COSSU, FEDERICA
COSSU, FEDERICA
Dipartimento di Bioscienze
CHCHD4 binding affects the active site of apoptosis inducing factor (AIF): Structural determinants for allosteric regulation
2024 E. Fagnani, P. Cocomazzi, S. Pellegrino, G. Tedeschi, F.G. Scalvini, F. Cossu, S. Da Vela, A. Aliverti, E. Mastrangelo, M. Milani
Ligand Binding in Allosteric Flavoproteins: Part 1. Quantitative Analysis of the Interaction with NAD+ of the Apoptosis Inducing Factor (AIF) Harboring FAD in the Reduced State
2021 P. Cocomazzi, L. Sorrentino, F. Cossu, A. Aliverti
Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs
2018 A. Corti, M. Milani, D. Lecis, P. Seneci, M. de Rosa, E. Mastrangelo, F. Cossu
Structural bases of the altered functional properties of a pathological variant of the apoptosis inducing factor (AIF)
2017 A. Aliverti, L. Sorrentino, F. Cossu, P.G. Cocomazzi, M. Milani, E. Mastrangelo
Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor
2017 L. Sorrentino, F. Cossu, M. Milani, A. Aliverti, E. Mastrangelo
Cellulose production is coupled to sensing of the pyrimidine biosynthetic pathway via c-di-GMP production by the DgcQ protein of Escherichia coli
2017 E. Rossi, S. Motta, A. Aliverti, F. Cossu, L. Gourlay, P. Mauri, P. Landini
New homo- and heretodimeric SMAC mimetic compound as apoptosis inducers
2013 P. Seneci, L. Belvisi, F. Cossu, D. Delia, C. Drago, D. Lecis, S. Maiorana, L.P. Manzoni, E. Mastrangelo, M. Milani De Mayo De Mari, P.M.C. Perego, F. Vasile
STRUCTURAL INSIGHTS INTO INHIBITOR OF APOPTOSIS PROTEINS RECOGNITION BY PRO-APOPTOTIC COMPOUNDS
2012 F. Cossu
Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent Smac-mimetic
2012 F. Cossu, M. Milani, P. Vachette, F. Malvezzi, S. Grassi, D. Lecis, D. Delia, C. Drago, P. Seneci, M. Bolognesi, E. Mastrangelo
Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II : Structural and biological characterization
2012 D. Lecis, E. Mastrangelo, L. Belvisi, M. Bolognesi, M. Civera, F. Cossu, M. De Cesare, D. Delia, C. Drago, G. Manenti, L. Manzoni, M. Milani, E. Moroni, P. Perego, D. Potenza, V. Rizzo, C. Scavullo, C. Scolastico, F. Servida, F. Vasile, P. Seneci
Recognition of Smac-mimetic compounds by the BIR domain of cIAP1
2010 F. Cossu, F. Malvezzi, G. Canevari, E. Mastrangelo, D. Lecis, D. Delia, P. Seneci, C. Scolastico, M. Bolognesi, M. Milani
Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP Protein Family
2009 F. Cossu, M. Milani, E. Mastrangelo, P. Vachette, F. Servida, D. Lecis, G. Canevari, D. Delia, C. Drago, V. Rizzo, L. Manzoni, P. Seneci, C. Scolastico, M. Bolognesi
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy
2009 P. Seneci, A. Bianchi, C. Battaglia, L. Belvisi, M. Bolognesi, A. Caprini, F. Cossu, E. Franco, M. DE MATTEO, D. Delia, C. Drago, A. Khaled, D. Lecis, L. Manzoni, M. Marizzoni, E. Mastrangelo, M. Milani, I. Motto, E. Moroni, D. Potenza, V. Rizzo, F. Servida, E. Turlizzi, M. Varrone, F. Vasile, C. Scolastico
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
2009 F. Cossu, E. Mastrangelo, M. Milani, G. Sorrentino, D. Lecis, D. Delia, L. Manzoni, P. Seneci, C. Scolastico, M. Bolognesi
Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles
2008 E. Mastrangelo, F. Cossu, M. Milani, G. Sorrentino, D. Lecis, D. Delia, L. Manzoni, C. Drago, P. Seneci, C. Scolastico, V. Rizzo, M. Bolognesi