Glyphosate and glufosinate are broad spectrum herbicides, widely used in agriculture and in inhabited or industrialised areas, and aminomethylphosphonic acid is a degradation product of glyphosate. In 2015, the International Agency for Research on Cancer reported that glyphosate is a probable carcinogenic. In 2017, however, a scientific opinion of the European Chemicals Agency concluded that glyphosate is not proven to be carcinogenic, mutagenic or to have negative effects on reproduction. Nevertheless, aminomethylphosphonic acid was not considered. Due to their chemical-physical characteristics, these molecules present difficulties that have not yet allowed routine monitoring to be carried out. For these reasons, we developed and validated a simple and versatile liquid extraction, before IC-HRMS analysis, of three different complex matrices: honey, bass fish and bovine muscle. Among the satisfactory validation parameters, the LOQs in the range of 4.30-9.26 ng g-1 demonstrated high method sensitivity, compared to the few works present in literature. Finally, the method was applied to real commercial samples, which showed no traces of the selected pesticides.
Detection of glyphosate and its metabolites in food of animal origin based on ion-chromatography-high resolution mass spectrometry (IC-HRMS) / L.M. Chiesa, M. Nobile, S. Panseri, F. Arioli. - In: FOOD ADDITIVES & CONTAMINANTS. PART A. CHEMISTRY, ANALYSIS, CONTROL, EXPOSURE & RISK ASSESSMENT. - ISSN 1944-0049. - 36:4(2019), pp. 592-600.
|Titolo:||Detection of glyphosate and its metabolites in food of animal origin based on ion-chromatography-high resolution mass spectrometry (IC-HRMS)|
CHIESA, LUCA MARIA (Co-primo)
NOBILE, MARIA (Co-primo)
PANSERI, SARA (Corresponding)
ARIOLI, FRANCESCO (Ultimo)
|Parole Chiave:||Honey; fish; meat; glyphosate; AMPA; glufosinate; food safety|
|Settore Scientifico Disciplinare:||Settore VET/04 - Ispezione degli Alimenti di Origine Animale|
Settore VET/07 - Farmacologia e Tossicologia Veterinaria
|Data di pubblicazione:||2019|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1080/19440049.2019.1583380|
|Appare nelle tipologie:||01 - Articolo su periodico|
File in questo prodotto:
|110glyphosate and its metabolites in food of AO 2019.pdf||Publisher's version/PDF||Administrator Richiedi una copia|