IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca

TEDESCO, BARBARA
 Distribuzione geografica
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Continente #
AS - Asia 8.074
EU - Europa 7.881
NA - Nord America 7.030
SA - Sud America 601
AF - Africa 197
OC - Oceania 100
Continente sconosciuto - Info sul continente non disponibili 1
Totale 23.884
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Nazione #
US - Stati Uniti d'America 6.760
DE - Germania 2.599
CN - Cina 2.462
SG - Singapore 2.180
IT - Italia 2.009
GB - Regno Unito 1.005
HK - Hong Kong 733
VN - Vietnam 659
BD - Bangladesh 516
BR - Brasile 465
RU - Federazione Russa 431
IN - India 385
SE - Svezia 354
FR - Francia 335
JP - Giappone 318
NL - Olanda 262
KR - Corea 253
CA - Canada 173
DK - Danimarca 154
IE - Irlanda 144
ID - Indonesia 141
FI - Finlandia 125
CI - Costa d'Avorio 99
TR - Turchia 99
AU - Australia 95
BE - Belgio 87
TW - Taiwan 82
ES - Italia 63
PL - Polonia 62
MX - Messico 57
AT - Austria 47
AR - Argentina 40
CH - Svizzera 39
UA - Ucraina 36
ZA - Sudafrica 31
IQ - Iraq 28
EC - Ecuador 26
IL - Israele 26
PH - Filippine 24
CO - Colombia 22
PK - Pakistan 21
CL - Cile 19
IR - Iran 18
GR - Grecia 17
MY - Malesia 16
EG - Egitto 14
SA - Arabia Saudita 14
SI - Slovenia 14
HU - Ungheria 13
UZ - Uzbekistan 12
KE - Kenya 11
MA - Marocco 11
NP - Nepal 11
RO - Romania 11
MO - Macao, regione amministrativa speciale della Cina 10
CZ - Repubblica Ceca 9
AE - Emirati Arabi Uniti 8
LT - Lituania 8
LU - Lussemburgo 8
PT - Portogallo 8
VE - Venezuela 8
CR - Costa Rica 7
PE - Perù 7
TH - Thailandia 7
TN - Tunisia 7
NO - Norvegia 6
PY - Paraguay 6
SC - Seychelles 6
DZ - Algeria 5
JM - Giamaica 5
JO - Giordania 5
KZ - Kazakistan 5
NZ - Nuova Zelanda 5
OM - Oman 5
RS - Serbia 5
AD - Andorra 4
AL - Albania 4
AZ - Azerbaigian 4
BO - Bolivia 4
GE - Georgia 4
GT - Guatemala 4
LB - Libano 4
PA - Panama 4
SK - Slovacchia (Repubblica Slovacca) 4
TT - Trinidad e Tobago 4
BA - Bosnia-Erzegovina 3
CY - Cipro 3
EE - Estonia 3
ET - Etiopia 3
HR - Croazia 3
KG - Kirghizistan 3
LV - Lettonia 3
MM - Myanmar 3
MT - Malta 3
NI - Nicaragua 3
PR - Porto Rico 3
UY - Uruguay 3
AM - Armenia 2
BB - Barbados 2
BH - Bahrain 2
Totale 23.850
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Città #
Hanover 1.663
Singapore 1.284
Ashburn 911
Milan 667
Southend 620
Hong Kong 581
San Jose 492
Frankfurt am Main 461
Beijing 367
Council Bluffs 327
Chandler 318
Dallas 297
Hefei 251
New York 240
Santa Clara 228
Los Angeles 212
Fairfield 199
Ho Chi Minh City 199
Hanoi 155
Boardman 153
Seoul 139
Dublin 138
Bengaluru 124
Ann Arbor 123
Jakarta 122
Princeton 122
Shanghai 114
Munich 113
Cambridge 111
Wilmington 109
Lauterbourg 107
Guangzhou 103
Abidjan 99
Seattle 99
Phoenix 97
Tokyo 95
Chicago 90
Rome 82
Moscow 81
Houston 79
Buffalo 74
Woodbridge 74
Helsinki 73
Dearborn 71
Redwood City 71
The Dalles 64
Istanbul 63
Philadelphia 63
Nanjing 58
Nuremberg 52
Grafing 51
Cangzhou 50
Atlanta 48
Medford 48
Da Nang 47
Boston 46
Des Moines 46
Magenta 45
Naples 45
São Paulo 44
Turin 44
Zhengzhou 41
Irvine 39
Montreal 38
Amsterdam 37
Taichung 37
Delhi 36
Shenyang 36
Wuhan 35
Basingstoke 34
Jinan 34
Toronto 34
Mumbai 33
Tianjin 33
Warsaw 33
Fuzhou 31
Genoa 30
London 30
San Francisco 30
Indianapolis 29
Columbus 26
Dong Ket 26
Haiphong 26
Vienna 26
Brooklyn 25
Chennai 25
Honolulu 25
Lappeenranta 25
Brussels 24
Fremont 24
Paris 24
Quanzhou 24
Turku 24
Changsha 23
Nanchang 23
Berlin 22
Florence 22
Melbourne 22
Shenzhen 22
Sydney 22
Totale 14.079
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Nome #
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration 1.215
The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases 558
Autophagic and Proteasomal Mediated Removal of Mutant Androgen Receptor in Muscle Models of Spinal and Bulbar Muscular Atrophy 555
Transforming Growth Factor beta 1 signaling is altered in the spinal cord and muscle of amyotrophic lateral sclerosis mice and patients 540
Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells 524
Retinoic Acid Downregulates HSPB8 Gene Expression in Human Breast Cancer Cells MCF-7 474
BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes 447
GAIN OF TOXIC FUNCTION OF CHAPERONE ASSISTED SELECTIVE AUTOPHAGY MEMBERS IN NEUROMUSCULAR DISEASES: A CHARACTERIZATION OF DISEASE-RELATED MUTANTS 387
The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases 303
Analysis of the autophagic response in models of KIF5A-related neurodegeneration 298
The chaperone-assisted selective autophagy complex dynamics and dysfunctions 295
Molecules capable to induce neuroprotection via lysophagy activation 294
