IPPOLITO, MARICA ROSARIA
IPPOLITO, MARICA ROSARIA
Dipartimento di Oncologia ed Emato-Oncologia
High CDC20 levels increase sensitivity of cancer cells to MPS1 inhibitors
2025 S. Zheng, L. Raz, L. Zhou, Y. Cohen-Sharir, R. Tian, M.R. Ippolito, S. Gianotti, R. Saad, R. Wardenaar, M. Broekhuis, M. Suarez Peredo Rodriguez, S. Wobben, A. Van Den Brink, P. Bakker, S. Santaguida, F. Foijer, U. Ben-David
Sphingolipid synthesis maintains nuclear membrane integrity and genome stability during cell division
2025 S. Hwang, W. Russo, J. Cormier, J. Johnson, S. Martin, M.R. Ippolito, S. Cordone, R. Li, L.J. Zhu, S. Santaguida, E.M. Torres
Increased RNA and protein degradation is required for counteracting transcriptional burden and proteotoxic stress in human aneuploid cells
2024 M.R. Ippolito, J. Zerbib, Y. Eliezer, E. Reuveni, S. Vigano, G. De Feudis, E.D. Shulman, A. Savir Kadmon, R. Slutsky, T. Chang, E.M. Campagnolo, S. Taglietti, S. Scorzoni, S. Gianotti, S. Martin, J. Muenzner, M. Mulleder, N. Rozenblum, C. Rubolino, T. Ben-Yishay, K. Laue, Y. Cohen-Sharir, I. Vigorito, F. Nicassio, E. Ruppin, M. Ralser, F. Vazquez, S. Santaguida, U. Ben-David
A p62-dependent rheostat dictates micronuclei catastrophe and chromosome rearrangements
2024 S. Martin, S. Scorzoni, S. Cordone, A. Mazzagatti, G.V. Beznoussenko, A.L. Gunn, M. Di Bona, Y. Eliezer, G. Leor, T. Ben-Yishay, A. Loffreda, V. Cancila, M.C. Rainone, M.R. Ippolito, V. Martis, F. Bedin, M. Garrè, L.P. Vaites, P. Vasapolli, S. Polo, D. Parazzoli, C. Tripodo, A.A. Mironov, A. Cuomo, U. Ben-David, S.F. Bakhoum, E.M. Hatch, P. Ly, S. Santaguida
DECIPHERING AND EXPLOITING ANEUPLOIDY IN CANCER
2024 M.R. Ippolito
Generation of aneuploid cells and assessment of their ability to survive in presence of chemotherapeutic agents
2024 M.R. Ippolito, S. Santaguida
Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage
2024 J. Zerbib, M.R. Ippolito, Y. Eliezer, G. De Feudis, E. Reuveni, A. Savir Kadmon, S. Martin, S. Viganò, G. Leor, J. Berstler, J. Muenzner, M. Mülleder, E.M. Campagnolo, E.D. Shulman, T. Chang, C. Rubolino, K. Laue, Y. Cohen-Sharir, S. Scorzoni, S. Taglietti, A. Ratti, C. Stossel, T. Golan, F. Nicassio, E. Ruppin, M. Ralser, F. Vazquez, U. Ben-David, S. Santaguida
Short-term molecular consequences of chromosome mis-segregation for genome stability
2023 L. Garribba, G. De Feudis, V. Martis, M. Galli, M. Dumont, Y. Eliezer, R. Wardenaar, M.R. Ippolito, D.R. Iyer, A.E. Tijhuis, D.C.J. Spierings, M. Schubert, S. Taglietti, C. Soriani, S. Gemble, R. Basto, N. Rhind, F. Foijer, U. Ben-David, D. Fachinetti, Y. Doksani, S. Santaguida
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition
2021 Y. Cohen-Sharir, J.M. Mcfarland, M. Abdusamad, C. Marquis, S.V. Bernhard, M. Kazachkova, H. Tang, M.R. Ippolito, K. Laue, J. Zerbib, H.L.H. Malaby, A. Jones, L.-. Stautmeister, I. Bockaj, R. Wardenaar, N. Lyons, A. Nagaraja, A.J. Bass, D.C.J. Spierings, F. Foijer, R. Beroukhim, S. Santaguida, T.R. Golub, J. Stumpff, Z. Storchova, U. Ben-David
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
2021 M.R. Ippolito, V. Martis, S. Martin, A.E. Tijhuis, C. Hong, R. Wardenaar, M. Dumont, J. Zerbib, D.C.J. Spierings, D. Fachinetti, U. Ben-David, F. Foijer, S. Santaguida
PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin
2020 D. Musiani, R. Giambruno, E. Massignani, M.R. Ippolito, M. Maniaci, S. Jammula, D. Manganaro, A. Cuomo, L. Nicosia, D. Pasini, T. Bonaldi
Proteomics profiling of arginine methylation defines PRMT5 substrate specificity
2019 D. Musiani, J. Bok, E. Massignani, L. Wu, T. Tabaglio, M.R. Ippolito, A. Cuomo, U. Ozbek, H. Zorgati, U. Ghoshdastider, R.C. Robinson, E. Guccione, T. Bonaldi