BOLCHI, CRISTIANO
 Distribuzione geografica
Continente #
EU - Europa 6.200
NA - Nord America 3.224
AS - Asia 1.729
SA - Sud America 84
AF - Africa 15
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 7
Totale 11.271
Nazione #
US - Stati Uniti d'America 3.139
GB - Regno Unito 2.014
IT - Italia 1.260
DE - Germania 1.180
CN - Cina 863
SE - Svezia 547
FR - Francia 272
IN - India 256
TR - Turchia 155
IE - Irlanda 152
KR - Corea 148
RU - Federazione Russa 146
UA - Ucraina 145
DK - Danimarca 114
FI - Finlandia 88
NL - Olanda 80
HK - Hong Kong 79
SG - Singapore 66
EU - Europa 65
CA - Canada 56
BE - Belgio 37
CO - Colombia 34
ES - Italia 30
CH - Svizzera 29
PH - Filippine 29
JP - Giappone 28
BR - Brasile 27
MX - Messico 25
GR - Grecia 24
PL - Polonia 18
VN - Vietnam 17
ID - Indonesia 16
HU - Ungheria 15
SA - Arabia Saudita 15
AU - Australia 11
PT - Portogallo 9
TH - Thailandia 9
AR - Argentina 8
IL - Israele 8
PE - Perù 8
LT - Lituania 7
RO - Romania 7
SC - Seychelles 6
CL - Cile 5
JO - Giordania 5
MY - Malesia 5
IR - Iran 4
NO - Norvegia 4
RS - Serbia 4
SI - Slovenia 4
AM - Armenia 3
EG - Egitto 3
HR - Croazia 3
KZ - Kazakistan 3
MO - Macao, regione amministrativa speciale della Cina 3
PK - Pakistan 3
TN - Tunisia 3
TW - Taiwan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AT - Austria 2
BG - Bulgaria 2
EC - Ecuador 2
KE - Kenya 2
KW - Kuwait 2
LI - Liechtenstein 2
PS - Palestinian Territory 2
UZ - Uzbekistan 2
A1 - Anonimo 1
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BD - Bangladesh 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
CZ - Repubblica Ceca 1
GE - Georgia 1
GT - Guatemala 1
LU - Lussemburgo 1
MK - Macedonia 1
MT - Malta 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PR - Porto Rico 1
SK - Slovacchia (Repubblica Slovacca) 1
TT - Trinidad e Tobago 1
Totale 11.332
Città #
Southend 1.835
Chandler 555
Hanover 523
Milan 514
Ann Arbor 190
Princeton 189
Beijing 185
Ashburn 184
Seattle 162
Dublin 148
Wilmington 141
Fairfield 135
Mountain View 118
Dearborn 108
Jacksonville 89
Nanjing 87
Redmond 72
Bengaluru 69
Des Moines 68
Woodbridge 67
Houston 65
Hong Kong 61
Munich 54
Boardman 53
Phoenix 49
Seoul 49
Toronto 49
Andover 43
Cambridge 43
Redwood City 41
Shanghai 40
Shenyang 39
Frankfurt am Main 38
Sakarya 38
Somerville 38
Serra 37
Brussels 36
Bogotá 34
Petina 34
Berlin 33
Guangzhou 33
Istanbul 33
Jinan 30
Rome 30
Nanchang 29
Groningen 28
Helsinki 27
San Diego 27
Kiez 24
Changsha 23
Hebei 23
Kent 23
Bühl 22
Mumbai 22
New York 22
Nürnberg 22
Hangzhou 19
Monza 19
Athens 18
Sunnyvale 18
Tianjin 16
Budapest 15
Medford 15
Ningbo 15
Riyadh 15
Singapore 15
London 14
Odernheim 14
Auburn Hills 13
Bologna 13
Dong Ket 12
Hamburg 12
Los Angeles 12
Rho 12
San Jose 12
Turin 12
Mozzate 11
Pavia 11
Jiaxing 10
Varedo 10
Bangalore 9
Pune 9
Tokyo 9
Zurich 9
Bitonto 8
Catania 8
Chicago 8
Chongqing 8
Cinisello Balsamo 8
Desio 8
Geisenheim 8
Hefei 8
Krakow 8
Kunming 8
Nuremberg 8
Pioltello 8
São Paulo 8
Tappahannock 8
Zhengzhou 8
Bangkok 7
Totale 7.227
Nome #
Synthesis and alpha4beta2 nicotinic affinity of 2-pyrrolidinylmethoxyimines and prolinal oxime ethers 473
ANALOGHI STRUTTURALI DEL WB 4101: PROGETTAZIONE, SINTESI E VALUTAZIONE BIOLOGICA 353
A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro" 299
Ten years of fentanyl-like drugs: A technical-analytical review 288
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9- nicotinic ligands on glioblastoma cells 261
Benzodioxane–benzamides as new bacterial cell division inhibitors 213
Structure–affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of α1 antagonist WB-4101 205
Determination of Methyldibromoglutaronitrile (MDBGN) in Skin Care Products by Gaschromatography-Mass Spectrometry Employing an Enhanced Matrix Removal (EMR) Lipid Clean-Up 198
Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist 193
Processo di risoluzione di 2-ossazolidinoni racemici 190
Resolution of 5-hydroxymethyl-2-oxazolidinone by preferential crystallization[ 1 ] and investigations on the nature of the racemates of some 2-oxazolidinone derivatives 187
3-(Benzodioxan-2-ylmethoxy)-2,6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and Mtb cell division 177
Development and Early Identification of Cannabis Chemotypes during the Plant Growth: Current Analytical and Chemometric Approaches 176
1H NMR spectroscopy in the presence of Mosher acid to rapidly determine the enantiomeric composition of amino acid benzyl esters, chirons susceptible to easy racemization 174
QSAR study for a novel series of ortho monosubstituted phenoxy analogues of alpha(1)-adrenoceptor antagonist WB4101 172
Chemistry and pharmacology of a series of unichiral analogues of 2-(2-pyrrolidinyl)-1,4-benzodioxane, prolinol phenyl ether and prolinol 3-pyridyl ether designed as alpha4beta2-nicotinic acetylcholine receptor agonists 170
Univocal syntheses of 2- and 3-hydroxymethyl-2,3-dihydro[1,4]dioxino[2,3-b]pyridine enantiomers 169
A short entry to enantiopure 2-substituted 1,4-benzodioxanes by efficient resolution methods 168
Processo di risoluzione di un sale della carnitinammide 168
1,4-Benzodioxane, an evergreen, versatile scaffold in medicinal chemistry : a review of its recent applications in drug design 162
Influence of (S)-1-phenylethylamine para substitution on the resolution of (±)-1,4-benzodioxane-2-carboxylic acid: a crystallographic, theoretical and morphologic approach 160
Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan 160
Behavioural and pharmacological profiles of zebrafish administrated pyrrolidinyl benzodioxanes and prolinol aryl ethers with high affinity for heteromeric nicotinic acetylcholine receptors 157
One-step preparation of enantiopure L- or D-amino acid benzyl esters avoiding the use of banned solvents 155
Analisi farmaceutica 150
Synthesis and alpha 4 beta 2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes 149
A highly efficient method for the alpha,beta-dehydrogenation of alpha-amino esters and alpha-amino-beta-diesters 146
Synthesis and a4b2 nicotinic affinity of the stereoisomers of 2-(1-methyl-2-pyrrolidinyl)-1,4-benzodioxane and of its nor-methyl derivative 145
QSAR study for a novel series of ortho disubstituted phenoxy analogues of a1-adrenoceptor antagonist WB4101 143
Highly efficient resolutions of 1,4-benzodioxane-2-carboxylic acid with para substituted 1-phenylethylamines 142
ANALOGUES OF ALPHA1-ADRENOCEPTOR ANTAGONIST WB4101: DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION 141
Nicotinic receptors increase cell proliferation and tumour progression in non-small cell lung cancer cell line 139
6‑Methoxy-7-benzofuranoxy and 6‑Methoxy-7-indolyloxy Analogues of 2‑[2-(2,6-Dimethoxyphenoxy)ethyl]aminomethyl-1,4- benzodioxane (WB4101) : 1 Discovery of a Potent and Selective α1D Adrenoceptor Antagonist 138
WB4101-related compounds: New, subtype-selective alpha(1)-adrenoreceptor antagonists (or inverse agonists?) 137
alpha9- and alpha7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line 135
SYNTHESIS AND BINDING AFFINITY OF NEW HIGHLY SELECTIVE alpha4beta2 NICOTINIC LIGANDS 133
SYNTHESIS AND BINDING AFFINITY OF NEW HIGHLY SELECTIVE alpha4beta2 NICOTINIC LIGANDS 131
Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase 130
A simple route to synthesize (E)-3 propyl-4-oxo-2-butenoic acid esters through the Z isomer 129
