MANZO, STEFANO GIUSTINO
MANZO, STEFANO GIUSTINO
Dipartimento di Bioscienze
Coordinated control of genome-nuclear lamina interactions by topoisomerase 2B and lamin B receptor
2025 T. Van Schaik, M. Magnitov, M. De Haas, J. Breda, E. De Wit, A.G. Manjon, R.H. Medema, H.J. Gothe, V. Roukos, A.J. Buckle, C. Naughton, N. Gilbert, B. Van Steensel, S.G. Manzo
Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing
2024 R. Schep, M. Trauernicht, X. Vergara, A. Friskes, B. Morris, S. Gregoricchio, S.G. Manzo, W. Zwart, R.L. Beijersbergen, R.H. Medema, B. Van Steensel
Chromatin protein complexes involved in gene repression in lamina-associated domains
2024 S.G. Manzo, A. Mazouzi, C. Leemans, T. Van Schaik, N. Neyazi, M.S. Van Ruiten, B.D. Rowland, T.R. Brummelkamp, B. Van Steensel
Acute multi-level response to defective de novo chromatin assembly in S-phase
2024 J. Dreyer, G. Ricci, J. Van Den Berg, V. Bhardwaj, J. Funk, C. Armstrong, V. Van Batenburg, C. Sine, M.A. Vaninsberghe, R.B. Tjeerdsma, R. Marsman, I.K. Mandemaker, S. Di Sanzo, J. Costantini, S.G. Manzo, A. Biran, C. Burny, M.A.T.M. Van Vugt, M. Völker-Albert, A. Groth, S.L. Spencer, A. Van Oudenaarden, F. Mattiroli
Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements
2023 M. Trauernicht, C. Rastogi, S.G. Manzo, H.J. Bussemaker, B. van Steensel
Perturbations in 3D genome organization can promote acquired drug resistance
2023 A.G. Manjón, S.G. Manzo, S. Prekovic, L. Potgeter, T. van Schaik, N.Q. Liu, K. Flach, D. Peric-Hupkes, S. Joosten, H. Teunissen, A. Friskes, M. Ilic, D. Hintzen, V.H. Franceschini-Santos, W. Zwart, E. de Wit, B. van Steensel, R.H. Medema
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki-67
2022 T. van Schaik, S.G. Manzo, A.E. Vouzas, N.Q. Liu, H. Teunissen, E. de Wit, D.M. Gilbert, B. van Steensel
CTCF and cohesin promote focal detachment of DNA from the nuclear lamina
2022 T. van Schaik, N.Q. Liu, S.G. Manzo, D. Peric-Hupkes, E. de Wit, B. van Steensel
Genome-Wide Mapping and Microscopy Visualization of Protein-DNA Interactions by pA-DamID
2022 T. van Schaik, S.G. Manzo, B. van Steensel
Lamina-associated domains: Tethers and looseners
2022 S.G. Manzo, L. Dauban, B. van Steensel
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
2021 R. Schep, E.K. Brinkman, C. Leemans, X. Vergara, R.H. van der Weide, B. Morris, T. van Schaik, S.G. Manzo, D. Peric-Hupkes, J. van den Berg, R.L. Beijersbergen, R.H. Medema, B. van Steensel
Phosphorylated Lamins in Euchromatin: New Clues to Progeria
2020 S.G. Manzo, B. van Steensel
DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells
2019 A. De Magis, S.G. Manzo, M. Russo, J. Marinello, R. Morigi, O. Sordet, G. Capranico
DNA Topoisomerase I differentially modulates R-loops across the human genome
2018 S.G. Manzo, S.R. Hartono, L.A. Sanz, J. Marinello, S. De Biasi, A. Cossarizza, G. Capranico, F. Chedin
The natural inhibitor of DNA topoisomerase I, camptothecin, modulates HIF-1α activity by changing miR expression patterns in human cancer cells
2014 D. Bertozzi, J. Marinello, S.G. Manzo, F. Fornari, L. Gramantieri, G. Capranico
Novel DNA topoisomerase IIα inhibitors from combined ligand- and structure-based virtual screening
2014 M.N. Drwal, J. Marinello, S.G. Manzo, L.P.G. Wakelin, G. Capranico, R. Griffith
Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation
2013 J. Marinello, G. Chillemi, S. Bueno, S.G. Manzo, G. Capranico
Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II
2012 S.G. Manzo, Z. Zhou, Y. Wang, J. Marinello, J. He, Y. Li, J. Ding, G. Capranico, Z. Miao