RUFFONI, ALESSANDRO
RUFFONI, ALESSANDRO
Dipartimento di Scienze Farmaceutiche
Self-assembled hydrophobic Ala-Aib peptide encapsulating curcumin: a convenient system for water insoluble drugs
2020 S. Locarno, S. Argentiere, A. Ruffoni, D. Maggioni, R. Soave, R. Bucci, E. Erba, C. Lenardi, M.L. Gelmi, F. Clerici
Identification of the first enantiopure Rac1–Tiam1 protein–protein interaction inhibitor and its optimized synthesis via phosphine free remote group directed hydroarylation
2019 A. Ruffoni, N. Ferri, A. Pinto, S. Pellegrino, A. Contini, F. Clerici
Aqueous self-assembly of short hydrophobic peptides containing norbornene amino acid into supramolecular structures with spherical shape
2016 A. Ruffoni, M.V. Cavanna, S. Argentiere, S. Locarno, S. Pellegrino, M.L. Gelmi, F. Clerici
Spherical shape supramolecular structure of serum stable self- assembled pentapeptides containing the constrained norbornene amino acid
2015 F. Clerici, M. Zuccolo, A. Ruffoni, M.V. Cavanna, S. Argentiere
Model peptides containing the 3-sulfanylnorbornene amino acid, a conformationally constrained cysteine analogue effective inducer of 3(10)-helix secondary structures
2015 A. Ruffoni, A. Contini, R. Soave, L. Lo Presti, I. Esposto, I. Maffucci, D. Nava, S. Pellegrino, M.L. Gelmi, F. Clerici
SYNTHESIS OF NEW CONFORMATIONALLY CONSTRAINED BETA-SULFANYL-ALFA- AMINO ACIDS AND THEIR EXPLOITATION IN THE SYNTHESIS OF PEPTIDOMIMETICS
2014 A. Ruffoni
2-Amino-3-(phenylsulfanyl)norbornane-2-carboxylate : an Appealing Scaffold for the Design of Rac1-Tiam1 Protein-Protein Interaction Inhibitors
2014 A. Ruffoni, N. Ferri, S.K. Bernini, C. Ricci, A. Corsini, I. Maffucci, F. Clerici, A. Contini
Disegno, sintesi e valutazione farmacologica di nuovi inibitori della proteina Rac1
2013 A. Ruffoni, F. Clerici, A. Contini, N. Ferri
Direct synthesis of fluorinated heteroarylether bioisosteres
2013 Q. Zhou, A. Ruffoni, R. Gianatassio, Y. Fujiwara, E. Sella, D. Shabat, P.S. Baran
Design, synthesis and pharmacological evaluation of new Rac1 protein inhibitors
2013 A. Ruffoni, F. Clerici, A. Contini, N. Ferri
Sulfanyl-methylene-5(4H)-oxazolones and β-sulfanyl-α-nitroacrylates as appealing dienophiles for the synthesis of conformationally constrained cysteine analogues
2012 A. Ruffoni, A. Casoni, S. Pellegrino, M.L. Gelmi, R. Soave, F. Clerici
Hydroarylation of substituted norbornene amino acids : studies on long-range stereo-electronic effects on the regioselectivity of the addition
2012 A. Ruffoni, A. Casoni, M.L. Gelmi, S. Pellegrino, F. Clerici
Differenti approcci sintetici di beta-(FENILTIO)-NORBORNAN-2-AMMINOESTERI sostituiti
2010 A. Ruffoni, A. Casoni, F. Clerici