Characterization of chemotype-dependent terpenoids profile in cannabis by headspace gas-chromatography coupled to time-of-flight mass spectrometry 129
Resolution of 1-phenyl-2-( p-tolyl)ethylamine via diastereomeric salt formation 128
Heteroaryl carnosine analogues: design, synthesis and carbonyl quenching activity 128
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NON-PEPTIDIC INHIBITORS OF FARNEYLTRANSFRERASE 127
The use of the naphthyl probe to scan the alpha-1A/5HT1A receptor binding sites: discovery of novel alpha-1A selective antagonists 126
Unichiral 2-(2′-Pyrrolidinyl)-1,4-benzodioxanes : the 2R,2′S Diastereomer of the N-Methyl-7-hydroxy Analogue Is a Potent α4β2- and α6β2-Nicotinic Acetylcholine Receptor Partial Agonist 125
Analytical, computational and formulation studies on TPGS as P-gp inhibitor 124
Simple process for the preparation of cetyltrimethylammonium naproxenate (naprocet) 123
Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype 122
Farnesyltransferase inhibitors : CAAX mimetics based on different biaryl scaffolds 121
Resolution of 2-substituted 1,4-benzodioxanes by entrainment 120
From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at alpha4beta2 nicotinic acetylcholine receptor 114
Influence of ionization state on the activation of temocapril by hCES1: a molecular-dynamics study 113
Activation of abungarotoxin-sensitive nicotinic receptors in non small cell lung cancer A459 plays an important role in nicotine-induced proliferation 113
Design, synthesis and binding affinity of acetylcholine carbamoyl analogues 109
Entrainment resolution of carnitinamide chloride 106
SEARCH FOR SELECTIVE ANTAGONISTS AT α1-ADRENORECEPTOR SUBTYPES: WB-4101 RELATED COMPOUNDS 106
From 2-aminomethyl-1,4-benzodioxane enantiomers to unichiral 2-cyano- and 2-carbonyl-substituted benzodioxanes via dichloroamine 106
Diastereomeric 2-aminomethyl-1,4-benzodioxane mandelates : phase diagrams and resolution 104
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 104
One-pot racemization process of 1-phenyl-1,2,3,4-tetrahydroisoquinoline : a key intermediate for the antimuscarinic agent solifenacin 103
Enantiomer systems of carnitinamide inorganic salts: introductory studies to a successful entrainment resolution 99
Modelling of full-length human α4β2 nicotinic receptor by fragmental approach and analysis of its binding modes 98
Efficient conversion of d-mannitol into 1,2:5,6-diacetonide with Aquivion-H as a recyclable catalyst 98
Highly efficient racemisation of a key intermediate of the antibiotic moxifloxacin 94
Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S-prolinol as α4β2-nicotinic acetylcholine receptor ligands 94
Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency 91
Structure Activity Relationship of novel antimicrobial agents, acting as inhibitors of the bacterial cell division protein Ftsz 88
Enantiomerically Pure Dibenzyl Esters of L‑Aspartic and L‑Glutamic Acid 87
Preparation and unequivocal identification of the regioisomers of nitrocatechol monobenzyl ether 87
Predicting the physicochemical profile of diastereoisomeric histidine-containing dipeptides by property space analysis 83
4-, 5-, 6-, and 7-Hydroxybenzofuran: a unified strategy for a two-step synthesis of versatile benzofuranic building blocks 81
Determinants for α4β2 vs. α3β4 Subtype Selectivity of Pyrrolidine-Based nAChRs Ligands: A Computational Perspective with Focus on Recent cryo-EM Receptor Structures [Determinants for alpha 4 beta 2 vs. alpha 3 beta 4 Subtype Selectivity of Pyrrolidine-Based nAChRs Ligands: A Computational Perspective with Focus on Recent cryo-EM Receptor Structures] 80
Crystallization-based resolution of 1,4-benzodioxane-2-carboxylic acid enantiomers via diastereomeric 1-phenylethylamides 78
