IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca

BOLCHI, CRISTIANO
 Distribuzione geografica
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Continente #
EU - Europa 8.222
NA - Nord America 6.591
AS - Asia 6.355
SA - Sud America 643
AF - Africa 155
OC - Oceania 43
Continente sconosciuto - Info sul continente non disponibili 9
Totale 22.018
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Nazione #
US - Stati Uniti d'America 6.346
GB - Regno Unito 2.125
CN - Cina 2.061
IT - Italia 1.771
SG - Singapore 1.769
DE - Germania 1.381
SE - Svezia 564
RU - Federazione Russa 536
FR - Francia 515
HK - Hong Kong 495
BR - Brasile 465
VN - Vietnam 391
IN - India 388
BD - Bangladesh 345
NL - Olanda 303
KR - Corea 205
TR - Turchia 188
IE - Irlanda 160
FI - Finlandia 158
UA - Ucraina 156
DK - Danimarca 125
CA - Canada 120
JP - Giappone 117
ID - Indonesia 87
PL - Polonia 80
MX - Messico 79
CI - Costa d'Avorio 68
ES - Italia 68
EU - Europa 65
AR - Argentina 57
BE - Belgio 47
CO - Colombia 45
PH - Filippine 45
AU - Australia 39
GR - Grecia 34
PK - Pakistan 33
PT - Portogallo 33
CH - Svizzera 30
IQ - Iraq 28
EC - Ecuador 25
SA - Arabia Saudita 25
ZA - Sudafrica 24
AT - Austria 23
UZ - Uzbekistan 23
HU - Ungheria 22
CL - Cile 16
IL - Israele 16
TH - Thailandia 16
TW - Taiwan 16
MY - Malesia 14
VE - Venezuela 14
EG - Egitto 13
JO - Giordania 13
KZ - Kazakistan 13
LT - Lituania 13
TN - Tunisia 11
RS - Serbia 10
CZ - Repubblica Ceca 9
JM - Giamaica 9
MA - Marocco 9
PE - Perù 9
AZ - Azerbaigian 8
IR - Iran 8
RO - Romania 8
AE - Emirati Arabi Uniti 7
KE - Kenya 7
BG - Bulgaria 6
NO - Norvegia 6
PY - Paraguay 6
SC - Seychelles 6
SI - Slovenia 6
TT - Trinidad e Tobago 6
AM - Armenia 5
LV - Lettonia 5
MT - Malta 5
NI - Nicaragua 5
NP - Nepal 5
AL - Albania 4
CM - Camerun 4
CR - Costa Rica 4
GT - Guatemala 4
HR - Croazia 4
KG - Kirghizistan 4
KH - Cambogia 4
LB - Libano 4
LU - Lussemburgo 4
PS - Palestinian Territory 4
BO - Bolivia 3
BY - Bielorussia 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
LI - Liechtenstein 3
MO - Macao, regione amministrativa speciale della Cina 3
NZ - Nuova Zelanda 3
OM - Oman 3
SV - El Salvador 3
UY - Uruguay 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BH - Bahrain 2
DZ - Algeria 2
Totale 22.040
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Città #
Southend 1.835
Singapore 995
Ashburn 790
Milan 662
Chandler 555
Hanover 523
Hong Kong 444
San Jose 414
Beijing 382
Dallas 277
Council Bluffs 258
Santa Clara 242
Ann Arbor 190
Princeton 189
Seattle 169
Dublin 154
Los Angeles 151
Wilmington 142
Des Moines 136
Fairfield 136
New York 134
Hefei 132
Ho Chi Minh City 125
Bengaluru 121
Mountain View 118
Frankfurt am Main 113
Dearborn 108
Hanoi 107
Lauterbourg 106
Guangzhou 104
Buffalo 102
Jacksonville 92
Munich 92
Moscow 90
Nanjing 89
Seoul 85
Houston 80
Tokyo 76
Shanghai 75
Redmond 72
Phoenix 69
The Dalles 68
Abidjan 67
Woodbridge 67
Helsinki 65
Toronto 64
Boardman 62
Rome 58
Jakarta 57
Columbus 54
Istanbul 51
São Paulo 45
Andover 43
Cambridge 43
Shenyang 43
Berlin 42
Redwood City 41
Brussels 40
Changsha 40
Bogotá 39
Naples 38
Sakarya 38
Somerville 38
Cangzhou 37
Serra 37
Petina 34
Jinan 33
Tianjin 33
Nanchang 32
Kent 31
London 31
Mumbai 30
Groningen 29
Nuremberg 29
San Diego 29
Hangzhou 28
Chicago 27
Athens 24
Kiez 24
Lappeenranta 24
Hebei 23
North Charleston 23
Wroclaw 23
Bühl 22
Fuzhou 22
Monza 22
Nürnberg 22
Shenzhen 22
Turin 22
Warsaw 22
Belo Horizonte 20
Budapest 20
Wuhan 20
Düsseldorf 19
Mexico City 19
Orem 19
Riyadh 19
Atlanta 18
Montreal 18
Sunnyvale 18
Totale 12.762
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Nome #
Synthesis and alpha4beta2 nicotinic affinity of 2-pyrrolidinylmethoxyimines and prolinal oxime ethers 561
ANALOGHI STRUTTURALI DEL WB 4101: PROGETTAZIONE, SINTESI E VALUTAZIONE BIOLOGICA 471
Medicinal Cannabis: Extended Stability of Cannabis Extracts Produced Using a New Ethanol-based Extraction Method 453
