The present invention describes compounds of formula (A) for use as Parkinson's disease modifying agents, said formula (A). Surprisingly it has been found that the compounds of the invention can significantly reduce alpha-synuclein aggregation and stimulate the functional interaction between alpha-synuclein and Synapsin III.
Structural analogues of methylphenidate as Parkinson's disease-modifying agents / A. Bellucci, F. Longhena, V. Straniero, A. Casiraghi, E. Valoti.
Structural analogues of methylphenidate as Parkinson's disease-modifying agents
V. Straniero;A. Casiraghi;E. Valoti
2022
Abstract
The present invention describes compounds of formula (A) for use as Parkinson's disease modifying agents, said formula (A). Surprisingly it has been found that the compounds of the invention can significantly reduce alpha-synuclein aggregation and stimulate the functional interaction between alpha-synuclein and Synapsin III.
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