Pasteurized donor human milk (PDHM) for preterm infant nutrition is fortiﬁed with hydrolyzates of cow’s milk proteins, which have been poorly investigated in relation to heat-damage and occurrence of the bioactive peptides β-casomorphins (BCMs). Therefore, thermal protein modiﬁcations of three commercial fortiﬁers were assessed by measuring well-recognized indexes of heat load. The fortiﬁers did not contain pyrraline, whereas furosine and lysinoalanine levels roughly overlapped the lowest values reported for liquid formulas addressed to term infant nutrition. Bovine BCMs 3 to 7 and human BCMs 3 to 9 were searched. Bovine BCMs 3, 4, 6 and 7 were found in the undigested fortiﬁers. Following in vitro digestion simulating the digestive conditions of pre- mature infant, bovine BCMs still occurred in fortiﬁed PDHM; the human BCMs 3, 7, 8 and 9 formed. Overall, these results better address the nutritional features of protein fortiﬁers and fortiﬁed PDHM intended for nutrition of preterm infants.
Effect of protein fortification on heat damage and occurrence of beta-casomorphins in (un)digested donor human milk intended for nutrition of preterm infants / S. Cattaneo, V. Pica, M. Stuknytė, F. Masotti, D. Mallardi, C. Tabasso, P. Roggero, I. De Noni. - In: FOOD CHEMISTRY. - ISSN 0308-8146. - 314(2020 Jun 01), pp. 126176.1-126176.8.
|Titolo:||Effect of protein fortification on heat damage and occurrence of beta-casomorphins in (un)digested donor human milk intended for nutrition of preterm infants|
CATTANEO, STEFANO (Primo)
PICA, VALENTINA (Secondo)
DE NONI, IVANO (Ultimo) (Corresponding)
|Parole Chiave:||Preterm infant; Milk protein hydrolyzates; Heat damage; Casomorphins; Digestion|
|Settore Scientifico Disciplinare:||Settore AGR/15 - Scienze e Tecnologie Alimentari|
|Data di pubblicazione:||1-giu-2020|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.foodchem.2020.126176|
|Appare nelle tipologie:||01 - Articolo su periodico|