PARAPINI, SILVIA
 Distribuzione geografica
Continente #
EU - Europa 11.186
NA - Nord America 11.105
AS - Asia 10.105
SA - Sud America 922
AF - Africa 419
OC - Oceania 53
Continente sconosciuto - Info sul continente non disponibili 6
Totale 33.796
Nazione #
US - Stati Uniti d'America 10.774
CN - Cina 3.108
GB - Regno Unito 3.074
SG - Singapore 2.874
IT - Italia 2.778
DE - Germania 1.311
RU - Federazione Russa 863
SE - Svezia 862
HK - Hong Kong 838
VN - Vietnam 811
BR - Brasile 682
IN - India 581
FR - Francia 560
BD - Bangladesh 554
TR - Turchia 330
NL - Olanda 329
UA - Ucraina 303
IE - Irlanda 276
KR - Corea 267
FI - Finlandia 225
ID - Indonesia 220
CA - Canada 211
DK - Danimarca 172
JP - Giappone 137
CI - Costa d'Avorio 101
CO - Colombia 85
EU - Europa 85
BE - Belgio 65
PL - Polonia 64
AR - Argentina 61
ZA - Sudafrica 56
ES - Italia 54
MX - Messico 50
BF - Burkina Faso 47
IQ - Iraq 44
AU - Australia 40
PH - Filippine 39
TH - Thailandia 36
AT - Austria 35
CH - Svizzera 34
PK - Pakistan 31
GR - Grecia 30
PT - Portogallo 30
MA - Marocco 28
KE - Kenya 27
NG - Nigeria 26
SA - Arabia Saudita 26
UZ - Uzbekistan 26
CL - Cile 25
MY - Malesia 23
RO - Romania 23
EC - Ecuador 22
IR - Iran 21
CZ - Repubblica Ceca 19
PE - Perù 19
EG - Egitto 18
NP - Nepal 16
VE - Venezuela 15
DZ - Algeria 13
NZ - Nuova Zelanda 13
TW - Taiwan 13
CR - Costa Rica 12
HR - Croazia 12
IL - Israele 12
JO - Giordania 12
LT - Lituania 12
AE - Emirati Arabi Uniti 11
TN - Tunisia 11
GH - Ghana 10
HU - Ungheria 10
JM - Giamaica 10
SC - Seychelles 10
LB - Libano 9
NE - Niger 9
NO - Norvegia 9
AZ - Azerbaigian 8
ET - Etiopia 8
GE - Georgia 8
LV - Lettonia 8
TZ - Tanzania 8
UG - Uganda 8
ML - Mali 7
PA - Panama 7
SD - Sudan 7
BG - Bulgaria 6
HN - Honduras 6
KW - Kuwait 6
LU - Lussemburgo 6
PS - Palestinian Territory 6
SV - El Salvador 6
KH - Cambogia 5
KZ - Kazakistan 5
OM - Oman 5
PY - Paraguay 5
AL - Albania 4
BH - Bahrain 4
CM - Camerun 4
CU - Cuba 4
DO - Repubblica Dominicana 4
NI - Nicaragua 4
Totale 33.798
Città #
Southend 2.652
Singapore 1.655
Ashburn 1.167
Milan 1.072
Hong Kong 773
Chandler 740
Ann Arbor 647
Dallas 622
Beijing 596
San Jose 573
Seattle 455
Council Bluffs 425
Frankfurt am Main 419
Fairfield 354
Santa Clara 354
Princeton 344
Wilmington 336
Los Angeles 286
Dublin 268
Dearborn 239
Hanoi 221
Ho Chi Minh City 220
Woodbridge 210
Jacksonville 206
New York 194
Bengaluru 178
Hefei 173
Grafing 170
Houston 170
Lauterbourg 169
Boardman 159
Nanjing 157
Mountain View 151
Jakarta 142
Redmond 138
Guangzhou 137
Rome 134
Des Moines 127
Cambridge 123
Buffalo 120
Moscow 115
Toronto 115
Shanghai 110
Redwood City 109
Phoenix 106
Istanbul 103
Jinan 101
Munich 101
Abidjan 99
Tokyo 87
Monza 86
Shenyang 84
Sakarya 78
Pisa 75
Serra 72
Seoul 71
Helsinki 70
Bogotá 68
Berlin 65
Cangzhou 63
Andover 62
The Dalles 58
Tianjin 56
Columbus 55
Hangzhou 54
Changsha 51
São Paulo 51
Medford 48
Zhengzhou 48
Brussels 47
Somerville 47
Hebei 45
Nanchang 45
Chicago 43
Falls Church 43
Da Nang 41
Jiaxing 41
Naples 41
San Diego 40
London 39
Nuremberg 39
Warsaw 39
Ouagadougou 36
Ningbo 35
Washington 34
Mumbai 32
Torino 31
Fuzhou 30
Atlanta 29
Taizhou 29
Haikou 28
Bitonto 26
Bologna 26
Orem 26
Shenzhen 25
Athens 24
Haiphong 24
Kent 24
Roxbury 24
Turin 24
Totale 20.594
Nome #
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine : identification of a suitable "back-up" compound for N-tert-butyl isoquine 388
The Fe(2+)-Mediated Decomposition, PfATP6 Binding, and Antimalarial Activities of Artemisone and Other Artemisinins : The Unlikelihood of C-Centered Radicals as Bioactive Intermediates 355
