MANFRINI, NICOLA
MANFRINI, NICOLA
Dipartimento di Bioscienze
SARS-CoV-2: A Glance at the Innate Immune Response Elicited by Infection and Vaccination
2024 N. Manfrini, S. Notarbartolo, R. Grifantini, E. Pesce
FAM46C Is an Interferon-Stimulated Gene That Inhibits Lentiviral Particle Production by Modulating Autophagy
2023 M. Mancino, G. Lai, F. De Grossi, A. Cuomo, L. Manganaro, G.M. Butta, I. Ferrari, E. Vicenzi, G. Poli, E. Pesce, S. Oliveto, S. Biffo, N. Manfrini
Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2
2023 A. Miluzio, A. Cuomo, C. Cordiglieri, L. Donnici, E. Pesce, M. Bombaci, M. Conti, A. Fasciani, L. Terracciano, L. Manganaro, M. Toccafondi, A. Scagliola, S. Oliveto, S. Ricciardi, R. Grifantini, R. DE FRANCESCO, S. Abrignani, N. Manfrini, S. Biffo
RACK1 release from the Ribosome Couples Translational Regulation with Starving Signaling and Possibly Depends on Phosphorylation of Key Serine and Threonine Residues
2023 M. Kiratzis, G. Lai, P. Calamita, M. Mancino, M. Iriti, N. Manfrini, S. Gallo
Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response
2022 E. Pesce, N. Manfrini, C. Cordiglieri, S. Santi, A. Bandera, A. Gobbini, P. Gruarin, A. Favalli, M. Bombaci, A. Cuomo, F. Collino, G. Cricrì, R. Ungaro, A. Lombardi, D. Mangioni, A. Muscatello, S. Aliberti, F. Blasi, A. Gori, S. Abrignani, R. De Francesco, S. Biffo, R. Grifantini
Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study
2022 A. Scagliola, A. Miluzio, G. Mori, S. Ricciardi, S. Oliveto, N. Manfrini, S. Biffo
Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma
2021 A. Scagliola, A. Miluzio, G. Ventura, S. Oliveto, C. Cordiglieri, N. Manfrini, D. Cirino, S. Ricciardi, L. Valenti, G. Baselli, R. D'Ambrosio, M. Maggioni, D. Brina, A. Bresciani, S. Biffo
Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma
2021 A. Scagliola, A. Miluzio, G. Ventura, S. Oliveto, C. Cordiglieri, N. Manfrini, D. Cirino, S. Ricciardi, L. Valenti, G. Baselli, R. D'Ambrosio, M. Maggioni, D. Brina, A. Bresciani, S. Biffo
Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis
2021 A. Ajazi, C. Bruhn, G. Shubassi, C. Lucca, E. Ferrari, A. Cattaneo, A. Bachi, N. Manfrini, S. Biffo, E. Martini, S. Minucci, C. Vernieri, M. Foiani
Ribosome profiling unveils translational regulation of metabolic enzymes in primary CD4+ Th1 cells
2020 N. Manfrini, S. Ricciardi, R. Alfieri, G. Ventura, P. Calamita, A. Favalli, S. Biffo
FAM46C and FNDC3A are multiple myeloma tumor suppressors that act in concert to impair clearing of protein aggregates and autophagy
2020 N. Manfrini, M. Mancino, A. Miluzio, S. Oliveto, M. Balestra, P. Calamita, R. Alfieri, R.L. Rossi, M. Sassoè-Pognetto, C. Salio, A. Cuomo, T. Bonaldi, M. Manfredi, E. Marengo, E. Ranzato, S. Martinotti, D. Cittaro, G. Tonon, S. Biffo
Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits
2020 E. Pesce, A. Miluzio, L. Turcano, C. Minici, D. Cirino, P. Calamita, N. Manfrini, S. Oliveto, S. Ricciardi, R. Grifantini, M. Degano, A. Bresciani, S. Biffo
Ribosomal RACK1 promotes proliferation of neuroblastoma cells independently of global translation upregulation
2019 N. Romano, M. Veronese, N. Manfrini, L. Zolla, M. Ceci
Rack1 specifically regulates translation through its binding to ribosomes
2018 S. Gallo, S. Ricciardi, N. Manfrini, S. Oliveto, P. Calamita, M. Mancino, E. Maffioli, M. Moro, M. Crosti, V. Berno, M. Bombaci, G. Tedeschi, E. Pesce, S. Biffo
Crosstalks between translation and metabolism in cancer
2018 S. Biffo, N. Manfrini, S. Ricciardi
The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling
2018 S. Ricciardi, N. Manfrini, R. Alfieri, P. Calamita, M.C. Crosti, G. Simone, R. Müller, M. Pagani, S. Abrignani, S. Biffo
Role of microRNAs in translation regulation and cancer
2017 S. Oliveto, M. Mancino, N. Manfrini, S. Biffo
Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation
2017 N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M.H. de Angelis, S. Biffo
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+T cells in both mice and humans
2017 N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, D. Brina, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M. Hrabě de Angelis, S. Biffo
Translational control by mTOR-independent routes: How eIF6 organizes metabolism
2016 A. Miluzio, S. Ricciardi, N. Manfrini, R. Alfieri, S. Oliveto, D. Brina, S. Biffo