PASINI, DIEGO
PASINI, DIEGO
Dipartimento di Scienze della Salute
WNT Oncogenic Transcription Requires MYC Suppression of Lysosomal Activity and EPCAM Stabilization in Gastric Tumors
2024 P. Mulè, D. Fernandez-Perez, S. Amato, D. Manganaro, P. Oldani, S. Brandini, G. Diaferia, A. Cuomo, C. Recordati, C. Soriani, A. Dondi, M. Zanotti, S. Rustichelli, A. Bisso, S. Pece, S. Rodighiero, G. Natoli, B. Amati, K.J. Ferrari, F. Chiacchiera, D. Pasini
Dominant negative and directional dysregulation of Polycomb function inEZH2-mutant human growth disorders
2024 O. Deevy, C. Monger, F. Matrà, E. Tuck, E. Conway, S. Rodighiero, Q. Zhang, C. Davidovich, D. Pasini, A.P. Bracken
Navigating the complexity of Polycomb repression: Enzymatic cores and regulatory modules
2024 S. Tamburri, S. Rustichelli, S. Amato, D. Pasini
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1
2023 J.F. Thomas, M.I. Valencia-Sanchez, S. Tamburri, S.L. Gloor, S. Rustichelli, V. Godinez-Lopez, P. De Ioannes, R. Lee, S. Abini-Agbomson, K. Gretarsson, J.M. Burg, A.R. Hickman, L. Sun, S. Gopinath, H.F. Taylor, Z.-. Sun, R.J. Ezell, A. Vaidya, M.J. Meiners, M.A. Cheek, W.J. Rice, V. Svetlov, E. Nudler, C. Lu, M.-. Keogh, D. Pasini, K.-. Armache
PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1
2023 E. Glancy, C. Wang, E. Tuck, E. Healy, S. Amato, H.K. Neikes, A. Mariani, M. Mucha, M. Vermeulen, D. Pasini, A.P. Bracken
Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity
2023 S. Cascianelli, C. Barbera, A.A. Ulla, E. Grassi, B. Lupo, D. Pasini, A. Bertotti, L. Trusolino, E. Medico, C. Isella, M. Masseroli
Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis
2022 N. Tanaskovic, M. Dalsass, M. Filipuzzi, G. Ceccotti, A. Verrecchia, P. Nicoli, M. Doni, D. Olivero, D. Pasini, H. Koseki, A. Sabo, A. Bisso, B. Amati
BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
2021 E. Conway, F. Rossi, D. Fernandez-Perez, E. Ponzo, K.J. Ferrari, M. Zanotti, D. Manganaro, S. Rodighiero, S. Tamburri, D. Pasini
Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality
2021 N. Zaghet, K. Madsen, F. Rossi, D.F. Perez, P.G. Amendola, S. Demharter, U. Pfisterer, K. Khodosevich, D. Pasini, A.E. Salcini
Identification of a choroid plexus vascular barrier closing during intestinal inflammation
2021 S. Carloni, A. Bertocchi, S. Mancinelli, M. Bellini, M. Erreni, A. Borreca, D. Braga, S. Giugliano, A.M. Mozzarelli, D. Manganaro, D.F. Perez, F. Colombo, A. Di Sabatino, D. Pasini, G. Penna, M. Matteoli, S. Lodato, M. Rescigno
Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer
2021 S. Tamburri, E. Conway, D. Pasini
Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair
2021 B. Biferali, V. Bianconi, D.F. Perez, S.P. Kronawitter, F. Marullo, R. Maggio, T. Santini, F. Polverino, S. Biagioni, V. Summa, C. Toniatti, D. Pasini, S. Stricker, R.D. Fabio, F. Chiacchiera, G. Peruzzi, C. Mozzetta
Intestinal differentiation involves cleavage of histone H3 N-terminal tails by multiple proteases
2021 K.J. Ferrari, S. Amato, R. Noberini, C. Toscani, D. Fernández-Pérez, A. Rossi, P. Conforti, M. Zanotti, T. Bonaldi, S. Tamburri, D. Pasini
BAP1 activity regulates PcG occupancy and global chromatin condensation counteracting diffuse PCGF3/5-dependent H2AK119ub1 deposition
2020 E. Conway, F. Rossi, S. Tamburri, E. Ponzo, K.J. Ferrari, M. Zanotti, D. FERNANDEZ PEREZ, D. Manganaro, S. Rodighiero, D. Pasini
Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression
2020 S. Tamburri, E. Lavarone, D. Fernandez-Perez, E. Conway, M. Zanotti, D. Manganaro, D. Pasini
Cooperation between MYC and β-catenin in liver tumorigenesis requires Yap/Taz
2020 A. Bisso, M. Filipuzzi, G.P. Gamarra Figueroa, G. Brumana, F. Biagioni, M. Doni, G. Ceccotti, N. Tanaskovic, M.J. Morelli, V. Pendino, F. Chiacchiera, D. Pasini, D. Olivero, S. Campaner, A. Sabò, B. Amati
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype
2020 B. Lupo, F. Sassi, M. Pinnelli, F. Galimi, E.R. Zanella, V. Vurchio, G. Migliardi, P.A. Gagliardi, A. Puliafito, D. Manganaro, P. Luraghi, M. Kragh, M.W. Pedersen, I.D. Horak, C. Boccaccio, E. Medico, L. Primo, D. Nichol, I. Spiteri, T. Heide, A. Vatsiou, T.A. Graham, E. Elez, G. Argiles, P. Nuciforo, A. Sottoriva, R. Dienstmann, D. Pasini, E. Grassi, C. Isella, A. Bertotti, L. Trusolino
Dysfunctional polycomb transcriptional repression contributes to lamin A/C dependent muscular dystrophy
2020 A. Bianchi, C. Mozzetta, G. Pegoli, F. Lucini, S. Valsoni, V. Rosti, C. Petrini, A. Cortesi, F. Gregoretti, L. Antonelli, G. Oliva, M. De Bardi, R. Rizzi, B. Bodega, D. Pasini, F. Ferrari, C. Bearzi, C. Lanzuolo
PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin
2020 D. Musiani, R. Giambruno, E. Massignani, M.R. Ippolito, M. Maniaci, S. Jammula, D. Manganaro, A. Cuomo, L. Nicosia, D. Pasini, T. Bonaldi
Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities
2019 A. Scelfo, D. Fernandez-Perez, S. Tamburri, M. Zanotti, E. Lavarone, M. Soldi, T. Bonaldi, K.J. Ferrari, D. Pasini