SAPONARO, ANDREA COSIMO
SAPONARO, ANDREA COSIMO
Dipartimento di Scienze Farmacologiche e Biomolecolari
A high affinity switch for cAMP in the HCN pacemaker channels
2024 A. Porro, A. Saponaro, R. Castelli, B. Introini, A.H. Alkotob, G. Ranjbari, U. Enke, J. Kusch, K. Benndorf, B. Santoro, D. Difrancesco, G. Thiel, A. Moroni
Structural determinant of the Ivabradine-induced block of pacemaker HCN channels
2023 A. Saponaro, A. Porro, J. Wissmann, A.S. Sharifzadeh, A. Chaves-Sanjuan, D. Difrancesco, K. Hamacher, G. Thiel, A. Moroni
Editorial: The key role of lipids in the regulation of ion channels
2022 A. Saponaro, M. Lolicato
Validation of the binding stoichiometry between HCN channels and their neuronal regulator TRIP8b by single molecule measurements
2022 A. Saponaro, F. Vallese, A. Porro, O.B. Clarke
Structural and functional approaches to studying cAMP regulation of HCN channels
2021 A. Saponaro, G. Thiel, A. Moroni
Gating movements and ion permeation in {HCN}4 pacemaker channels
2021 A.C. Saponaro, D. Bauer, M. Hunter Giese, P. Swuec, A. Porro, F. Gasparri, A. Sadat Sharifzadeh, A. CHAVES SANJUAN, L. Alberio, G. Parisi, G. Cerutti, O.B. Clarke, K. Hamacher, H.M. Colecraft, F. Mancia, W.A. Hendrickson, S.A. Siegelbaum, D. DI FRANCESCO, M. Bolognesi, G. Thiel, B. Santoro, A. Moroni
Detection of ligand binding to purified HCN channels using fluorescence-based size exclusion chromatography
2021 A. Saponaro, A.S. Sharifzadeh, A. Moroni
Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin
2020 V. Nardone, A. Chaves-Sanjuan, M. Lapi, C. Airoldi, A. Saponaro, S. Pasqualato, D. Dolfini, C. Camilloni, A. Bernardini, N. Gnesutta, R. Mantovani, M. Nardini
Understanding Docking Complexes of Macromolecules Using HADDOCK: The Synergy between Experimental Data and Computations
2020 A.C. Saponaro, V. Maione, A. Bonvin, F. Cantini
Rational design of a mutation to investigate the role of the brain protein TRIP8b in limiting the cAMP response of HCN channels in neurons
2020 A.C. Saponaro, A. Porro, A. Binda, I. Rivolta, M. Pisoni, C. Donadoni
Cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4
2020 A. Porro, G. Thiel, A. Moroni, A.C. Saponaro
A functional K+ channel from tetraselmis virus 1, a member of the mimiviridae
2020 K. Kukovetz, B. Hertel, C.R. Schvarcz, A. Saponaro, M. Manthey, U. Burk, T. Greiner, G.F. Steward, J.L. van Etten, A. Moroni, G. Thiel, O. Rauh
Developing Synthetic Peptides to Regulate Native HCN Channels
2019 A. Saponaro, F. Cantini, A. Porro, A. Bucchi, D. Difrancesco, V. Maione, M. Laskowski, P. Mesirca, M. Mangoni, G. Thiel, L. Banci, B. Santoro, A. Moroni
Chimeric HCN Channels for Studying cAMP-Induced Conformational Changes in the C-Linker
2019 B. Introini, A. Saponaro, A. Bonicci, O. Rauh, F. Cantini, L. Banci, G. Thiel, A. Moroni
Protein Adsorption at the Air-Water Interface by a Charge Sensing Interferometric Technique
2019 P. Brocca, A. Saponaro, B. Introini, V. Rondelli, M. Pannuzzo, D. Raciti, M. Corti, A. Raudino
The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels
2019 A. Porro, A. Saponaro, F. Gasparri, D. Bauer, C. Gross, M. Pisoni, G. Abbandonato, K. Hamacher, B. Santoro, G. Thiel, A. Moroni
Assigning Function to the D and E Helices of HCN CNBD
2018 A. Saponaro, A. Porro, C. Donadoni, B. Santoro, G. Thiel, A. Moroni
Isothermal Titration Calorimetry : A Biophysical Method to Characterize the Interaction between Label-free Biomolecules in Solution
2018 A.C. Saponaro
Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel
2018 C. Gross, A. Saponaro, B. Santoro, A. Moroni, G. Thiel, K. Hamacher
A light-gated potassium channel for sustained neuronal inhibition
2018 L. Alberio, A. Locarno, A. Saponaro, E. Romano, V. Bercier, S. Albadri, F. Simeoni, S. Moleri, S. Pelucchi, A. Porro, E. Marcello, N. Barsotti, K. Kukovetz, A.J. Boender, A. Contestabile, S. Luo, A. Moutal, Y. Ji, G. Romani, M. Beltrame, F. Del Bene, M. Di Luca, R. Khanna, H.M. Colecraft, M. Pasqualetti, G. Thiel, R. Tonini, A. Moroni