SUIGO, LORENZO
SUIGO, LORENZO
Dipartimento di Scienze Farmaceutiche
Targeting Bacterial Cell Division with Benzodioxane–Benzamide FtsZ Inhibitors as a Novel Strategy to Fight Gram-Positive Ovococcal Pathogens
2025 B. Furlan, M. Sobrinos-Sanguino, M. Sammartino, B. Monterroso, S. Zorrilla, A. Lanzini, L. Suigo, E. Valoti, O. Massidda, V. Straniero
Benzodioxane–Benzamides as FtsZ Inhibitors: Effects of Linker’s Functionalization on Gram-Positive Antimicrobial Activity
2023 L. Suigo, W. Margolin, E. Ulzurrun, M. Hrast Rambaher, C. Zanotto, V. Sebastián-Pérez, N.E. Campillo, V. Straniero, E. Valoti
PET Imaging of Innate Immune Activation Using 11C Radiotracers Targeting GPR84
2023 M. Kalita, J.H. Park, R.C. Kuo, S. Hayee, S. Marsango, V. Straniero, I.S. Alam, A. Rivera-Rodriguez, M. Pandrala, M.L. Carlson, S.T. Reyes, I.M. Jackson, L. Suigo, A. Luo, S.C. Nagy, E. Valoti, G. Milligan, F. Habte, B. Shen, M.L. James
DEVELOPMENT OF SMALL MOLECULES AS INHIBITORS OF FTSZ AND RNPA ACTING AS POTENTIAL ANTIMICROBIAL AGENTS
2023 L. Suigo
Benzodioxane-benzamides as promising inhibitors of Escherichia coli FtsZ
2023 L. Suigo, B. Monterroso, M. Sobrinos-Sanguino, C. Alfonso, V. Straniero, G. Rivas, S. Zorrilla, E. Valoti, W. Margolin
2-(1-Methoxycarbonyl-2-phenyleth-1-yl)-1-benzylpyridin-1-ium Bromide
2023 L. Suigo, V. Straniero, E. Valoti
Obtainment of Threo and Erythro Isomers of the 6-Fluoro-3-(2,3,6,7,8,9-hexahydronaphtho[2,3-b][1,4]dioxin-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide
2023 V. Straniero, L. Suigo, G. Lodigiani, E. Valoti
RESOLUTION VIA DIASTEREOMERIC AMIDES OF ENANTIOPURE 1,4-BENZOXATHIAN-2- AND 3-CARBOXYLIC ACIDS AND DETERMINATION OF THEIR CONFIGURATION
2022 G. Lodigiani, V. Straniero, L. Suigo, E. Valoti
Development of a reliable synthetic scheme to isolate 2-hydroxy-2-benzodioxanylethoxy benzamides for the obtainment of fluorescent probles
2022 L. Suigo, V. Straniero, E. Valoti
Design, synthesis and antimicrobial evaluation of benzodioxane-benzamides FtsZ inhibitors: modification of the linker between the two scaffolds
2022 L. Suigo, V. Straniero, G. Lodigiani, C. Zanotto, M. Sobrinos-Sanguino, B. Monterroso, S. Zorrilla, G. Rivas, E. Valoti
RnpA inhibitors as potential antistaphylococcal agents: computational design, synthesis, and biological evaluation
2022 L. Suigo, M. Chojnacki, C. Zanotto, V. Sebastián-Pérez, G. Lodigiani, P. Dunman, E. Valoti, V. Straniero
Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson’s Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice
2022 A. Casiraghi, F. Longhena, G. Faustini, G. Ribaudo, L. Suigo, G. Andrea Camacho-Hernandez, F. Bono, V. Brembati, A. Hauck Newman, A. Gianoncelli, V. Straniero, A. Bellucci, E. Valoti
(3-Methylene-2,3-dihydronaphtho[2,3-b][1,4]dioxin-2-yl)methanol
2022 L. Suigo, G. Lodigiani, V. Straniero, E. Valoti
Resolution via diastereomeric amides of enantiopure 1,4-benzoxathian-2- and 3-carboxylic acids and determination of their configuration
2022 V. Straniero, G. Lodigiani, L. Suigo, E. Valoti
RnpA inhibitors as potential antimicrobials to fight antibiotic-resistance: Computational design, synthesis, and biological evaluation
2021 L. Suigo, M. Chojnacki, C. Zanotto, V. Sebastián-Pérez, C. De Giuli Morghen, A. Casiraghi, P. Dunman, E. Valoti, V. Straniero
Benzodioxane-benzamide FtsZ inhibitors: Synthesis of new derivatives and their biophysical and biochemical evaluation
2021 L. Suigo, M. Sobrinos-Sanguino, S. Zorilla, B. Monterroso, C. Alfonso, G. Rivas, V. Straniero, E. Valoti
Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket
2021 V. Straniero, V. Sebastián-Pérez, L. Suigo, W. Margolin, A. Casiraghi, M. Hrast, C. Zanotto, I. Zdovc, A. Radaelli, E. Valoti
Staphylococcus aureus RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation
2021 L. Suigo, M. Chojnacki, C. Zanotto, V. Sebastián-Pérez, C. DE GIULI MORGHEN, A. Casiraghi, P.M. Dunman, E. Valoti, V. Straniero
Targeting bacterial cell division: A binding site-centered approach to the most promising inhibitors of the essential protein FtsZ
2020 A. Casiraghi, L. Suigo, E. Valoti, V. Straniero
Study of isosteric substitution of the 1,4-benzodioxane oxygen atoms in benzamides FtsZ inhibitors
2019 L. Suigo, V. Straniero, A. Casiraghi, E. Valoti