CASIRAGHI, ANDREA
CASIRAGHI, ANDREA
Dipartimento di Scienze Farmaceutiche
Structural analogues of methylphenidate as Parkinson's disease-modifying agents
2022 A. Bellucci, F. Longhena, V. Straniero, A. Casiraghi, E. Valoti
Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson’s Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice
2022 A. Casiraghi, F. Longhena, G. Faustini, G. Ribaudo, L. Suigo, G. Andrea Camacho-Hernandez, F. Bono, V. Brembati, A. Hauck Newman, A. Gianoncelli, V. Straniero, A. Bellucci, E. Valoti
RnpA inhibitors as potential antimicrobials to fight antibiotic-resistance: Computational design, synthesis, and biological evaluation
2021 L. Suigo, M. Chojnacki, C. Zanotto, V. Sebastián-Pérez, C. De Giuli Morghen, A. Casiraghi, P. Dunman, E. Valoti, V. Straniero
Illuminating the norepinephrine transporter: fluorescent probes based on nisoxetine and talopram
2021 G.A. Camacho-Hernandez, A. Casiraghi, D. Rudin, D. Luethi, T.C. Ku, D.A. Guthrie, V. Straniero, E. Valoti, G.J. Schutz, H.H. Sitte, A.H. Newman
Staphylococcus aureus RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation
2021 L. Suigo, M. Chojnacki, C. Zanotto, V. Sebastián-Pérez, C. DE GIULI MORGHEN, A. Casiraghi, P.M. Dunman, E. Valoti, V. Straniero
Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket
2021 V. Straniero, V. Sebastián-Pérez, L. Suigo, W. Margolin, A. Casiraghi, M. Hrast, C. Zanotto, I. Zdovc, A. Radaelli, E. Valoti
PARKINSON'S DISEASE: VALIDATION OF A NOVEL TARGET THROUGH THE DEVELOPMENT OF METHYLPHENIDATE ANALOGS AS POTENTIAL MODULATOR AND FLUORESCENT PROBES
2020 A. Casiraghi
Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate
2020 G. Faustini, F. Longhena, A. Bruno, F. Bono, J. Grigoletto, L. La Via, A. Barbon, A. Casiraghi, V. Straniero, E. Valoti, G. Costantino, F. Benfenati, C. Missale, M. Pizzi, M.G. Spillantini, A. Bellucci
Targeting bacterial cell division: A binding site-centered approach to the most promising inhibitors of the essential protein FtsZ
2020 A. Casiraghi, L. Suigo, E. Valoti, V. Straniero
Design and synthesis of fluorescent-methylphenidate analogues for FRET-based assay of Synapsin III binding
2020 A. Casiraghi, F. Longhena, V. Straniero, G. Faustini, A.H. Newman, A. Bellucci, E. Valoti
Study of isosteric substitution of the 1,4-benzodioxane oxygen atoms in benzamides FtsZ inhibitors
2019 L. Suigo, V. Straniero, A. Casiraghi, E. Valoti
Benzodioxane‐Benzamides as Antibacterial Agents : Computational and SAR Studies to Evaluate the Influence of the 7‐Substitution in FtsZ Interaction
2019 V. Straniero, V. Sebastián‐Pérez, M. Hrast, C. Zanotto, A. Casiraghi, L. Suigo, I. Zdovc, A. Radaelli, C. De Giuli Morghen, E. Valoti
Novel modulators of α-Synuclein / Synapsin-III interaction as potential antiparkinsonian agents
2018 A. Casiraghi, V. Straniero, A. Bellucci, A. Bruno, F. Longhena, F. Bono, G. Costantino, E. Valoti
Synthesis and structure-activity relationship of novel inhibitors of the prokaryotic divisome protein FtsZ
2018 A. Casiraghi, V. Straniero, E. Valoti
How to fight antimicrobial resistance: design and synthesis of FTSZ inhibitors as novel potent gram-positive antibiotics
2018 V. Straniero, A. Casiraghi, E. Valoti
How do reaction conditions affect the enantiopure synthesis of 2-substituted-1,4-benzodioxane derivatives?
2018 V. Straniero, A. Casiraghi, L. Fumagalli, E. Valoti
How reaction conditions may influence the regioselectivity in the synthesis of 2,3-dihydro-1,4-benzoxathiine derivatives
2018 A. Casiraghi, E. Valoti, L. Suigo, A. Artasensi, E. Sorvillo, V. Straniero
Battle against antimicrobial resistance: FtsZ inhibitors as novel potent Gram-positive antibiotics
2017 V. Straniero, A. Casiraghi, E. Valoti
Solvent and substrate dependent regioselective synthesis of 2 and 3 substituted 2,3-dihydro-1,4-benzoxathiine
2017 V. Straniero, A. Casiraghi, E. Valoti
Solvent- and substrate-dependent regioselective synthesis of 2- and 3-substituted 2,3-dehydro-1,4-benzooxathiine
2017 V. Straniero, A. Casiraghi, E. Valoti