Newly weaned piglets are commonly exposed to nutrition, envi- ronmental and physiological stress that can negatively affect growth and health. Maternal nutrition may represent a valuable strategy to benefit postnatal offspring development and decrease the susceptibility to diseases in adulthood. The aim of the study was to evaluate the effects of dietary lauric acid saponified with calcium (C12-Ca) given during late gestation to sows and piglets on offspring growth and intestinal health. At 3 weeks before par- turition, 16 sows were randomly assigned to two dietary treat- ment: basal diet (CTR) or basal diet with 1 kg/ton C12-Ca (T). At weaning, 96 piglets were chosen from the litters and distributed in 4 post-weaning dietary treatments belonging to the same descent group: CTR-CTR and T-CTR fed basal diet, CTR-T and T-T fed basal diet plus C12-Ca (1 kg/ton). Body weight (BW), average daily gain (ADG), and average daily feed intake (ADFI) were measured and feed efficiency (FE) was calculated. Fecal samples were taken at 14 and 26 d to evaluate calprotectin (Calp) concen- tration as marker of gut inflammation. Piglets were slaughtered at 26 d and mucosa intestinal samples were collected and used to investigate the impact of C12-Ca on the total antioxidant capac- ity (TAOC) and secretory IgA concentration (SigA). Growth per- formances were analyzed applying a MIXED procedure for repeated measurements and accounting for the effects of treat- ment, time and their interaction. One-way ANOVA was used to analyze Calp, TAOC and SIgA. The differences between means were compared using Tukey’s test and considered statistically significant at p < .05. BW and FE were not affected by C12-Ca while ADG and ADFI resulted higher in CTR-T piglets (p < .05), although there was no significant effect of treatment x time interaction. Calp concen- tration was lower in T-CTR and T-T compared with the other groups (p < .05) after 14 d and no differences were observed at 26 d. SIgA concentration in duodenum was lower in T-CTR and T-T compared to CTR-CTR and CTR-T group (p < .05) whereas no differences were observed for SIgA in ileum and TAOC in both duodenal and ileum mucosa. Although the administration of C12-Ca soaps in the diet of the mothers did not show clear effects on the growth of the offspring, our findings suggest that the administration of C12-Ca soaps modulates intestinal inflammatory status during the first two weeks after weaning, improving gut health.

Long-term administration of calcium laurate to sows and piglets: effects on growth performance, fecal calprotectin and intestinal status of weaning piglets / R. Rebucci, V. Staurenghi, S. Giorgi, A. Agazzi, F. Cheli, A. Baldi, V. Bontempo - In: ASPA 24th Congress Book of Abstract / [a cura di] R. Mantovani, A. Cecchinato. - Prima edizione. - Padova : Taylor & Francis, 2021. - pp. 139-140 (( Intervento presentato al 24. convegno ASPA tenutosi a Padova nel 2021.

Long-term administration of calcium laurate to sows and piglets: effects on growth performance, fecal calprotectin and intestinal status of weaning piglets

R. Rebucci
Primo
;
V. Staurenghi
Secondo
;
S. Giorgi;A. Agazzi;F. Cheli;A. Baldi
Penultimo
;
V. Bontempo
Ultimo
2021

Abstract

Newly weaned piglets are commonly exposed to nutrition, envi- ronmental and physiological stress that can negatively affect growth and health. Maternal nutrition may represent a valuable strategy to benefit postnatal offspring development and decrease the susceptibility to diseases in adulthood. The aim of the study was to evaluate the effects of dietary lauric acid saponified with calcium (C12-Ca) given during late gestation to sows and piglets on offspring growth and intestinal health. At 3 weeks before par- turition, 16 sows were randomly assigned to two dietary treat- ment: basal diet (CTR) or basal diet with 1 kg/ton C12-Ca (T). At weaning, 96 piglets were chosen from the litters and distributed in 4 post-weaning dietary treatments belonging to the same descent group: CTR-CTR and T-CTR fed basal diet, CTR-T and T-T fed basal diet plus C12-Ca (1 kg/ton). Body weight (BW), average daily gain (ADG), and average daily feed intake (ADFI) were measured and feed efficiency (FE) was calculated. Fecal samples were taken at 14 and 26 d to evaluate calprotectin (Calp) concen- tration as marker of gut inflammation. Piglets were slaughtered at 26 d and mucosa intestinal samples were collected and used to investigate the impact of C12-Ca on the total antioxidant capac- ity (TAOC) and secretory IgA concentration (SigA). Growth per- formances were analyzed applying a MIXED procedure for repeated measurements and accounting for the effects of treat- ment, time and their interaction. One-way ANOVA was used to analyze Calp, TAOC and SIgA. The differences between means were compared using Tukey’s test and considered statistically significant at p < .05. BW and FE were not affected by C12-Ca while ADG and ADFI resulted higher in CTR-T piglets (p < .05), although there was no significant effect of treatment x time interaction. Calp concen- tration was lower in T-CTR and T-T compared with the other groups (p < .05) after 14 d and no differences were observed at 26 d. SIgA concentration in duodenum was lower in T-CTR and T-T compared to CTR-CTR and CTR-T group (p < .05) whereas no differences were observed for SIgA in ileum and TAOC in both duodenal and ileum mucosa. Although the administration of C12-Ca soaps in the diet of the mothers did not show clear effects on the growth of the offspring, our findings suggest that the administration of C12-Ca soaps modulates intestinal inflammatory status during the first two weeks after weaning, improving gut health.
Postweaning piglets; calcium laureate; performance; calprotectin
Settore AGR/18 - Nutrizione e Alimentazione Animale
Animal Science and Production Association
Book Part (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/887753
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