High antiplasmodial activity of novel plasmepsins I and II inhibitors 331
Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents 329
Attività antimalarica e antileishmaniosi degli oli essenziali di myrtus communis L. e eugenia uniflora L. 329
In vitro studies on the mechanism of action of two compounds with antiplasmodial activity : ellagic acid and 3,4,5-trimethoxyphenyl(6′-O-Galloyl)-β-D-glucopyranoside 329
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents 320
Accelerated senescence of human erythrocytes cultured with Plasmodium falciparum 319
In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline : A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial 316
ANTI-PLASMODIAL AND IMMUNOMODULATORY ACTIVITY OF MEDICINAL PLANTS USED IN BURKINA FASO AGAINST MALARIA 312
Anti-plasmodial activity of Ailanthus excelsa 309
Salinomycin and other ionophores as a new class of antimalarial drugs with transmission-blocking activity 309
Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities and consideration of their mode of action 306
Interplay between Plasmodium falciparum haemozoin and L-arginine : implication for nitric oxide production 304
Old and new targets for innovative antimalarial compounds : the different strategies of the Italian Malaria Network 302
Binding of endothelin-1 to the lipid moiety of haemozoin and P. falciparum parasitised red blood cells 294
The lipid moiety of haemozoin (Malaria Pigment) and P. falciparum parasitised red blood cells bind synthetic and native endothelin-1 293
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond 293
Benzimidazole derivatives endowed with potent antileishmanial activity 291
Phagocytosis and activation of bone marrow-derived macrophages by Plasmodium falciparum gametocytes 291
Design, Synthesis and In Vitro Investigation of Novel Basic Celastrol Carboxamides as Bio-Inspired Leishmanicidal Agents Endowed with Inhibitory Activity against Leishmania Hsp90 287
Activity of human erythrocyte membrane-bound glycohydrolases is related to Plasmodium Falciparum products 283
Falciparum malaria and severe anaemia : how the parasite and its metabolic products modify red blood cell membranes 275
Progress towards malaria eradication : new screening assays and new compounds with anti-gametocyte activity 275
Discovery and pharmacophore mapping of a new low nanomolar inhibitor of P. falciparum growth 271
4-Aminoquinoline-statine double drugs 270
Endoperoxide derivatives from marine organisms: 1,2-dioxanes of the plakortin family as novel antimalarial agents 267
In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release 262
4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity 259
Anti-plasmodial and immunomodulatory activity of medicinal plants used in Burkina Faso to treat malaria 256
Discovery of oxybisbenzoylamides as a new class of antimalarial agents 256
Design and development of plastic antibodies against SARS-CoV-2 RBD based on molecularly imprinted polymers that inhibit in vitro virus infection 255
THERAPEUTIC VALUE OF MEDICINAL PLANTS USED IN BURKINA FASO TO TREAT MALARIA: IDENTIFICATION OF ANTI-PLASMODIAL AND ANTIPYRETIC ACTIVITY IN EXTRACTS OF CANTHIUM HENRIQUESIANUM (K. SCHUM), GARDENIA SOKOTENSIS (HUTCH) AND VERNONIA COLORATA (WILLD) 253
Facile Preparation of N-Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities 249
Malaria pigment accelerates MTT - Formazan exocytosis in human endothelial cells 249
Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro 245
