DALLANOCE, CLELIA MARIANGIOLA LUISA
 Distribuzione geografica
Continente #
EU - Europa 9.624
NA - Nord America 7.412
AS - Asia 6.350
SA - Sud America 697
AF - Africa 188
OC - Oceania 79
Continente sconosciuto - Info sul continente non disponibili 8
Totale 24.358
Nazione #
US - Stati Uniti d'America 7.223
GB - Regno Unito 2.218
CN - Cina 2.032
IT - Italia 2.032
SG - Singapore 1.899
DE - Germania 1.820
RU - Federazione Russa 903
SE - Svezia 889
HK - Hong Kong 651
BR - Brasile 529
IN - India 471
FR - Francia 352
NL - Olanda 257
KR - Corea 251
IE - Irlanda 244
TR - Turchia 239
FI - Finlandia 169
JP - Giappone 167
UA - Ucraina 153
VN - Vietnam 146
ES - Italia 133
ID - Indonesia 121
CA - Canada 119
DK - Danimarca 116
EU - Europa 81
AU - Australia 71
CI - Costa d'Avorio 60
CH - Svizzera 50
BE - Belgio 46
CO - Colombia 46
PH - Filippine 44
AT - Austria 43
PK - Pakistan 42
IR - Iran 41
MX - Messico 41
PL - Polonia 37
TW - Taiwan 37
AR - Argentina 36
ZA - Sudafrica 34
GR - Grecia 33
BD - Bangladesh 30
EC - Ecuador 28
RO - Romania 28
IQ - Iraq 26
CL - Cile 24
MA - Marocco 21
KE - Kenya 18
MY - Malesia 18
TH - Thailandia 18
IL - Israele 17
SA - Arabia Saudita 17
UZ - Uzbekistan 17
EG - Egitto 15
CZ - Repubblica Ceca 13
NO - Norvegia 12
PT - Portogallo 11
AE - Emirati Arabi Uniti 10
HU - Ungheria 9
TN - Tunisia 9
AL - Albania 8
RS - Serbia 8
UY - Uruguay 8
BY - Bielorussia 7
JM - Giamaica 7
PE - Perù 7
PY - Paraguay 7
SC - Seychelles 7
VE - Venezuela 7
KG - Kirghizistan 6
KW - Kuwait 6
LK - Sri Lanka 6
AZ - Azerbaigian 5
BG - Bulgaria 5
BO - Bolivia 5
CM - Camerun 5
HR - Croazia 5
NG - Nigeria 5
BH - Bahrain 4
DO - Repubblica Dominicana 4
JO - Giordania 4
NZ - Nuova Zelanda 4
BA - Bosnia-Erzegovina 3
BB - Barbados 3
CR - Costa Rica 3
DZ - Algeria 3
HN - Honduras 3
LU - Lussemburgo 3
MD - Moldavia 3
MO - Macao, regione amministrativa speciale della Cina 3
OM - Oman 3
PA - Panama 3
PF - Polinesia Francese 3
SK - Slovacchia (Repubblica Slovacca) 3
TZ - Tanzania 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
BW - Botswana 2
EE - Estonia 2
GA - Gabon 2
GE - Georgia 2
Totale 24.398
Città #
Southend 1.980
Singapore 1.000
Hanover 828
Milan 723
Ashburn 717
Dallas 649
Chandler 604
Hong Kong 602
Beijing 423
Seattle 324
Princeton 302
Council Bluffs 293
Dublin 233
Wilmington 229
Munich 209
Santa Clara 192
Ann Arbor 183
Los Angeles 179
Hefei 154
Mountain View 148
Rome 141
Bengaluru 138
Fairfield 127
Dearborn 123
Redmond 113
Frankfurt am Main 111
Nanjing 109
Boardman 106
Des Moines 102
Woodbridge 101
Houston 99
Buffalo 96
Berlin 92
Jakarta 88
San Jose 80
Tokyo 77
Moscow 73
New York 73
Cambridge 69
Guangzhou 69
The Dalles 68
Redwood City 67
Barcelona 62
Jinan 61
Shanghai 61
Abidjan 60
São Paulo 59
Jacksonville 57
Sakarya 54
Columbus 53
Medford 53
Toronto 53
Somerville 52
Würzburg 50
Shenyang 49
Cangzhou 46
Ho Chi Minh City 46
Istanbul 44
Seoul 42
Tianjin 40
Andover 39
Hangzhou 39
San Diego 37
Changsha 36
Bogotá 35
Brussels 34
Serra 34
Amsterdam 32
London 31
Mumbai 31
Nanchang 31
Nuremberg 31
Brescia 30
Naples 30
Hanoi 29
Kent 29
Eitensheim 28
Zhengzhou 28
Athens 27
Hebei 27
Helsinki 27
Turin 27
Chicago 26
Stockholm 26
Denver 25
Irvine 25
Ningbo 25
Piscataway 25
Bühl 24
Phoenix 24
Fuzhou 23
San Francisco 23
Florence 22
Melbourne 22
Vienna 22
Lappeenranta 21
Quanzhou 21
Hamburg 20
Jiaxing 18
Pune 18
Totale 14.138
Nome #
HEBE project: Healthy aging versus inflamm-aging: The role of physical exercise in modulating the biomarkers of age-associated and environmentally determined chronic diseases, study protocol 582
Agonisti nicotinici selettivi nel trattamento di patologie del Sistema Nervoso Centrale 533
Epiboxidine and Novel Related Analogues : a Convenient Synthetic Approach and Estimation of Their Affinity at Neuronal Nicotinic Acetylcholine Receptor Subtypes 479