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9- nicotinic ligands on glioblastoma cells 422
A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro" 413
Ten years of fentanyl-like drugs: A technical-analytical review 389
Characterization of chemotype-dependent terpenoids profile in cannabis by headspace gas-chromatography coupled to time-of-flight mass spectrometry 368
Development and Early Identification of Cannabis Chemotypes during the Plant Growth: Current Analytical and Chemometric Approaches 343
Selective potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor response by NS9283 analogues 306
Determination of Methyldibromoglutaronitrile (MDBGN) in Skin Care Products by Gaschromatography-Mass Spectrometry Employing an Enhanced Matrix Removal (EMR) Lipid Clean-Up 305
1,4-Benzodioxane, an evergreen, versatile scaffold in medicinal chemistry : a review of its recent applications in drug design 304
Structure–affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of α1 antagonist WB-4101 302
Chemistry and pharmacology of a series of unichiral analogues of 2-(2-pyrrolidinyl)-1,4-benzodioxane, prolinol phenyl ether and prolinol 3-pyridyl ether designed as alpha4beta2-nicotinic acetylcholine receptor agonists 302
Benzodioxane–benzamides as new bacterial cell division inhibitors 302
Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan 296
3-(Benzodioxan-2-ylmethoxy)-2,6-difluorobenzamides bearing hydrophobic substituents at the 7-position of the benzodioxane nucleus potently inhibit methicillin-resistant Sa and Mtb cell division 284
QSAR study for a novel series of ortho monosubstituted phenoxy analogues of alpha(1)-adrenoceptor antagonist WB4101 282
Behavioural and pharmacological profiles of zebrafish administrated pyrrolidinyl benzodioxanes and prolinol aryl ethers with high affinity for heteromeric nicotinic acetylcholine receptors 281
Resolution of 5-hydroxymethyl-2-oxazolidinone by preferential crystallization[ 1 ] and investigations on the nature of the racemates of some 2-oxazolidinone derivatives 280
1H NMR spectroscopy in the presence of Mosher acid to rapidly determine the enantiomeric composition of amino acid benzyl esters, chirons susceptible to easy racemization 279
Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist 270
One-step preparation of enantiopure L- or D-amino acid benzyl esters avoiding the use of banned solvents 268
Processo di risoluzione di 2-ossazolidinoni racemici 247
ANALOGUES OF ALPHA1-ADRENOCEPTOR ANTAGONIST WB4101: DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION 247
Univocal syntheses of 2- and 3-hydroxymethyl-2,3-dihydro[1,4]dioxino[2,3-b]pyridine enantiomers 245
A short entry to enantiopure 2-substituted 1,4-benzodioxanes by efficient resolution methods 244
Nicotinic receptors increase cell proliferation and tumour progression in non-small cell lung cancer cell line 243
alpha9- and alpha7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line 241
4-, 5-, 6-, and 7-Hydroxybenzofuran: a unified strategy for a two-step synthesis of versatile benzofuranic building blocks 240
Processo di risoluzione di un sale della carnitinammide 236
Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype 234
Highly efficient resolutions of 1,4-benzodioxane-2-carboxylic acid with para substituted 1-phenylethylamines 231
Influence of (S)-1-phenylethylamine para substitution on the resolution of (±)-1,4-benzodioxane-2-carboxylic acid: a crystallographic, theoretical and morphologic approach 227
QSAR study for a novel series of ortho disubstituted phenoxy analogues of a1-adrenoceptor antagonist WB4101 227
Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase 226
From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at alpha4beta2 nicotinic acetylcholine receptor 219
Influence of ionization state on the activation of temocapril by hCES1: a molecular-dynamics study 218
