SAPORITI, SIMONA
SAPORITI, SIMONA
Dipartimento di Scienze Farmacologiche e Biomolecolari
A new strategy for selective NOTCH2 targeting in multiple myeloma based on small molecules hampering receptor-ligand interaction
2017 N. Platonova, C. Parravicini, L. Palazzolo, S. Saporiti, M. Colombo, V. Vallelonga, R. Colella, F. Baccianti, A. Neri, I. Eberini, R. Chiaramonte
A new strategy of selective Notch receptor targeting in multiple myeloma based on small molecules
2018 N. Platonova, C. Parravicini, L. Palazzolo, S. Saporiti, M. Colombo, V. Vallelonga, D. Giannandrea, A. Neri, I. Eberini, R. Chiaramonte
A new therapeutic strategy in multiple myeloma based on small molecules directed to notch pathway
2018 N. Platonova, C. Parravicini, L. Palazzolo, S. Saporiti, M. Colombo, V. Vallelonga, D. Giannandrea, D. Giana, A. Neri, I. Eberini, R. Chiaramonte
An in silico structural approach to critical quality attributes assessment of biopharmaceutical products
2018 S. Saporiti, C. Parravicini, I. Eberini, F. Centola, C. Pergola, C. Sensi
Asn25 Deamidation as an Allosteric Tool to Increase IFNβ-1a Biological Activity
2022 E. Lipari, S. Saporiti, I. Eberini, L. Massimo, E. Mazzarella, G. Anderloni, M. Rossi, F. D'Amici, C. Pergola, W. Palinsky, C. Walter D'Acunto, F. Centola
Effect of Fc core fucosylation and light chain isotype on IgG1 flexibility
2023 S. Saporiti, T. Laurenzi, U. Guerrini, C. Coppa, W. Palinsky, G. Benigno, L. Palazzolo, O. Ben Mariem, L. Montavoci, M. Rossi, F. Centola, I. Eberini
Functional Heterodimerization between the G Protein-Coupled Receptor GPR17 and the Chemokine Receptors 2 and 4: New Evidence
2022 S. Daniele, S. Saporiti, S. Capaldi, D. Pietrobono, L. Russo, U. Guerrini, T. Laurenzi, E. Ataie Kachoie, L. Palazzolo, V. Russo, M.P. Abbracchio, I. Eberini, M.L. Trincavelli
IgG1 conformational behavior: elucidation of the N-glycosylation role via molecular dynamics
2022 S. Saporiti, C. Parravicini, C. Pergola, U. Guerrini, M. Rossi, F. Centola, I. Eberini
IgG1 conformational behavior: elucidation of the N-glycosylation role via molecular dynamics
2022 S. Saporiti, C. Parravicini, C. Pergola, U. Guerrini, M. Rossi, F. Centola, I. Eberini
IgG1 conformational behavior: elucidation of the N-glycosylation role via molecular dynamics
2021 S. Saporiti, C. Parravicini, C. Pergola, U. Guerrini, M. Rossi, F. Centola, I. Eberini
IgG1 Effecor functions: elucidation of glycans role by in silico structural analysis
2019 S. Saporiti, C. Parravicini, F. Centola, C. Pergola, I. Eberini
IgG1 effector functions: elucidation of glycans role by in silico structural analysis
2019 S. Saporiti, C. Parravicini, F. Centola, C. Pergola, I. Eberini
In silico identification of small molecules engaging the TNFR2-TNF-α interaction: a novel approach for targeting demyelinating diseases
2018 S. Saporiti, C. Parravicini, L. Palazzolo, R. Brambilla, I. Eberini
In silico identification of small molecules engaging the TNFR2-TNF-α interaction: a novel approach for targeting demyelinating diseases
2017 S. Saporiti, C. Parravicini, L. Palazzolo, R. Brambilla, I. Eberini
In silico investigation on structure–function relationship of members belonging to the human SLC52 transporter family
2022 O. Ben Mariem, S. Saporiti, U. Guerrini, T. Laurenzi, L. Palazzolo, C. Indiveri, M. Barile, E. De Fabiani, I. Eberini
In silico investigations of N-glycosylation role in modulating IgG1 conformational behavior and Fc effector functions
2021 S. Saporiti, C. Parravicini, C. Pergola, U. Guerrini, M. Rossi, F. Centola, I. Eberini
IN SILICO INVESTIGATIONS OF N-GLYCOSYLATION ROLE IN MODULATING IGG1 CONFORMATIONAL BEHAVIOR AND FC EFFECTOR FUNCTIONS
2020 S. Saporiti
Molecular Modelling of NONO and SFPQ Dimerization Process and RNA Recognition Mechanism
2022 T. Laurenzi, L. Palazzolo, E. Taiana, S. Saporiti, O. Ben Mariem, U. Guerrini, A. Neri, I. Eberini
New Notch-targeted therapeutic strategy to uncouple a pathological interaction of myeloma cells and bone marrow microenvironment using novel small molecules
2017 N. Platonova, C. Parravicini, L. Palazzolo, S. Saporiti, M. Colombo, V. Vallelonga, D. Colella R, B. F, A. Neri, I. Eberini, R. Chiaramonte
Notch-targeted therapeutic strategy in multiple myeloma based on small molecules hampering receptor-ligand interaction
2018 N. Platonova, C. Parravicini, L. Palazzolo, S. Saporiti, M. Colombo, V. Vallelonga, D. Giannandrea, D. Giana, A. Neri, I. Eberini, R. Chiaramonte