BIROLINI, GIULIA
BIROLINI, GIULIA
Dipartimento di Bioscienze
Longitudinal and combined assessment of 24(S)-hydroxycholesterol and Neurofilament light chain in the early stages of Huntington's disease
2026 L. Sarro, M. Valenza, A. Mongelli, A. Passoni, A. Castaldo, M. Favagrossa, L. Pasetto, V. Bonetto, R. Bagnati, M. Grisoli, A. Nigri, G. Birolini, E. Zerbini, S. Tomè, M. Masseroli, E. Salvi, L. Colombo, M. Salmona, E. Cattaneo, C. Mariotti
Cholesterol nose-to-brain delivery as a possible therapeutic strategy in Huntington’s disease
2026 M. Favagrossa, A. Passoni, M. Valenza, D. Di Prisco, G. Birolini, M. Villa, A. Scolz, L. Pasetto, V. Bonetto, C. Zuccato, C. Mariotti, R. Bagnati, E. Cattaneo, L. Colombo, M. Salmona
Nanotechnological and in vivo characterization of a new generation of brain-permeable nanoparticles for brain-targeted cholesterol delivery in Huntington’s disease
2026 G. Birolini, M. Vitali, I. Ottonelli, R. Caraffi, P. Linciano, J. Thomas Duskey, C. Baraldi, B. Ruozi, M. Angela Vandelli, E. Vezzoli, G. Ceccone, F. Fumagalli, G. Tosi, E. Cattaneo, M. Valenza
Cholesterol restores corticostriatal synaptic connectivity in Huntington’s disease through BDNF/TrkB signalling, supporting a role for cholesterol pathways implicated by human genetic modifier studies
2026 A. Lenci, M. Villa, A. Scolz, G. Birolini, P. Conforti, G. Pepe, A.N. Castagno, C. Cassarino, L. Colombo, M. Favagrossa, A. Polimeno, L. Ottoboni, S. Corti, A. Di Pardo, M. Salmona, V. Maglione, C. Zuccato, E. Cattaneo
A cutting-edge approach based on UHPLC-MS to simultaneously investigate oxysterols and cholesterol precursors in biological samples: Validation in Huntington's disease mouse model
2024 A. Passoni, M. Favagrossa, M. Valenza, G. Birolini, A. Lanno, C. Mariotti, E. Cattaneo, M. Salmona, L. Colombo, R. Bagnati
The translational potential of cholesterol-based therapies for neurological disease
2023 M. Valenza, G. Birolini, E. Cattaneo
Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington's disease
2023 G. Birolini, M. Valenza, I. Ottonelli, F. Talpo, L. Minoli, A. Cappelleri, M. Bombaci, C. Caccia, C. Canevari, A. Trucco, V. Leoni, A. Passoni, M. Favagrossa, M.R. Nucera, L. Colombo, S. Paltrinieri, R. Bagnati, J.T. Duskey, R. Caraffi, M.A. Vandelli, F. Taroni, M. Salmona, E. Scanziani, G. Biella, B. Ruozi, G. Tosi, E. Cattaneo
Nanoparticles for transport across the blood-brain barrier
2022 E. Cattaneo, M. Valenza, G. Birolini, G. Tosi, B. Ruozi, F. Forni, P. Linciano, M.A. Vandelli
Cholesterol-laden brain-permeable nanoparticles support long-lasting cognitive recovery and motor amelioration in the slow-progressing zQ175DN mouse model of Huntington’s Disease
2022 G. Birolini, M. Valenza, I. Ottonelli, F. Talpo, L. Minoli, A. Cappelleri, M. Bombaci, C. Caccia, V. Leoni, A. Passoni, M. Favagrossa, M.R. Nucera, L. Colombo, S. Paltrinieri, R. Bagnati, J. Thomas Duskey, R. Caraffi, M. Angela Vandelli, F. Taroni, M. Salmona, E. Scanziani, G.R. Biella, B. Ruozi, G.F. Tosi, E. Cattaneo
CHOLESTEROL DYSFUNCTION IN HUNTINGTON¿S DISEASE: WORKING TOWARD A THERAPEUTICAL APPROACH
2021 G. Birolini
ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease
2021 F. Cozzolino, E. Vezzoli, C. Cheroni, D. Besusso, P. Conforti, M. Valenza, I. Iacobucci, V. Monaco, G. Birolini, M. Bombaci, A. Falqui, P. Saftig, R.L. Rossi, M. Monti, E. Cattaneo, C. Zuccato
SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes
2021 G. Birolini, G. Verlengia, F. Talpo, C. Maniezzi, L. Zentilin, M. Giacca, P. Conforti, C. Cordiglieri, C. Caccia, V. Leoni, F. Taroni, G. Biella, M. Simonato, E. Cattaneo, M. Valenza
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease
2021 G. Birolini, M. Valenza, I. Ottonelli, A. Passoni, M. Favagrossa, J.T. Duskey, M. Bombaci, M.A. Vandelli, L. Colombo, R. Bagnati, C. Caccia, V. Leoni, F. Taroni, F. Forni, B. Ruozi, M. Salmona, G. Tosi, E. Cattaneo
Efficacy of Cholesterol Nose-to-Brain Delivery for Brain Targeting in Huntington's Disease
2020 A. Passoni, M. Favagrossa, L. Colombo, R. Bagnati, M. Gobbi, L. Diomede, G. Birolini, E. Di Paolo, M. Valenza, E. Cattaneo, M. Salmona
Dose-dependent and disease-modifying effects of striatal infusion of cholesterol in Huntington{\textquotesingle}s disease
2020 G. Birolini, M. Valenza, E. Dipaolo, E. Vezzoli, F. Talpo, C. Maniezzi, C. Caccia, V. Leoni, V.D. Bocchi, P. Conforti, E. Sogne, L. Petricca, C. Cariulo, M. Verani, A. Caricasole, A. Falqui, G.R. Biella, E. Cattaneo
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington disease
2020 G. Birolini, M. Valenza, I. Ottonelli, A. Passoni, M. Favagrossa, J. T Duskey, M. Bombaci, M. Angela Vandelli, L. Colombo, R. Bagnati, C. Caccia, V. Leoni, F. Taroni, F. Forni, B. Ruozi, M. Salmona, G. Tosi, E. Cattaneo
SREBP2 delivery to striatal astrocytes normalizes transcription of cholesterol biosynthesis genes and ameliorates pathological features in Huntington’s Disease
2020 G. Birolini, G. Verlengia, F. Talpo, C. Maniezzi, L. Zentilin, M. Giacca, P. Conforti, C. Cordiglieri, C. Caccia, V. Leoni, F. Taroni, G. Biella, M. Simonato, E. Cattaneo, M. Valenza
Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice
2020 G. Birolini, M. Valenza, E. Di Paolo, E. Vezzoli, F. Talpo, C. Maniezzi, C. Caccia, V. Leoni, F. Taroni, V.D. Bocchi, P. Conforti, E. Sogne, L. Petricca, C. Cariulo, M. Verani, A. Caricasole, A. Falqui, G. Biella, E. Cattaneo