CATTANEO, ELENA
CATTANEO, ELENA
Dipartimento di Bioscienze
Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7
2026 C. Maffezzini, R. Iennaco, A. Scolz, S. Maestri, C. Landles, G.F. Osborne, M.M. Bronzini, C. Trovesi, T. Carzaniga, L. Casiraghi, J. Quiros Ramirez, T.F. Vogt, D.P. Felsenfeld, T. Bellini, C. Zuccato, G.P. Bates, E. Cattaneo
Longitudinal and combined assessment of 24(S)-hydroxycholesterol and Neurofilament light chain in the early stages of Huntington's disease
2026 L. Sarro, M. Valenza, A. Mongelli, A. Passoni, A. Castaldo, M. Favagrossa, L. Pasetto, V. Bonetto, R. Bagnati, M. Grisoli, A. Nigri, G. Birolini, E. Zerbini, S. Tomè, M. Masseroli, E. Salvi, L. Colombo, M. Salmona, E. Cattaneo, C. Mariotti
Cholesterol restores corticostriatal synaptic connectivity in Huntington’s disease through BDNF/TrkB signalling, supporting a role for cholesterol pathways implicated by human genetic modifier studies
2026 A. Lenci, M. Villa, A. Scolz, G. Birolini, P. Conforti, G. Pepe, A.N. Castagno, C. Cassarino, L. Colombo, M. Favagrossa, A. Polimeno, L. Ottoboni, S. Corti, A. Di Pardo, M. Salmona, V. Maglione, C. Zuccato, E. Cattaneo
Cholesterol nose-to-brain delivery as a possible therapeutic strategy in Huntington’s disease
2026 M. Favagrossa, A. Passoni, M. Valenza, D. Di Prisco, G. Birolini, M. Villa, A. Scolz, L. Pasetto, V. Bonetto, C. Zuccato, C. Mariotti, R. Bagnati, E. Cattaneo, L. Colombo, M. Salmona
Towards AI-driven prediction of HTT CAG size in super-expanded human spiny projection neurons from Huntington disease donors
2026 S. Maestri, D. Scalzo, M. Zobel, D. Besusso, E. Cattaneo
Nanotechnological and in vivo characterization of a new generation of brain-permeable nanoparticles for brain-targeted cholesterol delivery in Huntington’s disease
2026 G. Birolini, M. Vitali, I. Ottonelli, R. Caraffi, P. Linciano, J. Thomas Duskey, C. Baraldi, B. Ruozi, M. Angela Vandelli, E. Vezzoli, G. Ceccone, F. Fumagalli, G. Tosi, E. Cattaneo, M. Valenza
Transplanted human striatal progenitors exhibit functional integration and modulate host circuitry in a Huntington’s disease animal model
2025 L. Scaramuzza, M. Ribodino, C. Cassarino, M. Morrocchi, G.B. Gomez Gonzalez, R. Parolisi, E. Sozzi, G. Turrini, V. Cerrato, P. Conforti, E. Hoxha, R. Tognato, G. Galeotti, C. Cordiglieri, M.C. Crosti, S. Zucca, M. Lorenzati, S. Bovetti, P. Spaiardi, C. De'Sperati, G. Biella, L. Ottoboni, M. Parmar, S. Maestri, D. Besusso, E. Cattaneo, A. Buffo
When repetita no-longer iuvant: somatic instability of the CAG triplet in Huntington’s disease
2025 E. Cattaneo, D. Scalzo, M. Zobel, R. Iennaco, C. Maffezzini, D. Besusso, S. Maestri
A human CAGinSTEM platform for decoding HTT repeats’ somatic instability links CAG interruption to HD pathology in neurons
2025 M. Zobel, G. Damaggio, M.L. Mignogna, D. Besusso, D. Scalzo, A. Cossu, C. Trovesi, M. Crosti, F. Cortina, I. Campus, G. Formenti, S. Mazzara, F. Gregoretti, L. Antonelli, G. Oliva, C. Zuccato, V. Colonna, P. Conforti, M. Cereda, R. Lorenzo Rossi, S. Maestri, A. Scolz, R. Iennaco, E. Cattaneo
