MANZONI, LEONARDO PIERPAOLO
MANZONI, LEONARDO PIERPAOLO
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
2020 L. Muzio, R. Sirtori, D. Gornati, S. Eleuteri, A. Fossaghi, D. Brancaccio, L. Manzoni, L. Ottoboni, L.D. Feo, A. Quattrini, E. Mastrangelo, L. Sorrentino, E. Scalone, G. Comi, L. Marinelli, N. Riva, M. Milani, P. Seneci, G. Martino
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors
2018 L. Manzoni, C. Zucal, D.D. Maio, V.G. D'Agostino, N. Thongon, I. Bonomo, P. Lal, M. Miceli, V. Baj, M. Brambilla, L. Cerofolini, S. Elezgarai, E. Biasini, C. Luchinat, E. Novellino, M. Fragai, L. Marinelli, A. Provenzani, P. Seneci
4-Connected azabicyclo[5.3.0]decane Smac mimetics-Zn2+ chelators as dual action antitumoral agents
2017 L.P. Manzoni, A. Samela, S. Barbini, S. Cairati, M. Penconi, D. Arosio, D. Lecis, P. Seneci
Regulation of HuR structure and function by dihydrotanshinone-I
2017 P. Lal, L. Cerofolini, V.G. D'Agostino, C. Zucal, C. Fuccio, I. Bonomo, E. Dassi, S. Giuntini, D. Di Maio, V. Vishwakarma, R. Preet, S.N. Williams, M.S. Fairlamb, R. Munk, E. Lehrmann, K. Abdelmohsen, S.R. Elezgarai, C. Luchinat, E. Novellino, A. Quattrone, E. Biasini, L. Manzoni, M. Gorospe, D.A. Dixon, P. Seneci, L. Marinelli, M. Fragai, A. Provenzani
Dual action Smac mimetics-zinc chelators as pro-apoptotic antitumoral agents
2016 L. Manzoni, D. Gornati, M. Manzotti, S. Cairati, A. Bossi, D. Arosio, D. Lecis, P. Seneci
Synthesis of dual action Smac/Zinc-Chelator conjugates as putative proapoptotic agents
2016 D. Gornati, L. Manzoni, D. Arosio, D. Lecis, P. Seneci
Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions
2015 F. Doro, C. Colombo, C. Alberti, D. Arosio, L. Belvisi, C. Casagrande, R. Fanelli, L. Manzoni, E. Parisini, U. Piarulli, E. Luison, M. Figini, A. Tomassetti, M. Civera
Design and synthesis of peptidomimetic molecules targeting cadherin-mediated protein-protein interactions
2012 C. Colombo, C. Alberti, D. Arosio, L. Belvisi, F. Doro, L. Manzoni, M. Civera
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib
2010 D. Lecis, C. Drago, L. Manzoni, P. Seneci, C. Scolastico, E. Mastrangelo, M. Bolognesi, A. Anichini, H. Kashkar, H. Walczak, D. Delia
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
2009 F. Cossu, E. Mastrangelo, M. Milani, G. Sorrentino, D. Lecis, D. Delia, L. Manzoni, P. Seneci, C. Scolastico, M. Bolognesi
Cyclic RGD-containing functionalized azabicycloalkane peptides as potent integrin antagonists for tumor targeting
2009 L. Manzoni, L. Belvisi, D. Arosio, M. Civera, M. Pilkington-Miksa, D. Potenza, A. Caprini, E.M.V. Araldi, E. Monferini, M. Mancino, F. Podestà, C. Scolastico
New SMAC mimetic compounds as apoptosis inducers
2009 C. Scolastico, L.P. Manzoni, P. Seneci, L. Belvisi, D. Delia, M. Bolognesi, E. Mastrangelo, M. De Mayo De Mari Milani, I.M. Motto, C. Drago
Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP Protein Family
2009 F. Cossu, M. Milani, E. Mastrangelo, P. Vachette, F. Servida, D. Lecis, G. Canevari, D. Delia, C. Drago, V. Rizzo, L. Manzoni, P. Seneci, C. Scolastico, M. Bolognesi
Cyclic RGD peptides containing azabicycloalkane reverse-turn mimics
2002 L. Belvisi, A. Caporale, M. Colombo, L. Manzoni, D. Potenza, C. Scolastico, M. Castorina, M. Cati, G. Giannini, C. Pisano
Practical stereoselective synthesis of conformationally constrained unnatural proline-based amino acids and peptidomimetics
2001 L. Belvisi, L. Colombo, M. Colombo, M. Di Giacomo, L. Manzoni, B. Vodopivec, C. Scolastico
Potent integrin antagonists from a small library of RGD-including cyclic pseudopeptides
2001 L. Belvisi, A. Bernardi, A. Checchia, L. Manzoni, D. Potenza, C. Scolastico, M. Castorina, A. Cupelli, G. Giannini, P. Carminati, C. Pisano
Conformational analysis of azabicycloalkane amino acid scaffolds as reverse-turn inducer dipeptide mimics
2000 L. Belvisi, A. Bernardi, L. Manzoni, D. Potenza, C. Scolastico
Synthesis of 8,5-fused bicyclic lactam by stereo- and regioselective radical cyclization
2000 L. Manzoni, L. Belvisi, C. Scolastico
Stereoselective synthesis of 6,5-bicyclic reverse-turn peptidomimetics
1998 L. Colombo, M. Di Giacomo, G. Brusotti, N. Sardone, M. Angiolini, L. Belvisi, S. Maffioli, L. Manzoni, C. Scolastico
Synthesis of Lewis A and Lewis X pentasaccharides based on N-trichloroethoxycarbonyl protection
1998 L. Manzoni, L. Lay, R.R. Schmidt