Advances in small molecule selective ligands for heteromeric nicotinic acetylcholine receptors 404
Combined treatments with the dualsteric agonist N-8-Iper plus chemotherapy drugs affect drug resistance in glioblastoma cancer stem cells 399
Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes 330
A convenient synthesis of 4-(2-hydroxyethyl)indolin-2-one, a useful intermediate for the preparation of both dopamine receptor agonists and protein kinase inhibitors 284
Chimica Analitica e Analisi Quantitativa 271
Selective agonists for M2 muscarinic receptors inhibit cell proliferation and survival in human glioblastoma cells: Possible implications in drug resistance 263
The Mechanisms Mediated by α7 Acetylcholine Nicotinic Receptors May Contribute to Peripheral Nerve Regeneration 260
Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype [Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the alpha 3 beta 4 nicotinic acetylcholine receptor subtype] 259
Photoswitchable ligands for the optical control of α7 nicotinic acetylcholine receptors: synthesis and photochromic characterization 256
The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling 250
New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: Synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations 243
Development of a direct LC-ESI-MS method for the measurement of human serum carnosinase activity 222
Novel pharmacological tools which activate mAChRs: a question of "dualsterism" 221
Orthosteric and allosteric ligands selectively acting at cholinergic receptor subtypes 221
Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors 218
Synthesis and characterization of 13C labeled carnosine derivatives for isotope dilution mass spectrometry measurements in biological matrices 217
Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl-Δ2-Isoxazoline Derivatives as Potent and Selective Agonists of α7 Nicotinic Acetylcholine Receptors 213
Novel ligands for neuronal nicotinic receptor subtypes: synthetic, pharmacological and molecular docking studies 211
Synthesis of epibatidine-related Delta(2)-isoxazoline derivatives and evaluation of their binding affinity at neuronal nicotinic acetylcholine receptors 209
The impact of Chirality on Medicinal Chemistry 208
7'-Aminonaphthazarin antibiotic derivatives 204
Synthesis of novel chiral Δ2-isoxazoline derivatives related to ABT-418 and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes 203
Iperoxo/dequalinium and W84/dequalinium hybrid ligands: synthesis, pharmacological and computational investigation at M2 mAChRs 198
(Trans)dermal delivery of opioids: a structure-permeability relationship 198
In silico design of agonists targeting the alpha7 nicotinic acetylcholine receptors, their synthesis and preliminary pharmacological evaluation 195
Dualsteric compounds modulate the signaling pattern of muscarinic M1 acetylcholine receptors 192
Synthesis and application of isotope-labeled carnosine in LCMS/MS 192
Design and synthesis of selective ligands targeting different nAChR subtypes 191
Allosteric modulation of alpha7 nicotinic receptors : mechanistic insight through metadynamics and essential dynamics 191
Chemotherapy-induced neuropathy: involvement of the alpha7 nAChR subtype 190
New spirocyclic Δ2-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors 188
Determination of acid dissociation constants of compounds active at neuronal nicotinic acetylcholine receptors by means of electrophoretic and potentiometric techniques 187
Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors 187
Alpha7 nAChR: pathogenesis and treatment of chemotherapy-induced neuropathy 187
Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity 186
