Many sectors of industry, such as food, cosmetics, nutraceuticals, and pharmaceuticals, have increased their interest in polyphenols due to their beneficial properties. These molecules are widely found in Nature (plants) and can be obtained through direct extraction from vegetable matrices. Polyphenols introduced through the diet may be metabolized in the human body via different biotransformations leading to compounds having different bioactivities. In this context, enzyme-catalyzed reactions are the most suitable approach to produce modified polyphenols that not only can be studied for their bioactivity but also can be labeled as green, natural products. This review aims to give an overview of the potential of biocatalysis as a powerful tool for the modification of polyphenols to enhance their bioaccessibility, bioavailability, biological activity or modification of their physicochemical properties. The main polyphenol transformations occurring during their metabolism in the human body have been also presented.

Biocatalytic Approaches for an Efficient and Sustainable Preparation of Polyphenols and Their Derivatives / M.L. Contente, F. Annunziata, P. Cannazza, S. Donzella, C. Pinna, D. Romano, L. Tamborini, F.G. Barbosa, F. Molinari, A. Pinto. - In: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. - ISSN 0021-8561. - 69:46(2021), pp. 13669-13681. [10.1021/acs.jafc.1c05088]

Biocatalytic Approaches for an Efficient and Sustainable Preparation of Polyphenols and Their Derivatives

M.L. Contente
Co-primo
;
F. Annunziata
Co-primo
;
P. Cannazza
Secondo
;
S. Donzella;C. Pinna;D. Romano;L. Tamborini;F. Molinari
Penultimo
;
A. Pinto
Ultimo
2021

Abstract

Many sectors of industry, such as food, cosmetics, nutraceuticals, and pharmaceuticals, have increased their interest in polyphenols due to their beneficial properties. These molecules are widely found in Nature (plants) and can be obtained through direct extraction from vegetable matrices. Polyphenols introduced through the diet may be metabolized in the human body via different biotransformations leading to compounds having different bioactivities. In this context, enzyme-catalyzed reactions are the most suitable approach to produce modified polyphenols that not only can be studied for their bioactivity but also can be labeled as green, natural products. This review aims to give an overview of the potential of biocatalysis as a powerful tool for the modification of polyphenols to enhance their bioaccessibility, bioavailability, biological activity or modification of their physicochemical properties. The main polyphenol transformations occurring during their metabolism in the human body have been also presented.
biocatalysis; cosmetics; enzymes; food ingredients; metabolites; nutraceuticals; nutrients; Biocatalysis; Diet; Humans; Vegetables; Dietary Supplements; Polyphenols
Settore CHIM/10 - Chimica degli Alimenti
Settore CHIM/11 - Chimica e Biotecnologia delle Fermentazioni
Settore CHIM/08 - Chimica Farmaceutica
PSR2015-1716MPORR01_M - PIANO DI SOSTEGNO ALLA RICERCA 2015-2017 - TRANSITION GRANT LINEA 1A PROGETTO "UNIMI PARTENARIATI H2020" - PORRINI, MARISA - PSR2015-17 - Piano di sviluppo di ricerca 2015-17 - 2016
Article (author)
File in questo prodotto:
File Dimensione Formato  
JAFC 2021_1.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 1.63 MB
Formato Adobe PDF
1.63 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/889429
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 5
social impact