MILUZIO, ANNARITA
MILUZIO, ANNARITA
Universita' degli Studi di MILANO
Exploiting the Potential of Computational Approaches in Medicinal Chemistry: CADD of Novel eIF6 Binders for the Development of anti-HCC PROTACs
2025 A. Colleoni, E.M.A. Fassi, A. Miluzio, G. Tempra, M. Albani, M. DE AMICI, G. Grazioso, S. Biffo, C. Matera
The Impact of 3D Nichoids and Matrix Stiffness on Primary Malignant Mesothelioma Cells
2024 S. Oliveto, P. Ritter, G. Deroma, A. Miluzio, C. Cordiglieri, M.R. Benvenuti, L. Mutti, M.T. Raimondi, S. Biffo
Targeted degraders of eIF6: a novel strategy to remodulate liver pathological lipidic metabolism
2024 A. Colleoni, E.M.A. Fassi, A. Miluzio, M. Albani, D. Lecchi, G. Tempra, M. DE AMICI, G. Grazioso, S. Biffo, C. Matera
Tackling Hepatocellular Carcinoma with Targeted Degraders of eIF6
2024 A. Colleoni, E.M.A. Fassi, A. Miluzio, M. Albani, D. Lecchi, M. De Amici, G. Grazioso, S. Biffo, C. Matera
Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study
2022 A. Scagliola, A. Miluzio, G. Mori, S. Ricciardi, S. Oliveto, N. Manfrini, S. Biffo
Assessment of Sacsin Turnover in Patients With ARSACS: Implications for Molecular Diagnosis and Pathogenesis
2021 F. Longo, D. De Ritis, A. Miluzio, D. Fraticelli, J. Baets, M. Scarlato, F.M. Santorelli, S. Biffo, F. Maltecca
Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma
2021 A. Scagliola, A. Miluzio, G. Ventura, S. Oliveto, C. Cordiglieri, N. Manfrini, D. Cirino, S. Ricciardi, L. Valenti, G. Baselli, R. D'Ambrosio, M. Maggioni, D. Brina, A. Bresciani, S. Biffo
Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits
2020 E. Pesce, A. Miluzio, L. Turcano, C. Minici, D. Cirino, P. Calamita, N. Manfrini, S. Oliveto, S. Ricciardi, R. Grifantini, M. Degano, A. Bresciani, S. Biffo
FAM46C and FNDC3A are multiple myeloma tumor suppressors that act in concert to impair clearing of protein aggregates and autophagy
2020 N. Manfrini, M. Mancino, A. Miluzio, S. Oliveto, M. Balestra, P. Calamita, R. Alfieri, R.L. Rossi, M. Sassoè-Pognetto, C. Salio, A. Cuomo, T. Bonaldi, M. Manfredi, E. Marengo, E. Ranzato, S. Martinotti, D. Cittaro, G. Tonon, S. Biffo
Translating the Game: Ribosomes as Active Players
2018 P. Calamita, G. Gatti, A. Miluzio, A. Scagliola, S. Biffo
MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state
2018 V. Poli, L. Fagnocchi, A. Fasciani, A. Cherubini, S. Mazzoleni, S. Ferrillo, A. Miluzio, G. Gaudioso, V. Vaira, A. Turdo, M. Gaggianesi, A. Chinnici, E. Lipari, S. Bicciato, S. Bosari, M. Todaro, A. Zippo
A polysome-based microRNA screen identifies miR-24-3p as a novel pro-migratory miRNA in mesothelioma
2018 S. Oliveto, R. Alfieri, A. Miluzio, A. Scagliola, R.S. Seclì, P. Gasparini, S. Grosso, L. Cascione, L. Mutti, S. Biffo
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+T cells in both mice and humans
2017 N. Manfrini, S. Ricciardi, A. Miluzio, M. Fedeli, A. Scagliola, S. Gallo, D. Brina, T. Adler, D.H. Busch, V. Gailus-Durner, H. Fuchs, M. Hrabě de Angelis, S. Biffo
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention
2017 P. Calamita, A. Miluzio, A. Russo, E. Pesce, S. Ricciardi, F. Khanim, C. Cheroni, R. Alfieri, M. Mancino, C. Gorrini, G. Rossetti, I. Peluso, M. Pagani, D.L. Medina, J. Rommens, S. Biffo
Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation
2015 S. Ricciardi, A. Miluzio, D. Brina, K. Clarke, M. Bonomo, R. Aiolfi, L.G. Guidotti, F. Falciani, S. Biffo
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription
2015 D. Brina, A. Miluzio, S. Ricciardi, K. Clarke, P.K. Davidsen, G. Viero, T. Tebaldi, N. Offenhäuser, J. Rozman, B. Rathkolb, S. Neschen, M. Klingenspor, E. Wolf, V. Gailus-Durner, H. Fuchs, M. Hrabe De Angelis, A. Quattrone, F. Falciani, S. Biffo
Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo
2015 A. Miluzio, S. Oliveto, E. Pesce, L. Mutti, B. Murer, S. Grosso, S. Ricciardi, D. Brina, S. Biffo
Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation
2008 V. Gandin, A. Miluzio, A.M. Barbieri, A. Beugnet, H. Kiyokawa, P.C. Marchisio, S. Biffo
Nuclear Myosin VI Enhances RNA Polymerase II-Dependent Transcription
2006 S. Vreugde, C. Ferrai, A. Miluzio, E. Hauben, P.C. Marchisio, M.P. Crippa, M. Bussi, S. Biffo