Synthesis and a4b2 nicotinic affinity of the stereoisomers of 2-(1-methyl-2-pyrrolidinyl)-1,4-benzodioxane and of its nor-methyl derivative 218
SYNTHESIS AND BINDING AFFINITY OF NEW HIGHLY SELECTIVE alpha4beta2 NICOTINIC LIGANDS 218
Heteroaryl carnosine analogues: design, synthesis and carbonyl quenching activity 216
SYNTHESIS AND BINDING AFFINITY OF NEW HIGHLY SELECTIVE alpha4beta2 NICOTINIC LIGANDS 215
Analisi farmaceutica 215
Resolution of 1-phenyl-2-( p-tolyl)ethylamine via diastereomeric salt formation 211
Unichiral 2-(2′-Pyrrolidinyl)-1,4-benzodioxanes : the 2R,2′S Diastereomer of the N-Methyl-7-hydroxy Analogue Is a Potent α4β2- and α6β2-Nicotinic Acetylcholine Receptor Partial Agonist 211
SEARCH FOR SELECTIVE ANTAGONISTS AT α1-ADRENORECEPTOR SUBTYPES: WB-4101 RELATED COMPOUNDS 210
Activation of abungarotoxin-sensitive nicotinic receptors in non small cell lung cancer A459 plays an important role in nicotine-induced proliferation 209
6‑Methoxy-7-benzofuranoxy and 6‑Methoxy-7-indolyloxy Analogues of 2‑[2-(2,6-Dimethoxyphenoxy)ethyl]aminomethyl-1,4- benzodioxane (WB4101) : 1 Discovery of a Potent and Selective α1D Adrenoceptor Antagonist 207
The use of the naphthyl probe to scan the alpha-1A/5HT1A receptor binding sites: discovery of novel alpha-1A selective antagonists 205
Efficient One-Pot Reductive Aminations of Carbonyl Compounds with Aquivion-Fe as a Recyclable Catalyst and Sodium Borohydride 205
Synthesis and alpha 4 beta 2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes 203
Farnesyltransferase inhibitors : CAAX mimetics based on different biaryl scaffolds 203
Structure Activity Relationship of novel antimicrobial agents, acting as inhibitors of the bacterial cell division protein Ftsz 203
Efficient conversion of d-mannitol into 1,2:5,6-diacetonide with Aquivion-H as a recyclable catalyst 203
WB4101-related compounds: New, subtype-selective alpha(1)-adrenoreceptor antagonists (or inverse agonists?) 202
Design, synthesis and binding affinity of acetylcholine carbamoyl analogues 198
Green Oxidation of Ketones to Lactones with Oxone in Water 196
A Photoactivatable Version of Ivabradine Enables Light-Induced Block of HCN Current In Vivo 192
Simple process for the preparation of cetyltrimethylammonium naproxenate (naprocet) 192
Determinants for α4β2 vs. α3β4 Subtype Selectivity of Pyrrolidine-Based nAChRs Ligands: A Computational Perspective with Focus on Recent cryo-EM Receptor Structures [Determinants for alpha 4 beta 2 vs. alpha 3 beta 4 Subtype Selectivity of Pyrrolidine-Based nAChRs Ligands: A Computational Perspective with Focus on Recent cryo-EM Receptor Structures] 192
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NON-PEPTIDIC INHIBITORS OF FARNEYLTRANSFRERASE 191
A highly efficient method for the alpha,beta-dehydrogenation of alpha-amino esters and alpha-amino-beta-diesters 189
Preparation of enantiopure methionine, arginine, tryptophan, and proline benzyl esters in green ethers by Fischer–Speier reaction 188
Diastereomeric 2-aminomethyl-1,4-benzodioxane mandelates : phase diagrams and resolution 185
Entrainment resolution of carnitinamide chloride 184
Synthesis of α-Hydroxy Fatty Acids from Fatty Acids by Intermediate α-Chlorination with TCCA under Solvent-Free Conditions: A Way to Valorization of Waste Fat Biomasses 184
Analytical, computational and formulation studies on TPGS as P-gp inhibitor 178
A simple route to synthesize (E)-3 propyl-4-oxo-2-butenoic acid esters through the Z isomer 178
From 2-aminomethyl-1,4-benzodioxane enantiomers to unichiral 2-cyano- and 2-carbonyl-substituted benzodioxanes via dichloroamine 175
Subnanomolar Affinity and Selective Antagonism at α7 Nicotinic Receptor by Combined Modifications of 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) 173
Novel inhibitors of the bacterial cell division protein FtsZ: synthesis and antibacterial activity 168
