BRUNETTI, DARIO
BRUNETTI, DARIO
Dipartimento di Scienze Cliniche e di Comunità
The mitochondrial unfolded protein response in human microglia disrupts neuronal–glial communication and promotes senescence
2026 M.J.P. J, A. Lam, C. Weissleder, F. Bertoli, H. Raji, M. Bosch, I. Nemazanyy, S. Kalb, M. Kehili, I. Hirschberg, D. Brunetti, I. Heckenbach, M. Scheibye-Knudsen, M. Deleidi
The SIRT1 activator SRT2104 exerts exercise mimetic effects and promotes Duchenne muscular dystrophy recovery
2025 M. Giovarelli, S. Zecchini, S.R. Casati, L. Lociuro, O. Gjana, L. Mollica, E. Pisanu, H.D. Mbissam, O. Cappellari, C. De Santis, A. Arcari, A. Bigot, G. Clerici, E. Catalani, S. Del Quondam, A. Andolfo, C. Braccia, M.G. Cattaneo, C. Banfi, D. Brunetti, E. Mocciaro, A. De Luca, E. Clementi, D. Cervia, C. Perrotta, C. De Palma
Transabdominal ultrasound guided AAV9-GFP delivery in fetal pigs: a translational and minimally invasive model for in utero fetal gene therapy
2025 A. Di Donfrancesco, A. Adelizzi, A. Giri, R. Duchi, S. Boito, M. Barandalla, G. Massaro, C. Santanatoglia, E. Cappellozza, A. Perota, I. Di Meo, V. Tiranti, E. Bottani, C. Galli, N. Persico, D. Brunetti
Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging
2025 G. Civiletto, D. Brunetti, G. Lizzo, K. Muller, G.E. Jacot, I. Daskalaki, F. Sizzano, M. Huh, I. Di Meo, M. Nicol Colombo, J.L. Sanchez-Garcia, B.J. Bétrisey, A. Zollinger, P. Lino, C. Neal, A. Egesipe, J. Richard, M. Chimen, A. Hermant, B. Brinon, L. Texari, S. Metairon, M. Adnan Qureshi, D.S. Patel, S.A. Vanapalli, M. Malavolta, A.W. Gao, A. Lalou, M. Provinciali, F. Orlando, V. Tiranti, R.T. Brooke, S. Horvath, J. Auwerx, J.N. Feige, P. Gut
SRT2104, a new SIRT1 activator, is an effective metabolic enhancer that promotes muscle recovery in DMD
2024 L. Lociuro, O. Gjana, S.R. Casati, S. Zecchini, M. Giovarelli, D. Brunetti, G. Clerici, M.G. Cattaneo, C. Banfi, L. Mollica, C. De Palma
Fetal and obstetrics manifestations of mitochondrial diseases
2024 A. Adelizzi, A. Giri, A. Di Donfrancesco, S. Boito, A. Prigione, E. Bottani, V. Bollati, V. Tiranti, N. Persico, D. Brunetti
SRT2104, a new SIRT1 activator, is an effective metabolic enhancer that promotes muscle recovery in DMD
2024 M. Giovarelli, S. Zecchini, S. Casati, G. Clerici, L. Mollica, M. Cattaneo, D. Brunetti, C. Banfi, C. Perrotta, C. DE PALMA
Comprehensive longitudinal non-invasive quantification of healthspan and frailty in a large cohort (n = 546) of geriatric C57BL/6 J mice
2023 S. Marcozzi, G. Bigossi, M.E. Giuliani, R. Giacconi, M. Cardelli, F. Piacenza, F. Orlando, A. Segala, A. Valerio, E. Nisoli, D. Brunetti, A. Puca, F. Boschi, C. Gaetano, A. Mongelli, F. Lattanzio, M. Provinciali, M. Malavolta
PPAR-gamma agonist pioglitazone recovers mitochondrial quality control in fibroblasts from PITRM1-deficient patients
2023 A. Di Donfrancesco, C. Berlingieri, M. Giacomello, C. Frascarelli, A.P. Magalhaes Rebelo, L.A. Bindoff, S. Reeval, P. Renbaum, F.M. Santorelli, G. Massaro, C. Viscomi, M. Zeviani, D. Ghezzi, E. Bottani, D. Brunetti
Generation of two human iPSC lines, HMGUi004-A and FINCBi004-A, from fibroblasts of MPAN patients carrying pathogenic recessive mutations in the gene C19orf12
2023 E. Zanuttigh, E. Rusha, C. Peron, D. Brunetti, G. Zorzi, A. Pertek, P. Nteli, J. Winkelmann, V. Tiranti, A. Iuso
Cellular senescence and frailty: a comprehensive insight into the causal links
2023 S. Marcozzi, G. Bigossi, M. Elisa Giuliani, R. Giacconi, F. Piacenza, M. Cardelli, D. Brunetti, A. Segala, A. Valerio, E. Nisoli, F. Lattanzio, M. Provinciali, M. Malavolta
SRT2104, a new SIRT1 activator, is an effective metabolic enhancer that promotes muscle recovery in DMD
2023 M. Giovarelli, S. Zecchini, S. Casati, G. Clerici, L. Mollica, M. Cattaneo, D. Brunetti, C. Banfi, C. Perrotta, C. DE PALMA
Advances in Mitochondria-Targeted Drug Delivery
2023 E. Bottani, D. Brunetti
Gene Therapy for Mitochondrial Diseases: Current Status and Future Perspective
2022 A. Di Donfrancesco, G. Massaro, I. DI MEO, V. Tiranti, E. Bottani, D. Brunetti
SRT2104, a new specific SIRT1 activator, promotes muscle recovery enhancing mitochondrial metabolism in DMD
2022 S. Zecchini, S. Casati, L. Mollica, M. Cattaneo, C. Banfi, D. Brunetti, C. Perrotta, E. Clementi, M. Giovarelli, C. De Palma
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome
2021 G. Inak, A. Rybak-Wolf, P. Lisowski, T.M. Pentimalli, R. Jüttner, P. Glažar, K. Uppal, E. Bottani, D. Brunetti, C. Secker, A. Zink, D. Meierhofer, M. Henke, M. Dey, U. Ciptasari, B. Mlody, T. Hahn, M. Berruezo-Llacuna, N. Karaiskos, M. Di Virgilio, J.A. Mayr, S.B. Wortmann, J. Priller, M. Gotthardt, D.P. Jones, E. Mayatepek, W. Stenzel, S. Diecke, R. Kühn, E.E. Wanker, N. Rajewsky, M. Schuelke, A. Prigione
Mitochondria in neurogenesis: Implications for mitochondrial diseases
2021 D. Brunetti, W. Dykstra, S. Le, A. Zink, A. Prigione
Role of PITRM1 in Mitochondrial Dysfunction and Neurodegeneration
2021 D. Brunetti, A. Catania, C. Viscomi, M. Deleidi, L.A. Bindoff, D. Ghezzi, M. Zeviani
Farmaci per il trattamento dell'obesità
2020 E. Bottani, D. Brunetti, E. Nisoli
Exploring the relevance of senotherapeutics for the current SARS-CoV-2 emergency and similar future global health threats
2020 M. Malavolta, R. Giacconi, D. Brunetti, M. Provinciali, F. Maggi