The novel hybrid agonist HyNDA-1 targets the D3R-nAChR heteromeric complex in dopaminergic neurons 185
Optical control of dopamine receptors in vitro and in vivo with photoswitchable ligands 184
Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization 184
The enantiomers of epiboxidine: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes 183
Novel spirocyclic delta2-isoxazoline derivatives as lower homologues of selective agonists for neuronal alpha-7 nicotinic acetylcholine receptor subtypes 183
Novel Analgesic Agents Obtained by Molecular Hybridization of Orthosteric and Allosteric Ligands 183
Allosteric ligands for G protein-coupled receptors : a novel strategy with attractive therapeutic opportunities 182
The enantiomers of epiboxidine and of two related analogs: Synthesis and estimation of their binding affinity at α4β2 and α7 neuronal nicotinic acetylcholine receptors 182
Analgesic effects mediated by muscarinic ligands acting at both orthosteric and allosteric receptor binding sites 176
Interaction between M2 Muscarinic receptors and β-1 arrestin in gliblastoma cell lines: effects mediated by orthosteric and dualsteric agonists 175
Determination of acid dissociation constants of poorly water-soluble nicotinic ligands by means of electrophoretic and potentiometric techniques 175
Peptide derivatives and therapeutic activity thereof 174
Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation 174
Alteration of the mitochondrial activity and lipidic metabolism caused by the selective stimulation of M2 muscarinic receptors in human glioblastoma cells 171
Design of novel α7-subtype-preferring nicotinic acetylcholine receptor agonists: application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies 171
Photoswitchable ligands for light-mediated control of α7 nicotinic acetylcholine receptors: design, synthesis and photochromic characterization 171
Synthesis of enantiopure Delta(2)-isoxazoline derivatives and evaluation of their affinity and efficacy profiles at human beta-adrenergic receptor subtypes 170
Epiboxidine and Novel-Related Analogues: A Convenient Synthetic Approach and Estimation of Their at Neuronal Nicotinic Acetylcholine Receptor Subtypes 170
M2 muscarinic receptor agonists interfere with the cell proliferation and survival of human glioblastoma cancer stem cells 170
Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-Coupled Receptor 167
Modulation of the D3R-nAChR Heteromeric Complex Attenuates Nicotine Self-Administration 167
Synthesis and binding affinity at α4β2 and α7 nicotinic acetylcholine receptors of new analogs of epibatidine and epiboxidine containing the 7-azabicyclo[2.2.1]hept-2-ene ring system 166
Synthesis of new Delta(2)-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists 166
Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study 166
Lactam Enolate-Pyridone Addition : Synthesis of 4-Halocytisines 164
Activation of M2 muscarinic acetylcholine receptors by orthosteric and dualsteric agonists in glioblastoma cancer stem cells: effects on cell proliferation and drug resistance 164
Identification of novel potential B4GALT6 inhibitors through a large scale virtual screening 163
Dualsteric activation of M2 muscarinic acetylcholine receptors inhibits cell proliferation in human glioblastoma cell lines 163
Tacrine/Xanomeline hybrid ligands: synthesis and pharmacological evaluation at M1 muscarinic acetylcholine receptors and acetylcholinesterases 162
Nuovi ligandi nicotinici correlati all'Epibatidina e all'Epibossidina: sintesi e valutazione della loro affinità per i recettori nicotinici neuronali alpha4beta2 e alpha7 159
Design, synthesis and preliminary biological evaluation of 3-cyclopropyl-4-phenoxy-1H-pyrazole derivatives as small molecular ligands of RAGE 156