From 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) to Selective Small-Molecule Antagonists of Human α9α10 Nicotinic Receptor by Modifications at the Ammonium Ethyl Residue [From 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) to Selective Small-Molecule Antagonists of Human alpha 9 alpha 10 Nicotinic Receptor by Modifications at the Ammonium Ethyl Residue] 168
Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats 167
Fractioning and Compared 1H NMR and GC-MS Analyses of Lanolin Acid Components 167
Resolution of 2-substituted 1,4-benzodioxanes by entrainment 166
Sustainable Routes for Wool Grease Removal Using Green Solvent Cyclopentyl Methyl Ether in Solvent Extraction and Biosurfactant Wool Protein Hydrolyzate in Scouring 165
Design of a photo-activatable ivabradine to enable light induced block of HCN current in tissues 165
Methyl 8- and 5-Bromo-1,4-Benzodioxane-2-carboxylate: Unambiguous Identification of the Two Regioisomers 163
Enantiomerically Pure Dibenzyl Esters of L‑Aspartic and L‑Glutamic Acid 163
Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S-prolinol as α4β2-nicotinic acetylcholine receptor ligands 163
Design of a H₂O₂-generating P450SPα fusion protein for high yield fatty acid conversion 162
Modelling of full-length human α4β2 nicotinic receptor by fragmental approach and analysis of its binding modes 161
Preparation and unequivocal identification of the regioisomers of nitrocatechol monobenzyl ether 161
The Antioxidant Role of Hemp Phytocomplex in Cannabis Oil-Based Extracts 160
One-pot racemization process of 1-phenyl-1,2,3,4-tetrahydroisoquinoline : a key intermediate for the antimuscarinic agent solifenacin 158
Antihypertensive phytocomplexes of proven efficacy and weel-established use: mode of action and individual characterization of the active constituents 156
Methyl 8- and 5-Nitro-1,4-Benzodioxane-2-Carboxylate 152
Pyrrolidinyl benzofurans and benzodioxanes: Selective α4β2 nicotinic acetylcholine receptor ligands with different activity profiles at the two receptor stoichiometries 149
Highly efficient racemisation of a key intermediate of the antibiotic moxifloxacin 148
Predicting the physicochemical profile of diastereoisomeric histidine-containing dipeptides by property space analysis 146
Crystallization-based resolution of 1,4-benzodioxane-2-carboxylic acid enantiomers via diastereomeric 1-phenylethylamides 146
Enantiomer systems of carnitinamide inorganic salts: introductory studies to a successful entrainment resolution 144
Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency 136
From carnitinamide to 5-aminomethyl-2-oxazolidinones 136
Unlocking the chemistry of PLA-based copolymers: activated benzaldehyde-DOX monomers from biobased α-hydroxy fatty acids as versatile comonomers to highly-loaded functional materials 135
Green Oxidation of Heterocyclic Ketones with Oxone in Water 135
Phase Diagrams to Evaluate the Opportunity for Enantiomeric Enrichment of Some Nonracemic Mixtures of Amino Acid Benzyl Esters by Crystallization as p-Toluenesulfonate Salts 134
Small molecule ligands for α9 * and α7 nicotinic receptors: A survey and an update, respectively 129
Addressing Motor Dysfunction by a Selective α6-Containing Nicotinic Receptor Antagonist 126
ENANTIOPURI, senza usare solventi ‘HH’ 123
3-Ethoxycarbonyl-1,4-benzodioxin-2-carboxylic Acid 122
Totale 22.029
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Categoria #
all - tutte 61.948
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 61.948
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021251 0 0 0 0 0 0 0 0 0 0 178 73
2021/20221.931 127 51 39 74 144 136 503 97 204 134 125 297
2022/20231.986 271 239 198 185 202 303 72 141 185 38 89 63
2023/20241.597 73 106 95 136 291 133 88 166 63 145 132 169
2024/20253.511 126 252 79 343 318 187 184 342 215 388 349 728
2025/20267.166 721 595 789 613 641 429 840 350 723 567 898 0
Totale 23.106