PLASMEPSIN II INHIBITION AND ANTIPLASMODIAL ACTIVITY OF PRIMAQUINE-STATINE “DOUBLE-DRUGS” 242
Antiplasmodial activities of 4-aminoquinoline–statine compounds 241
In vitro characterization, structural optimization and in silico pharmacophore modeling of a new antiplasmodial chemotype 239
A rapid spectrophotometric method to identify inhibitors of human erythropoiesis 239
Innate immune response against Plasmodium falciparum gametocytes: phagocytosis and activation of bone marrow derived macrophages 237
A chemical susceptibility profile of the Plasmodium falciparum transmission stages by complementary cell-based gametocyte assays 236
Heat-Treated Lysozyme Hydrochloride: A Study on Its Structural Modifications and Anti-SARS-CoV-2 Activity 235
Antiparasitic activities and toxicities of individual enantiomers of 7-chloro-N-[[(9a)-octahydro-2H-quinolizin-1-yl]methyl]-4-quinolinamine 233
Longitudinal, virological, and serological assessment of hospitalized COVID-19 patients 232
In vivo evaluation of quinolizidinyl-and quinolizidinylalkyl-derivatives of 4-aminoquinoline using the murine malaria model Plasmodium berghei/anopheles stephensi 231
4-Alkyl- and 4-phenylcoumarins from Mesua ferrea as promising multidrug resistant antibacterials 230
Haem disposal in Plasmodium falciparum: new paradigms for drug targeting and mechanism of action 230
Malaria and leishmaniasis co-infection : the cardinal role of macrophages 228
Role of Stereochemistry on the Biological Activity of Nature-Inspired 3-Br-Acivicin Isomers and Derivatives 227
Human erythrocyte membrane–bound glycohydrolases activity is a ected by Plasmodium falciparum products 226
Antiplasmodial and anti-inflammatory activities of Canthium henriquesianum (K. Schum), a plant used in traditional medicine in Burkina Faso 223
Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds 223
In Vitro Antimalarial Activity of Inhibitors of the Human GTPase Rac1 222
Anti-inflammatory and vasoactive properties of quinoline and artemisinins antimalarials : Modulation of endothelin-1 and cytokines production by microvascular endothelial cells 221
Synthesis and antiplasmodial evaluation of new N-(imidazol-2-yl)-methyl-4-aminoquinolines 217
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 215
In vitro multistage malaria transmission blocking activity of selected malaria box compounds 214
Azacarbazole n-3 and n-6 polyunsaturated fatty acids ethyl esters nanoemulsion with enhanced efficacy against Plasmodium falciparum 212
Quinolizidine-derived lucanthone and amitriptyline analogues endowed with potent antileishmanial activity 212
Antiparasitic Drugs against SARS-CoV-2: A Comprehensive Literature Survey 211
Screening of Mpro Protease (SARS-CoV-2) Covalent Inhibitors from an Anthocyanin-Rich Blueberry Extract Using an HRMS-Based Analytical Platform 211
Synthesis and antiplasmodial activity of new heteroaryl derivatives of 7-chloro-4-aminoquinoline 210
Novel inhibitors of Plasmepsins, a family of haemoglobin proteases of P. Falciparum 209
Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity 209
Clofazimine analogs as antimalarial drugs 208
Dihydroartemisinin inhibits the human erythroid cell differentiation by altering the cell cycle 208
Synthesis and antiplasmodial activity of new heteroaryl derivatives of 7-chloro-4-aminoquinoline 207
Listening to nature's hints : exploiting a natural product scaffold to simplify a complex chemical structure 207
Favorable Preclinical Pharmacological Profile of a Novel Antimalarial Pyrrolizidinylmethyl Derivative of 4-amino-7-chloroquinoline with Potent In Vitro and In Vivo Activities 205
