Sharpless modified Huisgen's [2+3] cycloaddition of azide and acetylenic derivatives was employed as an efficient and simple method to conjugate azabicycloalkane amino acids, mimics of a homoSer-Pro dipeptide, with biologically relevant partners.
Click chemistry to functionalise peptidomimetics / D. AROSIO, M. BERTOLI, L. MANZONI, C. SCOLASTICO. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 47:22(2006), pp. 3697-3700.
Click chemistry to functionalise peptidomimetics
D. AROSIOPrimo
;C. SCOLASTICOUltimo
2006
Abstract
Sharpless modified Huisgen's [2+3] cycloaddition of azide and acetylenic derivatives was employed as an efficient and simple method to conjugate azabicycloalkane amino acids, mimics of a homoSer-Pro dipeptide, with biologically relevant partners.
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