IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca

CLEMENTI, FRANCESCO
 Distribuzione geografica
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Continente #
EU - Europa 7.986
NA - Nord America 6.943
AS - Asia 5.891
Continente sconosciuto - Info sul continente non disponibili 1.171
SA - Sud America 580
AF - Africa 133
OC - Oceania 29
Totale 22.733
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Nazione #
US - Stati Uniti d'America 6.586
GB - Regno Unito 2.179
CN - Cina 1.903
SG - Singapore 1.532
DE - Germania 1.498
IT - Italia 1.386
SE - Svezia 698
RU - Federazione Russa 586
HK - Hong Kong 535
FR - Francia 492
BD - Bangladesh 432
BR - Brasile 399
VN - Vietnam 370
UA - Ucraina 309
IN - India 270
TR - Turchia 265
KR - Corea 235
CA - Canada 193
NL - Olanda 190
IE - Irlanda 181
EU - Europa 160
FI - Finlandia 150
JP - Giappone 82
CO - Colombia 75
HN - Honduras 61
ES - Italia 59
CI - Costa d'Avorio 48
ID - Indonesia 46
MX - Messico 45
PL - Polonia 43
DK - Danimarca 42
AR - Argentina 33
BE - Belgio 32
GR - Grecia 27
AU - Australia 23
EC - Ecuador 23
IQ - Iraq 23
ZA - Sudafrica 22
UZ - Uzbekistan 21
PK - Pakistan 20
SC - Seychelles 18
KZ - Kazakistan 17
PH - Filippine 17
CL - Cile 16
CZ - Repubblica Ceca 16
CH - Svizzera 15
MY - Malesia 14
BZ - Belize 12
PT - Portogallo 12
TW - Taiwan 12
VE - Venezuela 12
AL - Albania 11
JO - Giordania 11
TH - Thailandia 11
IL - Israele 10
IR - Iran 10
RO - Romania 10
SA - Arabia Saudita 10
TN - Tunisia 10
AE - Emirati Arabi Uniti 9
MA - Marocco 8
BO - Bolivia 7
GT - Guatemala 7
AT - Austria 6
CR - Costa Rica 6
KE - Kenya 6
LV - Lettonia 6
TT - Trinidad e Tobago 6
JM - Giamaica 5
KG - Kirghizistan 5
LT - Lituania 5
NO - Norvegia 5
NZ - Nuova Zelanda 5
UY - Uruguay 5
BB - Barbados 4
BG - Bulgaria 4
DO - Repubblica Dominicana 4
LU - Lussemburgo 4
NP - Nepal 4
PE - Perù 4
PY - Paraguay 4
BA - Bosnia-Erzegovina 3
DZ - Algeria 3
EG - Egitto 3
ET - Etiopia 3
MD - Moldavia 3
PR - Porto Rico 3
RS - Serbia 3
SK - Slovacchia (Repubblica Slovacca) 3
SV - El Salvador 3
TZ - Tanzania 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
AO - Angola 2
AZ - Azerbaigian 2
BH - Bahrain 2
BY - Bielorussia 2
CY - Cipro 2
GA - Gabon 2
IS - Islanda 2
Totale 21.685
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Città #
Southend 1.885
Singapore 836
Ashburn 699
Hanover 670
Chandler 572
Hong Kong 486
Milan 396
San Jose 362
Beijing 360
Dallas 292
Seattle 256
Santa Clara 235
Jacksonville 225
Princeton 220
Los Angeles 189
Wilmington 187
Council Bluffs 180
Dublin 179
Ann Arbor 166
Redmond 148
Ho Chi Minh City 129
Mountain View 129
Nanjing 129
New York 129
Buffalo 122
Bengaluru 120
Toronto 116
Dearborn 104
Frankfurt am Main 91
Houston 90
Lauterbourg 86
Sakarya 86
Serra 86
Boardman 84
Guangzhou 84
Hanoi 84
Woodbridge 82
Hefei 81
Somerville 72
Des Moines 70
Moscow 69
The Dalles 69
Andover 67
Fairfield 67
Shanghai 66
Shenyang 65
Bogotá 64
Munich 64
Columbus 61
Jinan 60
Tokyo 59
Centro 51
Rome 50
Abidjan 48
Phoenix 46
Changsha 40
São Paulo 38
Helsinki 37
Nanchang 37
Seoul 36
Tianjin 36
Redwood City 32
Shenzhen 32
Hangzhou 31
Brussels 30
Nürnberg 30
Fuzhou 29
Cangzhou 27
Warsaw 27
Hebei 25
Istanbul 25
Zhengzhou 25
Kunming 24
Chicago 23
Montreal 23
Athens 22
Jiaxing 22
Kiez 22
Berlin 21
Eitensheim 21
Jakarta 21
London 21
Rio de Janeiro 21
Barcelona 20
Cambridge 20
San Diego 20
Atlanta 19
Wuhan 19
Bitonto 18
Medford 18
Mexico City 18
Mumbai 18
Da Nang 17
Florence 17
Naples 17
Auburn Hills 16
Odernheim 16
Quanzhou 16
Seongnam 16
Stockholm 16
Totale 12.502
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Nome #
Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors 817
Synthesis and alpha4beta2 nicotinic affinity of 2-pyrrolidinylmethoxyimines and prolinal oxime ethers 575
Epiboxidine and Novel Related Analogues : a Convenient Synthetic Approach and Estimation of Their Affinity at Neuronal Nicotinic Acetylcholine Receptor Subtypes 534