Two-Step Flow Amidation of Natural Phenolic Acids as Antiradical and Antimicrobial Agents 204
Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinolines 204
Safety of artemisinin derivatives in the first trimester of pregnancy : a controversial story 204
In vitro and in vivo evaluation and early transitioning studies of novel quinolizidinyl- and quinolizidinylalkyl- derivatives of 4-aminoquinoline with potent antimalarial activity 203
Target-Oriented Development Of Novel Antiprotozoal Agents: Celastrol Carboxamides As Inhibitors Of Leishmania Hsp90 202
A chemical proteomic approach in antimalarial drugs discovery 201
Novel Hydrophilic Riminophenazines as Potent Antiprotozoal Agents 201
From DC18 to MR07: A Metabolically Stable 4,4′‐Oxybisbenzoyl Amide as a Low‐Nanomolar Growth Inhibitor of P. falciparum 200
Plasmepsin II inhibition and antiplasmodial activity of Primaquine-Statine 'double-drugs' 200
Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline 195
Chemical proteomics approach for target identification of a new antimalarials 195
Structural optimization, in vitro characterization and in silico pharmacophore modeling of a new antiplasmodial chemotype 195
Leishmania Promastigotes Enhance Neutrophil Recruitment through the Production of CXCL8 by Endothelial Cells 194
Damicoside from Axinella damicornis : the influence of a glycosylated galactose 4-OH group on the immunostimulatory activity of a-galactoglycosphingolipids 193
New hydrophilic riminophenazines as potent antiprotozoal agents 190
Atovaquone-statine "Double-Drugs" with high antiplasmodial activity 189
Design, synthesis and biological characterization of PfGAPDH inhibitors 188
Multiplex array analysis of circulating cytokines and chemokines in COVID-19 patients during the first wave of the SARS-CoV-2 pandemic in Milan, Italy 187
Ability of quinolizidinyl- and quinolizidinylalkyl-derivatives of 4-aminoquinoline to overcome chloroquine resistance 187
Synthesis and comparison of antiplasmodial activity of (+), (-) and racemic 7-chloro-4-(N-lupinyl)aminoquinoline 187
Clofazimine analogs with antileishmanial and antiplasmodial activity 186
In Vitro Antiparasitic Activities of Monovalent Ionophore Compounds for Human and Canine Leishmaniases 185
4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity 182
A chemical proteomic approach in antimarial drugs discovery 181
Effects of antimalarial drugs on the vasoactive and inflammatory properties of human endothelial cells : modulation of endothelin-1 production 180
Role of native Plasmodium falciparum hemozoin in innate immunity 180
Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin 180
In vitro activity of Vancomycin-loaded nanodroplets against Enterococcus spp 180
Antiprotozoal activity of novel diaryliminophenazines 179
Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents : design, synthesis, and biological and structure-activity relationship studies 178
Totale 23.812
Categoria #
all - tutte 106.090
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 106.090


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021189 0 0 0 0 0 0 0 0 0 0 0 189
2021/20222.908 347 217 89 195 252 172 266 155 281 212 214 508
2022/20232.910 385 262 216 284 335 510 95 201 325 54 161 82
2023/20242.103 73 124 153 208 527 129 72 137 47 124 211 298
2024/20254.861 209 455 146 412 437 220 202 510 258 427 467 1.118
2025/202610.917 1.005 716 1.227 847 1.039 683 1.391 511 1.095 780 1.105 518
Totale 35.359