SIGISMUND, SARA LUCIA GIUSTINA
SIGISMUND, SARA LUCIA GIUSTINA
Dipartimento di Oncologia ed Emato-Oncologia
A NUMB-EFA6B-ARF6 recycling route controls apically restricted cell protrusions and mesenchymal motility
2018 M. Zobel, A. Disanza, F. Senic-Matuglia, M. Franco, I.N. Colaluca, S. Confalonieri, S. Bisi, E. Barbieri, G. Caldieri, S. Sigismund, S. Pece, P. Chavrier, P.P. Di Fiore, G. Scita
A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior
2020 I. Schiano Lomoriello, G. Giangreco, C. Iavarone, C. Tordonato, G. Caldieri, G. Serio, S. Confalonieri, S. Freddi, F. Bianchi, S. Pirroni, G. Bertalot, G. Viale, D. Disalvatore, D. Tosoni, M.G. Malabarba, A. Disanza, G. Scita, S. Pece, B.K. Pilcher, M. Vecchi, S. Sigismund, P.P. Di Fiore
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins
2002 S. Polo, S. Sigismund, M. Faretta, M. Guidi, M.R. Capua, G. Bossi, H. Chen, P. De Camilli, P.P. Di Fiore
Clathrin-independent endocytosis of ubiquitinated cargos
2005 S. Sigismund, T. Woelk, C. Puri, E. Maspero, C. Tacchetti, P. Transidico, P.P. Di Fiore, S. Polo
Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation
2008 S. Sigismund, E. Argenzio, D. Tosoni, E. Cavallaro, S. Polo, P.P. Di Fiore
EGFR Trafficking in Physiology and Cancer
2018 G. Caldieri, M.G. Malabarba, P.P. Di Fiore, S. Sigismund
Emerging functions of the EGFR in cancer
2018 S. Sigismund, D. Avanzato, L. Lanzetti
Endocytic control of signaling at the plasma membrane
2016 E. Barbieri, P.P. Di Fiore, S. Sigismund
Endocytosis and signaling: cell logistics shape the eukaryotic cell plan
2012 S. Sigismund, S. Confalonieri, A. Ciliberto, S. Polo, G. Scita, P.P. Di Fiore
Endocytosis in the context-dependent regulation of individual and collective cell properties
2021 S. Sigismund, L. Lanzetti, G. Scita, P.P. Di Fiore
Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma
2012 C. Garofalo, C. Mancarella, A. Grilli, M.C. Manara, A. Astolfi, M.T. Marino, A. Conte, S. Sigismund, A. Carè, A. Belfiore, P. Picci, K. Scotlandi
Keeping EGFR signaling in check : Ubiquitin is the guardian
2014 S. Polo, P.P. Di Fiore, S. Sigismund
Ligand-induced EGF receptor oligomerization is kinase-dependent and enhances internalization
2010 E.G. Hofman, A.N. Bader, J. Voortman, D.J. Van Den Heuvel, S. Sigismund, A.J. Verkleij, H.C. Gerritsen, P.M.P. Van Bergen en Henegouwen
Methods to investigate EGFR ubiquitination
2017 A. Conte, S. Sigismund
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function
2017 F. Gulluni, M. Martini, M.C. De Santis, C.C. Campa, A. Ghigo, J.P. Margaria, E. Ciraolo, I. Franco, U. Ala, L. Annaratone, D. Disalvatore, G. Bertalot, G. Viale, A. Noatynska, M. Compagno, S. Sigismund, F. Montemurro, M. Thelen, F. Fan, P. Meraldi, C. Marchiã², S. Pece, A. Sapino, R. Chiarle, P.P. Di Fiore, E. Hirsch
Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling
2019 R. Pascolutti, V. Algisi, A. Conte, A. Raimondi, M. Pasham, S. Upadhyayula, R. Gaudin, T. Maritzen, E. Barbieri, G. Caldieri, C. Tordonato, S. Confalonieri, S. Freddi, M.G. Malabarba, E. Maspero, S. Polo, C. Tacchetti, V. Haucke, T. Kirchhausen, P.P. Di Fiore, S. Sigismund
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
2003 K. Haglund, S. Sigismund, S. Polo, I. Szymkiewicz, P. P. Di Fiore, I. Dikic
Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo
2012 F. Orsenigo, C. Giampietro, A. Ferrari, M. Corada, A. Galaup, S. Sigismund, G. Ristagno, L. Maddaluno, G. Young Koh, D. Franco, V. Kurtcuoglu, D. Poulikakos, P. Baluk, D. Mcdonald, M.G. Lampugnani, E. Dejana
PillarX: A Microfluidic Device to Profile Circulating Tumor Cell Clusters Based on Geometry, Deformability, and Epithelial State
2022 B.J. Green, M. Marazzini, B. Hershey, A. Fardin, Q. Li, Z. Wang, G. Giangreco, F. Pisati, S. Marchesi, A. Disanza, E. Frittoli, E. Martini, S. Magni, G.V. Beznoussenko, C. Vernieri, R. Lobefaro, D. Parazzoli, P. Maiuri, K. Havas, M. Labib, S. Sigismund, P.P.D. Fiore, R.H. Gunby, S.O. Kelley, G. Scita
Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells
2015 F. Capuani, A. Conte, E. Argenzio, L. Marchetti, C. Priami, S. Polo, P.P. Di Fiore, S. Sigismund, A. Ciliberto