IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca

LECCA, DAVIDE
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 6.529
NA - Nord America 4.732
AS - Asia 2.508
SA - Sud America 119
OC - Oceania 67
AF - Africa 26
Continente sconosciuto - Info sul continente non disponibili 5
Totale 13.986
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 4.619
GB - Regno Unito 1.898
DE - Germania 1.510
CN - Cina 1.382
IT - Italia 1.332
SE - Svezia 507
IN - India 304
JP - Giappone 217
FR - Francia 198
IE - Irlanda 190
TR - Turchia 178
RU - Federazione Russa 141
FI - Finlandia 134
HK - Hong Kong 130
KR - Corea 125
UA - Ucraina 121
DK - Danimarca 113
CA - Canada 90
BE - Belgio 79
AU - Australia 63
NL - Olanda 53
ES - Italia 50
EU - Europa 49
CH - Svizzera 43
PL - Polonia 43
ID - Indonesia 41
GR - Grecia 38
BR - Brasile 35
CO - Colombia 34
SG - Singapore 34
TW - Taiwan 23
MX - Messico 22
UY - Uruguay 18
CL - Cile 17
AT - Austria 14
CZ - Repubblica Ceca 13
RO - Romania 12
IL - Israele 11
PT - Portogallo 11
IR - Iran 9
SC - Seychelles 9
VN - Vietnam 8
AR - Argentina 7
RS - Serbia 7
SA - Arabia Saudita 7
TH - Thailandia 7
PE - Perù 6
TN - Tunisia 6
HU - Ungheria 5
MY - Malesia 5
NO - Norvegia 5
NZ - Nuova Zelanda 4
PH - Filippine 4
PK - Pakistan 4
ZA - Sudafrica 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BY - Bielorussia 3
IQ - Iraq 3
KW - Kuwait 3
NG - Nigeria 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
AM - Armenia 2
BD - Bangladesh 2
BT - Bhutan 2
EC - Ecuador 2
EG - Egitto 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BZ - Belize 1
EE - Estonia 1
HR - Croazia 1
IM - Isola di Man 1
KE - Kenya 1
LK - Sri Lanka 1
MA - Marocco 1
MD - Moldavia 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
OM - Oman 1
UZ - Uzbekistan 1
Totale 14.033
Salva come PNG Salva come JPEG
Città #
Southend 1.596
Hanover 616
Milan 609
Chandler 419
Beijing 269
Fairfield 265
Wilmington 254
Frankfurt am Main 241
Princeton 234
Seattle 225
Ashburn 204
Houston 199
Ann Arbor 188
Dublin 186
Woodbridge 180
Sunnyvale 162
Dearborn 142
Redwood City 136
Berlin 130
Mountain View 130
Nanjing 120
Shanghai 120
Cambridge 113
Hong Kong 87
Redmond 87
Grafing 82
Des Moines 77
Bengaluru 67
Istanbul 57
Shenyang 56
Guangzhou 54
Phoenix 54
Boardman 52
Jacksonville 52
New York 50
Somerville 48
Tokyo 43
Helsinki 42
Serra 41
Brussels 38
Medford 37
Jinan 36
Andover 34
Turin 31
Hangzhou 30
San Diego 30
Bogotá 29
Changsha 29
Athens 28
Hebei 28
Nanchang 28
Paris 28
Sakarya 28
Hefei 27
Toronto 27
London 26
Chongqing 25
Warsaw 25
Bühl 24
Rome 24
Wuhan 24
Boston 22
Los Angeles 22
Minamiota 22
Tianjin 22
Zhengzhou 22
Melbourne 19
Ottawa 19
Denver 18
Falls Church 18
Kunming 17
Leipzig 17
Magenta 17
Ningbo 17
Silver Spring 17
Bonn 16
Chengdu 16
Jiaxing 16
Montevideo 16
Chicago 15
Eitensheim 15
Taipei 15
Odernheim 14
San Francisco 13
Taizhou 13
Fuzhou 12
San Jose 12
Seoul 12
Azzano San Paolo 11
Bitonto 11
Buffalo 11
Genova 11
Hamburg 11
Jakarta 11
Norwalk 11
Portsmouth 11
Singapore 11
Ferrara 10
Meda 10
Nuremberg 10
Totale 8.906
Salva come PNG Salva come JPEG
Nome #
Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine 960
SNX27, a protein involved in down syndrome, regulates GPR17 trafficking and oligodendrocyte differentiation 507
Regulation and signaling of the GPR17 receptor in oligodendroglial cells 468
The concise guide to pharmacology 2021/22 : G protein-coupled receptors 424
The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization 347
Improvement of fiber connectivity and functional recovery after stroke by montelukast, an available and safe anti-asthmatic drug 330
CNS remyelination as a novel reparative approach to neurodegenerative diseases : The roles of purinergic signaling and the P2Y-like receptor GPR17 310
In vivo silencing of miR-125a-3p promotes myelin repair in models of white matter demyelination 302
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair 275
Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination 254
Opposite effects of uracil and adenine nucleotides on the survival of murine cardiomyocytes 240
Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis 223
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor 209
Coinvolgimento di GPR17, un nuovo recettore duale per nucleotidi extracellulari e cistenil-leucotrieni, nell'ischemia cerebrale 196
Purple Corn Extract as Anti-allodynic Treatment for Trigeminal Pain : Role of Microglia 189
Dysregulation of GPR17, a key receptor involved in oligodendrocyte maturation, as a novel potential pathogenetic mechanism in demyelinating diseases 179
Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor 173
Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis 170
MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis 167