11,2-bis-N-cytisinylethane (CC4), a new nicotinic partial agonist, blocks nicotine- and Δ-9-tetrahydrocannabinol-induced conditioned place preference in zebrafish 492
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9- nicotinic ligands on glioblastoma cells 450
Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes 392
Farmacologia generale e molecolare 356
Inflammation and neurological adverse drugs reactions : a case of long lasting impaired consciousness after oxatomide administration in a patient with gastroenteritis 352
Persistent cognitive and affective alterations at late withdrawal stages after long-term intermittent exposure to tobacco smoke or electronic cigarette vapour : Behavioural changes and their neurochemical correlates 340
null 326
Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan 313
Increased sensitivity to D9-THC-induced rewarding effects after seven-week exposure to electronic and tobacco cigarettes in mice 313
New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: Synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations 288
Effetto del CC4, un nuovo antagonista del recettore nicotinico, sui processi cognitivi e sul reward da nicotina 278
Synthesis of epibatidine-related Delta(2)-isoxazoline derivatives and evaluation of their binding affinity at neuronal nicotinic acetylcholine receptors 264
alpha9- and alpha7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line 264
Expression of nigrostriatal alpha 6-containing nicotinic acetylcholine receptors is selectively reduced, but not eliminated, by beta 3 subunit gene deletion 263
Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation 262
Transcription factor PHOX2A regulates the human {alpha}3 nicotinic receptor subunit gene promoter 261
Neuronal and extraneuronal expression and regulation of the human alpha5 nicotinic receptor subunit gene 260
Nicotinic receptors increase cell proliferation and tumour progression in non-small cell lung cancer cell line 258
Design, Synthesis, and Pharmacological Characterization of Novel Spirocyclic Quinuclidinyl-Δ2-Isoxazoline Derivatives as Potent and Selective Agonists of α7 Nicotinic Acetylcholine Receptors 257
I recettori e modulazione delle risposte recettoriali 254
Synthesis of novel chiral Δ2-isoxazoline derivatives related to ABT-418 and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes 252
Developmental expression of heteromericnicotinic receptor subtypes in chick retina 251
Anti-neuronal nicotinic receptor antibodies in MG patients with thymoma 248
The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors 245
Cross-regulation of PHOX2A and PHOX2B transcription factors in the development of the Autonomic Nervous System 244
Novel ligands for neuronal nicotinic receptor subtypes: synthetic, pharmacological and molecular docking studies 243
Brain neuronal nicotinic receptors as new targets for drug discovery 240
The enantiomers of epiboxidine and of two related analogs: Synthesis and estimation of their binding affinity at α4β2 and α7 neuronal nicotinic acetylcholine receptors 237
A human neuroblastoma cell line for neurotoxicity testing in vitro: effects of heavy metals 235
The expression of PHOX2A, PHOX2B and of their target gene dopamine-beta-hydroxylase (DbetaH) is not modified by exposure to extremely-low-frequency electromagnetic field (ELF-EMF) in a human neuronal model 230
Synthesis and binding affinity at α4β2 and α7 nicotinic acetylcholine receptors of new analogs of epibatidine and epiboxidine containing the 7-azabicyclo[2.2.1]hept-2-ene ring system 230
Phox2b regulates its own expression by a transcriptional auto-regulatory mechanism 226
Retinoic acid controls PHOX2A expression by means of a dual regulatory mechanism 225
Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors 225
Epiboxidine and Novel-Related Analogues: A Convenient Synthetic Approach and Estimation of Their at Neuronal Nicotinic Acetylcholine Receptor Subtypes 225
Long-term exposure to the new nicotinic antagonist 1,2-bisN-cytisinylethane upregulates nicotinic receptor subtypes of SH-SY5Y human neuroblastoma cells 223
New spirocyclic Δ2-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors 223
SP proteins and PHOX2B regulate the expression of the human PHOX2A gene 220
Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization 220
Transcriptional regulation of the human alpha5 nicotinic receptor subunit gene in neuronal and non-neuronal tissues 218
Nicotinic acetylcholine receptor subtypes expression during rat retina development and their regulation by visual experience 217
Synthesis and alpha 4 beta 2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes 215
Cross-regulation of PHOX2A and PHOX2B transcription factors in the development of the Autonomic Nervous System 214
Extremely low-frequency electromagnetic field (ELF-EMF) does not affect the expression of a3, a5 and a7 nicotinic receptor subunit genes in SH-SY5Y neuroblastoma cell line 213
Phox2a regulates the expression of the human alpha3 nAChR gene by two mechanisms : DNA-dependent and DNA independent 208
CC4, a dimer of cytisine, is a selective partial agonist at α4β2 / α6β2 nAChR with improved selectivity for tobacco smoking cessation 205
The enantiomers of epiboxidine: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes 204
Nicotine-Modulated Subunit Stoichiometry Affects Stability and Trafficking of α3β4 Nicotinic Receptor 202
Brain nicotinic acetylcholine receptors : native subtypes and their relevance 199
Trasmissione Serotoninergica 198
Novel spirocyclic delta2-isoxazoline derivatives as lower homologues of selective agonists for neuronal alpha-7 nicotinic acetylcholine receptor subtypes 197
N-(Arylalkyl)- and N-(Aroylalkyl)-Cytisines as ligands for neuronal nicotinic acetylcholine receptor subtypes 193
Subnanomolar Affinity and Selective Antagonism at α7 Nicotinic Receptor by Combined Modifications of 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) 192
Heterogeneity and complexity of native brain nicotinic receptors 190
Neuronal nicotinic receptors : from structure to pathology 189
A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic receptor subtypes 187
Cholinergic nicotinic receptor involvement in movement disorders associated with Lewy body diseases. An autoradiography study using [I-125]alpha-conotoxinMII in the striatum and thalamus 186
Synthesis, binding, and modeling studies of new cytisine derivatives, as ligands for neuronal nicotinic acetylcholine receptor subtypes 185
Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice 183
Subunit composition of nicotinic receptors in monkey striatum : effect of treatments with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine or L-DOPA 182
Partial deletion of the nicotinic cholinergic receptor alpha 4 or beta 2 subunit genes changes the acetylcholine sensitivity of receptor-mediated 86Rb+ efflux in cortex and thalamus and alters relative expression of alpha 4 and beta 2 subunits 182
Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS 179
Human neuronal nicotinic receptors 179
Metabolism and trafficking of N-type voltage-operated calcium channels in neurosecretory cells 178
Nicotinic agonists selective for the Alpha7 Receptor Subtype, the process for their preparation thereof and pharmaceutical compositions therefrom 175
Novel bicylic delta2-isoxazoline and 3-oxo-isoxazolidine derivatives : synthesis and binding affinity at neuronal nicotinic receptor subtypes 173
Chromosomal localization and physical linkage of the genes encoding the human alpha 3, alpha 5, and beta 4 neuronal nicotinic receptor subunits 167
