CONFORTI, PAOLA
CONFORTI, PAOLA
Dipartimento di Bioscienze
ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease
2021-01-01 F. Cozzolino, E. Vezzoli, C. Cheroni, D. Besusso, P. Conforti, M. Valenza, I. Iacobucci, V. Monaco, G. Birolini, M. Bombaci, A. Falqui, P. Saftig, R.L. Rossi, M. Monti, E. Cattaneo, C. Zuccato
Biphasic bioconversion of naphthalenes into dihydrodiols : solvent effects and substrate differences
2003-06-01 S. Bernasconi, F. Orsini, G.G. Sello, P. Conforti, M. Tansi, E. Galli, P. Di Gennaro, G. Bestetti
Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease : restoration by the neuroprotective compound CEP-134
2008-09-01 P. Conforti, C. Ramos, B.L. Apostol, D.A. Simmons, H.P. Nguyen, O. Riess, L.M. Thompson, C. Zuccato, E. Cattaneo
CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice
2008-09-01 B.L. Apostol, D.A. Simmons, C. Zuccato, K. Illes, J. Pallos, M. Casale, P. Conforti, C. Ramos, M. Roarke, S. Kathuria, E. Cattaneo, J.L. Marsh, L.M. Thompson
A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2
2020-10-01 D. Besusso, A. Cossu, A. Mohamed, M. Cernigoj, P. Codega, M. Galimberti, I. Campus, P. Conforti, E. Cattaneo
DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis
2020-04-16 A. Thiruvalluvan, E.P. de Mattos, J.F. Brunsting, R. Bakels, D. Serlidaki, L. Barazzuol, P. Conforti, A. Fatima, S. Koyuncu, E. Cattaneo, D. Vilchez, S. Bergink, E.H.W.G. Boddeke, S. Copray, H.H. Kampinga
Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes
2018-01-23 P. Conforti, D. Besusso, V.D. Bocchi, A. Faedo, E. Cesana, G. Rossetti, V. Ranzani, C.N. Svendsen, L.M. Thompson, M. Toselli, G. Biella, M. Pagani, E. Cattaneo
In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice
2013-06-01 P. Conforti, A. Mas Monteys, C. Zuccato, N.J. Buckley, B. Davidson, E. Cattaneo
Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington’s disease
2019-06-01 E. Vezzoli, I. Caron, F. Talpo, D. Besusso, P. Conforti, E. Battaglia, E. Sogne, A. Falqui, L. Petricca, M. Verani, P. Martufi, A. Caricasole, A. Bresciani, O. Cecchetti, P.R. Di Val Cervo, G. Sancini, O. Riess, H. Nguyen, L. Seipold, P. Saftig, G. Biella, E. Cattaneo, C. Zuccato
Investigating DNA methylation dynamics and safety of human embryonic stem cell differentiation toward striatal neurons
2015-01-01 S. Baronchelli, A. La Spada, P. Conforti, S. Redaelli, L. Dalprà, P. De Blasio, E. Cattaneo, I. Biunno
Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death
2013-02-01 P. Conforti, S. Camnasio, C. Mutti, M. Valenza, M. Thompson, E. Fossale, S. Zeitlin, M.E. Macdonald, C. Zuccato, E. Cattaneo
Neural stem cells engrafted in the adult brain fuse with endogenous neurons
2013-02-15 E. Brilli, E. Reitano, L. Conti, P. Conforti, R. Gulino, G. Consalez, E. Cesana, A. Smith, F. Rossi, E. Cattaneo
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease
2012-12-01 M.A. Pouladi, E. Brillaud, Y. Xie, P. Conforti, R.K. Graham, D.E. Ehrnhoefer, S. Franciosi, W. Zhang, P. Poucheret, E. Compte, J.C. Maurel, C. Zuccato, E. Cattaneo, C. Néri, M.R. Hayden
Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation
2017-12-12 C. Cariulo, L. Azzollini, M. Verani, P. Martufi, R. Boggio, A. Chiki, S.M. Deguire, M. Cherubini, S. Gines, J. Lawrence Marsh, P. Conforti, E. Cattaneo, I. Santimone, F. Squitieri, H.A. Lashuel, L. Petricca, A. Caricasole
Repressor element-1 silencing transcription factor (REST) is present in human control and Huntington’s disease neurones
2014-12-01 D. Schiffer, V. Caldera, M. Mellai, P. Conforti, E. Cattaneo, C. Zuccato
Rescue of gene expression by modified REST decoy oligonucleotides in a cellular model of Huntington's disease
2011-01-01 C. Soldati, A. Bithell, P. Conforti, E. Cattaneo, N.J. Buckley
SREBP2 delivery to striatal astrocytes normalizes transcription of cholesterol biosynthesis genes and ameliorates pathological features in Huntington’s Disease
2020-11-01 G. Birolini, G. Verlengia, F. Talpo, C. Maniezzi, L. Zentilin, M. Giacca, P. Conforti, C. Cordiglieri, C. Caccia, V. Leoni, F. Taroni, G. Biella, M. Simonato, E. Cattaneo, M. Valenza
Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice
2020-01-01 G. Birolini, M. Valenza, E. Di Paolo, E. Vezzoli, F. Talpo, C. Maniezzi, C. Caccia, V. Leoni, F. Taroni, V.D. Bocchi, P. Conforti, E. Sogne, L. Petricca, C. Cariulo, M. Verani, A. Caricasole, A. Falqui, G. Biella, E. Cattaneo
Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease
2008-04-01 C. Zuccato, M. Marullo, P. Conforti, M.E. MacDonald, M. Tartari, E. Cattaneo