SCOLASTICO, CARLO
SCOLASTICO, CARLO
DIPARTIMENTO DI CHIMICA ORGANICA E INDUSTRIALE (attivo dal 01/11/1984 al 26/04/2012)
Synthesis of Gd and [68Ga] complexes in conjugation with a conformationally-optimized RGD sequence as potential MRI and PET tumour-imaging probes
2012 L. Manzoni, L. Belvisi, D. Arosio, M.P. Bartolomeo, A. Bianchi, C. Brioschi, F. Buonsanti, C. Cabella, C. Casagrande, M. Civera, M. De Matteo, L. Fugazza, L. Lattuada, F. Maisano, L. Miragoli, C. Neira, M. Pilkington-Miksa, C. Scolastico
Design, Synthesis and Biological Evaluation of Novel cRGD-Paclitaxel Conjugates for Integrin-Assisted Drug Delivery
2012 M. Pilkington-Miksa, D. Arosio, L. Battistini, L. Belvisi, M. De Matteo, F. Vasile, P. Burreddu, P. Carta, G. Rassu, P. Perego, N. Carenini, F. Zunino, M. De Cesare, V. Castiglioni, E. Scanziani, C. Scolastico, G. Casiraghi, F. Zanardi, L. Manzoni
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib
2010 D. Lecis, C. Drago, L. Manzoni, P. Seneci, C. Scolastico, E. Mastrangelo, M. Bolognesi, A. Anichini, H. Kashkar, H. Walczak, D. Delia
Recognition of Smac-mimetic compounds by the BIR domain of cIAP1
2010 F. Cossu, F. Malvezzi, G. Canevari, E. Mastrangelo, D. Lecis, D. Delia, P. Seneci, C. Scolastico, M. Bolognesi, M. Milani
Combination of Smac-mimetics and TNFalpha induce apoptosis in glioma cell lines
2010 C. Battaglia, M. Marizzoni, P. Seneci, C. Drago, C. Scolastico
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy
2009 P. Seneci, A. Bianchi, C. Battaglia, L. Belvisi, M. Bolognesi, A. Caprini, F. Cossu, E. Franco, M. DE MATTEO, D. Delia, C. Drago, A. Khaled, D. Lecis, L. Manzoni, M. Marizzoni, E. Mastrangelo, M. Milani, I. Motto, E. Moroni, D. Potenza, V. Rizzo, F. Servida, E. Turlizzi, M. Varrone, F. Vasile, C. Scolastico
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
2009 F. Cossu, E. Mastrangelo, M. Milani, G. Sorrentino, D. Lecis, D. Delia, L. Manzoni, P. Seneci, C. Scolastico, M. Bolognesi
Cyclic RGD-containing functionalized azabicycloalkane peptides as potent integrin antagonists for tumor targeting
2009 L. Manzoni, L. Belvisi, D. Arosio, M. Civera, M. Pilkington-Miksa, D. Potenza, A. Caprini, E.M.V. Araldi, E. Monferini, M. Mancino, F. Podestà, C. Scolastico
Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP Protein Family
2009 F. Cossu, M. Milani, E. Mastrangelo, P. Vachette, F. Servida, D. Lecis, G. Canevari, D. Delia, C. Drago, V. Rizzo, L. Manzoni, P. Seneci, C. Scolastico, M. Bolognesi
New SMAC mimetic compounds as apoptosis inducers
2009 C. Scolastico, L.P. Manzoni, P. Seneci, L. Belvisi, D. Delia, M. Bolognesi, E. Mastrangelo, M. De Mayo De Mari Milani, I.M. Motto, C. Drago
Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles
2008 E. Mastrangelo, F. Cossu, M. Milani, G. Sorrentino, D. Lecis, D. Delia, L. Manzoni, C. Drago, P. Seneci, C. Scolastico, V. Rizzo, M. Bolognesi
A Potent Integrin Antagonist from a Small Library of Cyclic RGD Pentapeptide Mimics Including Benzyl-Substituted Azabicycloalkane Amino Acids
2008 D. Arosio, L. Belvisi, L. Colombo, M. Colombo, D. Invernizzi, L. Manzoni, D. Potenza, M. Serra, M. Castorina, C. Pisano, C. Scolastico
Design of SMAC-Diablo Mimics Targeting XIAP/BIR3 Domain for Apoptosis Induction: a Computational Study.
2007 I. Motto, L. Belvisi, C. Drago, L. Manzoni, D. Potenza, C. Scolastico, P. Seneci
Nonpeptide Integrin Antagonists : RGD Mimetics Incorporating Substituted Azabicycloalkanes as Amino Acid Replacements
2007 L. Manzoni, M. Bassanini, L. Belvisi, I. Motto, C. Scolastico, M. Castorina, C. Pisano
Targeting integrins: Insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids
2006 L. Belvisi, A. Bernardi, M. Colombo, L. Manzoni, D. Potenza, C. Scolastico, G. Giannini, M. Marcellini, T. Riccioni, M. Castorina, P. Logiudice, C. Pisano
Synthesis of functionalized azabicycloalkane amino acids as dipeptide mimics
2006 L. MANZONI, L. BELVISI, E. DICARLO, A. FORNI, D. INVERNIZZI, C. SCOLASTICO
Click chemistry to functionalise peptidomimetics
2006 D. AROSIO, M. BERTOLI, L. MANZONI, C. SCOLASTICO
Biological and molecular properties of a new alpha(v)beta(3)/alpha(v)beta(5) integrin antagonist
2005 L. Belvisi, T. Riccioni, M. Marcellini, L. Vesci, I. Chiarucci, D. Efrati, D. Potenza, C. Scolastico, L. Manzoni, K. Lombardo, M.A. Stasi, A. Orlandi, A. Ciucci, B. Nico, D. Ribatti, G. Giannini, M. Presta, P. Carminati, C. Pisano
Functionalized azabicycloalkane amino acids by nitrone 1,3-dipolar intramolecular cycloaddition
2005 L. Manzoni, D. Arosio, L. Belvisi, A. Bracci, M. Colombo, D. Invernizzi, C. Scolastico
Design, synthesis, conformational analysis and application of azabicycloalkane amino acids as constrained dipeptide mimics
2004 L. Belvisi, L. Colombo, L. Manzoni, D. Potenza, C. Scolastico