Enhanced Clearance of Neurotoxic Misfolded Proteins by the Natural Compound Berberine and Its Derivatives 285
Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice 276
The role of Extracellular Vesicles (EVs) in Amyotrophic Lateral Sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) 273
The regulation of the small heat shock protein B8 in misfolding protein diseases causing motoneuronal and muscle cell death 267
HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies 260
Chaperone Assisted Selective Autophagy (CASA) a potential target for therapeutics in motoneuron diseases 257
Molecular mechanisms in KIF5A-related neurodegeneration 251
A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases 249
Small heat shock protein B8: from cell functions to its involvement in diseases and potential therapeutic applications 242
Alternative Translation Initiation as a novel strategy to block toxicity of the mutant Androgen Receptor in SBMA 239
The Role of HSPB8, a Component of the Chaperone-Assisted Selective Autophagy Machinery, in Cancer 239
TDP-43 PROTEINOPATHIES: THE ROLE OF EXTRACELLULAR VESICLES 237
Motor neuron degeneration in spinal and bulbar muscular atrophy: molecular approaches to counteract mutant androgen receptor neurotoxicity 237
Multiple Roles of Transforming Growth Factor Beta in Amyotrophic Lateral Sclerosis 234
BAG1 assists the degradation of neurotoxic proteins related to motor neuron diseases counteracting dynein-mediated autophagy alteration 234
TDP25 aggregation in motor neuron and muscle cells is rescued by chaperone overexpression 231
RAN translated C9ORF72 arginine rich poly-dipeptides alter gene transcription in ALS/FTD cell model 231
Generation of novel induced pluripotent stem cell models for the study of spinocerebellar ataxia type 17 230
Identification of new HSPB8 variants linked to familial Amiotrophic Lateral Sclerosis 228
STIP1 Homology And U-Box Containing Protein 1 (STUB1/CHIP) mutants as a key factor on TATA-box binding protein (TBP) behaviour in digenic spinocerebellar ataxia type 17 (SCA17-DI) 224
Pathogenic variants of Valosin Containing Protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells 222
Extracellular vesicles and the secretion of TDP species in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD) 217
VCP mutants cause lysosomal alterations and autophagy induction in ALS-neuronal model 213
Valosin Containing Protein (VCP): A Multistep Regulator of Autophagy 213
ALS-associeted VCP-mutants lead to lysosome damage 211
The clearance of aggregated TDP-43 responsible for ALS/FTD diseases 210
Bicalutamide and Trehalose as a therapeutic approach for SBMA 206
Chaperone mediated autophagy respond to dynein mediated transport inhibition in motor neuron diseases 205
Insights on human small heat shock proteins and their alterations in diseases 203
Effect of Hspb8 deletion in the skeletal muscle of a mouse model for Amyotrophic Lateral Sclerosis 202
Neurodegenerative Disease-Associated TDP-43 Fragments Are Extracellularly Secreted with CASA Complex Proteins 202
How PQC inhibition modulates miRNA loading in large and small extracellular vesicles 200
Altered molecular and cellular mechanisms in KIF5A-associated neurodegenerative or neurodevelopmental disorders 200
The BAG1 molecular chaperone regulators prevent ALS related neurotoxic misfolded proteins accumulation via proteasome and chaperone mediated autophagy 199
STUB1 mutants effect on TBP behavior in digenic spinocerebellar ataxia type 17 197
Chaperone mediated autophagy responds to macroautophagy inhibition in motor neuron diseases 195
VCP modulation rescues C9ORF72 pathological features in ALS-neuronal models 193
VCP ALS-mutants induce lysosomal damage and autophagy activation 192
Novel pathogenic mechanism of ALS-associated VCP- mutants 189
Mechanism of paroxetine-mediated autophagic induction in cell models of ALS/FTD 188
Extracellular vesicles cooperate with PQC system for the clearance of TDP-43 species associated with ALS and FTD 186
Clearance of misfolded proteins in motoneuron disease: the case of Spinal and Bulbar Muscular Atrophy 186
C9ORF72 arginine rich poly-dipeptides induce transcriptional alterations in ALS/FTD cell model 184
Differentiation of isogenic iPSC reporter lines to motoneurons as tools for familial and sporadic amyotrophic lateral sclerosis 182
The role of autophagy-lysosomal pathway in motor neuron diseases 180
Mutations in VCP induce lysosomal alterations and autophagy activation in ALS neuronal models 179
Alternative translation initiatin as a novel strategy to block toxicity of the mutant androgen receptor in SBMA 178
Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases 177
