Berries represent an important source of bioactive compounds, among which, (poly)phenols are the main constituents. (Poly)phenols have been shown to have important biological activities and in particular, to take a relevant role in mediating the modulation of gut microbiota and human health. Gut microbiota constitute significant players in the metabolism of ingested (poly)phenols and consequently in their biological effects. However, the evidence regarding the mutual contribution between (poly)phenol intake and gut microbiota activity in humans is still unclear. The aim of the current systematic review was to collect and assess results from randomized clinical trials addressing the role of berries in the modulation of the gut microbiota composition and how this can contribute to the metabolism of berry (poly)phenols. When information was available, the interaction of berry-gut microbiota on human health was evaluated. A total of 16 trials were included and analyzed. Overall, berries and their (poly)phenols could represent a driver for the modulation of intestinal microbes. The gut microbiota catabolize (poly)phenols by producing bioactive metabolites which can positively affect both the composition of commensal microbiota and also the host health.

Berries-Gut Microbiota Interaction and Impact on Human Health: A Systematic Review of Randomized Controlled Trials / M. Marino, S. Venturi, G. Gargari, C. Del Bo, D. Martini, M. Porrini, S. Guglielmetti, P. Riso. - In: FOOD REVIEWS INTERNATIONAL. - ISSN 8755-9129. - (2023), pp. 1-23. [Epub ahead of print] [10.1080/87559129.2023.2276765]

Berries-Gut Microbiota Interaction and Impact on Human Health: A Systematic Review of Randomized Controlled Trials

M. Marino
Primo
;
S. Venturi
Secondo
;
G. Gargari
;
C. Del Bo
;
D. Martini;M. Porrini;S. Guglielmetti;P. Riso
Ultimo
2023

Abstract

Berries represent an important source of bioactive compounds, among which, (poly)phenols are the main constituents. (Poly)phenols have been shown to have important biological activities and in particular, to take a relevant role in mediating the modulation of gut microbiota and human health. Gut microbiota constitute significant players in the metabolism of ingested (poly)phenols and consequently in their biological effects. However, the evidence regarding the mutual contribution between (poly)phenol intake and gut microbiota activity in humans is still unclear. The aim of the current systematic review was to collect and assess results from randomized clinical trials addressing the role of berries in the modulation of the gut microbiota composition and how this can contribute to the metabolism of berry (poly)phenols. When information was available, the interaction of berry-gut microbiota on human health was evaluated. A total of 16 trials were included and analyzed. Overall, berries and their (poly)phenols could represent a driver for the modulation of intestinal microbes. The gut microbiota catabolize (poly)phenols by producing bioactive metabolites which can positively affect both the composition of commensal microbiota and also the host health.
No
English
Berries; Polyphenols; Gut microbiota; Microbiome; Metabolism; Human health
Settore MED/49 - Scienze Tecniche Dietetiche Applicate
Articolo
Esperti anonimi
Pubblicazione scientifica
   MIND FoodS HUB
   REGIONE LOMBARDIA

   One Health Action Hub: task force di Ateneo per la resilienza di ecosistemi territoriali (1H_Hub) Linea Strategica 3, Tema One health, one earth
   1H_Hub
   UNIVERSITA' DEGLI STUDI DI MILANO
2023
5-nov-2023
Taylor & Francis Online
1
23
23
Epub ahead of print
Periodico con rilevanza internazionale
https://www.tandfonline.com/doi/abs/10.1080/87559129.2023.2276765
scopus
crossref
Aderisco
info:eu-repo/semantics/article
Berries-Gut Microbiota Interaction and Impact on Human Health: A Systematic Review of Randomized Controlled Trials / M. Marino, S. Venturi, G. Gargari, C. Del Bo, D. Martini, M. Porrini, S. Guglielmetti, P. Riso. - In: FOOD REVIEWS INTERNATIONAL. - ISSN 8755-9129. - (2023), pp. 1-23. [Epub ahead of print] [10.1080/87559129.2023.2276765]
reserved
Prodotti della ricerca::01 - Articolo su periodico
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262
Article (author)
Periodico con Impact Factor
M. Marino, S. Venturi, G. Gargari, C. Del Bo, D. Martini, M. Porrini, S. Guglielmetti, P. Riso
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1018423
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