A role for the P2Y-like GPR17 receptor in oligodendrocyte differentiation 156
The P2Y-like GPR17 receptor orchestrates the transition between immature and myelinating oligodendrocytes and is a new target for myelin repair 156
A new role for the P2Y-like GPR17 receptor in the modulation of multipotency of oligodendrocyte precursor cells in vitro 152
The Concise Guide to Pharmacology 2019/20: G protein-coupled receptors 149
Corn (ZEA MAYS L). extracts as source of active compounds with promising effects in reducing trigeminal pain through microbiota modulation 148
MicroRNAs change the games in central nervous system pharmacology 146
Purinergic receptors on oligodendrocyte progenitors : promising targets for myelin repair in multiple sclerosis? 144
The Distribution of GPR17-Expressing Cells Correlates with White Matter Inflammation Status in Brain Tissues of Multiple Sclerosis Patients 144
Different properties of P2X(7) receptor in hippocampal and cortical astrocytes 143
Expression pattern and distribution of the oligodendroglial receptor GPR17 in Experimental Autoimmune Encephalomyelitis, a mouse model of Multiple Sclerosis 140
Pathway-Focused Profiling of Oligodendrocytes Over-Expressing miR-125a-3p Reveals Alteration of Wnt and Cell-to-Cell Signaling 136
Novel in vitro experimental approaches to study myelination and remyelination in the central nervous system 135
The expression and intracellular trafficking of the P2Y-like receptor GPR17 in oligodendroglial cells 134
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview 134
Stimulation of P2Y-like receptor GPR17 by both uracil nucleotides and cysteinyl-leukotrienes increases outward potassium currents in 1321N1 cells 131
Deorphanisation of G protein-coupled receptors : a tool to provide new insights in nervous system pathophysiology and new targets for psycho-active drugs 126
Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells 124
Expression pattern of GPR17, a dual receptor for uracil nucleotides and cysteinyl-leukotrienes, during brain ischemia in mice 122
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1 122
The P2Y-like receptor GPR17 as a sensor of damage and a target of CNS repair 119
Lupin Peptide T9 (GQEQSHQDEGVIVR) Modulates the Mutant PCSK9D374Y Pathway : in vitro Characterization of its Dual Hypocholesterolemic Behavior 119
Opposte effects of uracil and adenine nucleotides on the survival of murine cardiomyocytes 118
Microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor 117
Dysregulation of GPR17, a key receptor involved in NG2 progenitor cells differentiation to mature oligodendrocytes, as a novel potential pathogenetic mechanism in demyelinating diseases 115
Mir-125a-3p negatively regulates oligodendrocyte precursor cells maturation and is altered in human multiple sclerosis 115
Agonist-induced desensitization/resensitization of human GPR17 : a functional cross-talk between purinergic and cysteinyl-leukotriene ligands 114
Regulation of oligodendrocyte functions : targeting lipid metabolism and extracellular matrix for myelin repair 113
Pharmacological and biotechnological in vitro approaches unveil the role of GPR17 signaling in regulating the timing of oligodendroglial differentiation 111
Extracellular purine and pyrimidine nucleotides as local extrinsic regulators of adult neural progenitor cells in the diseased CNS 110
Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways? 107
Dysregulation of the GPR17 receptor in neuroinflammatory diseases: implications for remyelination in multiple sclerosis 105
Uracil nucleotides : from metabolic intermediates to neuroprotection and neuroinflammation 103
Involvement of GPR17, a dual receptor for uracil nucleotides and cysteinyl-leukotrienes, in brain ischemia in mice 102
Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury 102
Local dysregulation of the GPR17 receptor in neuroinflammatory diseases: implications for remyelination in multiple sclerosis 102
Frontal Affinity Chromatography-Mass Spectrometry Useful for Characterization of New Ligands for GPR17 Receptor 101
Role of the P2Y-like receptor GPR17 in neural precursor cells 101
GPR17-expressing oligodendrocyte precursor cells differentially react to damage in experimental autoimmune encephalomyelitis and cuprizone-induced demyelination 101
Purinergic transmission in brain tumors and its impact on drug development 100
The oral reversibly-binding antiplatelet agent, Ticagrelor, acts as an antagonist at the P2Y-like receptor GPR17 99
Biotechnological and pharmacological in vitro approaches unveil the role of GPR17 signaling in regulating the timing of oligodendroglial differentiation 99
Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases 99
