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Prodotti della ricerca: [316170] Home page macrotipologia

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Prodotti recenti

A continuous calibration of the ATLAS flavour-tagging classifiers via optimal transportation maps

Photocatalytic addition of N‑Oxazolidinone radicals to arenes and heteroarenes in batch and in flow mode

Recent progress in N-centered radical chemistry has paved the way for unprecedented transformations in organic synthesis, particularly through photocatalytic C−N bond formation reactions. Here, unexplored N-oxazolidinone radicals are generated through visible light irradiation, enabling a novel, efficient, sustainable, and scalable C−H functionalization process of arenes and heteroarenes. Crucially, the use of continuous flow processing was found to provide further advantages over standard ba...

Short-term outcomes after lung transplantation using grafts preserved at 10 °c: A single-center study

Lung transplantation is constrained by donor shortages and logistical challenges. Standard cold storage at 4 °C limits metabolism but can cause cold-induced injury. Preservation at 10 °C may better maintain cellular integrity and extend preservation time. This study evaluated the clinical safety and short-term effectiveness of lung graft preservation at 10 °C within the Italian regulatory framework. A single-center, prospective comparative cohort study included adult recipients of bilateral l...

Multiple and Alternative Sites Make Tau Protein an Adaptable Sticky Surface for the SH3 Domain of Fyn Kinase

The interaction between the microtubule associated protein Tau and the tyrosine kinase Fyn is believed to play a pivotal role in the early stage of Alzheimer's disease. Previous studies have identified the SRC Homology 3 (SH3) domain of Fyn as the binding receptor of several proline-rich motifs in Tau. However, the role of each proline-rich motif and their interplay in molecular recognition are still unclear. In this work, we investigated the mechanism of Fyn-SH3 recognition by the multiple P...

Real-time brain tumor detection in intraoperative ultrasound: From model training to deployment in the operating room

Intraoperative ultrasound (ioUS) is a valuable tool in brain tumor surgery due to its versatility, affordability, and seamless integration into the surgical workflow. However, its adoption remains limited, primarily because of the challenges associated with image interpretation and the steep learning curve required for effective use. This study aimed to enhance the interpretability of ioUS images by developing a real-time brain tumor detection system deployable in the operating room. We colle...

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