SAPONARO, ANDREA COSIMO
SAPONARO, ANDREA COSIMO
Dipartimento di Bioscienze
A functional K+ channel from tetraselmis virus 1, a member of the mimiviridae
2020 K. Kukovetz, B. Hertel, C.R. Schvarcz, A. Saponaro, M. Manthey, U. Burk, T. Greiner, G.F. Steward, J.L. van Etten, A. Moroni, G. Thiel, O. Rauh
A light-gated potassium channel for sustained neuronal inhibition
2018 L. Alberio, A. Locarno, A. Saponaro, E. Romano, V. Bercier, S. Albadri, F. Simeoni, S. Moleri, S. Pelucchi, A. Porro, E. Marcello, N. Barsotti, K. Kukovetz, A.J. Boender, A. Contestabile, S. Luo, A. Moutal, Y. Ji, G. Romani, M. Beltrame, F. Del Bene, M. Di Luca, R. Khanna, H.M. Colecraft, M. Pasqualetti, G. Thiel, R. Tonini, A. Moroni
A reduced mechanical model for cAMP-modulated gating in HCN channels
2017 S. Weißgraeber, A. Saponaro, G. Thiel, K. Hamacher
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels
2018 A. Saponaro, F. Cantini, A. Porro, A. Bucchi, D. Difrancesco, V. Maione, C. Donadoni, B. Introini, P. Mesirca, M.E. Mangoni, G. Thiel, L. Banci, B. Santoro, A. Moroni
Assigning Function to the D and E Helices of HCN CNBD
2018 A. Saponaro, A. Porro, C. Donadoni, B. Santoro, G. Thiel, A. Moroni
Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMP
2013 L. Hu, B. Santoro, A. Saponaro, H. Liu, A. Moroni, S. Siegelbaum
Chimeric HCN Channels for Studying cAMP-Induced Conformational Changes in the C-Linker
2019 B. Introini, A. Saponaro, A. Bonicci, O. Rauh, F. Cantini, L. Banci, G. Thiel, A. Moroni
Cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4
2020 A. Porro, G. Thiel, A. Moroni, A.C. Saponaro
Detection of ligand binding to purified HCN channels using fluorescence-based size exclusion chromatography
2021 A. Saponaro, A.S. Sharifzadeh, A. Moroni
Developing Synthetic Peptides to Regulate Native HCN Channels
2019 A. Saponaro, F. Cantini, A. Porro, A. Bucchi, D. Difrancesco, V. Maione, M. Laskowski, P. Mesirca, M. Mangoni, G. Thiel, L. Banci, B. Santoro, A. Moroni
Exploring new pharmacological perspectives of Fusicoccin, a stabilizer of 14-3-3 – target protein complex
2017 A. Saponaro, A. Porro, A.C. Sanjuan, B. Introini, M. Nardini, G. Thiel, A. Moroni
Fusicoccin activates KAT1 channels by stabilizing their interaction with 14-3-3 proteins
2017 A. Saponaro, A. Porro, A. Chaves-Sanjuan, M. Nardini, O. Rauh, G. Thiel, A. Moroni
Gating movements and ion permeation in {HCN}4 pacemaker channels
2021 A.C. Saponaro, D. Bauer, M. Hunter Giese, P. Swuec, A. Porro, F. Gasparri, A. Sadat Sharifzadeh, A. CHAVES SANJUAN, L. Alberio, G. Parisi, G. Cerutti, O.B. Clarke, K. Hamacher, H.M. Colecraft, F. Mancia, W.A. Hendrickson, S.A. Siegelbaum, D. DI FRANCESCO, M. Bolognesi, G. Thiel, B. Santoro, A. Moroni
HCN Channels : the Molecular Basis for their cAMP-TRIP8b Regulation
2015 A.C. Saponaro, C. Donadoni, S.R. Pauleta, F. Cantini, M. Matzapetakis, G. Thiel, L. Banci, B. Santoro, A. Moroni
Isothermal Titration Calorimetry : A Biophysical Method to Characterize the Interaction between Label-free Biomolecules in Solution
2018 A.C. Saponaro
Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel
2018 C. Gross, A. Saponaro, B. Santoro, A. Moroni, G. Thiel, K. Hamacher
Protein Adsorption at the Air-Water Interface by a Charge Sensing Interferometric Technique
2019 P. Brocca, A. Saponaro, B. Introini, V. Rondelli, M. Pannuzzo, D. Raciti, M. Corti, A. Raudino
Rational design of a mutation to investigate the role of the brain protein TRIP8b in limiting the cAMP response of HCN channels in neurons
2020 A.C. Saponaro, A. Porro, A. Binda, I. Rivolta, M. Pisoni, C. Donadoni
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function
2014 A. Saponaro, S.R. Pauleta, F. Cantini, M. Matzapetakis, C. Hammann, C. Donadoni, L. Hu, G. Thiel, L. Banci, B. Santoro, A. Moroni
Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin
2020 V. Nardone, A. Chaves-Sanjuan, M. Lapi, C. Airoldi, A. Saponaro, S. Pasqualato, D. Dolfini, C. Camilloni, A. Bernardini, N. Gnesutta, R. Mantovani, M. Nardini