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Prodotti recenti

The effect of recall period on reported out-of-pocket health expenditure in Ghana

Background Out-of-pocket health payments (OOPs) are a key indicator of health financing systems’ performance. Measuring OOPs through household surveys is challenging and yet it is the primary source of information in the absence of comprehensive data on user charges in the public sector and market data from the private sector. The choice of the recall period has been identified as a source of bias in previous studies. This study investigates the effect of two different types of recall periods...

Spatiotemporal Trends in Stunting Prevalence Among Children Aged Two Years Old in Rwanda (2020–2024): A Retrospective Analysis

Background and Objective: Stunting remains a critical public health concern affecting child growth and development, particularly among children under two years of age in low- and middle-income countries, including Rwanda. This study investigates spatiotemporal trends in stunting prevalence from 2020 to 2024 at the sector level using national surveillance data. Methods: To capture regional disparities and temporal trends, we used hierarchical Bayesian spatiotemporal models, which accounted for...

Prognostic Impact of Osteopenia in Patients with Resectable Esophageal Adenocarcinoma: A Retrospective Study

IntroductionOsteopenia, marked by low bone mineral density, is a sign of patient frailty and has been linked to poor survival in patients with esophageal squamous cell carcinoma. However, its impact on overall survival (OS) and disease-free survival (DFS) in patients with esophageal adenocarcinoma is still unclear.AimOur aim was to assess the impact of osteopenia on long-term survival in patients with resectable esophageal adenocarcinoma.MethodsThis was a retrospective study (January 2014-Dec...

A multi-omics approach uncovers causality of IL6R on endotypes of subclinical carotid atherosclerosis and the possible role of the IL6R/OSMR pathway

Aims Endotypes integrate individual clinical and molecular data and can be used to formulate molecular subclassifications of diseases. We previously derived four endotypes of subclinical carotid atherosclerosis in a large European cohort, c-IMT and c-IMT Progression as Predictors of Vascular Events in a High-Risk European Population (IMPROVE), identifying individuals with a specific cardiovascular (CV) risk, ranging from low (endotype 1) to very high (endotype 4). Here, we investigate the mec...

Isolation and Characterization Through Whole-Genome Sequencing of STEC Strains from Free-Ranging Red Deer

Whole-genome sequence (WGS) analysis was used in this study to characterize Shiga toxin-producing Escherichia coli (STEC) isolates in free-ranging red deer from the central Italian Alps. Fecal samples from 92 hunted red deer collected between September and December 2022 were analyzed for the presence of STEC. Single E. coli colonies positive by PCR for stx genes were analyzed by WGS. STEC were isolated from eleven (12%) samples, showing eight stx2b, one stx2a, two stx1c, and one stx1a subtype...

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