, A. Caricasole, A. Bresciani, O. Cecchetti, P.R. Di Val Cervo, G. Sancini, O. Riess, H. Nguyen, L. Seipold, P. Saftig, G. Biella, E. Cattaneo, C. Zuccato
In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
2022 P. Conforti, V.D. Bocchi, I. Campus, L. Scaramuzza, M. Galimberti, T. Lischetti, F. Talpo, M. Pedrazzoli, A. Murgia, I. Ferrari, C. Cordiglieri, A. Fasciani, E. Arenas, D. Felsenfeld, G. Biella, D. Besusso, E. Cattaneo
Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death
2013 P. Conforti, S. Camnasio, C. Mutti, M. Valenza, M. Thompson, E. Fossale, S. Zeitlin, M.E. Macdonald, C. Zuccato, E. Cattaneo
Neural stem cells engrafted in the adult brain fuse with endogenous neurons
2013 E. Brilli, E. Reitano, L. Conti, P. Conforti, R. Gulino, G. Consalez, E. Cesana, A. Smith, F. Rossi, E. Cattaneo
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease
2012 M.A. Pouladi, E. Brillaud, Y. Xie, P. Conforti, R.K. Graham, D.E. Ehrnhoefer, S. Franciosi, W. Zhang, P. Poucheret, E. Compte, J.C. Maurel, C. Zuccato, E. Cattaneo, C. Néri, M.R. Hayden
Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation
2017 C. Cariulo, L. Azzollini, M. Verani, P. Martufi, R. Boggio, A. Chiki, S.M. Deguire, M. Cherubini, S. Gines, J. Lawrence Marsh, P. Conforti, E. Cattaneo, I. Santimone, F. Squitieri, H.A. Lashuel, L. Petricca, A. Caricasole