Novel bicylic delta2-isoxazoline and 3-oxo-isoxazolidine derivatives : synthesis and binding affinity at neuronal nicotinic receptor subtypes 155
Nicotinic anti-inflammatory pathway: a new target to control low-grade inflammation and glucose homeostasis in obesity 155
Synthesis and pharmacological characterization of new analogs of broxaterol 154
Synthesis of novel epibatidine-related derivatives through 1,3-dipolar cycloaddition of pyridinenitrile oxides 153
Nicotinic agonists selective for the Alpha7 Receptor Subtype, the process for their preparation thereof and pharmaceutical compositions therefrom 152
New Hybrid and Mutant PIA and MII Toxins with Greater Affinty and Selectivity for the A6* Subtype 151
Targeting the D3R-nAChR heteromeric complex for nicotine cessation 150
G protein inhibitors unravel Gq-dependent adenylyl cyclase activation in CHO-M1 cells 150
Progettazione e sintesi di analoghi strutturali dell’Epibossodina 149
New hybrid muscarinic agonists: in vitro functional characterization and in vivo analgesic activity evaluation 149
Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor 148
Novel quinuclidine derivatives to investigate the alpha-7 nicotinic acetylcholine receptor activation: new insight and perspectives 147
Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation 147
The Combined Treatment with Chemotherapeutic Agents and the Dualsteric Muscarinic Agonist Iper-8-Naphthalimide Affects Drug Resistance in Glioblastoma Stem Cells 146
A chemoenzymatic approach to the synthesis of the stereoisomers of a beta-adrenergic receptor antagonist 145
Pharmacological profile of enantiomerically pure chiral muscarinic agonists - Desoxymuscarines 144
SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF STEREOISOMERIC MUSCARINES 144
A Photoactivatable Version of Ivabradine Enables Light-Induced Block of HCN Current In Vivo 142
Novel Bifunctional Compounds Targeting Nicotine and Dopamine Receptor Subtypes: Synthesis and Pharmacological Investigation 142
Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells 142
Design, synthesis and pharmacological properties of alkylbisammonio bitopic ligands of muscarinic acetylcholine receptors 140
Novel chiral isoxazole derivatives: synthesis and pharmacological characterization at human b-adrenergic receptor subtypes 138
Chemoenzymatic synthesis of the enantiomers of desoxymuscarine 138
Transdermal delivery of morphine derivatives : a qualitative structure/in vitro permeability relationship 137
Selective nicotinic agonists to treat pathologies of the central nervous system 136
Stable desensitization of α7 nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site 136
Semisynthetic derivatives of purpuromycin as potential topical agents for vaginal infections 135
Alpha7 nicotinic acetylcholine receptor silent agonists: exploration of the SAR for NS6740 133
Enzymatic resolution of 3-butene-1,2-diol in organic solvents and optimization of reaction conditions 132
Transdermal delivery of morphine derivatives : a qualitative structure-in vitro permeability relationship 132
Synthesis of a group of novel Xanomeline/77-LH-28-1 hybrid ligands and their FRET investigation at muscarinic acetylcholine receptor subtypes 132
Totale 19.422
Categoria #
all - tutte 72.697
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.697


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021971 0 0 0 0 0 142 58 106 144 132 284 105
2021/20222.860 189 91 98 135 174 469 547 148 174 195 210 430
2022/20232.538 335 228 240 287 242 440 83 191 207 59 136 90
2023/20241.857 62 125 74 83 394 166 129 120 101 125 242 236
2024/20254.624 176 417 179 427 388 240 184 486 218 348 675 886
2025/20265.127 874 682 1.289 754 848 680 0 0 0 0 0 0
Totale 25.666