Navigating triplet repeats sequencing: concepts, methodological challenges and perspective for Huntington’s disease
2025 S. Maestri, D. Scalzo, G. Damaggio, M. Zobel, D. Besusso, E. Cattaneo
Stem Cell Revolutions: An alliance for Parkinson’s disease driven by European Commission consortia
2025 E. Cattaneo, D. Besusso
A cutting-edge approach based on UHPLC-MS to simultaneously investigate oxysterols and cholesterol precursors in biological samples: Validation in Huntington's disease mouse model
2024 A. Passoni, M. Favagrossa, M. Valenza, G. Birolini, A. Lanno, C. Mariotti, E. Cattaneo, M. Salmona, L. Colombo, R. Bagnati
Huntington’s disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids
2024 M. Galimberti, M.R. Nucera, V.D. Bocchi, P. Conforti, E. Vezzoli, M. Cereda, C. Maffezzini, R. Iennaco, A. Scolz, A. Falqui, C. Cordiglieri, M. Cremona, I. Espuny-Camacho, A. Faedo, D.P. Felsenfeld, T.F. Vogt, V. Ranzani, C. Zuccato, D. Besusso, E. Cattaneo
The translational potential of cholesterol-based therapies for neurological disease
2023 M. Valenza, G. Birolini, E. Cattaneo
hESC-derived striatal progenitors grafted into a Huntington’s disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum
2023 R. Schellino, D. Besusso, R. Parolisi, G.B. Gómez-González, S. Dallere, L. Scaramuzza, M. Ribodino, I. Campus, P. Conforti, M. Parmar, M. Boido, E. Cattaneo, A. Buffo
Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington's disease
2023 G. Birolini, M. Valenza, I. Ottonelli, F. Talpo, L. Minoli, A. Cappelleri, M. Bombaci, C. Caccia, C. Canevari, A. Trucco, V. Leoni, A. Passoni, M. Favagrossa, M.R. Nucera, L. Colombo, S. Paltrinieri, R. Bagnati, J.T. Duskey, R. Caraffi, M.A. Vandelli, F. Taroni, M. Salmona, E. Scanziani, G. Biella, B. Ruozi, G. Tosi, E. Cattaneo
In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
2022 P. Conforti, V.D. Bocchi, I. Campus, L. Scaramuzza, M. Galimberti, T. Lischetti, F. Talpo, M. Pedrazzoli, A. Murgia, I. Ferrari, C. Cordiglieri, A. Fasciani, E. Arenas, D. Felsenfeld, G. Biella, D. Besusso, E. Cattaneo
Cholesterol-laden brain-permeable nanoparticles support long-lasting cognitive recovery and motor amelioration in the slow-progressing zQ175DN mouse model of Huntington’s Disease
2022 G. Birolini, M. Valenza, I. Ottonelli, F. Talpo, L. Minoli, A. Cappelleri, M. Bombaci, C. Caccia, V. Leoni, A. Passoni, M. Favagrossa, M.R. Nucera, L. Colombo, S. Paltrinieri, R. Bagnati, J. Thomas Duskey, R. Caraffi, M. Angela Vandelli, F. Taroni, M. Salmona, E. Scanziani, G.R. Biella, B. Ruozi, G.F. Tosi, E. Cattaneo
The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities
2022 R. Iennaco, G. Formenti, C. Trovesi, R.L. Rossi, C. Zuccato, T. Lischetti, V.D. Bocchi, A. Scolz, C. Martínez-Labarga, O. Rickards, M. Pacifico, A. Crottini, A.P. Møller, R.Z. Chen, T.F. Vogt, G. Pavesi, D.S. Horner, N. Saino, E. Cattaneo
Nanoparticles for transport across the blood-brain barrier
2022 E. Cattaneo, M. Valenza, G. Birolini, G. Tosi, B. Ruozi, F. Forni, P. Linciano, M.A. Vandelli