MANFRINI, NICOLA
MANFRINI, NICOLA
Dipartimento di Bioscienze
Modulation of Autophagy by Oncosuppressor FAM46C and Its Implications for Cancer Therapy: An Intriguing Perspective
2025 N. Manfrini
CancerHubs: a systematic data mining and elaboration approach for identifying novel cancer-related protein interaction hubs
2025 I. Ferrari, F. De Grossi, G. Lai, S. Oliveto, G. Deroma, S. Biffo, N. Manfrini
The power of microRNA regulation-insights into immunity and metabolism
2025 S. Oliveto, N. Manfrini, S. Biffo
SARS-CoV-2: A Glance at the Innate Immune Response Elicited by Infection and Vaccination
2024 N. Manfrini, S. Notarbartolo, R. Grifantini, E. Pesce
Dissecting the Puzzling Roles of FAM46C: A Multifaceted Pan-Cancer Tumour Suppressor with Increasing Clinical Relevance
2024 G. Lai, F. DE GROSSI, I. Catusi, E. Pesce, N. Manfrini
FAM46C Is an Interferon-Stimulated Gene That Inhibits Lentiviral Particle Production by Modulating Autophagy
2023 M. Mancino, G. Lai, F. De Grossi, A. Cuomo, L. Manganaro, G.M. Butta, I. Ferrari, E. Vicenzi, G. Poli, E. Pesce, S. Oliveto, S. Biffo, N. Manfrini
Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2
2023 A. Miluzio, A. Cuomo, C. Cordiglieri, L. Donnici, E. Pesce, M. Bombaci, M. Conti, A. Fasciani, L. Terracciano, L. Manganaro, M. Toccafondi, A. Scagliola, S. Oliveto, S. Ricciardi, R. Grifantini, R. DE FRANCESCO, S. Abrignani, N. Manfrini, S. Biffo
RACK1 release from the Ribosome Couples Translational Regulation with Starving Signaling and Possibly Depends on Phosphorylation of Key Serine and Threonine Residues
2023 M. Kiratzis, G. Lai, P. Calamita, M. Mancino, M. Iriti, N. Manfrini, S. Gallo
Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response
2022 E. Pesce, N. Manfrini, C. Cordiglieri, S. Santi, A. Bandera, A. Gobbini, P. Gruarin, A. Favalli, M. Bombaci, A. Cuomo, F. Collino, G. Cricrì, R. Ungaro, A. Lombardi, D. Mangioni, A. Muscatello, S. Aliberti, F. Blasi, A. Gori, S. Abrignani, R. De Francesco, S. Biffo, R. Grifantini
Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study
2022 A. Scagliola, A. Miluzio, G. Mori, S. Ricciardi, S. Oliveto, N. Manfrini, S. Biffo
Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis
2021 A. Ajazi, C. Bruhn, G. Shubassi, C. Lucca, E. Ferrari, A. Cattaneo, A. Bachi, N. Manfrini, S. Biffo, E. Martini, S. Minucci, C. Vernieri, M. Foiani
Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma
2021 A. Scagliola, A. Miluzio, G. Ventura, S. Oliveto, C. Cordiglieri, N. Manfrini, D. Cirino, S. Ricciardi, L. Valenti, G. Baselli, R. D'Ambrosio, M. Maggioni, D. Brina, A. Bresciani, S. Biffo
Ribosome profiling unveils translational regulation of metabolic enzymes in primary CD4+ Th1 cells
2020 N. Manfrini, S. Ricciardi, R. Alfieri, G. Ventura, P. Calamita, A. Favalli, S. Biffo
Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits
2020 E. Pesce, A. Miluzio, L. Turcano, C. Minici, D. Cirino, P. Calamita, N. Manfrini, S. Oliveto, S. Ricciardi, R. Grifantini, M. Degano, A. Bresciani, S. Biffo
FAM46C and FNDC3A are multiple myeloma tumor suppressors that act in concert to impair clearing of protein aggregates and autophagy
2020 N. Manfrini, M. Mancino, A. Miluzio, S. Oliveto, M. Balestra, P. Calamita, R. Alfieri, R.L. Rossi, M. Sassoè-Pognetto, C. Salio, A. Cuomo, T. Bonaldi, M. Manfredi, E. Marengo, E. Ranzato, S. Martinotti, D. Cittaro, G. Tonon, S. Biffo
Ribosomal RACK1 promotes proliferation of neuroblastoma cells independently of global translation upregulation
2019 N. Romano, M. Veronese, N. Manfrini, L. Zolla, M. Ceci
Rack1 specifically regulates translation through its binding to ribosomes
2018 S. Gallo, S. Ricciardi, N. Manfrini, S. Oliveto, P. Calamita, M. Mancino, E. Maffioli, M. Moro, M. Crosti, V. Berno, M. Bombaci, G. Tedeschi, E. Pesce, S. Biffo
Crosstalks between translation and metabolism in cancer
2018 S. Biffo, N. Manfrini, S. Ricciardi
The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling
2018 S. Ricciardi, N. Manfrini, R. Alfieri, P. Calamita, M.C. Crosti, G. Simone, R. Müller, M. Pagani, S. Abrignani, S. Biffo
Role of microRNAs in translation regulation and cancer
2017 S. Oliveto, M. Mancino, N. Manfrini, S. Biffo