Gene regulation of the P2Y-like receptor GPR17, a key player in oligodendroglial differentiation 98
Gene regulation of the P2Y-like receptor GPR17 in oligodendrocytes, and pathological alterations in a mouse model of multiple sclerosis 97
New mechanisms regulating myelination in the central nervous system : the role of GPR17 and of a novel micro-RNA 97
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors 95
Functional cross-talk between GPR17 and nerve growth factor in neuronal pheocromocytoma PC12 cell proliferation and differentiation 94
The P2Y-like GPR17 receptor orchestrates the transition between immature and myelinating oligodendrocytes and is a new target for myelin repair 94
Role of purinergic signalling in neuro-immune cells and adult neural progenitors 94
Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation 94
The P2Y-like GPR17 receptor regulates the differentiation of NG2+ neural precursor cells into mature oligodendrocytes 94
Gene regulation of the receptor GPR17 in oligodendroglial cells: expression pattern and pathological alterations in a mouse model of multiple sclerosis 94
SNX27 regulates GPR17 recycling and the kinetics of oligodendrocyte differentiation 94
GPR17, a key receptor involved in oligodendrogenesis: implications for re-myelination strategies 93
The mammalian target of rapamycin (mTOR) controls oligodendrocyte maturation by fine-tuning the activity of GPR17 receptor via G protein-coupled receptor kinases 90
Promoting re-myelination in MS via the GPR17 receptor, a new key actor in oligodendrogenesis 89
GPR17 ligands : synthesis and characterization of new potent agonists 88
SNX27 regulation of GPR17 recycling is important for the correct differentiation of oligodendrocytes 87
Regulation of PC12 cell survival and differentiation by the new P2Y-like receptor GPR17 86
SNX27, a protein of the retromer complex, regulates GPR17 recycling and the kinetics of oligodendrocyte differentiation 86
The P2Y-like receptor GPR17 as a potential target for the modulation of adult oligodendrogliogenesis 85
Time-dependent and critical role of the P2Y-like GPR17 receptor at distinct stages of oligodendrocyte differentiation 85
Purinergic and cysteinyl-leukotriene agonists of the GPR17 receptor engender distinct intracellular signalling programs with different functional potentials in oligodendrocyte maturation 85
Time-dependent and critical role of the P2Y-like GPR17 receptor at distinct stages of oligodendrocyte differentiation 84
Identification of CRYAB+ KCNN3+ SOX9+ Astrocyte-Like and EGFR+ PDGFRA+ OLIG1+ Oligodendrocyte-Like Tumoral Cells in Diffuse IDH1-Mutant Gliomas and Implication of NOTCH1 Signalling in Their Genesis 83
In search of signals that trigger GPR17 expression in microglia cells 82
A PDZ binding motif controls G protein-coupled receptor 17 trafficking in differentiating oligodendrocytes 82
Oligodendrogenesis: focus on G protein-coupled receptor 17 (GPR17) 82
Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor 80
Identification of molecular mechanisms underlying oligodendrocyte differentiation 77
Role of the P2Y-like receptor in neural precursor cells 76
The genetic inhibition of GPR17 affects myelination by influencing important players in oligodendrocyte maturation, including purinergic receptors 76
A new miRNA regulating oligodendrocyte maturation in physiology and disease 76
Agonist-induced desensitisation/resensitisation of human GPR17: a functional cross talk between purinergic and cysteinyl-leukotriene ligands 76
Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death 75
P2Y receptors in GtoPdb v.2021.3 74
P2Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database 72
Ventral tegmental area/substantia nigra and prefrontal cortex rodent organotypic brain slices as an integrated model to study the cellular changes induced by oxygen/glucose deprivation and reperfusion : effect of neuroprotective agents 69
Gene regulation of GPR17, a checkpoint receptor in oligodendroglial differentiation 68
The Regulated Expression, Intracellular Trafficking, and Membrane Recycling of the P2Y-like Receptor GPR17 in Oli-neu Oligodendroglial Cells 66
Expression pattern of the G protein-coupled receptor GPR17 after traumatic brain injury in human subjects 66
Totale 14.320
Salva come PNG Salva come JPEG
Categoria #
all - tutte 37.072
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.072
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019195 0 0 0 0 0 0 0 0 0 0 81 114
2019/20201.756 194 70 74 161 117 216 218 109 233 204 84 76
2020/20211.966 131 121 99 66 171 193 101 138 263 213 374 96
2021/20222.781 185 124 121 147 256 231 284 200 196 384 300 353
2022/20232.101 308 169 199 224 209 358 60 121 225 39 106 83
2023/20241.597 89 98 164 192 348 138 102 208 103 146 9 0
Totale 14.884