IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca

Validation of a new prognostic body composition parameter in cancer patients

HP2 Survey: V. Ophiuchus: Filament formation in a dispersing cloud complex

We searched for potential "birthmarks"left from the formation of filamentary molecular clouds in the Ophiuchus complex. We used high dynamic range column density and temperature maps derived from Herschel, Planck, and 2MASS/NICEST extinction data. We found two distinct types of filaments based on their orientation relative to nearby massive stars: radial (R-type) and tangential (T-type). R-type filaments exhibit decreasing mass profiles away from massive stars, while T-type filaments show fla...

Development of an HPLC–UV assay method for the simultaneous quantification of nine antiretroviral agents in the plasma of HIV-infected patients

A new method using high-performance liquid chromatography coupled with ultra violet detection (HPLC–UV) was developed and validated for the simultaneous quantification of atazanavir, dolutegravir, darunavir, efavirenz, etravirine lopinavir, raltegravir, rilpivirine and tipranavir in human plasma. For the first time we reported here the development and validation of an HPLC–UV assay to quantify the frequently administered 9 antiretroviral compounds including dolutegravir and rilpivirine. A sim...

Development of an Oral Delivery System for Ileo-Colonic Release of a Diospyros kaki leaf extract

Following the COVID-19 pandemic, interest in complementary approaches to disease prevention and health promotion has increased, particularly in nutraceuticals containing plant-derived bioactive compounds. Among these, polyphenols have attracted attention for their antioxidant, anti-inflammatory and immunomodulatory properties, as well as for their positive impact on the gut microbiota1. Diospyros kaki (DK), particularly its leaves, is a promising source of flavonoids and condensed tannins. Ho...