Metabolic syndrome (MetS) is a condition characterized by a constellation of reversible major risk factors for cardiovascular disease (CVD) and type 2 diabetes (T2DM). While it has been widely demonstrated that weight reduction by 5–10% decreases CVD and T2DM risk factors, including atherogenic dyslipidemia, on the other hand, its effects on comprehensive serum cytokine profile and endotoxemia are less investigated. Furthermore, the impact of weight loss on these parameters was studied especially in subjects with morbid obesity, often after bariatric surgery; while the studies on the effects of a physiological weight reduction with a balanced hypocaloric diet in overweight and moderately obese subjects showed contradictory results.

Weight Loss Improves Cardio-Metabolic and Inflammatory State in Subjects with Metabolic Syndrome / M. Della Porta, G. Piuri, M. Garziano, M. Barichella, F. Muzio, A.J. Seelam, E. Assi, F. D'Addio, P. Fiorina, B. Cestaro, R. Cazzola. - In: PROCEEDINGS OF THE NUTRITION SOCIETY. - ISSN 0029-6651. - 79:OCE2(2020), pp. E285-E285. ((Intervento presentato al 13. convegno European Nutrition Conference, FENS "Malnutrition in an Obese World: European Perspectives" : 15–18 October tenutosi a Dublin (Ireland) nel 2019 [10.1017/S0029665120002335].

Weight Loss Improves Cardio-Metabolic and Inflammatory State in Subjects with Metabolic Syndrome

M. Della Porta
Primo
;
G. Piuri
Secondo
;
M. Garziano;F. Muzio;A.J. Seelam;E. Assi;F. D'Addio;P. Fiorina;B. Cestaro
Penultimo
;
R. Cazzola
Ultimo
2020

Abstract

Metabolic syndrome (MetS) is a condition characterized by a constellation of reversible major risk factors for cardiovascular disease (CVD) and type 2 diabetes (T2DM). While it has been widely demonstrated that weight reduction by 5–10% decreases CVD and T2DM risk factors, including atherogenic dyslipidemia, on the other hand, its effects on comprehensive serum cytokine profile and endotoxemia are less investigated. Furthermore, the impact of weight loss on these parameters was studied especially in subjects with morbid obesity, often after bariatric surgery; while the studies on the effects of a physiological weight reduction with a balanced hypocaloric diet in overweight and moderately obese subjects showed contradictory results.
metabolic syndrome; lipoprotein; LDL; HDL; Inflammation;
Settore BIO/10 - Biochimica
Settore MED/13 - Endocrinologia
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/740761
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