MANFRINI, NICOLA
MANFRINI, NICOLA
Dipartimento di Bioscienze
Crosstalks between translation and metabolism in cancer
2018 S. Biffo, N. Manfrini, S. Ricciardi
Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation
2017 N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M.H. de Angelis, S. Biffo
Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits
2020 E. Pesce, A. Miluzio, L. Turcano, C. Minici, D. Cirino, P. Calamita, N. Manfrini, S. Oliveto, S. Ricciardi, R. Grifantini, M. Degano, A. Bresciani, S. Biffo
DNA double-strand breaks in meiosis : Checking their formation, processing and repair
2009 M.P. Longhese, D. Bonetti, I. Guerini, N. Manfrini, M. Clerici
Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis
2021 A. Ajazi, C. Bruhn, G. Shubassi, C. Lucca, E. Ferrari, A. Cattaneo, A. Bachi, N. Manfrini, S. Biffo, E. Martini, S. Minucci, C. Vernieri, M. Foiani
Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response
2022 E. Pesce, N. Manfrini, C. Cordiglieri, S. Santi, A. Bandera, A. Gobbini, P. Gruarin, A. Favalli, M. Bombaci, A. Cuomo, F. Collino, G. Cricrì, R. Ungaro, A. Lombardi, D. Mangioni, A. Muscatello, S. Aliberti, F. Blasi, A. Gori, S. Abrignani, R. De Francesco, S. Biffo, R. Grifantini
FAM46C and FNDC3A are multiple myeloma tumor suppressors that act in concert to impair clearing of protein aggregates and autophagy
2020 N. Manfrini, M. Mancino, A. Miluzio, S. Oliveto, M. Balestra, P. Calamita, R. Alfieri, R.L. Rossi, M. Sassoè-Pognetto, C. Salio, A. Cuomo, T. Bonaldi, M. Manfredi, E. Marengo, E. Ranzato, S. Martinotti, D. Cittaro, G. Tonon, S. Biffo
G1/S and G2/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint
2012 N. Manfrini, E. Gobbini, V. Baldo, C. Trovesi, G. Lucchini, M.P. Longhese
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+T cells in both mice and humans
2017 N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, D. Brina, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M. Hrabě de Angelis, S. Biffo
Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study
2022 A. Scagliola, A. Miluzio, G. Mori, S. Ricciardi, S. Oliveto, N. Manfrini, S. Biffo
Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2
2023 A. Miluzio, A. Cuomo, C. Cordiglieri, L. Donnici, E. Pesce, M. Bombaci, M. Conti, A. Fasciani, L. Terracciano, L. Manganaro, M. Toccafondi, A. Scagliola, S. Oliveto, S. Ricciardi, R. Grifantini, R. DE FRANCESCO, S. Abrignani, N. Manfrini, S. Biffo
Mechanisms and regulation of DNA end resection
2010 M.P. Longhese, D. Bonetti, N. Manfrini, M. Clerici
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases
2010 N. Manfrini, I. Guerini, A. Citterio, G. Lucchini, M.P. Longhese
Rack1 specifically regulates translation through its binding to ribosomes
2018 S. Gallo, S. Ricciardi, N. Manfrini, S. Oliveto, P. Calamita, M. Mancino, E. Maffioli, M. Moro, M. Crosti, V. Berno, M. Bombaci, G. Tedeschi, E. Pesce, S. Biffo
Regulation of the DNA damage response by cyclin-dependent kinases
2013 C. Trovesi, N. Manfrini, M. Falcettoni, M.P. Longhese
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae
2015 N. Manfrini, M. Clerici, M. Wery, C.V. Colombo, M. Descrimes, A. Morillon, F. d'Adda di fagagna, M.P. Longhese
Ribosomal RACK1 promotes proliferation of neuroblastoma cells independently of global translation upregulation
2019 N. Romano, M. Veronese, N. Manfrini, L. Zolla, M. Ceci
Ribosome profiling unveils translational regulation of metabolic enzymes in primary CD4+ Th1 cells
2020 N. Manfrini, S. Ricciardi, R. Alfieri, G. Ventura, P. Calamita, A. Favalli, S. Biffo
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA
2015 N. Manfrini, C. Trovesi, M. Wery, M. Martina, D. Cesena, M. Descrimes, A. Morillon, F. D'Adda Di Fagagna, M.P. Longhese
Role of microRNAs in translation regulation and cancer
2017 S. Oliveto, M. Mancino, N. Manfrini, S. Biffo