The identification of cannabis chemotypes at an early stage of a plant’s growth, which is long before anthesis, has been intensively pursued in order to control the on-target selection of the cultivar type at the beginning of cultivation, so as to avoid economic and legal drawbacks. However, this issue has been systematically addressed by only few and relatively recent studies of analytical chemistry, possibly because result validations require long-term monitoring of the content and ratio of cannabinoids and terpenes in a great number of plant specimens suitably selected and grown. Here, we review the procedures, the chromatographic techniques and the statistics used in topical investigations during the past thirteen years. Through heterogeneous and not easily comparable approaches, they prove the feasibility of chemotypes safe determination within the first month of a plant’s life.

Development and Early Identification of Cannabis Chemotypes during the Plant Growth: Current Analytical and Chemometric Approaches / C. Bolchi, M. Pallavicini, E. Casagni, E. Vieira de Manincor, V. Gambaro, M. Dei Cas, G. Roda. - In: ANALYTICAL SCIENCES. - ISSN 0910-6340. - 37:12(2021 Dec), pp. 1665-1673. [10.2116/analsci.21R004]

Development and Early Identification of Cannabis Chemotypes during the Plant Growth: Current Analytical and Chemometric Approaches

C. Bolchi
Primo
;
M. Pallavicini
Secondo
;
E. Casagni;V. Gambaro;M. Dei Cas
Penultimo
;
G. Roda
Ultimo
2021

Abstract

The identification of cannabis chemotypes at an early stage of a plant’s growth, which is long before anthesis, has been intensively pursued in order to control the on-target selection of the cultivar type at the beginning of cultivation, so as to avoid economic and legal drawbacks. However, this issue has been systematically addressed by only few and relatively recent studies of analytical chemistry, possibly because result validations require long-term monitoring of the content and ratio of cannabinoids and terpenes in a great number of plant specimens suitably selected and grown. Here, we review the procedures, the chromatographic techniques and the statistics used in topical investigations during the past thirteen years. Through heterogeneous and not easily comparable approaches, they prove the feasibility of chemotypes safe determination within the first month of a plant’s life.
Cannabinoids; terpenes; THC; CBD; cannabis sativa; chemotype; plant growth
Settore CHIM/08 - Chimica Farmaceutica
Settore BIO/15 - Biologia Farmaceutica
dic-2021
lug-2021
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/888490
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