Chaperone-assisted selective autophagy in Health and Disease 175
VCP: a novel regulator of SOD1-G93A clearance in a als model 175
The nucleotide exchange factor BAG1 prevents neurotoxic misfolded proteins accumulation via proteasome and chaperone mediated autophagy 174
Investigating the molecular mechanisms involved in KIF5A-related neurodegeneration 172
Shared behaviours of KIF5A frameshift mutants in neurodevelopment and neurodegeneration 171
VCP mutants induce lysosomal damage and autophagy activation in amyotrophic lateral sclerosis (ALS) 171
The role of Valosin Containing Protein (VCP) in the degradation of neurotoxic protein aggregates in Amyotrophic Lateral Sclerosis 170
Targeting androgen receptor stability and degradation: approaches for developing a therapy for spinal and bulbar muscular atrophy 169
One gene, many phenotypes: investigating KIF5A-linked neurodegeneration mechanisms 168
Insights into KIF5A-related pathways to neurodegeneration 168
Characterization of two new mutations in the small Heat Shock protein B8 HSPB8 and impact in Amyotrophic Lateral Sclerosis cell models 167
Novel role of VCP in the clearance of mutant-SOD1 in als 165
The small heat shock protein B8 at the interplay between the intracellular degradative pathways in motoneuron disease 165
Mutant Androgen Receptor Alternative Translation Initiation as novel strategy to block toxicity in SBMA. 163
The role of extracellular vesicles in the removal of aggregated TDP43 responsible for ALS/FTD diseases 160
Lysosome quality control in health and neurodegenerative diseases 157
Autophagy mediated HSPB8 removal of aggregating dipeptides produced in C9ORF72 related neurodegenerative diseases 155
VCP autophagic modulation rescues C9ORF72 pathological features in ALS-neuronal models 153
HSPB8 counteracts tumor activity of BRAF- and NRAS-mutant melanoma cells by modulation of RAS-prenylation and autophagy 152
Proteotoxic responses in amyotrophic lateral sclerosis 151
Molecular defects in KIF5A-linked neurodegenerative and neurodevelopmental diseases 150
The chaperone HSPB8 removes insoluble forms of the C9ORF72 RAN translated dipeptides responsible for ALS/FTD 148
The small heat shock protein B8 (HSPB8) removes dipeptides produced in C9ORF72-related neurodegenerative diseases 148
The role of extracellular vesicles in the removal of aggregated TDP-43 responsible for ALS/FTD diseases 148
The Role of Small Heat Shock Proteins in Protein Misfolding Associated Motoneuron Diseases 147
Extracellular vesicles and their role in TDP-43 proteinopathies 147
Insights into the neurodegenerative mechanisms associated with KIF5A mutations 146
Transcriptional alterations induced by polyDPRs overexpression in neuronal cell model 145
Analysis of the pathogenetic mechanisms involved in KIF5A-related neurodegenerative disorders 145
Large and small extracellular vesicles may contribute to the propagation of ALS and FTD carrying toxic TDP species and potentially harmful miRNAs 144
Frameshift mutations in the Heat Shock Protein B8 share common pathogenic mechanisms and impair proteostasis 142
Innovative high throughput screening identifies HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases 141
Bcl2-Associated Athanogene 3 mutants : solubility and aggregation prone behaviour assessment by different techniques 139
INSIGHTS INTO MITOCHONDRIAL DYSFUNCTION IN SPINAL AND BULBAR MUSCULAR ATROPHY THROUGH IPSC-DERIVED SKELETAL MUSCLE MODELS 139
Unveiling novel players in HSPB8 pathology caused by frameshift mutations 138
New HSPB8 mutations related to Amyotrophic Lateral Sclerosis : characterization and impact in cell models of disease 138
The role of protein quality control system in Amyotrophic Lateral Sclerosis 137
The role of extracellular vesicles in TDP-43 proteinopathies 133
Shared mechanisms of pathogenicity of frameshift mutations in the heat shock protein B8 associated with neuromyopathies 130
One gene, many phenotypes: altered molecular and cellular mechanisms in KIF5A-associated neurodegenerative and neurodevelopmental disorders 130
Totale 22.459
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Categoria #
all - tutte 68.829
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 68.829
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021229 0 0 0 0 0 0 0 0 0 0 0 229
2021/20222.971 82 131 158 279 267 309 306 255 316 317 265 286
2022/20231.859 131 205 137 115 130 266 100 176 243 63 175 118
2023/20242.562 91 168 266 404 485 89 146 148 96 182 259 228
2024/20254.270 158 296 162 463 415 213 190 426 207 452 417 871
2025/20269.906 889 729 857 777 993 542 1.277 443 944 764 1.376 315
Totale 24.609