Novel inhibitors of the bacterial cell division protein FtsZ: synthesis and antibacterial activity 78
Green Oxidation of Ketones to Lactones with Oxone in Water 78
Efficient One-Pot Reductive Aminations of Carbonyl Compounds with Aquivion-Fe as a Recyclable Catalyst and Sodium Borohydride 77
Antihypertensive phytocomplexes of proven efficacy and weel-established use: mode of action and individual characterization of the active constituents 76
Medicinal Cannabis: Extended Stability of Cannabis Extracts Produced Using a New Ethanol-based Extraction Method 75
Highly efficient resolutions with isopropylidene glycerol 3-carboxy-2-naphthoate 75
Preparation of enantiopure methionine, arginine, tryptophan, and proline benzyl esters in green ethers by Fischer–Speier reaction 73
Synthesis of α-Hydroxy Fatty Acids from Fatty Acids by Intermediate α-Chlorination with TCCA under Solvent-Free Conditions: A Way to Valorization of Waste Fat Biomasses 73
From carnitinamide to 5-aminomethyl-2-oxazolidinones 69
New Ras CAAX mimetics : design, synthesis, antiproliferative activity, and RAS prenylation inhibition 63
ENANTIOPURI, senza usare solventi ‘HH’ 63
Design of a H₂O₂-generating P450SPα fusion protein for high yield fatty acid conversion 63
Phase Diagrams to Evaluate the Opportunity for Enantiomeric Enrichment of Some Nonracemic Mixtures of Amino Acid Benzyl Esters by Crystallization as p-Toluenesulfonate Salts 62
Castanea sativa Mill. bark extract cardiovascular effects in a rat model of high‐fat diet 62
HETEROARYLOXY ANALOGUES OF WB4101: SYNTHESIS AND BIOLOGICAL EVALUATION AT ALPHA-1-ADRENOCEPTOR SUBTYPES 61
From 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) to Selective Small-Molecule Antagonists of Human α9α10 Nicotinic Receptor by Modifications at the Ammonium Ethyl Residue [From 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) to Selective Small-Molecule Antagonists of Human alpha 9 alpha 10 Nicotinic Receptor by Modifications at the Ammonium Ethyl Residue] 54
Fractioning and Compared 1H NMR and GC-MS Analyses of Lanolin Acid Components 43
Pyrrolidinyl benzofurans and benzodioxanes: Selective α4β2 nicotinic acetylcholine receptor ligands with different activity profiles at the two receptor stoichiometries 39
The Antioxidant Role of Hemp Phytocomplex in Cannabis Oil-Based Extracts 34
Subnanomolar Affinity and Selective Antagonism at α7 Nicotinic Receptor by Combined Modifications of 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) 31
Design of a photo-activatable ivabradine to enable light induced block of HCN current in tissues 31
Small molecule ligands for α9 * and α7 nicotinic receptors: A survey and an update, respectively 26
Selective potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor response by NS9283 analogues 23
Methyl 8- and 5-Bromo-1,4-Benzodioxane-2-carboxylate: Unambiguous Identification of the Two Regioisomers 21
Methyl 8- and 5-Nitro-1,4-Benzodioxane-2-Carboxylate 20
Sustainable Routes for Wool Grease Removal Using Green Solvent Cyclopentyl Methyl Ether in Solvent Extraction and Biosurfactant Wool Protein Hydrolyzate in Scouring 20
Green Oxidation of Heterocyclic Ketones with Oxone in Water 19
Totale 12.134
Categoria #
all - tutte 30.565
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.565


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019194 0 0 0 0 0 0 0 0 0 0 92 102
2019/20201.477 133 76 41 109 98 159 200 98 212 187 82 82
2020/20211.202 63 130 82 56 152 81 83 118 95 91 178 73
2021/20221.931 127 51 39 74 144 136 503 97 204 134 125 297
2022/20231.986 271 239 198 185 202 303 72 141 185 38 89 63
2023/20241.336 73 106 95 136 291 133 88 166 63 145 40 0
Totale 12.168