Role of lipid microdomains in P/Q-type calcium channel (Cav2.1) clustering and function in presynaptic membranes 166
Regulation of neuronal nicotinic receptor traffic and expression 164
The expression of the human neuronal alpha3 Na+,K+-ATPase subunit gene is regulated by the activity of the Sp1 and NF-Y transcription factors 162
Nitrogen substitution modifies the activity of cytisine on neuronal nicotinic receptor subtypes. 160
Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: localization of alpha 3 subunit mRNA, alpha-bungarotoxin and nicotine binding sites 160
New Hybrid and Mutant PIA and MII Toxins with Greater Affinty and Selectivity for the A6* Subtype 159
4-oxystilbene compounds are selective ligands for neuronal nicotinic alpha Bungarotoxin receptors 159
Acetylcholine operated ion channel and alpha-bungarotoxin binding site in a human neuroblastoma cell line reside on different molecules 158
Molecular cloning of human neuronal nicotinic receptor alpha 3-subunit 157
The minimal promoter of the human alpha3 nicotinic receptor subunit gene : molecular and functional characterization 155
Alpha7 and alpha8 nicotinic receptor subtypes immunopurified from chick retina have different immunological, pharmacological and functional properties 155
A selective antagonist for the neuronal alpha7 nAChR subtype 155
Expression and transcriptional regulation of the human alpha3 neuronal nicotinic receptor subunit in T lymphocyte cell lines 155
Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: Identification of a new native nAChR subtype alpha 3 beta 2(alpha 5 or beta 3) enriched in retinocollicular afferents 153
I recettori canale 152
Neuronal nicotinic receptors, important new players in brain function 152
Calcium channel autoantibody and non-small-cell lung cancer in patients with Lambert-Eaton syndrome 151
George Palade and cell biology in Milan 149
Expression of the alpha3 nicotinic receptor subunit mRNA in aging and Alzheimer's disease 146
Docking studies and crystal structure determination of new cytisine derivatives 137
The binding site for alpha-bungarotoxin resides in the sequence 188-201 of the alpha-subunit of acetylcholine receptor: structure, conformation and binding characteristics of peptide [Lys] 188-201 136
The nicotinic receptors in the nervous system 136
Localization of synaptic proteins involved in neurosecretion in different membrane microdomains 133
Structural and Docking studies of new cytisine derivatives 133
Neuronal nicotinic acetylcholine receptors: from structure to therapeutics 130
Expression of neuronal acetylcholine nicotinic receptor alpha 4 and beta 2 subunits during postnatal development of the rat brain 130
Glutamatergic reinnervation and assembly of glutamatergic synapses in adult rat skeletal muscle occurs at cholinergic endplates 128
Farmacoutilizzazione e farmacovigilanza nell'anziano : analisi delle segnalazioni spontanee di sospette reazioni avverse in italia nel 2007 127
Nicotinic acetylcholine receptors in the mesolimbic pathway: primary role of ventral tegmental area alpha6beta2* receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement 120
Reduced platelet aggregability and increased vascular prostacyclin formation in a variant rat strain (IVA-SIV) with endogenous hypertriglyceridemia 118
Totale 22.417
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Categoria #
all - tutte 54.181
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 54.181
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.828 0 34 46 85 144 146 442 126 225 155 141 284
2022/20231.780 229 198 157 208 188 315 51 145 162 20 56 51
2023/20241.062 39 88 70 71 288 78 36 70 16 57 116 133
2024/20252.639 89 212 51 321 205 160 109 285 126 207 309 565
2025/20265.803 554 355 703 395 502 423 767 254 511 399 488 452
2026/2027666 401 265 0 0 0 0 0 0 0 0 0 0
Totale 22.733